KEGG   Mus musculus (mouse): 69719Help
Entry
69719             CDS       T01002                                 

Gene name
Cad, 2410008J01Rik, AU018859, Cpad
Definition
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (EC:2.1.3.2 3.5.2.3 6.3.5.5)
Orthology
K11540  
carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
mmu  Mus musculus (mouse)
Pathway
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Metabolic pathways
Module
Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Metabolism
  Nucleotide metabolism
   00240 Pyrimidine metabolism
    69719 (Cad)
  Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    69719 (Cad)
Enzymes [BR:mmu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     69719 (Cad)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     69719 (Cad)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     69719 (Cad)
Peptidases [BR:mmu01002]
 Cysteine Peptidases
  Family C26: gamma-glutamyl hydrolase family
   69719 (Cad)
 Metallo Peptidases
  Family M38: beta-aspartyl dipeptidase family
   69719 (Cad)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
Vega: 
UniProt: 
Position
5 B1; 5
AA seq 2154 aa AA seqDB search
MAALVLEDGSVLQGRPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNY
GIPSDEEDEFGLSKWFESSEIHVAGLVVGECCPTPSHWSANCTLHEWLQQRGIPGLQGVD
TRELTKKLREQGSLLGKLVQKGTEPSALPFVDPNARPLAPEVSIKTPRVFNAGGAPRICA
LDCGLKYNQIRCLCQLGAEVTVVPWDHELDSQKYDGLFLSNGPGDPASYPGVVSTLSRVL
SEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGTGRCFLTSQNHGFAVD
ADSLPAGWAPLFTNANDCSNEGIVHDSLPFFSVQFHPEHRAGPSDMELLFDVFLETVREA
AAGNIGGQTVRERLAQRLCPPELPIPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI
KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITLHYVTQVIRNERPDGVLLTFGGQT
ALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQ
AQAAAERLGYPVLVRAAFALGGLGSGFASTKEELSALVAPAFAHTSQVLIDKSLKGWKEI
EYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRRTAIKVTQHLG
IVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRN
SVTGGTAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL
RMVDENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVERLYELTRIDCWFLHRM
KRIVTHAQLLEQHRGQALPQDLLHQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAV
KQIDTVAAEWPAQTNYLYLTYWGNTHDLDFRAPHVLVLGSGVYRIGSSVEFDWCAVGCIQ
QLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLP
NNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCHT
VGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAV
ACDGIVSAIAISEHVENAGVHSGDATLVTPPQDITPKTLERIKAIVHAVGQELQVTGPFN
LQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRIIMGEKVEPVGLMTGSGVVG
VKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPEKNILLTIG
SYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSI
LDQLAENHFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEAL
GQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGVTMV
CAMPNTRPPIIDAPALALAQKLAEAGARCDFTLFLGASSENAGTLGAVAGSAAGLKLYLN
ETFSELRLDSVAQWMEHFETWPAHLPIVAHAERQSVAAVLMVAQLTQRPVHICHVARKEE
ILLIKTAKAQGLPVTCEVAPHHLFLNREDLERLGPGKGEVRPELGSREDMEALWENMAVI
DCFASDHAPHTLEEKCGPKPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIF
HLPLQEDTYVEVDLEHEWTVPSHMPFSKARWTPFEGQKVKGTVRRVVLRGEVAYIDGQVL
VPPGYGQDVRKWPQGVVPQPPPSTPATTEITTTPERPRRVIPGLPDGRFHLPPRIHRASD
PGLPAEEPKEKPPRKVVEPELMGTPDGPCYPAPPVPRQASPQNLGSSGLLHPQMSPLLHS
LVGQHILSVKQFTKDQMSHLFNVAHTLRMMVQKERSLDILKLAAKHCRRPVINAGDGVGE
HPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVSLRYVAPPSLRM
