KEGG   Mus musculus (house mouse): 269254
Entry
269254            CDS       T01002                                 
Symbol
Setx, A130090N03, A930037J23Rik, AOA2, Als4, SCAR1, Sen1, mKIAA0625
Name
(RefSeq) senataxin
  KO
K10706  senataxin [EC:5.6.2.-]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu05014  Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    269254 (Setx)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:mmu03021]
    269254 (Setx)
Transcription machinery [BR:mmu03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     269254 (Setx)
SSDB
Motif
Pfam: AAA_11 AAA_12 AAA_19 UvrD-helicase AAA_30 AAA_22 ResIII Helicase_RecD AAA_16 SLFN-g3_helicase nSTAND3
Other DBs
NCBI-GeneID: 269254
NCBI-ProteinID: NP_932150
MGI: 2443480
Ensembl: ENSMUSG00000043535
UniProt: A2AKX3
Position
2:29013600..29072483
AA seq 2646 aa
MSTCCWCTPGGSSTIDVLKRYASSTGSSEFQTADEDLCYCLECVAEYHRARDEVPFLHEV
LWELETLRLVSHFEKSMKAEAEDDDDLYIVDNNGEEQLFDCSGQDFENKLRVPLFEILKY
PYLLLHERVNELCVEALCRMEQNNCSFQVFDKYPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPAHMYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMEKQSDDDSMDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNESYNREIQNIRNSSIRTKLEPEPHFDDMVTCSQIVYNFN
PEKTKKDSGWRSAICPDYCPNMYEEMETLANVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLYSEVKDVLNQTDAVCDKVTEFFILILISVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFVRSCEKSPGSTSRGAAIMSSLALHSVQSNSVQLACVQLIR
GLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTGQETHELQMCLKQIIRNIKFKMP
QYSTFGDSTSTFKTPPSFKEESDKIDRKHKKNIYCLENCSPVSSKEPMKADTHRVLMKVN
TTEEENFKQHYIDLNEEEQEPLPAELCLKQKSEALFSESAQEQVKISAEKSGKESSSYAP
SNSTSRNGPEWGCDRGVIMSAHSLTDSSSDFMEQVSTSNEDVSLKDGSVGKTSKPSFKLQ
KDEICAKLSHVIKKQIRKSTLVDNIIDLEENTAISDLENCSGTDGGALKEDSIGHNVPSD
PVLDDKHEEQKSQNSSLFKKEIKSEELDNSSSDDEDKLQIQEGRADDDLVSFTEVTDTLV
KAPCEGHVKMVVESRDKEMRESTALTSNLVEGQVPHDSSKPLVAGRQIDLCNITLISQTT
VIQFPSGLSKQNSFQLQKGDKRCLTANQNSAATCRGQVIVISDSDEEEDEDEDERSSSEE
NIKQSKACIGKDCSEHRSLAVNASVEKQLVKEEERYPVEFEDSESQVFEFESSSEVFSVW
QDHKIDSKNSLQGEQKSYVTHVADSTNNNLGCGDSVSEEVVRNKAEGVKEHAGPHSSVSA
EEFCKTGVKKPKRKRYDKVTAEDPQRPSSSVGTDQLPDRRDLTESDLKSADMGMATPSSS
VERDSTILQKSTKSRTHSKPVRKVPASKATKKTHSDTRRGQSKSSCYISCRTSPAIVPPK
KLRQCPEPTSTVEKLGLKKAPRKAFELSQRSLECIVQLRDHGKTVGVVDAPKKAKLISPQ
TLSIKNNKKLLTSQDLQFQRLMRSRSHKKRDFDYKNTDTVRVSRIVQGSDVLEADSDEPD
DHRVSEPLAISNEKQLAKCMLSKTEVAEASSDPWVTGITCLVNQCESRVLSGGVPTDVVM
VSASEDPVDGGAVTVQVGEVASVKAAEPASSSDTDDDDNLFLTQHDPQDMDLCSQLENKT
