KEGG   Maylandia zebra (zebra mbuna): 101468908
Entry
101468908         CDS       T02814                                 
Symbol
tsc2
Name
(RefSeq) tuberin isoform X1
  KO
K07207  tuberous sclerosis 2
Organism
mze  Maylandia zebra (zebra mbuna)
Pathway
mze04115  p53 signaling pathway
mze04140  Autophagy - animal
mze04150  mTOR signaling pathway
mze04218  Cellular senescence
mze04910  Insulin signaling pathway
mze05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:mze00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    101468908 (tsc2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101468908 (tsc2)
  09143 Cell growth and death
   04115 p53 signaling pathway
    101468908 (tsc2)
   04218 Cellular senescence
    101468908 (tsc2)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    101468908 (tsc2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    101468908 (tsc2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mze01009]
    101468908 (tsc2)
Protein phosphatases and associated proteins [BR:mze01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     101468908 (tsc2)
SSDB
Motif
Pfam: Tuberin DUF3384 Rap_GAP
Other DBs
NCBI-GeneID: 101468908
NCBI-ProteinID: XP_004539093
Position
LG6:complement(29115668..29148610)
AA seq 1899 aa
MNKQPSKESLKDKVKGIFGLGTQRPPNKQSDTKPSEFIITADIIKELHPDCGLSNRVRTM
NHICELAKMKKFEEHAVEAVWKNVEDMLTPEQPPEARHAVLQLLRAIIQGQGERLGPLRA
YFFKVIRDYQPCNEDLSDRLEVFKALTENGKDITYLEEDIARFVLLWMDIGLTSDFLHVL
VNLVKFNSCYLDQNVSIMVQKICLLCNRTTSSTDIEVALQVLDAVVCYNCLPSDSLTVFI
ITLCRTVNVKEFCESCWKLMRKVLGTHLGHSAIYTMCRIMEERVYMEDAPLLRGAVFFVG
MALWGAHRLPALKNTPTLVLPSFYKAMSCANEVVSYEIVLSITRLIKKYGKELQVVTWDI
LLGIIERLLQQIQTIGSAELKAIVYELLTTVEELYEQNGYHGSTEKFFSLVEKCADKRPD
ASVLTLISYRAQSIQPAKEGWIQSLHRLMEKFFRNETRSVIRIKVLHILSFVLSTNRQLY
EDELIEMVVIPQLSGIAEDRDLAVRKQATQLLVDLAEGCNTHHFTSLLDIIERVSSRSLV
CSGPLEVSERDPTAESPMEDVRTAILGLLEILQSKLYSLPASHASRVYELLISHLQLHYK
NKYCSTIASTIRLKVFDFFLMMRADSLHRLGVPNKDGVMRFSPYCYCDIGEPEKRVGEKK
PAGSTSPPAGSPAPPAAPPSSAASTRSAYLSYSPAFSVLLQCLKMETDWKVLKLVLDKLP
WMLQYKVLLLTSPCNLDQLCSTLCCMVTDRLISERLKKTPEGFSRTDVQLAVIPVLTAIT
SYHNYLEQSRQRELVQCLETGLIYRCAKQCVVALTMCTVEMPDIMIKLLPALIVKLTHIS
ATVAMASPMLEFLSTLVRLPHLYANFVAEQYVSVFAISLPYTNPSKFNQYIVSLAHHVIA
MWFIRCRLPFRKDFVQYITKGLRSNALLPFDDSHEQSPFRARSTSLNERPKSLRAAKVAK
AAAAVANSSSSPVKELRDLSAMDAFRSRSISVSEHAVRRMHTSTTTCSLGSADENAVTQA
DEGLKTVHLELTETCLDMMARYVFSNFSALPKRSPIAEFLLAGGRSMTWLVGNKLVTITT