PPSVRDFVASRGTKQEEFESIEEALPDTDVLYMTRIQKERFGSVQEYEACFGQFILTPHI
MTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLATVLGRF
NT seq 6465 nt NT seq  +upstreamnt  +downstreamnt
atggcggccctggtgttggaggacgggtcggtgctgcagggccggccctttggggccgct
gtgtcgactgctggggaagtggtgtttcagaccggcatggtcggctacccagaggccctc
actgacccttcctacaaagctcagatcctagtgctaacgtatcctctcatcggcaactac
ggcattccctcagatgaagaggacgagttcggcctgagcaagtggtttgaatcctcggag
atccacgtggcgggacttgtagtgggagaatgctgtcccacacccagccactggagtgcc
aactgcaccctgcatgagtggctgcaacagcgtggcatccccggcctgcaaggagtggac
actcgggagctgactaagaagttgcgggagcaagggtctcttttggggaagctggtccag
aaagggacagagccgtcagccctgccattcgtggaccccaatgccaggcccctggcacca
gaggtctctattaagactccacgggtattcaatgcagggggtgcccctcggatctgtgct
ctggattgtggcctcaagtataatcagatccgatgtctctgccagcttggggctgaagtt
accgtggtaccctgggaccacgagttagacagtcagaaatatgacggtctcttcctaagt
aatggacccggtgaccctgcctcttacccgggtgtggtgtccacactgagccgagtcttg
tctgaacctaacccccgacctgtgtttggaatctgccttggacaccagctgttggcttta
gccatcggggccaaaacttacaagatgagatacggaaaccgaggccacaaccagccctgt
ttactggtgggcactgggcgctgctttctgacgtcccagaatcatgggtttgcagtggac
gcagattcgctgccagcaggctgggctcctctgttcaccaatgccaatgactgttccaat
gaaggcatagtgcacgacagcctgcccttcttcagtgtccagtttcacccagagcaccgg
gccggcccttcagatatggaactgctcttcgatgtatttctagaaactgtgagagaggct
gcagctgggaacattgggggccagacagtaagagaacgcttggctcagcgcctctgtccc
cctgagctccccattcctggttctgggctcccgcctccacgaaaggttctaatcctaggc
tcagggggcctctccattggccaagctggagaatttgactactcgggctctcaggcaatt
aaagccctaaaggaggaaaacatccagacattactaatcaaccccaacattgccacagtg
cagacttctcaggggctggcagacaaggtctatttccttcccataacacttcactacgta
acccaggtaattcgtaatgaacgcccagatggtgtgttactgacttttgggggtcaaaca
gccctgaactgcggtgtggagctgaccaaagctggggtactggctcgatatggggtccgg
gtcttgggtacacccgtggagaccattgaactgactgaggaccgacgagccttcgctgcc
aggatggctgagatcggagagcatgtcgcccccagtgaagcggcaaattctcttgaacag
gctcaggcagctgccgagcgactaggctaccctgtgctggtgcgagcagcctttgccctg
ggtggtctcggttctggctttgcttccaccaaagaggaactctcagctcttgtggctcca
gcttttgcccataccagtcaggtgctgatagacaagtctctgaagggctggaaggagatt
gaatatgaggtggtgagagacgcctatggcaactgcgtaacggtatgcaacatggagaac
ttagacccactgggcattcatactggtgaatccatagtggtggctccgagccagacactg
aatgacagagagtaccagcttctgcgacggacagctatcaaggtcactcagcacctgggc
attgtcggggagtgcaatgtacagtatgctttgaaccccgagtctgagcagtattacatc
attgaagtgaatgccaggctctcccgaagctctgccctggccagtaaggccacaggctat
ccactagcctatgtggcagccaagctagcattgggcattcccctgccagagctcagaaac
tctgttacgggaggaacagcagcctttgagcccagcctggactactgcgtggtaaagatt
cctcgctgggacctcagcaagttcctacgtgtcagtacgaagattgggagttgcatgaag
agtgttggcgaggtcatgggcatcgggcggtcctttgaggaggccttccaaaaggccctg
cgcatggtcgatgagaactgcgtaggcttcgaccatacagtaaagccagtcagcgacatg
gagctggagactccgacggataagcggatctttgtggtggctgccgctctgtgggctggc
tactctgtggagcgcctctacgagctcacccgcattgattgctggttcctgcaccggatg
aagcgcattgtgacccacgcccagttgctggaacaacaccgtggacaagctttaccccaa
gacctgctgcaccaggccaagtgcctcggcttctcagacaagcagattgccctggcagtc
ctgagcacagagctggctgttcggaagctgcgtcaggaactggggatctgcccagcggtg
aaacagattgacacagttgcagctgagtggccagcccagacaaattacctgtacctgaca
tactggggcaacacccatgacctcgactttcgggcacctcacgtcctggtccttggctct
ggtgtctaccggattggctccagtgttgagtttgattggtgtgctgtgggttgcatccag
cagctccggaagatgggttataagaccatcatggtgaactacaacccagagacagtcagc
accgactatgatatgtgtgaccgactctactttgatgagatctcttttgaggtggtgatg
gacatctatgagttagagaaccccgaaggtgtgatcctgtccatgggtgggcagctgccc
aacaacatggccatggctttgcatcggcagcagtgccgagtgctgggcacctcccccgaa
gccatcgactcagccgagaaccgattcaagttctcccggctcctagataccatcggtatc
