KEGG   Nomascus leucogenys (northern white-cheeked gibbon): 100594433
Entry
100594433         CDS       T03265                                 
Symbol
KMT2B
Name
(RefSeq) LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2B
  KO
K14959  [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354]
Organism
nle  Nomascus leucogenys (northern white-cheeked gibbon)
Pathway
nle00310  Lysine degradation
nle01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:nle00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    100594433 (KMT2B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:nle03000]
    100594433 (KMT2B)
   03036 Chromosome and associated proteins [BR:nle03036]
    100594433 (KMT2B)
Enzymes [BR:nle01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.354  [histone H3]-lysine4 N-trimethyltransferase
     100594433 (KMT2B)
Transcription factors [BR:nle03000]
 Eukaryotic type
  Zinc finger
   CXXC CpG-binding proteins
    100594433 (KMT2B)
Chromosome and associated proteins [BR:nle03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     100594433 (KMT2B)
   HMT complexes
    MLL3/MLL4 complex
     100594433 (KMT2B)
SSDB
Motif
Pfam: SET FYRC FYRN PHD zf-CXXC zf-HC5HC2H zf-HC5HC2H_2 Bromodomain PHD_4 CAF20
Other DBs
NCBI-GeneID: 100594433
NCBI-ProteinID: XP_030675976
Ensembl: ENSNLEG00000011306
Position
10:complement(41243341..41264243)
AA seq 2714 aa
MAAAAGGGSCPGPGSARGRFPGRPRGAGGGGGRGGRGNGAERVRVALRRGGGATGPGGAE
PGEDTALLRLLGLRRGLRRLRRLWAGPRVQRGRGRGRGRGWGPSRGCVPEEESSDGESDE
EEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARK
RGEEGTERMVQALTELLRRAQAPPAPRNRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVV
AEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGG
LPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDAPQRRVGSGQGGSPCWKKQEQK
LDDEGEEKKEEEKDEEEEEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPP
STSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRA
EREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVI
KTPRRFMDEDPPXPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKR
RSILREPTFRWTSLTRELPPPPPAPPPPPXPSPPPAPATSSRRPLLLRAPQFTPSEAHLK
IYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVATPVKAEVS
PHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPRQMPPLEKARIPGL
GSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRG
PVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRD
RQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLPSHHGKK
MRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKG
RTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAPPGPEEQDSLLQRKSARRCV
KQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEPEEQSRPRKPTLQPVLQLKARRR
LDKDALAPGPFASFPNGWTGKQKSPDGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGP
PMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGR
GSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGATPGKNWDVEWSG
DYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDEDYEILS
GLPDSVLYTCGPCAGAAQPRWREALSGALQGGLRQVLQGLLSSKVAGPLLLCTQCGLDGK
QLHPGPCSLQAVSQRFEDGHYKSVHSFMEDMVGILMRHSEEGETPERRAGGQMKGLLLKL
LESAFGWFDAHDPKYWRRSTRLPNGVLPNAVLPPSLDHVYAQWRQQEPETPESGQPPGDP
SAAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFE
ENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKV
FCQKHTDLLDGKEIVNPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDSL
GTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPAHLEAAEE
NQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPAPRSFS
GARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAP
RPPASRRASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDME
VVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTV
VSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGD
RARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPPQGLSVSPADPTR
TFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLP
PTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRV
STFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPG
EPAGEESPGPLQERSPLLPLPEVGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPDD
KENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEARGHARLRHLSFSGMSG
ARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQEEPPLNPHGAARAEVYLRKCTF
DMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVYR
SAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVDA
TMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNKL
PCNCGAKRCRRFLN
NT seq 8145 nt   +upstreamnt  +downstreamnt
atggcggcggcggcgggcggcggcagttgccccgggcctggctccgcgcggggccgcttc
ccgggccggccgcggggcgccggcgggggcgggggccgcggcggacggggcaacggggcc
gaaagagtgcgggtagctctgcggcgcggcggtggcgcgacggggccgggcggagccgag
cccggggaggacacggccctgctccgtttgctggggctccgccggggcctgcgccggctc
cgccgcctgtgggccggcccgcgggtccagcggggccggggccggggtcggggccggggc
tggggcccgagtcgaggctgcgtgccggaggaggagagcagtgacggggaatccgacgag
gaggagtttcagggttttcattcagatgaagatgtggcccccagttccctgcgctctgcg
ctgcgatcccagcgaggtcgagcgccccgaggtcggggtcgcaagcataagacgaccccc
cttcctcctcctcgcctagcagatgtggctcctacccccccaaagacccctgcccggaaa
cggggtgaggaaggcacagaacggatggtgcaggcactgactgaacttctccggcgggcc
caggcacccccagcaccccggaaccgggcatgtgagccctcaaccccccggcggtctcgg
ggacggcccccaggacggccagcaggcccctgcaggaggaagcagcaagcagtagtggtg
gcagaagcagctgtgacaatccccaaacctgagcccccacctcctgtggttccagtgaaa
caccagactggcagctggaagtgcaaggaggggcccggtccaggacctggaacccccagg
cgtggaggacagtcaagccgcggaggccgtggaggcaggggccgcggccgaggtggtggg
ctcccctttgtgatcaagtttgtttcaagggccaaaaaagtaaagatgggacaattgtcc
ttgggactcgaatcaggtcagggtcaaggtcaacatgaggaaagttggcaggatgccccc
caaagaagagttggatctggacagggagggagcccttgctggaaaaagcaggaacagaag
ctggatgacgagggagaagagaagaaagaagaagaaaaagacgaggaggaggaagaagag
aaggaagaaagagctgtagctgaggagatgatgccagccgcagaaaaggaagaggcaaag
ctgccaccaccgcctctgactcctccagccccttcacctcctccacccctcccaccccct
tcgacatctcctccacccccactctgccctccaccaccacccccagtgtccccaccacct
ctaccatcccctccaccacctcctgcccaagaggagcaggaagaatccccgcctcctgtg
gtcccagctacgtgctccaggaagaggggtcggcctcccctgactcccagccagcgggcg
gagcgggaagctgctcgggcagggccagagggcacctctcctcccactccaacccccagc
accgccacgggaggccctccggaagacagtcccaccgtggcccccaaaagcaccaccttc
ctgaagaatatccggcagtttattatgcctgtggtgagtgcccgctcctcccgtgtcatc
aagacaccccggcgatttatggatgaagaccccccanaacccccaaaggtggaggtctca
cctgtcctgcgacctcccatcaccacctccccacctgttccccaggagccagcaccagtc
ccctctccaccacgtgccccaactcctccatctaccccagtcccactccctgagaagaga
cggtccatcctaagggaacccacatttcgctggacctcactgacccgggagctgccccct
cctcccccagcccctccacctcccccgngcccctccccaccccctgctcctgccacctcc
tcccggaggcccctactccttcgggcccctcagtttaccccaagcgaagcccacctgaag
atctacgaatcggtgcttactcctcctcctcttggggctcctgaagcccctgagccagag