SGGVRTQALLGLDMADRLGGGGGELTRSDPSLHTRMTKEAPAKLESQSSQQHNRAARIRV
RSMSGGHALRAGPAQSLSPLVSPSEGELTAPLSPSSGPALDSLGPSSSTSATPSVPPTLK
DNPTLAEFAPMLTQGWAEIFIRRPSGNTSWLMCLENPPSPFSSELGNMPLQELSSVLMAM
EGVKEPPTQTASAPASTAVPAPAPVSEPLTQTHSSVGGKANLIQRSNTVGGSLCSLGMGT
APPGPPAPGRLHRSISWADSVVVLEEGSGIATANTPPEWLGSAEFEPMLSDPIFIAADKF
TKTPPETLSRSSSTSSQDDEKSTLEEVSEGAIPIDQPPFGPSTPGSQGPDLPFQTHTQSQ
GHGLNKSSSSPELQTLPEAFAKAAMESESAMVDTSRPRAPSDGMPQPQQPQFAKEKVEGN
TGVDTNVAGGPSPAGEGQAVSSSQSGGAGMRLSFPPAPVQSAPISPSGGHRPRGHTISVS
APSSRRERRAERDAYHSRPGPSNTEKISGLSPSFVFLQLYHSPFFGNEANKPLLLPKTQV
IDRAVKVLDQMPPYDTHKIGVVFVGAGQVNNEVAILSNEYGSNRYASFLTGLGKLIHLKD
CDPDQIFLGGLDQYGDDGEFTYCWHDDIMQAIFHIATLMPNRESDKGCCNKKRHIGNDFV
MVVYNDSGEEYKLGTIKGQFNFVEVIIKPLDYECNLVTLQCRKDLEGLVDTTVAKIVSDR
NLPLLVRQMALHANMASLVHQYRANPSDAYASKWLARLRHIKRIRTRAQEAIQSRSTPGI
SLTQGQSKPLSQSSAPTNVEATGQRKRLVSTVDDFTDFV
NT seq 5700 nt   +upstreamnt  +downstreamnt
atgaataaacaaccaagcaaggagagtctcaaggacaaggtgaaggggatctttgggctc
ggtacacagcgtcctccgaacaaacagagtgacactaaaccctccgagtttatcattacg
gctgacatcatcaaggagctccacccagattgcggtctgagcaaccgtgttcgcactatg
aaccacatctgtgagcttgccaaaatgaaaaagtttgaggagcatgcagtggaggctgta
tggaaaaatgtggaagacatgctgactccagagcagccaccagaggccagacatgctgtc
ctgcagctgctcagggccattatacaggggcagggtgagcgactcggccctctgagagcc
tactttttcaaggtaatcagagactaccagccgtgcaatgaagacctttctgacagactg
gaggtgtttaaggctttaacagagaatggaaaggatatcacatacctggaagaggacata
gcacgctttgtcctcctgtggatggatataggccttacatctgactttctccatgttctt
gttaatctggtgaaattcaatagctgctacttggaccaaaatgtttccatcatggtccag
aaaatttgcctgctgtgcaacagaacgacgtcttcgactgatattgaggtggctctgcaa
gtgctcgatgcagttgtgtgttacaactgcctgccctccgactctttaaccgttttcata
atcacactctgccgtacggtcaacgtcaaagagttttgcgagtcctgttggaagttaatg
agaaaggttttggggactcacctcggccatagtgcaatttacaccatgtgtcgcattatg
gaggaaagggtgtatatggaggatgcaccgttgttaagaggagcagttttctttgttgga
atggcgctttggggcgcacacagactgcctgcactcaaaaatacaccgacgcttgttctg
ccatctttctacaaggccatgtcatgtgccaacgaggtggtctcctacgaaattgttctt
tcaataacaagactcatcaaaaagtacggtaaagagctacaagtggtcacatgggacatc
ctactcggcatcatagagcgactgttgcaacagattcagacaataggcagtgcggaacta
aaggccattgtttatgaactgttgaccaccgtggaagagctttatgaacaaaacggttac
cacggctccactgagaagtttttcagcctggtggagaaatgtgctgataaaagaccagat
gcatcagtgctgacacttatctcctacagggctcagtctatccagcctgctaaagaaggc
tggattcagagccttcaccggctcatggagaaattcttcaggaacgagactcgcagtgtg
ataagaatcaaagtgcttcatatcctgtccttcgttctcagtaccaaccggcagctctat