IIVAHKKDTVQREDSLSRPQLESLSITKCKYKDCVETTKNQGEYCPRHSEAKAADDGLFR
KPGLPLSVARPLRPTTTKIFSSSSASRTANLSKSLESTTLQQSALKNKSSGAQPNLKVTP
PSSMGSQKPVAEVKSLCNIFHFQTPSSSSKQSCKLTFSENRPTSAASPVNILLPSQSIFD
TFIKEVLKWKYQMFLNFDKCGAPTSLCQSISRPVPVRFQDCAEYFNVFLPLIILNAFETV
AQEWLSSPNKENFYQLQLRKFPADYKKYWEFLIYLNESELAKQLHPKENDLVFLAPEKSY
MDRHGMQDCSHYYCGYVHKFRRTSVMRSGKAECSLCIQTQDTLPASVKNLTRCIVISSLV
TTQRKLKAMSLLSSRNQLARAVLNPNPMDFCTKDLLTTTSERIVAYLKDFNEDQKKAIET
AYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRKGHSDENFNAKIKQNRVL
VCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLGPEKSINTEVLKFSLDSQ
VNHRMKKDLPSHIQEMLRRKEILDAQLDELSRQRALCRGGREMQRQELDEHIAIVSKERQ
ELASKIKEVQGRPQRAQNTIILESHVICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAG
QSCEVETLSPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCKLLEENVEQN
MIGRLPVLQLTIQYRMHPDICLFPSNYVYNKNLKTNRLTESIRCSSEWPFQPYLVFDVGD
GSERRDNDSYINVQEIKLVMEIIKLIKEKRKDISFRNIGIITHYKAQKTMIQKDLEKEFD
KKGPAEVDTVDAFQGRQKDCIIVTCVRASAVQGSIGFLASLQRLNVTITRAKYSLFILGH
LRTLMENQHWYELIQDAQKRGAIIKTSDPNYRHDAMKILKLKPVLQRSLTHPPATAPEAP
RPQGGLPSNRLDSGLATTSFAASLYHTPSDTVTSKGPERPLLQDRLRDPRLLRRLDAEAK
GTFLKDPQPVSPQLPGVVHLLGEPGFPVVFQDLGFVVPPSTAIVAPLGSHRSPMQAEPPP
AHPAAAASTSKRKYSDPDAGLSHKREPRAFSGEQGRHGSVTHHVLRSTDWDRRRLDDSSA
KRRQFL
NT seq 7941 nt   +upstreamnt  +downstreamnt
atgagcacatgctgttggtgtactccaggtgggtcttccaccattgatgtcctaaagcgc
tatgcatctagcactgggtcaagtgaatttcagacagctgatgaagacctctgctactgc
ttagagtgtgtggctgagtaccaccgagccagagatgaggtgccgttcttgcacgaggtt
ttatgggagctagaaaccttacgcctcgtaagtcactttgagaagtccatgaaggcagaa
gctgaagatgacgatgatttatatatagtagacaacaatggagaggaacagctgtttgac
tgtagtggccaagattttgaaaataagcttcgagttcctctttttgaaatactgaagtac
ccttacttgcttctgcatgagcgtgttaatgaactgtgtgtggaagcgctttgccgaatg
gaacaaaacaattgctcctttcaggtttttgacaaatatccaggcatctatttgtttttg
gttcatcccaatgaaatggttcggcgatgggctattctgactgcaagaaacctggggaag
gtggacagagatgactattatgacttacaggaagttttaacttgcctttttaaagtcatt
gagctggggcttttggaaagtccagacatttacacatcttctgtgcttgaaaaaggcaaa
ctgatccttttgcctgcacacatgtatgatactaccaactacaaaaactattggctaggt
atttgcatgttgttgactattcttgaggagcaagccatggattcactgttgctgggctca
gacaagcaaaatgattttatgcaatcaattcttcacaccatggagaagcaatcggatgat
gatagcatggatcctttttggccagcattacactgtttcatggtgattcttgatcgcctt
ggatctaaggtatggggtcaacttattgaccctattgaagcatttcaaaccatcattaac
aacgagagctacaacagagagatccagaatatacggaacagctccataaggaccaagtta
gaaccggagccacattttgatgatatggtgacgtgcagccagattgtttataactttaat
cctgaaaagaccaaaaaggattctgggtggagatcagccatttgtccagattattgtcca