cctcctcctgccgatgactctccagctgagcctgagcctcgggcagtgggccgcaccaac
cacctcagcctgcctcgattcgcccctgtggtcgccactcctgttaaggccgaggtgtcc
cctcacggggctccagctctgagcaacgggccacagacacaggctcagctactgcagccc
ctgcaggccttgcaaacccagctcctgccccaggcgctaccgccaccacagccacagctg
cagccaccgccatcaccacggcagatgcctcccctggaaaaagcccggattccgggcctg
ggttccttgccgctgtctggggtggaggagaagatgttcagcctcctcaagagagccaaa
gtgcagctattcaagatcgaccagcagcagcagcagaaggtggcagcttccatgccgctg
agccctggagggcagatggaggaggtggccggggctgtcaagcagatctccgacagaggc
cctgtccgatctgaagatgagtcggtggaagctaagagagagcggccctcaggtcccgag
tcccctgtgcaaggtccccgcatcaaacatgtgtgccgtcatgctgctgtggccctgggt
caggcccgggccatggttcccgaagatgtccctcgcctcagtgccctccctctccgggat
cggcaggacctcgccacagaggatacatcatcggcgtccgagactgagagtgtcccgtca
cggtcccggcggggaaaggtggaggcagcaggccctgggggagaatcagagcccacaggg
tctggagggaccctggcccacacaccccggcgctcactgccctcccatcacggcaagaag
atgcggatggctcgatgtggacactgtcggggctgcttacgtgtgcaggactgtgggtca
tgtgtcaactgcctagacaagcccaagtttgggggccccaacaccaagaagcagtgctgt
gtataccggaagtgtgacaaaatagaggctcggaagatggaacgactggctaaaaaaggc
cggacgatagtgaagacgctgttgccctgggattccgatgaatctcctgaggcctcccct
ggtcctccaggcccacgccggggggcgggagctggggggccccgggaggaggtggtggcc
cccccagggcccgaggagcaggactccctcctgcagcgcaagtcagcccggcgctgcgtc
aaacagcgaccctcctatgatatcttcgaggattcggatgactcggagcccgggggcccc
cctgctcctcggcgtcggaccccccgagaaaatgagctgccactgccagaacctgaggag
cagagccggccccgcaaacccaccctgcagcctgtgttgcagctcaaggcccgaaggcgc
ctggacaaggatgctttggcccctggcccctttgcttcttttcccaatggctggactgga
aagcagaagtctcccgatggtgtgcaccgcgtccgtgtggattttaaggaggattgtgat
ttagagaacgtgtggctgatggggggcctgagcgtgctcacctctgtgccagggggcccc
ccgatggtgtgcttgctgtgtgccagcaaaggactccacgagctggtgttctgccaagtc
tgctgtgacccattccacccattctgcctggaggaggccgagcggcccctgccccagcat
cacgacacctggtgctgccgtcgctgcaaattctgccatgtctgtggacgcaaaggccgt
ggatccaagcacctcctggagtgcgagcgctgccgccatgcttaccacccggcctgtctg
gggcccagctatccaacgcgggccacgcgcaaacggcgccactggatctgttcagcctgt
gtgcgctgtaagagctgtggggcaactccaggcaagaactgggacgtcgagtggtctgga
gattacagcctctgccccaggtgcacccagctatatgagaaaggaaactactgcccgatc
tgcacacgctgctatgaagacaacgactatgagagcaagatgatgcagtgcgctcagtgt
gatcactgggtgcatgccaagtgcgaggggctctcagatgaagactatgagatcctttca
ggactgccagactcggtgctgtacacctgtggaccatgtgctggggcagcgcagcctcgc
tggcgagaggctctcagcggggccctccaggggggcctgcgccaggtgctccagggcctg
ctgagctccaaggtggcgggcccactgctgctctgcacccagtgtgggctggatgggaag
caactgcacccaggaccctgcagcctgcaagctgtgagtcagcgcttcgaggatggccac
tacaagtctgtgcacagcttcatggaggacatggtgggcatcctcatgcggcactcggag
gagggagagaccccggagcgccgggctggaggccagatgaaggggctcctgctgaagctg
ctagaatctgcgttcggctggttcgacgcccacgaccccaagtattggcgacggagtacc
cggctgccaaacggagtccttcccaatgcggtgttgcccccatccctggatcatgtctat
gcgcagtggagacagcaggaaccagagaccccagaatcagggcagcctccaggggatccg
tcagcagcattccagggcaaggatccggctgccttctcacacctggaggacccccgtcag
tgtgcactctgcctcaaatacggggatgcagactccaaggaggcagggcggctcttgtac
atcgggcagaacgagtggacacatgtcaactgtgccatctggtcggcggaagtcttcgag
gaaaacgacggctccctcaagaatgtgcatgctgctgtggcccgagggaggcagatgcgc
tgcgagctctgcctgaagcctggcgccacggtgggctgctgcctgtcctcctgcctcagc
aacttccacttcatgtgtgcccgggccagctactgcatcttccaggacgacaagaaagtc
ttctgccagaaacacactgatctcctggatggcaaggaaatcgtgaaccccgatggtttt
gatgttctccgccgagtctatgtggacttcgagggcatcaacttcaagcggaagttcttg
acggggcttgaacccgatgccatcaatgtgctcattggctccatccgcattgactccctg