gaggatgagttgattgaaatggtggtgattccccagctcagtgggattgctgaagaccgg
gacttggcagttagaaaacaggctactcagctattagtagacctcgctgagggctgcaac
acgcaccacttcaccagcctgctggacatcattgaacgggtgtctagccgctctctggtg
tgttcagggcccctagaggtttctgagagagaccccacagcagagtctcctatggaggac
gtcaggactgctattctgggcctgcttgaaatcctgcagagcaaactttacagtctgcca
gccagccatgcgagtcgtgtttatgagttgcttatcagccacctgcagcttcattacaag
aacaagtactgttcaactatcgcctccactattagactaaaggtgtttgacttcttcctc
atgatgcgtgcagactctcttcaccgtcttggggtcccaaacaaagatggtgtcatgaga
ttcagcccttattgctactgtgatataggggaaccagagaaacgtgttggtgaaaagaag
ccagcaggttcaacctctcctcctgctggcagccctgctcctcctgctgctcctcccagt
tcagcagcctcaacacgctcagcctacctttcctattcgcctgccttcagtgtcctcctg
cagtgcctcaagatggagacggattggaaggtgctgaagctggttcttgacaagctgcca
tggatgctgcagtacaaagtgttgctgctcacatcaccatgcaacttagatcagctgtgt
tctacactctgctgcatggtgacagatcgtctcatctcagagcgattgaaaaagactcca
gaggggttttctcgcacagatgttcagctggcagtgattcccgttcttacagcaattacc
tcctaccacaactacttggagcagtcaagacagagagaactggttcagtgcctcgagact
gggctcatttaccgctgtgccaagcaatgtgtggtggcccttacaatgtgcacggtggag
atgcctgatatcatgatcaagcttcttcctgctcttatcgtcaagctcactcacatctct
gctactgttgccatggcatctcctatgctcgagtttctctccaccctcgtgcgccttccc
catctgtatgccaactttgtagctgagcagtatgtcagcgtgtttgccatctcactacct
tacactaacccctcaaagttcaaccagtacattgtgtccctggcccaccatgtgattgcc
atgtggttcatacgctgcagactacccttccgcaaggactttgttcagtatatcacaaag
ggtttgcgttccaacgcccttctgccattcgatgacagtcatgagcagagtccgtttcgt
gcccgaagcaccagcctcaatgagagacccaagagcttgcgggcagcaaaagtggcaaag
gcagcagcagcggtagccaatagcagcagctctccagttaaagagctgagggacctttca
gccatggacgctttccgctcccgcagcatcagcgtctccgaacatgcggtccgcaggatg
cacacctcaaccaccacatgcagtctgggctctgccgatgaaaatgcagtaactcaggcc
gacgaggggctgaaaactgtccacctagagctcacagagacttgtcttgacatgatggcc
cgatatgtattttccaacttctctgcacttcccaagaggtctcccatcgcagagttcctg
ttagcaggaggccgcagtatgacctggttggtgggcaacaagttggtcaccataacaacc
agcggaggggtcagaacacaagcgctgctgggcctggacatggctgatcgcctgggagga
ggaggaggggaattgaccaggtcagacccatcactacacacccgaatgaccaaagaggct
ccagccaaattggagtcacagtcaagccagcagcacaacagagctgcacgcatacgagtt
cgctccatgtcaggtggtcatgctctacgtgccggtccagctcagagtctcagtcctctg
gtgtctccctctgagggtgagttgactgctccactctctccctcctctggtcctgctctg
gatagtttaggtccatcctcttccacctctgccactccatctgtgcctcctactctgaaa
gacaaccccaccttggctgaatttgccccaatgctcacacaaggctgggcagagatcttc
atacgcagaccgtcaggtaacacaagctggctaatgtgtttggagaacccacctagccct
