KEGG   Ornithorhynchus anatinus (platypus): 100077046
Entry
100077046         CDS       T01045                                 
Symbol
FLNA
Name
(RefSeq) filamin-A isoform X1
  KO
K04437  filamin-A
Organism
oaa  Ornithorhynchus anatinus (platypus)
Pathway
oaa04010  MAPK signaling pathway
oaa04510  Focal adhesion
oaa05132  Salmonella infection
oaa05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:oaa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100077046 (FLNA)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100077046 (FLNA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100077046 (FLNA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100077046 (FLNA)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:oaa04812]
    100077046 (FLNA)
   04147 Exosome [BR:oaa04147]
    100077046 (FLNA)
Cytoskeleton proteins [BR:oaa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Cross-linking proteins
     100077046 (FLNA)
  Intermediate filaments
   Intermediate filament-binding proteins
    100077046 (FLNA)
Exosome [BR:oaa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   100077046 (FLNA)
SSDB
Motif
Pfam: Filamin CH Big_3_5 Y_Y_Y YtkA Invasin_D3 CFSR CH_2
Other DBs
NCBI-GeneID: 100077046
NCBI-ProteinID: XP_028923661
Ensembl: ENSOANG00000011016
Position
6:complement(19107331..19170534)
AA seq 2656 aa
MSSSHSRHNQSGAAVAGGGGGGGGGGGVGGGGDKEAEMPATEKDLAEDAPWKKIQQNTFT
RWCNEHLKCVNKRIANLQTDLSDGLRLIALLEVLSQKKMYRKYNQRPTFRQMQLENVSVA
LEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWDEEEDEETKKQTPKQ
RLLGWIQNKLPQLPITNFSKDWQSGRALGALVDSCAPGLCPDWDSWDASKPVNNAREAMQ
QADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPKLNPKKARAYGPG
IEPSGNMVKKRAEFTVETISAGQGEVLVYVEDPAGHREEAKVIANNDKNRTFSVWYIPKV
TGTHKVTVLFAGQHIAKSPFEVNVDKSHGDASKVTAQGPGLEPSGNIANKTTYFEIFTAG
AGVGEVEVVIQDPTGKKGTVEQQLEDKGNSTYRCTYKPTLEGTYTIYITFAGVPIPRSPY
TVTIGQACNPNACRAVGRGLQPKGVRVKETADFKVYTKGAGSGELKVVVKGPKGEERVKQ
KDLGDGVYAFEYYPTAPGNYIVTITWGGQNISRSPFEVKVGTECGNQKVRAWGPGLEGGV
VGKSADFVVEAIGDDVGTLGFSVEGPSQAKIECDDKGDGSCDVRYWPQEAGEYAVHVLCN
NEDIKLSPFMAEIKTAPKDFYPEKVKARGPGLEKTGVAINKPAEFTVDAKNGGKAPLKVQ
VQDSEGSPVEVSVKDNGNGTYNCSYVPKKPVKHTAMVSWGGVNIPNSPYRVNVGAGSHPN
KVKVYGPGVAKTGLKAHEPTYFTVDCTEAGQGDVSIGIKCAPGVVGPAEADIDFDIIRND
NDTFTVKYTPRGAGSYTIMVLFADQATPTSPIRIKVDPSHDASKVKAEGPGLNRSGVELG
KPTHFNVNAKPAGKAKLDVQFTGPAKGDAVQDVDVIDHHDNTYTVKYTPVQQGNMGVNVT
YGGDHIPKSPFSVGVAQTLDLNKIKVSGLGEKVEVGKDQEFTVKSKGAGGQGKVGAKIIG
PSNKSVPCKVEPGLSADNSVVKFIPREEGPYEVEVTYDGVPVPGSPFPVEAVPPTNPSKV
KAYGPGLKGGSAGSPAPFTIDTKGAGNGGLGLTVEGPCEAKIECLDNGDGTCSVSYLPTE
PGEYSINILFADSHIPGSPFKAQIAPCFDPSKVKCSGPGLEHATVGEAGQFHVDCSSAGS
AELTIEIISDTGMQAEVRIQDNGDGTYTITYIPLYPGVYTITIKYGGQMVPDFPSKLKVE
PAVNTAGVKCYGPGVEGKGVFREATTEFNVDARALTKAGGPHIKTRVSNPSGNLTDTYVQ
DNGDGTYKVEYTPYEEGVHSVDVTYDGSPVPSSPFHVPVTEGCDPARVRVHGPGIQSGTT
NKPNKFTVETRGAGTGGLGLAVEGPSEAKMSCTDNKDGSCSVEYIPYEPGTYSLNVTYGG
HQVPGSPFKVPVHDVIDSSKVKCSGPGLSPGVVRANVPQSFQVDTSKAGVAPLQVKVQGP
KGVVEPVDVVDNADGTQTVNYVPSREGPYSISVLYGDEEVPRSPFKVKVLPTHDASKVKA
SGPGLNTTGVPASLPVEFTIDAKDAGEGLLAVQITDPEGKPKKTTIRDNQDGTYTVSYVP
DMTGRYTILIKYGGDEIPYSPYRIRALPTGDASKCTVTVSIGGHGLGAGIGPTIQIGEET