agccagcctcagtggcgagagctcagtgaccttgagtctgctcgccagttctgccacacg
gtcgggtacccctgcgtagtgcgcccctcctatgtgctcagcggtgctgctatgaatgtg
gcgtacaccgacggggacctggagcgtttcctgagcagtgcggccgccgtctctaaggag
caccccgtagtcatctccaagttcattcaggaagcaaaggagatcgacgtggacgcggtg
gcctgtgacggcatcgtgtcggccattgccatctctgagcacgtggagaatgcaggtgtg
cattcaggtgatgccacgctggtgacccccccacaagacatcaccccgaaaactctggag
cggatcaaagccattgtgcatgctgtgggccaggagctacaggttacaggacccttcaat
ctgcagctcattgccaaggatgaccagctgaaggttattgaatgcaacgtgcgtgtatct
cgctctttccccttcgtgtccaagacactgggtgttgatctagtagccttggccacaagg
atcatcatgggggagaaagtagagcccgtggggctcatgactggctctggagtcgtggga
gtaaaggtacctcagttctccttctcacgcttggccggtgccgacgtggtacttggtgtg
gagatgaccagtactggagaggtggccggcttcggagagagccgttgtgaagcctacctc
aaagccatgctcagcactggctttaagatcccagagaagaacatcctgctgactattggc
agctacaagaacaaaagtgagctgctcccaactgtgcggttgctggagagcctgggctac
agcctctatgccagcctgggtacggcagacttctacactgagcacggggtcaaggtaaca
gctgtggactggcactttgaagaggcggtggatggtgagtgcccaccacaacggagcatc
ttggatcagctggctgaaaatcactttgagctagtgattaacctgtccatgcgtggggct
gggggtcggcgtctttcctccttcgttaccaagggctaccgtacccggcgtctggccgct
gatttctctgtgcctctcatcattgacatcaagtgcaccaaactctttgtggaggcccta
ggccagatcggcccagcccctcctttgaaagtgcacgttgactgcatgacctcccagaag
ctagtgcgcctgcccggattgattgatgtccacgtgcaccttcgggaaccaggtgggaca
cacaaagaggactttgcctcaggcacagctgctgccttggctgggggtgtcaccatggtt
tgtgctatgcctaatacccgaccccccatcattgatgctcctgctctcgcccttgcccag
aagctggcagaggctggcgcccgctgtgactttaccttattccttggagcctcatctgag
aacgcggggactctgggtgctgtggccggctctgcagcaggcctgaagctctacctcaac
gagaccttctctgagctgcggctggacagtgtggcccagtggatggagcattttgaaacc
tggcctgcccacctccccattgtggcccatgcagagcggcagagtgtcgctgcggtcctc
atggtggctcagctgacccagcgtccagtgcacatatgtcatgtggctcggaaggaagag
atcctgttgattaaaactgcaaaggcgcaggggctgccagtgacctgtgaggtcgctcct
caccacctgttcctaaaccgggaagacttggagcgcctgggacctgggaagggagaggtc
cgtcctgagcttgggtcccgagaggatatggaagccctgtgggagaatatggcagtcatc
gactgttttgcctcagaccacgctccccataccttggaagagaagtgtgggcccaagcct
ccacctggcttcccgggcctagagaccatgttgccgctgctgctgacagctgtgagcgag
ggccgcctcagtctggatgacctgctgcagcgattgcaccacaaccctcggcggatcttc
cacctgcctctccaggaggacacctatgtagaggtggatctggagcatgagtggacagtc
cccagccacatgcccttctctaaggcccgctggaccccatttgaaggacagaaggtgaag
ggcacagtgcgccgtgtggtcttgcgaggggaggtcgcctatattgatggacaggtgctg
gtacccccgggctatggacaagatgtacggaagtggccgcagggggttgttccccagccc
cctccttcaactcccgccaccaccgaaatcaccacgacacctgagcgaccacgccgagtc
atcccgggccttcctgatggccgcttccacctgccaccccgcatccaccgggcctctgac
ccaggtctgccagctgaggaacctaaagagaagccacccaggaaggtagtggaaccagag
ctgatgggaacccctgatggtccctgctaccctgcaccaccagtacctagacaggcatca
ccccagaacctagggtcttctggcctgctgcacccccagatgtcgcccctactgcactcc
ctagtgggccagcacatcctgtctgtcaagcagttcactaaggatcagatgtctcatctg
ttcaatgtggcgcacacgctacggatgatggtacagaaggagcggagcctcgacatcctg
aagctggcagccaagcactgtcgcaggccagtgatcaatgctggggatggagttggggag
caccccacacaggccctgctggacatcttcaccattcgagaagagctggggactgtcaat
ggcatgacgatcactatggtcggtgacctgaagcatggacgcacagtgcactccctggcc
tgcctgctcacccagtaccgtgtgagcctacgctacgtggcacctcccagcctgcgcatg
ccacccagtgtacgggactttgtggcctcccgaggcaccaagcaggaggagtttgagagc
atcgaggaggcgctgcccgacacagacgtgctctacatgactcggatccagaaagaacga
tttggctctgtccaggaatatgaagcttgctttggtcagttcatcctcactcctcacatc
atgacccgggccaagaagaagatggtggtgatgcacccaatgccccgtgtcaatgagata
agtgtggaggtggactcggacccccgggcagcctacttccgccaagctgagaacggcatg
tacatccgcatggccctgcttgccaccgtgcttggccgtttctag

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