ttctcatctgagcttggcaacatgccgctgcaagagctctccagtgttctgatggcaatg
gagggagtgaaggaacctcccactcagacagccagtgctcctgctagcacagctgtccct
gctccagctcctgtctctgagcccctaacccaaacacacagcagtgttggaggaaaggca
aacctgattcagcgctccaacacagtgggtggctctctctgctctctgggtatgggcact
gcccccccaggcccaccagcccctggcaggttgcacaggagcatttcctgggcagactct
gtcgtggtgctggaggagggatcaggaattgctacagcaaacacgccgcctgaatggctg
gggagtgcagagtttgagccaatgttgtctgatccaatcttcatagctgctgataagttt
acaaagactcctcctgaaacactcagcaggtcctcctccacctcaagtcaggatgatgaa
aagtcaaccctggaagaagtaagtgagggagcaattccaatcgatcagcccccttttgga
ccatccactccaggaagccaggggcctgaccttcccttccagacacacactcagtcccag
ggtcatggactcaacaagtccagctcctctcctgagctccagacattacctgaagctttt
gccaaggctgctatggagtcagaaagtgcgatggttgacacgtcacggcctagagcaccc
tcagacggcatgcctcaaccccagcagccccagtttgcgaaagaaaaggtagagggaaac
actggagtggacactaatgtagcgggaggtccaagcccagcaggtgaaggccaagctgta
tcgtcatctcagagtggaggagcggggatgaggttgtcttttccaccagcaccagtacaa
tctgcacccatctcccccagtggaggccaccggcccagaggtcacacaatctcagtctca
gccccctcctccaggagggagaggcgggcggagagggacgcttaccacagtcgacctggt
cccagcaacactgagaaaatctctggactgagccccagctttgtgtttctgcagctctac
cactctcctttctttgggaatgaagccaacaagccacttctgctgcccaaaactcaggtg
attgaccgtgcagtaaaggttctggaccaaatgcccccttatgacacccataaaattggg
gtggtgtttgtaggagctggtcaggttaacaatgaagtcgccatcttgtcgaacgagtac
ggttcgaaccgctacgcctctttcctcacaggtcttggcaaattaatccatctgaaagac
tgcgatccagaccagatttttcttggagggcttgaccagtatggagatgatggagagttc
acctactgctggcatgacgacatcatgcaggctatctttcacatagccacactgatgcca
aacagggagagcgacaagggttgctgcaacaaaaagcgacacattggcaacgattttgtc
atggtggtgtacaatgactctggagaggagtacaaactgggcacaattaagggtcagttt
aattttgtcgaagtcattataaaaccactggattatgaatgtaacctcgttaccctccag
tgccgcaaagacctcgagggattagtagacacaacggtggcaaaaattgtttcagatcga
aaccttcccctgttagtcaggcagatggctctgcatgcaaatatggcctcattggtgcac
cagtacagagctaacccctctgacgcatacgcctctaagtggctagcaaggttacgacac
atcaagaggatcaggaccagggctcaagaagccatccagtctcgctcaactcccgggatt
tcactgacccaagggcagagcaaacctttgtcacagagcagtgctccaacaaatgtggaa
gccaccggacaacgaaaaagactggtgtccactgtagacgatttcacagattttgtttaa

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (40)   
   KEGG ORTHOLOGY (1)   
   RefGene (36)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (11)   
   RefSeq(nuc) (5)   
   GenBank (3)   
   EMBL (3)   
Protein domain (3)   
   Pfam (3)   
All databases (68)   

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