KEGG   Mycobacterium tuberculosis RGTB327: MRGA327_04685
Entry
MRGA327_04685     CDS       T01775                                 
Name
(GenBank) methylmalonate-semialdehyde dehydrogenase
  KO
K00140  malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
Organism
mtg  Mycobacterium tuberculosis RGTB327
Pathway
mtg00280  Valine, leucine and isoleucine degradation
mtg00410  beta-Alanine metabolism
mtg00562  Inositol phosphate metabolism
mtg00640  Propanoate metabolism
mtg01100  Metabolic pathways
mtg01200  Carbon metabolism
Brite
KEGG Orthology (KO) [BR:mtg00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    MRGA327_04685
   00562 Inositol phosphate metabolism
    MRGA327_04685
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    MRGA327_04685
  09106 Metabolism of other amino acids
   00410 beta-Alanine metabolism
    MRGA327_04685
Enzymes [BR:mtg01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.18  malonate-semialdehyde dehydrogenase (acetylating)
     MRGA327_04685
    1.2.1.27  methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
     MRGA327_04685
SSDB
Motif
Pfam: Aldedh LuxC
Other DBs
NCBI-ProteinID: AFE15717
Position
complement(844918..846450)
AA seq 510 aa
MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA
WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL
KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP
SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA
TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR
ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL
TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE
YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA
IQFYTKVKTVTSRWPSGIKDGAEFVIPTMS
NT seq 1533 nt   +upstreamnt  +downstreamnt
atgaccacacagatttcacatttcatcgacggacaacgcaccgccggccagtccacgcgc
tcggccgacgtcttcgaccccaacaccggccagatccaggcgaaggtaccgatggccggc
aagtcagacatcgacgcggccgtggcctccgcggtcgaggcccaaaagggctgggccgca
tggaatccccagcgccgtgcccgggtgttgatgcggtttatcgaactggtcaacgacacc
atcgacgagttggccgagctgttgtcgcgtgagcacggcaaaacgctggccgacgcccgc
ggcgacgtccagcgcggcatcgaggtaatcgagttctgcctgggcattccccacctgctc
aagggcgagtacaccgagggtgccggccccggcatcgacgtctattcgctgcggcagccc
ctgggtgtggtcgcggggatcaccccgttcaacttcccggcgatgattccgctgtggaag
gccggcccggccctagcgtgcggcaacgccttcgtgctcaagccaagtgagcgcgacccg
tcggttccggtgaggctggccgagctgttcatcgaggcgggcctgccggcgggcgtgttc
caggtggtgcacggcgacaaggaggccgtcgacgccatcctgcaccaccccgacatcaag
gccgtcggcttcgtcggcagctcggatatcgctcagtacatctacgctggtgccgccgcc
accggcaagcgggcgcagtgtttcggcggtgccaagaaccacatgatcgtgatgcccgac
gcggacctggatcaggccgtggacgcactgatcggcgccggatacggcagcgccggcgaa
cgctgcatggcgatcagcgtcgccgtgccggtgggcgatcagaccgcggagcggttgcgc
gccaggctgatcgagcggatcaataacttgcgggtgggacacagcctggaccccaaggcg
gactacggcccgctggtcaccggggcggcgctggcgcgggtgcgcgactacatcggccag
ggtgtggccgccggtgccgagctggtcgttgacggccgcgaccgcgccagcgacgacctg
acctttgggctgcctgaaggcgatgcgaacctggagggcggcttcttcatcgggccgacc
ctgttcgaccatgtcgctgcccacatgtcgatctacaccgacgaaatcttcgggccggtg
ttgtgcatggttcgcgcccgcgactacgaagaggcgttgcggctgccgtcggagcacgaa
tacggcaacggggtggcgatcttcacccgcgacggcgacgcggcccgcgacttcgtctcc
cgggtgcaggtgggcatggtcggcgtcaacgtgccgatcccggtgccggtggcctaccac
actttcggcggctggaagcgctccggcttcggcgacctcaaccagcacggcccggcggca
atccagttctacaccaaggtcaagaccgtcacgtcgcgatggccgtcaggcatcaaggac
ggtgccgaattcgtcatccccacaatgagttag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (2)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (2)   
   Pfam (2)   
All databases (33)   

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