ggtactctgtctgatctctcggactgcgagggacggctcttccccattggctaccaatgc
tcccgtctgtactggagcacagtggatgctcggaggcgctgctggtatcggtgccgaatt
ctggagtatcggccatgggggccgagggaagagccagctcacctggaggctgcagaggag
aaccagaccattgtgcacagccccgccccttcctcagagcccccaggtggtgaggacccc
ccactggacacagatgttcttgtccctggagctcctgagcgccactcgcccattcagaac
ctggaccctccactgcggccagattcaggcagcgcccctccagccccccgttctttctcg
ggggctcgaatcaaagtgcccaactactcgccatcccggaggcccttggggggtgtctcc
tttggccccctgccctcccctggaagtccatcttcactgacccaccacatccccacagtg
ggagacccggacttcccagctcccccgagacgttcccgtcgtcctagccctttggccccc
aggccgcctgcatcacggcgggcctcccctcctctaaaaacctcccctcagctcagggtg
ccccctcctacctcagtcgtcacagccctcacacctacctcaggggagctggctccccct
ggcccggccccatctccaccaccccctgaagacctgggcccagacttcgaggacatggag
gtggtgtcaggactgagtgctgctgacctggacttcgcggccagcctgctggggactgag
cccttccaggaagagattgtagccgctggggccatggggagcagccacgggggcccaggg
gacagctccgaggaggagtccagccccacctcccgctacatccacttcccggtgactgtg
gtgtccgcccctggtctggcccccagcgccacccctggagccccccgcattgaacagctg
gacggcgtggacgacggcactgacagcgaggccgaggcggtgcagcagcctcggggccag
ggcactcctccttcggggccaggagtagtccgggcaggggtccttggggccgcaggggac
agggcccggcctcctgaggacctgccatcggaaattgtggattttgtgttgaagaaccta
gggggacctggggatggaggtgctggccctagagaggagtcgcttcccccagcgcctccc
ctggctaatggcagccagcccccccaaggcctgtccgtcagcccagctgaccccacccgc
acatttgcctggctcccaggggccccgggggtccgggtgttaagccttggccctgcccct
gagccccccaaacctgccacatctaaaatcatccttgtcaacaagctggggcaagtattt
gtgaagatggctggggagggtgagcctgtcccacccccagtgaagcagccacctttgccc
cccaccatttcccccactgctcccacctcctggactctgcccccaggccccctcctcggc
gtgctgcctgtggtcggggtggtccgccctgccccacccccgccgccccctcccctgacg
ctggtgctcagcagtgggccagccagcccaccccgccaggccatccgcgtcaagagggtg
tccactttctccggccggtccccgccagcacctcccccatacaaagccccccggctggat
gaagatggagaggcctcagaggataccccccaggttccggggcttggcagtggcgggttt
agccgtgtgaggatgaaaacccccacagtgcgcggggtccttgacctggatcggcctggg
gagcccgctggggaagaaagtcctgggcctctccaggaacggtcccctttgctgccactt
ccggaagttggtcctccccaggtccccgatggtcccccagatctgctgcttgagtcccag
tggcaccactattcaggtgaggcttcgagctctgaggaagagcctccatccccagatgat
aaagagaaccaggccccgaaacggactggcccacatctgcgcttcgagatcagcagtgag
gatgggttcagcgtggaggcagagagcttggagggggcatggagaactctgatcgagaaa
gtgcaagaggcccgagggcatgcccgactcagacatctctcctttagtggaatgagtggg
gcaagactcctgggcatccaccacgatgctgtcatcttcctggctgagcagctccctgga
gcccagcgttgccagcactataagttccgttaccaccagcagggagagggccaggaagag
ccgcccctgaatccccacggggctgctcgggcagaggtctatctccggaagtgcaccttt
gacatgttcaacttcctggcctcccagcaccgagtgctccctgagggggccacctgtgac
gaggaggaggatgaggtgcagctcaggtcaaccagacgtgccaccagcctggagctgccc
atggccatgcgctttcgtcaccttaagaagacgtccaaagaagctgtgggtgtctacaga
tcagccatccacgggcgaggcctgttctgtaagcgcaacattgacgcgggggagatggtc
atcgagtactctggcatcgtcatccgctcggtgctgactgacaagcgggagaagttctac
gatgggaagggcatcgggtgctatatgttccgcatggatgactttgatgtagtggacgcc
acaatgcatggcaatgccgcccgcttcatcaaccactcctgtgagcccaactgcttctct
cgggtcatccacgtggaaggccagaaacacattgttatcttcgccctgcgccgcatcctg
cgtggtgaggagctcacctacgactacaagttccccatcgaggatgccagcaacaagctg
ccctgcaactgtggcgccaagcgctgccgtcggttccttaactga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (127)   
   KEGG ORTHOLOGY (1)   
   RefGene (122)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (10)   
   Pfam (10)   
All databases (156)   

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