KEGG   Nannospalax galili (Upper Galilee mountains blind mole rat): 103733801
Entry
103733801         CDS       T03372                                 
Symbol
Ret
Name
(RefSeq) ret proto-oncogene
  KO
K05126  proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
Organism
ngi  Nannospalax galili (Upper Galilee mountains blind mole rat)
Pathway
ngi04010  MAPK signaling pathway
ngi04020  Calcium signaling pathway
ngi04151  PI3K-Akt signaling pathway
ngi05200  Pathways in cancer
ngi05216  Thyroid cancer
ngi05223  Non-small cell lung cancer
ngi05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ngi00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103733801 (Ret)
   04020 Calcium signaling pathway
    103733801 (Ret)
   04151 PI3K-Akt signaling pathway
    103733801 (Ret)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103733801 (Ret)
   05230 Central carbon metabolism in cancer
    103733801 (Ret)
  09162 Cancer: specific types
   05216 Thyroid cancer
    103733801 (Ret)
   05223 Non-small cell lung cancer
    103733801 (Ret)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ngi01001]
    103733801 (Ret)
Enzymes [BR:ngi01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     103733801 (Ret)
Protein kinases [BR:ngi01001]
 Receptor tyrosine kinases (RTK)
  RET family
   103733801 (Ret)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr RET_CLD4 RET_CLD1 RET_CLD3 Pkinase Cadherin RIO1 Pkinase_fungal Haspin_kinase ABC1
Other DBs
NCBI-GeneID: 103733801
NCBI-ProteinID: XP_008830906
UniProt: A0A8C6W6L3
Position
Un
AA seq 1114 aa
MAKATSGAAGLGLKLFLLLPLLGEAPLGLYFSRDAYRERLYVDQPAGTPLLYVHALRDAP
GEVPSFRLGQYLYGAYRTRLHENDWIRIQEDTGLLYLNQSLNHSSWEQLSIRNGGFPLLT
VFLQVFLGSTALREGECQWPGCARVYFSFINGSFPACSSLQSQDLCLPESGLSFRIRENR
PPGTFHQFHLLPVQFLCPNISVAYRLLEGESLPFYCDPDSLEVSTCWALDRELQEKYVLE
AECIVHNGVSEEKVTVSLPVTVYDEDDSAPTFSRGVDTASAVVEFKRKEGTVVATLHVFD
ADVVPASGELVRRYTSTLLSGDSWAQQTFRVEHSPNEILAQANSSFVRATMHDYKLILNR
SLPISESRVLQLVVLVNDSDFQGPGTGVLLLHFNVSVLPVSLHLPGAYSFSVNRRARRYA
QIGKVCVENCQEFSGIHIQYKLQPSGTNCSALGVVTSAEDTSGTLFVNDTEALQRPECAE
LQYTVVATDRQTRRQAQASLLVTVEGTYIAEEVGCPESCAVSKRRAECEECGGLGSLTGR
CEWRQGDGKGITRNFSTCSPSTRTCPDGHCDAVENRDINICPQDCLRGSIVGGHEPGERR
GIKAGYGICNCFPEEKKCFCEPEDSQGPLCDELCRTVISAAVLFSFIVSVLLSTFCIHRY
HKHAHKPPIASAEMTFCRPAQGFPISYSSSGTRRPSLDSMENQVSVDAFKIPEDPKWEFP
RKNLVLGKTLGEGEFGKVVKATAFRLKGRAGYTTVAVKMLKENASPSELRDLLSEFNLLK
QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRDSRKIGPGYVGGGGSRNSSSLDH
PDERVLTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVY
EEDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERL
FNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKSRDYLDLAA
STPSDSLLYDDGLSEEETPLVDCNNAPLPRSLPSTWIENKLYGMSDPNWPGESPVPLTRA
DGTSTGFPRYANDSVYANWMVSPSAAKLMDTFDS
NT seq 3345 nt   +upstreamnt  +downstreamnt
atggcgaaggcgacgtccggcgccgcagggctggggctgaagctgttcttgctgctgcca
ctgctaggcgaagcccctctgggcctctacttctcaagagatgcttaccgggagaggcta
tatgtggaccagccagccggcacacctctgctctatgtccatgccctacgagacgcccct
ggagaagtacccagcttccgcctgggccagtacctctatggtgcctatcgcacacgacta
catgagaatgattggatccgcatccaggaagacactggcctcctctacctcaaccagagc
ctgaaccacagctcctgggaacagctcagcatccgcaatggtggcttccccttgcttaca
gtcttcctccaggtcttcctggggtccacagctctgcgagaaggcgagtgccagtggcca
ggctgtgcccgtgtgtacttctccttcatcaatggctccttcccagcttgcagctctctt
