KEGG   Necator americanus (New World hookworm): NECAME_06519
Entry
NECAME_06519      CDS       T04867                                 
Name
(RefSeq) methylmalonate-semialdehyde dehydrogenase
  KO
K00140  malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
Organism
nai  Necator americanus (New World hookworm)
Pathway
nai00280  Valine, leucine and isoleucine degradation
nai00410  beta-Alanine metabolism
nai00562  Inositol phosphate metabolism
nai00640  Propanoate metabolism
nai01100  Metabolic pathways
nai01200  Carbon metabolism
Brite
KEGG Orthology (KO) [BR:nai00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    NECAME_06519
   00562 Inositol phosphate metabolism
    NECAME_06519
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    NECAME_06519
  09106 Metabolism of other amino acids
   00410 beta-Alanine metabolism
    NECAME_06519
Enzymes [BR:nai01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.18  malonate-semialdehyde dehydrogenase (acetylating)
     NECAME_06519
    1.2.1.27  methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
     NECAME_06519
SSDB
Motif
Pfam: Aldedh LuxC YCII DUF5421
Other DBs
NCBI-GeneID: 25346551
NCBI-ProteinID: XP_013307451
UniProt: W2TUB1
Position
Unknown
AA seq 455 aa
MEAATESCKKAFASWKNTSPLTRQQTLFRLQSLIKRDIKKIAENITLEQGKTLPDAEGDV
NRGLQVVEHACSVPSLMLGETLPNVSRDMDTYSFRIPLGVTAGICPFNFPAMIPLWMFPL
AIATGNTMLLKPSEQDPGACMMLVELAKEAGIPDGCVNVIHGQHDAVNFICDHPAIRAIS
FVGADTAGKHIYERGAQNGKRVQSNMGAKNHGVIMADCNKEQTLNQLTAAAFGAAGQRCM
ALTTAILVGEARAWLPEIVEKAKKLHVNAGWKPDTDVGPLISKAAKNRVISLIQGAKKEG
ANVALDGSDIVVPGFENGNFVGPSVIAGVKPNMTCYKEEIFGPVLVIMEAENLNEATEII
NQNPYGNGTAIFTSNGATARKFTNEVDVGQVGVNVPIPVPLPMFSFTGSRGSFLGDMNFY
GKAGINFYSQWKTVTQYWNESLTELKPQMSFPQLK
NT seq 1368 nt   +upstreamnt  +downstreamnt
atggaagcagctactgaatcgtgtaagaaagcttttgcttcgtggaagaatacatcacca
ttgactcgtcagcaaacgcttttccgccttcaaagcttaattaaacgcgacataaagaaa
attgctgaaaacatcactctagagcagggaaagactttgcccgacgccgaaggagatgtc
aatcgaggtcttcaggttgtggaacatgcctgctccgtcccatcgttgatgcttggagaa
acgcttccgaatgtttcgcgggatatggatacctattcttttcgcatccctctaggagtg
acagctggcatttgtcctttcaacttccctgctatgattccactgtggatgttcccgtta
gccattgctaccggcaatactatgcttctcaaaccctcagaacaagatcctggggcgtgc
atgatgcttgttgagctagccaaggaggctggaatacctgatggttgcgttaacgttatt
cacggacaacatgatgcagtaaatttcatatgcgatcatcctgctattcgtgccatatct
ttcgttggggctgacacagctggaaaacacatttacgaaagaggtgctcaaaacggaaag
cgtgtgcagtctaatatgggagcgaaaaatcatggagttataatggcggactgcaataag
gagcagaccctcaatcaattaaccgctgctgcatttggagccgctggtcagcgttgtatg
gctctaaccactgcgatactcgttggagaagcccgcgcctggcttccagaaattgtggaa
aaggccaagaaactgcatgtgaacgcaggatggaagccagacacagacgttggtccgctg
atctcaaaagcagccaaaaatcgcgtaatcagtcttatccaaggagccaaaaaggaagga
gctaatgtcgctctagatggaagcgacattgtcgtacccggattcgaaaatggtaacttc
gttggtccgtctgtcattgctggagtaaagccaaacatgacctgttacaaggaagaaata
ttcggtcctgtattagtgattatggaagctgagaatttgaacgaagcaacagaaattatc
aaccagaatccatacggaaacggaacagcaattttcacttcaaatggtgctactgccaga
aagtttacaaacgaggtagatgtcggacaagtcggtgtcaatgtgccaatcccggtccct
cttccgatgttctcctttactggttcacgtggatcattccttggagatatgaatttctat
ggaaaggccggcatcaatttttactcacaatggaagacagttacacaatactggaacgaa
agcttaacagagttgaagcctcaaatgtctttccctcagcttaagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (2)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (55)   

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