aacatgtatgaagaaatggaaacattagccaatgtacttcagtcagatattggtcaagat
atgcgtgttcataacagcacctttctgtggttcataccttttgttcagtcactcatggat
cttaaggatttgggtgtggcttacatagtagaagttattcatcatctatactcagaagtc
aaagatgtcctcaaccagacagatgctgtgtgtgacaaagtcactgaattttttattctg
attttaatatcagtgattgagctgcatagaaataaaaaatgcttgcatctgctgtgggtg
agttctcagcagtgggtagaagctgttgtgaagtgtgccaagcttcctactaccgcattt
gtccggagttgtgagaagtcacctggaagtacctccagaggagcagcaataatgtcgtcc
ttggcgttgcattcggtgcagtctaactctgtccagcttgcttgtgtacagttgattaga
ggtctcctcaaagaaggttatcagcttggtcagcaaacactttgtaagcggttctgggat
aagcttaacttattccttcgaggaaatttgtctctgggttggcaattgactggtcaagaa
acccatgagttacaaatgtgtttgaaacaaataattagaaacataaaattcaaaatgccc
caatatagcacttttggggattcaacttctacatttaaaacccctccatcttttaaagaa
gaaagtgataaaatagacaggaagcataaaaaaaacatttattgtttggaaaattgcagt
ccagtgtcttctaaagagccaatgaaagctgacacccatcgagtattgatgaaagtaaat
actacagaagaggagaacttcaagcagcattacattgatttgaatgaagaagagcaagag
cctcttccagctgagttgtgcttgaagcagaaaagtgaggcccttttttctgaaagtgct
caagagcaagttaaaattagcgcagagaagtctgggaaagaaagctcttcatatgcacca
tcaaatagtacttcaagaaatggtccagaatggggatgtgacagaggagtgataatgtca
gcacattcattgactgattctagcagtgattttatggaacaggtatctacatcaaatgaa
gatgtctcattaaaggatggctctgttggtaaaacttcaaaaccaagtttcaaattacag
aaagatgaaatttgtgcaaagttatcacatgtcataaagaagcaaatcaggaaaagtact
ttggtagataatattatcgatctagaggaaaatacagctatatctgaccttgagaactgt
tcaggaacagatggaggagctctaaaggaagatagtattggacacaatgtcccttcagac
cctgttctggatgacaagcatgaagagcaaaaatctcaaaacagttcattattcaagaaa
gagataaagagtgaggagttggataatagtagttctgatgatgaagacaagcttcaaatc
caggaaggccgtgctgacgatgatttggtatcatttacagaagttactgatacactggtg
aaagctccatgtgagggtcatgtaaagatggtagttgaatcaagagataaggaaatgaga
gagagtacagcgttgacttctaacttggtagaaggacaggtgcctcatgacagtagcaag
cctttggttgcaggtcgtcaaatagacctctgtaacataactttaatatctcaaaccact
gttattcaatttccatcaggtttaagtaaacagaattcatttcagctacaaaaaggtgat
aaaagatgtttgacagctaaccaaaacagtgctgccacctgccgtggacaagttattgtg
atttcagattctgacgaagaagaggatgaggatgaagatgaaagaagtagtagtgaggaa
aacatcaaacagagtaaagcatgcatagggaaagactgctcagagcatcgtagcttggca
gttaatgccagtgtggagaagcagcttgtaaaagaggaagaaaggtaccctgtagaattt
gaagactctgaatctcaggtttttgagtttgaaagctcatctgaagtcttttcagtttgg
caagatcataaaatagacagcaaaaactcccttcaaggggaacagaagagctatgtaact
catgtagctgatagtacaaacaataacttgggttgtggtgactctgtgtctgaagaggtt
gttagaaacaaagcagagggagttaaagagcatgcaggaccacatagtagtgtttctgct
gaggaattttgtaaaactggagtaaaaaaacctaagaggaaacgctatgacaaagttaca
gctgaagatcctcagaggccttcctcttctgttggaactgatcaattgcctgatcgcaga