caatcccaggatctctgcctcccagagtcaggcctgtccttccgcatcagggagaacagg
cccccaggcactttccaccagtttcaccttttgcccgtgcagttcctttgccccaacatc
agtgtggcttatagactattagaaggtgagagtctgcccttctattgcgacccagacagc
ctggaggtgagcacttgctgggccctggaccgtgagcttcaagaaaagtatgtgctggag
gccgagtgcatagttcacaatggtgtcagtgaggagaaggtgacagtgtcccttcctgtg
acagtgtatgatgaggacgactcagcgcccaccttctctaggggtgtggacactgccagt
gctgtggtggaatttaagcggaaggagggtactgtggtggccactctgcatgtgttcgat
gcggatgtggtacctgcatccggggagctggtgagacggtacacaagcacactactctca
ggggactcctgggcccagcagaccttccgggtggagcactcacccaacgagatcttggcc
caggccaacagcagcttcgtgcgggcaaccatgcatgattacaagctgattctcaaccgg
agcctgcccatctcagagagcagagtcctgcagctggtggtcctggtcaatgactcagac
ttccaggggcctggaacaggtgtcctcctcctccatttcaatgtgtctgtgttgcctgtt
agcctgcatctgcccggtgcctactccttctctgtgaacaggagggcccgccgttatgca
cagattgggaaagtctgtgtggaaaactgccaggaattcagcggcatccacatccagtac
aagctgcaaccctccggcaccaactgcagtgctctaggtgtggtcacctcagctgaggac
acctcagggaccctgtttgtaaacgacacagaagccctgcagcgacctgaatgtgccgag
ctccagtacacagtggtggccactgaccggcagacccgcaggcaggcccaggcctcgctg
ctcgtcactgtagaggggacgtacattgctgaggaagtgggctgccccgagtcctgtgca
gtcagcaagagacgagctgaatgtgaggagtgcggtggcctgggctctctgactggcagg
tgcgagtggcgtcagggagacggcaaagggatcaccaggaacttctccacctgctccccc
agcaccaggacctgccctgatggccactgtgatgctgtggagaaccgggatatcaacatt
tgcccccaggactgcctccgtggcagcattgttgggggacatgaaccaggggagcgccgt
gggattaaagccggctatggcatctgcaactgcttcccagaggagaagaagtgcttctgt
gagcccgaggacagtcaaggcccgctgtgcgatgagctgtgtcgcacggtgatctcagca
gccgtcctcttctccttcatcgtctcggtcctgctgtccaccttctgcatccaccgctac
cacaagcatgcccacaagccacccattgcttcagcggagatgaccttctgccggcctgcc
cagggctttccaatcagctattcttcctccggcacccgccggccctcactggattccatg
gagaaccaggtttctgtggatgccttcaagattccggaagatccaaagtgggaatttcct
cggaagaacttggttcttgggaaaaccctgggagaaggcgagtttggaaaagtggtcaaa
gcaacagccttccgtctgaaaggcagagcagggtacaccacggtggctgtgaagatgctg
aaagaaaatgcctccccgagtgagttacgagacctgctgtctgagttcaacctgctgaag
caggtcaaccacccacatgtcatcaagttgtatggggcctgcagccaggatgggcctctc
ctcctcattgtggagtacgccaagtatggctccctacgaggttttctccgcgacagccgc
aagattgggccgggctacgtgggcggtggaggcagccgcaattccagctccctagatcac
ccagatgagcgggtgctgactatgggtgacctcatctccttcgcctggcagatctcaagg
ggcatgcagtacttggctgagatgaagctcgtacaccgggacttagcggctaggaacatc
ctggtggctgaggggcggaagatgaagatttctgattttggtttgtcccgagatgtttat
gaagaagattcttacgtgaagagaagcaagggccggattcctgtcaaatggatggcaatt
gagtccctttttgatcacatctacaccactcaaagtgatgtgtggtcctttggggtccta
ctgtgggagattgtgactctggggggcaacccctaccctggaattcctcctgaacgactc
ttcaaccttctgaagacgggccacaggatggagaggccagacaactgcagcgaagaaatg
taccgactgatgctgcaatgctggaagcaggaaccagacaagaggccagtattcgctgac
atcagcaaggacctggagaagatgatggtcaagagcagagactacttggacctggctgca
tccactccatctgattcactgctttatgatgatggcctctcggaagaggagacacccctg
gtggactgtaacaatgctcccctcccgcgctctctcccttccacatggattgaaaacaaa
ctctatggcatgtcagacccgaactggcctggagagagtcctgtaccactcacgagagcc
gatggcactagcactgggttcccacgatatgcaaatgatagtgtatatgctaactggatg
gtttcaccctcagcggcaaaattaatggacacatttgatagttaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (7)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (5)   
   RefSeq(nuc) (3)   
   GenBank (1)   
   EMBL (1)   
Protein domain (10)   
   Pfam (10)   
All databases (50)   

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