KEGG   Mycobacterium ulcerans: MUL_1968
Entry
MUL_1968          CDS       T00435                                 
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase (large subunit) LeuC
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
mul  Mycobacterium ulcerans
Pathway
mul00290  Valine, leucine and isoleucine biosynthesis
mul00660  C5-Branched dibasic acid metabolism
mul01100  Metabolic pathways
mul01110  Biosynthesis of secondary metabolites
mul01210  2-Oxocarboxylic acid metabolism
mul01230  Biosynthesis of amino acids
Module
mul_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:mul00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    MUL_1968 (leuC)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    MUL_1968 (leuC)
Enzymes [BR:mul01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     MUL_1968 (leuC)
    4.2.1.35  (R)-2-methylmalate dehydratase
     MUL_1968 (leuC)
SSDB
Motif
Pfam: Aconitase AcnX
Other DBs
NCBI-ProteinID: ABL04415
Pasteur: MUL_1968
UniProt: A0PPZ6
Position
2175142..2176563
AA seq 473 aa
MALQTREARTLAEKVWDDHVVVSGRNEAPDLIYIDLHQVHEVTSPQAFDGLRLAGRPVRR
PDLTIATEDHNVPTVDIDKPIADPVSRTQVETLRRNCAEFGIRLHPMGDVEQGIVHVVGP
QLGLTQPGMTIVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLWPFKTMAVNVDGQ
LPAGVSAKDIILALIAKIGTGGGQGHVIEYQGSAIESLSMEGRMTICNMSIEAGARAGMV
APDETTYEYLRNRPHAPTGAQWDAALGYWQQLRTDPGAVFDTEVHLDAAELSPFVTWGTN
PGQGVPLCATVPDPELIGDDGERQAAEKALAYMDLEPGKAMRDIAVDAVFVGSCTNGRIE
DLRVVAEVLRGRKVAPGVRMLIVPGSMRVRAQAEKEGLGEVFTVAGAEWRQAGCSMCLGM
NPDQLAPGERCAATSNRNFEGRQGKGGRTHLVSPAVAAATAVRGTLSAPADLN
NT seq 1422 nt   +upstreamnt  +downstreamnt
atggcactgcagacgcgcgaggcgcgcacgctggctgagaaggtctgggacgaccacgtc
gtggtgtccggtcggaacgaggctcccgacctgatctacatcgatctgcatcaggtgcat
gaggtcaccagcccgcaggcattcgatggtctgcgcctggccggccgcccggtgcgacgg
cccgatctgaccatcgccaccgaggatcacaatgtgccgaccgtcgatatcgataagccg
atcgccgacccggtgtctcggacccaggtggagacattgcggcgtaattgcgcggaattc
ggcatccggctgcaccccatgggtgatgtcgagcagggcatcgtgcacgtcgtgggacct
cagttgggcctcactcagccgggaatgaccatcgtctgtggtgacagccacacttcgacc
catggcgcgttcggtgccttggcgatgggcatcggcacttccgaagtcgagcatgtgctc
gcaacacagacgctgccgttgtggccgttcaagacgatggcggtcaatgtggatgggcaa
ctacccgcaggagtgtcggccaaggacatcatccttgcgctgatcgccaagatcggcacc
ggcggtgggcaggggcacgtcatcgaataccagggcagcgccattgaatcgctgtccatg
gaaggccggatgacgatctgcaacatgagcattgaggccggcgcccgagccgggatggtg
gcgccggacgagaccacttacgagtacttgcgaaaccggccacacgccccaaccggtgcc
cagtgggatgccgcgcttgggtactggcaacaactgcggaccgatcctggcgccgtcttc
gacaccgaggtccatctcgacgccgccgagctgagcccctttgttacgtggggaaccaat
cccggccagggcgtgccgctttgcgccacggtgcccgatcccgagctcatcggcgatgac
ggcgagcgccaggccgccgagaaagcattggcgtacatggaccttgagccaggaaaagcc
atgcgcgatatcgcggtcgatgccgtgttcgtcgggtcgtgcaccaacggccggatcgag
gatctgcgggtcgtggccgaagtgctgcgtggccgcaaggtcgccccaggggtgcgaatg
ctcatcgttcccggctccatgcgggtgcgtgcccaggccgagaaggagggcctgggtgag
gtcttcacggtcgcgggcgccgaatggcggcaggcgggatgctctatgtgcctagggatg
aaccccgatcagctcgcgccgggggagcgctgtgcggcgacgtccaaccgcaacttcgag
gggcgccagggcaagggcgggcggacacatttggtctcgccggcggtggccgccgcaacc
gcggttcgcggcaccctatccgcgcctgccgatttgaattga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (19)   
   KEGG COMPOUND (19)   
Chemical reaction (13)   
   KEGG ENZYME (2)   
   KEGG REACTION (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
   PASTEUR (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (2)   
   Pfam (2)   
All databases (51)   

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