KEGG   Neisseria lactamica: NLA_4660
Entry
NLA_4660          CDS       T01368                                 
Symbol
murF
Name
(GenBank) UDP-MurNAc-pentapeptide synthetase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
nla  Neisseria lactamica
Pathway
nla00300  Lysine biosynthesis
nla00550  Peptidoglycan biosynthesis
nla01100  Metabolic pathways
nla01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:nla00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    NLA_4660 (murF)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    NLA_4660 (murF)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    NLA_4660 (murF)
Enzymes [BR:nla01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     NLA_4660 (murF)
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase
Other DBs
NCBI-ProteinID: CBN86706
UniProt: E4ZBH9
Position
444839..446197
AA seq 452 aa
MKPLDLNFICQALKLPMPSENKPVSRIVTDSRDIRAGDVFFALAGGRFDAHDFVEDVLAA
GAAAVVVSREDCASLKDALKVDDTLAALQTLAKAWRENVNPFVFGITGSVGKTTVKEMLA
AVLRRRFGNDAVLATAGNFNNHIGLPLTLLKLNEKHRYAVIEMGMNHFGELAVLTQIAKP
DAALANNAMRAHIGCGFDGVGDIAKAKSEIYQGLCSDGIALIPQEDANLAVFKTATLNLN
TRTFGIDSGDVHAENIVLKPLSCEFDLVCGNERAAVVLPVPGRHNVHNAAAAAALALAAG
LGLNDVAEGLKGFSNIKGRLNVKSGIKGATLIDDTYNANPDSMKAAIDVLARMPAPRIFV
MGDMGELGEDEAAAMHAEVGAYARDQGIEAAYFVGDNSVEAAETFGADGLWFAAKDPLIQ
VLRHDLPERATVLVKGSRFMQMEEVVEALEDK
NT seq 1359 nt   +upstreamnt  +downstreamnt
atgaaaccactggatctaaatttcatctgccaagccctcaagcttccgatgccgtctgaa
aacaaacccgtgtcgcgcatcgtcaccgacagccgcgacatccgcgcgggcgatgtgttt
ttcgcattggcgggcgggcggtttgacgcgcatgattttgttgaagacgtattggctgcg
ggtgcggcggcggttgtggtttcgcgcgaagattgcgcgtctttgaaagacgcgttgaaa
gtcgatgacacgcttgccgcattgcaaacgctggcaaaggcgtggcgtgaaaatgtgaat
ccgtttgtgttcggtattaccggttcggtcggcaagacgacggtaaaggaaatgctggct
gcggtattgcgccgccgtttcggcaatgatgctgtgttggcgacggcgggcaatttcaac
aaccacatcggattgccgcttactttgttgaaattaaacgaaaaacaccgctatgccgtg
attgaaatgggcatgaaccattttggcgaactggcggttttaacgcaaatcgccaaaccc
gatgccgccttggccaacaatgccatgcgcgcccatatcggctgcggttttgacggagtg
ggcgatattgccaaagcgaaaagcgagatttatcaaggcttatgttcagacggcattgcg
ctgattcctcaagaagatgccaatctggctgttttcaaaacggcaacgcttaatttgaat
acgcgcactttcggcatcgatagcggcgatgtccacgcggaaaatatcgtgctgaaacct
ttgtcgtgcgaatttgatttggtgtgcggaaacgaacgcgcagccgtggtgctgcctgtt
cccggccgccacaatgtccacaacgccgccgctgccgccgcgctggctttggctgcgggt
ttgggtttgaacgatgtggcggaaggtttgaaaggtttcagcaacatcaaaggccgtctg
aacgtcaaatccggcatcaagggcgcgaccctgattgatgatacctacaatgcgaatccc
gacagtatgaaagccgcgattgacgtgttggcgcgtatgcctgcgccgcgtattttcgtg
atgggcgatatgggcgaactgggcgaggacgaagcagccgccatgcacgccgaagtcggc
gcgtatgcccgcgaccaaggcatcgaagcggcttattttgtcggcgacaacagcgtcgaa
gcggcggaaacatttggcgcggacggtttgtggttcgccgccaaagacccgttgattcaa
gtgttgcgccacgatttgcccgaacgcgccaccgtgttggtgaaaggttcgcgctttatg
cagatggaagaagtggtcgaggcattggaggataagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (25)   

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