gatcttactgaaagtgatttaaagagtgcagacatggggatggcaactcccagttcaagt
gttgagagagattctacaattttacagaagtctacaaaatctcgaactcactcaaaacct
gttaggaaagttccagcctctaaggcaactaagaaaacacattcagacaccagaagagga
cagtctaagagttcatgttacataagttgtagaacttctcctgctattgtgccaccaaag
aagcttcgtcagtgtccagagccaacttcaacagttgaaaaacttggtctgaaaaaagcc
cctaggaaggcatttgagttgtcccagaggtctctggagtgtatagtccaattacgtgac
cacgggaagactgttggagtagttgacgcccccaagaaagctaaattaatttctcctcag
actctttctatcaaaaataataagaagcttctgacaagccaggatcttcaatttcaaagg
cttatgagatccagatcacataaaaaacgagactttgattacaaaaatactgatactgta
agagtgtcacgcatagtacagggatcagatgtacttgaagcagactctgatgagccagat
gatcatagagtaagtgagccacttgccatcagtaatgaaaaacagttagcaaaatgcatg
ctttccaaaacagaagtggcagaagcctcttctgatccttgggtgacaggtataacttgt
cttgtgaaccagtgtgaatctagagtgttaagtggaggagtgccaacagatgtggtgatg
gtctctgcttcagaggaccctgtggatggaggtgctgtcacagttcaagttggggaggtg
gcatctgtgaaagctgcagagccagcgtctagtagtgatacagatgatgatgacaactta
ttcctaacacaacatgatcctcaagatatggatctgtgctcacagttggaaaataaaacc
attatcgtggctcataaaaaagatacagttcagagagaagattctttaagtcggcctcag
ttggagtctttgagtatcacaaagtgtaaatacaaagactgtgtcgaaactacaaaaaac
cagggtgaatactgcccaagacactctgaagctaaagcagcagatgacggcctgttccgt
aaacctggcttgcctctttctgtagccaggcccttgagacctactactaccaagatattt
agctcaagcagcgcttcacgaactgccaatctttccaagtctttggaaagtactacactt
cagcagtcagcactaaaaaataagtcaagtggagcgcagcctaatttgaaggtgacacca
ccctcttccatgggttctcagaagccagtggctgaggtgaaaagtctatgcaatattttt
cattttcagactccaagcagttccagcaaacagagttgcaagcttacatttagtgagaac
aggcctacatcagctgcttctccagtgaatattctcttgccatcgcagtctatctttgac
accttcattaaagaggtcttaaaatggaaataccaaatgtttttgaactttgataagtgt
ggtgctccaacaagtctctgtcagtctatctcaagacctgtgcctgtccgatttcaagat
tgtgcagaatattttaatgtttttctacctttgattatattgaatgcttttgaaacagtg
gcacaggaatggctgagctctccaaataaagagaatttctatcagttgcaattacgaaaa
tttccagctgactataaaaaatactgggagtttctgatttacttgaacgaatctgaactt
gctaaacagcttcacccaaaggaaaatgatctggtgtttctggctcctgagaagagttat
atggacaggcatggcatgcaagattgcagtcactattactgtggctatgttcataagttt
cgtcgcacttcagttatgcgcagtgggaaagctgagtgttcattatgcatacagacacaa
gataccttgccagccagtgtaaaaaatcttacaagatgcattgtgatcagttctctggta
actacacagaggaaattgaaagccatgtctctgttgagtagtcggaaccagttggccaga
gctgttctaaatccaaaccccatggacttctgtaccaaagatctactaactacaacttct
gaaagaattgttgcctacttaaaagactttaatgaagaccaaaagaaagccatagaaact
gcatatgccatggtgaaacactcaccatccgttgccaaaatctgtctgattcatggacca
cctggaacaggaaaatccaaaactattgttggtctcttgtaccgcttactgacagagaac
