KEGG   Ornithorhynchus anatinus (platypus): 100074755
Entry
100074755         CDS       T01045                                 
Symbol
ADAM10
Name
(RefSeq) disintegrin and metalloproteinase domain-containing protein 10
  KO
K06704  disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa04148  Efferocytosis
oaa05010  Alzheimer disease
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100074755 (ADAM10)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100074755 (ADAM10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:oaa01002]
    100074755 (ADAM10)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:oaa04090]
    100074755 (ADAM10)
Enzymes [BR:oaa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.81  ADAM10 endopeptidase
     100074755 (ADAM10)
Peptidases and inhibitors [BR:oaa01002]
 Metallo peptidases
  Family M12: astacin/adamalysin family
   100074755 (ADAM10)
CD molecules [BR:oaa04090]
 Proteins
  100074755 (ADAM10)
SSDB
Motif
Pfam: Reprolysin_2 Reprolysin_5 Reprolysin_3 ADAM10_Cys-rich Reprolysin_4 Disintegrin Reprolysin Pep_M12B_propep Peptidase_M66
Other DBs
NCBI-GeneID: 100074755
NCBI-ProteinID: XP_028926261
Ensembl: ENSOANG00000009151
Position
8:2865427..2987822
AA seq 749 aa
MVLLRVSILLFSWAAGLGGQYGNPLNKHIRHYEGLSYEVDVLHQKHQRAKRAVSHEDQFL
RLDFHAHGRHFNLRMKRDTALFSDDFKVETSDNVVDYDTSHIYTGHIYGEEGSFSHGSVI
DGRFEGFIQTRGGTFYVEPAERYIKDRALPFHSVIYHEDDIKYPHKYGPQGGCADHSVFE
RMRKYQMTGVEEATQKHYEEHVTKGPELLRKKRAASAEKNTCQLYIQTDHLFFKYYGTRE
AVIAQISSHVKAIDTIYQSTDFSGIRNISFMVKRIKINTTSDERDPTNPFRFPNIGVEKF
LELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGKKKSLNT
GIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGESKNLGQKENGNYIMYAR
ATSGDKMNNNKFSLCSIRNISQVLEKKRNNCFVESGQPICGNGMVEPGEECDCGYSDQCK
DDCCYDANQAEDKKCKLKPRKACSPSQGPCCTAKCEFKPNSAKCREDSDCAREGVCNGIT
ALCPASDPKPNFTDCNRHTQVCINGQCAGSICEKYGLEECTCASSESKDDKELCHVCCMK
KMDPSTCASTGSSQWNSQFNGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKKA
IFNPELYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSNPKLPPPKPLPGTL
KRRRPPQQTQPPPPRQRPRESYQMGHMRR
NT seq 2250 nt   +upstreamnt  +downstreamnt
atggtgttgctgagagtgtcgatcctgctgttctcctgggctgccggactgggaggccaa
tatggaaaccctttaaataagcacattaggcattatgaaggattatcgtacgaggtggat
gtattacaccaaaaacaccagcgtgccaagcgagcagtatcacacgaagaccagtttttg
cgtctcgattttcatgcgcacggacgacacttcaaccttcggatgaaacgggataccgct
ctcttcagtgatgattttaaagtagaaacgtcagataacgtagttgattatgatacctct
cacatttacactggacatatttatggtgaagagggaagttttagccacggatcggtcatt
gacggacgtttcgaagggttcatccagacccgcggtggcacgttctacgtggagccggcc
gagagatatattaaggatagagctctcccatttcactcggtcatctatcatgaagatgat
atcaaatatccccacaagtacgggccacaaggaggctgtgccgatcattccgtgtttgag
aggatgagaaaataccagatgacgggcgtagaggaagccactcagaaacattacgaagaa
catgtcacgaaaggtccggagctgttgaggaaaaagcgtgcggcttcagctgaaaaaaac
acgtgtcagctttacattcagacagaccatctcttcttcaagtactacggaacccgggaa
gccgtgattgctcagatctccagtcacgtgaaagcgatcgatacaatatatcagtcaacc
gacttctcagggatccgtaacatcagcttcatggtcaaacgaataaagatcaacaccacc
agcgacgagagggaccccaccaatccctttcgtttccccaacatcggcgtggagaagttc
ctggagttgaactcggagcagaaccacgacgattactgcctggcctacgtgtttacggac
cgggactttgacgatggggtcctcggattggcgtgggtcggcgccccctcagggagctct
ggcggaatctgcgagaaaagcaaactgtattcagacgggaaaaagaagtccctgaacacc
ggcatcatcaccgttcagaactacggctcccacgtccctccgaaagtctcccacatcact
tttgctcatgaagttggacacaactttggttcgcctcacgattccggaacggagtgcact
ccgggagaatccaagaatttagggcagaaggaaaatggcaattacatcatgtacgcccga
gcgacgtccggagacaagatgaacaataacaaattttctctctgtagcatccgcaatatc
agccaggtgctcgaaaagaagagaaacaactgttttgtcgaatccggccagccaatctgt
ggaaacggcatggtggaaccaggggaagagtgtgattgtggctacagcgatcagtgtaaa
gatgactgctgctatgacgccaaccaggctgaagataaaaagtgcaaactgaagcccagg
aaagcctgcagccccagccaaggcccctgctgcaccgcaaaatgtgaattcaagcccaat
tccgccaagtgccgcgaagattccgactgcgcgagagagggagtctgtaacggaatcacc
gcgctctgcccggcttcggatcccaaacccaacttcacagactgtaatagacacacccaa
gtgtgcattaatgggcaatgcgccggctccatctgtgagaagtacggcctggaggaatgc
acgtgtgccagttcggaaagcaaggacgacaaggagctctgccacgtctgttgtatgaag
aaaatggacccttccacctgtgcgagcacgggatcgtctcagtggaactcccagttcaac
gggcgaaccatcacgctgcagccgggctccccctgcaacgattttcgtggctactgtgac
gtcttcatgcggtgccgactggtcgacgccgacggccccctcgcccggctgaagaaagcc
atctttaacccagagctgtacgaaaacatcgccgagtggattgtggctcactggtgggca
gtgttgctaatgggaatcgctctgatcatgctaatggctggatttatcaagatctgcagt
gttcacacaccaagcagcaatccaaagttgcctcctcctaaaccactaccaggcacttta
aagaggaggagaccgccccagcagacgcagccgccgccgccacgccagaggccccgggag
agttaccagatggggcacatgagacgctaa

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