KEGG   Ornithorhynchus anatinus (platypus): 100074240
Entry
100074240         CDS       T01045                                 
Symbol
FGFR1
Name
(RefSeq) fibroblast growth factor receptor 1 isoform X1
  KO
K04362  fibroblast growth factor receptor 1 [EC:2.7.10.1]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa04010  MAPK signaling pathway
oaa04014  Ras signaling pathway
oaa04015  Rap1 signaling pathway
oaa04020  Calcium signaling pathway
oaa04151  PI3K-Akt signaling pathway
oaa04520  Adherens junction
oaa04550  Signaling pathways regulating pluripotency of stem cells
oaa04714  Thermogenesis
oaa04810  Regulation of actin cytoskeleton
oaa04928  Parathyroid hormone synthesis, secretion and action
oaa05200  Pathways in cancer
oaa05205  Proteoglycans in cancer
oaa05215  Prostate cancer
oaa05218  Melanoma
oaa05224  Breast cancer
oaa05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100074240 (FGFR1)
   04014 Ras signaling pathway
    100074240 (FGFR1)
   04015 Rap1 signaling pathway
    100074240 (FGFR1)
   04020 Calcium signaling pathway
    100074240 (FGFR1)
   04151 PI3K-Akt signaling pathway
    100074240 (FGFR1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    100074240 (FGFR1)
   04550 Signaling pathways regulating pluripotency of stem cells
    100074240 (FGFR1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100074240 (FGFR1)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    100074240 (FGFR1)
  09159 Environmental adaptation
   04714 Thermogenesis
    100074240 (FGFR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100074240 (FGFR1)
   05205 Proteoglycans in cancer
    100074240 (FGFR1)
   05230 Central carbon metabolism in cancer
    100074240 (FGFR1)
  09162 Cancer: specific types
   05218 Melanoma
    100074240 (FGFR1)
   05215 Prostate cancer
    100074240 (FGFR1)
   05224 Breast cancer
    100074240 (FGFR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oaa01001]
    100074240 (FGFR1)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:oaa04090]
    100074240 (FGFR1)
   00536 Glycosaminoglycan binding proteins [BR:oaa00536]
    100074240 (FGFR1)
Enzymes [BR:oaa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100074240 (FGFR1)
Protein kinases [BR:oaa01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   100074240 (FGFR1)
CD molecules [BR:oaa04090]
 Proteins
  100074240 (FGFR1)
Glycosaminoglycan binding proteins [BR:oaa00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100074240 (FGFR1)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set ig Ig_3 Ig_2 V-set C2-set_2 ABC1 V-set_CD47 Pkinase_fungal DUF1615
Other DBs
NCBI-GeneID: 100074240
NCBI-ProteinID: XP_028922250
Ensembl: ENSOANG00000003252
Position
5:complement(38085625..38162379)
AA seq 822 aa
MWSWKCLLFWAVLVTATLCPARAAPTLPEHALPWGAPVEVESSLAHPGDLLQLRCRLRDD
VQSINWLRDGVQLAESNRTRITGEEVEVRDAVPSDSGLYACVTNSPSGSDITYFSVNVSD
ALPSAEDDDDDDDSSSEEKETDNTKPNRTPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPS
SGTPSPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENKYGSIN
HTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFVCKVYSDPQPHIQWLKHIEVNGSKI
GPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGISHHSAWLTVLE
ALEERPAVMTSPLYLEIIIYCTGAFLISCMVGTVIVYKMKSGTKKSDFHSQMAVHKLAKS
IPLRRQVTVSADSSTSMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVL
GKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGK
HKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHAPEEQLSSKDL
VSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNG
RLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMD
KPSNCTNDLYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSVPLDQYSPGF
PDTRSSTCSSGEDSVFSHDPLPEEPCLPRHPAQLANGGLKRR
NT seq 2469 nt   +upstreamnt  +downstreamnt
atgtggagctggaagtgcctcctcttctgggctgtgctggtcacagccacactctgccct
gccagagcagccccaacactgcccgaacacgccctgccctggggagcccccgtggaagtg
gagtcctcattggcccaccctggcgatctgctgcagctgcgctgccggctgcgggacgat
gtgcagagcatcaactggctgcgggacggggtgcagctggcggagagcaaccgcacccgc
atcactggggaggaggtggaggtgcgggatgccgtgccctccgactctggcctctacgcc
tgcgtgaccaacagcccctccggcagcgacatcacctacttctccgtcaacgtctcagat
gccctcccatcggctgaggatgacgacgacgatgatgattcctcttccgaagagaaggag
acggacaacaccaaaccaaaccgtacgcctgtggctccctattggacatctccagaaaag
atggagaagaagctgcacgcggtgccggcagccaagacggtgaagttcaagtgtccttca
agcggcacccccagtcctacactgcgttggctgaaaaatggcaaagagttcaaacccgac
caccggatcgggggttataaggtccgttatgccacctggagcatcatcatggactcggtg
gtgccatctgataagggcaactacacctgtattgtggagaacaagtatggcagtatcaac
cacacttatcaactggacgttgtggaacggtcacctcaccggcccatcctgcaggctgga
ctacctgccaacaagacagtggctctgggcagcaacgtggagtttgtatgcaaagtgtac
agtgacccacagccccacatccaatggctgaagcacatcgaggtgaatgggagcaagatt
ggcccagacaacctaccttacgtccagatcctgaagacggccggagttaataccaccgac
aaggagatggaagtgctgcacttaaggaatgtctcctttgaggatgcgggggagtataca
tgcttggcgggtaactctatcgggatctcccatcactctgcatggttgaccgttctggaa
gccctggaggagcgaccggcggtgatgacctcccctctgtacctggagatcatcatctac
tgcacaggggccttcctcatctcctgcatggtggggaccgtcatagtttataagatgaag
agcggcactaagaagagcgacttccacagccagatggctgtacacaagttggccaagagt
attcccctgcgtagacaggtaacagtgtcggctgactccagcacctccatgaactcgggg
gttctgctggtgcggccctcacgcctctcctccagtggaaccccgatgctggctggggtc
tcggagtatgagctgcctgaggatccccgctgggaactgccccgggacaggttggtgcta
ggcaaacctttaggtgagggctgcttcggacaggtggtactggcggaggccattggcctg
gacaaagacaagcccaaccgggtgaccaaggtggcggtcaagatgctgaaatcagatgca
acagaaaaggacctgtcagatctgatctctgaaatggagatgatgaagatgattgggaag
cacaagaacattatcaatctgctgggggcctgcacacaggatggcccgctttatgtcatc
gtggaatatgcatctaagggcaaccttcgtgagtacctccaggcccggcggccccctgga
ttagaatactgttacaaccccagccatgcccctgaggagcaactttcctccaaggatctg
gtctcttgtgcctaccaggtggcccggggcatggaatatcttgcctctaaaaagtgcata
caccgggacctggcagcccggaatgtccttgtgaccgaggacaatgtgatgaagatcgca
gattttggcctggctcgggatatccatcacatcgactactacaaaaagaccaccaatgga
cggctgcctgtgaaatggatggcccctgaggccttgtttgaccggatctacacacaccag
agtgatgtatggtctttcggggtactgctgtgggaaatcttcaccttgggcggctctccc
taccccggcgttcctgtggaggaactcttcaagctgctgaaggagggtcatcgcatggac
aaacctagcaactgcaccaatgacctgtacatgatgatgagggattgctggcatgcggtg
ccttctcagcgacccaccttcaagcagctggtggaggacctagaccgtattgtggccttg
acctccaaccaggagtacctggatctctcagtgcccctggaccagtattcgcccggcttc
ccggacactcgcagttctacctgctcctcgggggaggattctgtcttctcccacgaccca
ctgcccgaggagccctgcctgccccgccacccagcccagcttgctaatgggggactcaag
aggcgctga

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (16)   
   KEGG PATHWAY (16)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (9)   
   RefSeq(pep) (9)   
DNA sequence (10)   
   RefSeq(nuc) (10)   
Protein domain (12)   
   Pfam (12)   
All databases (64)   

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