KEGG   Mycobacterium tuberculosis H37Rv: Rv2868c
Entry
Rv2868c           CDS       T00015                                 
Symbol
gcpE
Name
(RefSeq) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)
  KO
K03526  (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3]
Organism
mtu  Mycobacterium tuberculosis H37Rv
Pathway
mtu00900  Terpenoid backbone biosynthesis
mtu01100  Metabolic pathways
mtu01110  Biosynthesis of secondary metabolites
Module
mtu_M00096  C5 isoprenoid biosynthesis, non-mevalonate pathway
Brite
KEGG Orthology (KO) [BR:mtu00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    Rv2868c (gcpE)
Enzymes [BR:mtu01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.7  With an iron-sulfur protein as acceptor
    1.17.7.1  (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin)
     Rv2868c (gcpE)
    1.17.7.3  (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin)
     Rv2868c (gcpE)
SSDB
Motif
Pfam: GcpE MR_MLE_C zf-RING_7
Other DBs
NCBI-GeneID: 887463
NCBI-ProteinID: NP_217384
TubercuList: Rv2868c
UniProt: P9WKG3
Position
complement(3179368..3180531)
AA seq 387 aa
MTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAEL
TAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGN
IKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEE
HGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSR
GIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAG
LDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIE
EAMRLAAEMGEQDPGATPSGSPIVTVS
NT seq 1164 nt   +upstreamnt  +downstreamnt
gtgactgtaggcttgggcatgccgcagcccccggcacccacgctcgctccccggcgcgcc
acccgtcagctgatggtcggcaacgtcggcgtgggcagtgaccatccggtctcggtgcaa
tcgatgtgcaccaccaaaacccacgacgtcaactcgacattgcaacaaatcgccgagctg
accgcggccggatgcgacatcgtgcgggtggcctgcccgcgccaggaggacgccgacgcg
ctggccgagatcgcccggcacagccagatcccggtagtcgcggacatacatttccagccg
cgctacatattcgccgccatcgacgctggatgtgccgcggtgcgggtcaacccgggcaac
atcaaggagtttgacggccgggtgggtgaggtcgccaaggcggcgggtgcggccgggatc
ccgatccgaatcggtgtcaacgccggttcgctggacaaacggttcatggagaagtatggc
aaagccacgcccgaggcgctggttgagtcggcgctgtgggaggcttcgcttttcgaggag
catggcttcggtgacatcaagatcagcgtcaagcacaacgacccggtggtgatggtcgcc
gcctacgagctgcttgctgcacggtgcgactacccactgcacctcggtgtcaccgaggcc
ggccctgctttccagggcaccatcaagtccgcggttgccttcggcgcgttgctgtcgcgg
ggcataggcgacaccatccgggtgtcgttgtcggccccgccggtcgaggaagtcaaggtg
ggcaatcaggttctcgagtcgttgaacctgcggccgcgttcgctcgagatcgtgtcttgc
ccgtcgtgcggtcgcgcgcaagtcgacgtctacaccctggccaacgaggtaaccgccggc
ctggatggtctcgatgtgccgttgcgggtggccgtgatggggtgtgtcgtcaatggtccg
ggtgaagcacgtgaggccgacctgggcgtggcgtccggcaacggcaaaggtcagatcttt
gtacggggcgaagtgatcaagaccgtgcccgaagcacagatcgtcgagacgctgatcgag
gaggcgatgcggctggccgccgaaatgggcgagcaagatccgggcgcgacaccgagcggt
tcgcctattgtgaccgtaagctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   TUBERCULIST (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (35)   

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