cagaggaagggccattcagatgaaaatttcaatgccaaaatcaaacaaaatcgagtcctc
gtgtgtgcaccttccaatgcggcggttgatgaacttatgaaaaaaattatcctcgaattt
aaagaaaaatgtaaagacaagaagaatcctttgggaaactgtggagatataaatttagta
cgactaggtccagaaaagtctattaatacagaggtcttaaaattcagtttggacagccaa
gtcaaccatagaatgaaaaaagacttgccttctcatattcaagaaatgcttagaagaaaa
gaaattctagatgctcaacttgatgagctttctcgtcagcgagctctgtgccgaggtggg
cgggagatgcagaggcaagaattagatgaacacattgccatagtctcaaaagaaaggcaa
gaacttgcttcgaaaattaaagaggttcagggacgcccacagagagcacagaataccatc
atcttggagtcccatgtcatctgctgcacattgagcactagtggtggtttattgcttgag
tctgcttttcgagggcaagggggtgtccccttcagttgtgtcatcgtagatgaggctggg
cagtcttgtgaagttgagacactttctccactcatccaccgctgcaataaacttatccta
gtaggagaccccaaacagctccctcccacagtcatctctatgaaagcacaggagtatggc
tatgaccagtcgatgatggcccgattctgcaagctgctggaagagaatgtggagcagaac
atgattggcaggctgccggtgttacagcttaccattcagtacaggatgcatccagacata
tgtcttttcccttctaattacgtttataacaaaaacctgaagacaaatagattgactgaa
tccattcgatgttcatcagagtggccatttcagccctacctcgtgtttgatgttggagat
ggttcagaacgacgggataatgactcatatataaatgttcaagaaataaagttggtgatg
gaaataattaaacttattaaagagaaaagaaaagatatttccttccgaaatattggcata
ataacccattacaaggctcagaagacgatgatccagaaggatttggagaaagaatttgat
aagaaaggacctgcagaagtggacacagtagatgccttccagggccggcagaaagactgt
atcatcgttacctgtgtcagggcaagtgctgtgcaaggctcaataggattcctggcaagt
ttgcagagattgaatgtcaccattacacgagccaagtatagcctctttatccttggacat
ttgaggactctgatggaaaaccagcattggtatgaactgattcaggatgctcagaagcgt
ggggccattattaagaccagtgacccaaactatagacatgacgcaatgaagattctgaaa
ctgaagcctgtgctacagaggagtctgacccatcccccagccactgccccggaggcaccc
agaccccagggtggcttgcccagcaacagactggacagtggacttgccacaacatctttt
gctgcttctttgtatcacacaccctctgatactgtcacttcaaagggacctgaaaggcca
cttcttcaagaccgacttcgagatccacgactactcaggagattggatgctgaagccaag
ggaacattcctgaaggatccacagcccgttagcccccagctccccggggtagttcatctc
ttgggagagcctggcttccctgtggttttccaggacctaggttttgttgtgccgccatcc
actgccattgttgctcctctgggcagccacaggtcacctatgcaggctgagccaccacct
gctcaccctgctgctgccgcctccacaagtaagaggaagtacagtgacccagatgctggg
ctcagccacaaaagagaacccagggccttcagtggagagcaggggaggcatggctctgtg
actcatcacgtgctgagaagcactgactgggacaggaggaggctggatgacagcagtgcc
aagaggagacaatttctatag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (60)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (53)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (27)   
   RefSeq(nuc) (7)   
   GenBank (10)   
   EMBL (10)   
Protein domain (11)   
   Pfam (11)   
All databases (109)   

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