| Entry |
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| Symbol |
Nrg1, 6030402G23Rik, ARIA, D230005F13Rik, GGF, GGFII, HRG, HRGalpha, Hgl, NDF, Pro-NRG1, SMDF
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| Name |
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| KO |
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| Organism |
mmu Mus musculus (house mouse)
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| Pathway |
| mmu01521 | EGFR tyrosine kinase inhibitor resistance |
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| Brite |
KEGG Orthology (KO) [BR:mmu00001]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
211323 (Nrg1)
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
211323 (Nrg1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
211323 (Nrg1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:mmu04052]
211323 (Nrg1)
00536 Glycosaminoglycan binding proteins [BR:mmu00536]
211323 (Nrg1)
Cytokines and neuropeptides [BR:mmu04052]
Cytokines
Growth factors (RTK binding)
211323 (Nrg1)
Glycosaminoglycan binding proteins [BR:mmu00536]
Heparan sulfate / Heparin
Growth factors/receptors
211323 (Nrg1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Position |
8:complement(32299493..33381858)
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| AA seq |
645 aa
MSERKEGRGKGKGKKKDRGSRGKPAPAEGDPSPALPPRLKEMKSQESAAGSKLVLRCETS
SEYSSLRFKWFKNGNELNRRNKPQNVKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
DSASANITIVESNDLTTGMSASTERPYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLI
KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEA
EELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRQKLHDRLRQSLRSERNNMVNIANG
PHHPNPPPENVQLVNQYVSKNVISSEHIVEREVETSFSTSHYTSTAHHSTTVTQTPSHSW
SNGHTESIISESHSVIMMSSVENSRHSSPAGGPRGRLHGLGGPRECNSFLRHARETPDSY
RDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSVAVSPFVEEE
RPLLLVTPPRLREKKYDHHPQQLNSFHHNPAHQSTSLPPSPLRIVEDEEYETTQEYEPIQ
EPIKKVTNSRRAKRTKPNGHIANRLEMDSNPSSVSSNSESETEDERVGEDTPFLGIQNPL
AASLEVAPAFRLAESRTNPAGRFSTQEELQARLSSVIANQDPIAV |
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| NT seq |
1938 nt +upstreamnt +downstreamnt
atgtctgagcgcaaagaaggcagaggcaaggggaagggcaagaagaaggaccggggatcc
cgcgggaagcccgcgcccgccgaaggcgacccgagcccagcattgcctcccagattgaaa
gagatgaaaagccaggagtcagctgcaggctccaagctcgtgcttcggtgtgaaaccagc
tctgagtactcctcactcagattcaaatggttcaagaacgggaatgagctgaaccgtagg
aataaaccacaaaacgtcaagatacagaagaagccagggaagtcagagcttcgaatcaac
aaagcgtccctggctgactctggagaatatatgtgcaaagtgatcagcaagttaggaaac
gacagtgcctctgccaacatcaccattgttgagtcaaacgacctcaccactggcatgtca
gcctcaactgaaagaccctatgtgtcctcagagtctcccattagaatatcagtttcaaca
gaaggcgcaaatacttcttcatccacatctacatccacgactgggaccagccatctcata
aagtgtgcggagaaggagaaaactttctgtgtgaatggaggcgagtgcttcatggtgaag
gacctgtcaaacccctcaagatacttgtgcaagtgcccaaatgagtttactggtgatcgt
tgccaaaactacgtaatggccagcttctacaagcatcttgggattgaatttatggaagcg
gaggagctctaccagaagagggtactgacaattactggcatctgtatcgccctgttggtg
gtcggcatcatgtgtgtggtggcctactgcaaaaccaagaaacagcggcagaagcttcat
gatcggctccggcagagccttcggtcagaacgaaacaacatggtgaacatagcgaatggc
cctcaccatccaaacccaccaccagagaatgtgcaactggtgaatcaatatgtatctaaa
aacgtcatctccagtgagcatattgtggagagagaagtggagacctccttttccaccagt
cactacacttccacagctcatcactccacgactgtcacccagactcctagtcacagctgg
agtaatgggcacacagaaagcatcatttcagaaagccactctgtaatcatgatgtcatcg
gtagagaacagcaggcacagcagcccagctgggggcccacgaggacgtcttcatggcctg
ggaggccctcgcgaatgtaacagcttcctcaggcatgccagagaaacccctgactcctac
agagactctcctcatagtgaaaggtatgtatcagccatgaccaccccggctcgtatgtca
cctgtagatttccacacgccaagctcccctaaatcgcccccttcggaaatgtctccaccc
gtgtccagcatgacggtgtccatgccctctgtggcagtcagcccctttgtggaagaagag
aggcctctgcttcttgtgacgccaccgaggctacgggagaagaagtatgatcatcacccc
cagcaactcaactcctttcatcacaaccctgcacatcagagtaccagcctcccccctagc
ccattgaggatagtggaggatgaggaatacgaaacgacccaggagtatgagccaattcaa
gagcctattaagaaagtcaccaatagccggcgggccaaaagaaccaagcccaatggccac
attgccaataggttggaaatggacagcaacccaagttctgtgagcagtaactcagaaagt
gagacagaagatgaaagagtaggtgaagatacaccattcctgggcatacagaaccccctg
gcagccagccttgaggtggcccctgccttccgtctggctgagagcaggactaacccagca
ggccgcttctccacacaggaagaattacaggccaggctgtctagtgtaatcgctaaccaa
gaccctattgctgtataa |
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