VITVDAKAAGKGKVTCTVCTPDGSEVDVDVVENEDGTFDIFYTAPQPGKYVICVRFGGEH
IPNSPFQVMALDGDQPAAQQMMPQQLAPPYPYPPGMQQPWATDRPLMGVNGLDVAGLRPF
DLVIPFTIKKGEITGEVRMPSGKVAKPDITDNKDGTVTVRYAPTEAGLHEMDIRYDNMHI
PGSPLQFYVDYVNSGHVTAYGPGLIHGVVNKPAVFTVNTKDAGEGGLSLAIEGPSKADIG
CTDNQDGTCTVSYLPVLPGDYNILVKYNDKHIPGSPFTAKITGDDSIRMSHLKVGSAADI
PLNITETDISQLTATVIPPSGREEPCLLKRLRNGHVGISFVPKEIGEHIVNIKKNGHHIP
NSPITVTISQSEIGDASRVRVSGPGLSEGRTFEPAEFIIDTRDAGYGGLSLSIEGPSKVD
INTEDLEDGTCKVTYCPTEPGNYIINIKFADQHVPGSPFSVKVTGEGRVKESITRKQRAP
SVANVGSHCDLSLKIPEINIRDMTAQVTSPSGKTHEAEIMEGENNTYCIRFVPTEMGVHT
VNVKYKGQHVPGSPFQFTVGPLGEGGAHKVRAGGPGLERAEAGVPAEFSIWTREAGAGGL
SIAVEGPSKAEIAFEDRKDGSCGVSYIVQEPGDYEVSVKFNDDHIPDSPFVVPVASPSDD
ARRLTVSSLQESGLKVNQPASFAVSLNGAKGVIDAKVHSPSGALEECYVTEIDQDKYAVR
FIPRENGIYLIDVKFNGSHIPGSPFKIRVGEPGQGGDPGMVSAYGAGLEGGITGSPAEFI
VNTTGAGAGALSVTIDGPSKVKMDCQECSEGYKVTYTPMAPGSYLISIKYGGPYHIVGSP
FKAKVTGPRLVSSHSLHETSSVFVDSVTKADAVLQQGAPPKFHSDASKVVAKGLGLNKAF
VGQKNSFTVDCSKAGNNMLLVGVHGPKTPCEEILVKHLGNRLYNVTYLLKDKGDYTLVVK
WGEDHIPGSPFHLTVP
NT seq 7971 nt   +upstreamnt  +downstreamnt
atgagcagctcccactccaggcacaaccagagcggtgctgcggtcgcaggaggaggaggt
ggaggtggaggaggaggtggggtcggaggagggggcgacaaggaggccgagatgccagcc
accgagaaggacctggccgaagacgcgccctggaaaaagatccagcagaacaccttcacc
cgctggtgcaacgagcacctgaaatgcgtcaacaaacgcatcgccaacctgcagaccgac
ctgagcgatgggctgcggctgatcgcgctgctggaggtgttgagccagaagaagatgtac
cgcaagtacaaccagcgccccactttccgccagatgcagctggagaacgtgtccgtggcc
ctcgagttcctggaccgggagagcatcaagctcgtgtccatcgacagcaaagccatcgtg
gatgggaacctgaagctgatcctggggctgatatggacgctgatcctgcactactccatc
tccatgcccatgtgggacgaggaggaggacgaggagaccaagaagcagacccccaagcag
cgactcttgggttggattcaaaacaagcttccccagctgcccatcaccaacttcagcaaa
gactggcagagcggcagggccctgggcgccctcgtggacagctgtgcccctggtctgtgc
ccggactgggattcctgggatgccagcaagcctgtgaacaatgctcgggaagccatgcag
caggcggatgattggctgggaatacctcaggtgatcactccagaggagattgtggacccg
aacgtggatgagcactctgtcatgacctacctatcgcagttccccaaggccaagctgaag
ccgggggcccctctccgccccaagctgaaccccaagaaggccagagcctatgggccaggc
attgagcccagtggcaacatggtgaagaaacgggccgagttcactgtggagaccatcagc
gccggccagggcgaggtgctggtgtatgtggaagaccctgccggacaccgggaggaggct
aaagtgattgccaacaatgacaagaatcgcactttctctgtgtggtatatccccaaagtg
actggaacccacaaggtgaccgtgctcttcgccggccagcacattgccaagagccccttc
gaggtgaacgtggacaagtcccacggtgacgccagcaaggtcacggcccagggacccggc
ctggagccgagcggcaatatcgccaataagaccacctactttgagatcttcaccgctggt
gccggtgtgggcgaggtggaagtggtcatccaggacccgacggggaagaagggcactgtg
gagcagcagctggaagacaagggcaacagcacctaccgctgtacctacaagcccaccctg
gagggcacctacaccatctacatcaccttcgctggggtgcccatccctcggagcccctac
accgtcaccattgggcaagcctgtaaccccaatgcctgccgcgcggtgggccgggggctg
caacccaagggtgtccgcgtgaaggagactgctgacttcaaggtgtacaccaagggagca
ggaagtggtgaactgaaggtcgtggtcaagggaccgaagggagaagagcgtgtgaaacag
aaggatctgggagatggagtatatgcgtttgagtactaccccaccgcgcctggaaattat
atcgtgacaatcacgtggggaggtcagaacatctccagaagccccttcgaggtgaaagtg
ggcacagagtgtgggaaccagaaggtgcgagcatggggtcccggcctggaaggaggtgtg
gtcggcaagtccgctgactttgtggtggaagccatcggggatgacgttggcacacttggt
ttctccgtggagggcccatcgcaggccaagatcgagtgtgatgacaagggagatggctca
tgcgacgtgcgatactggccgcaggaggcaggcgagtatgccgtccacgtcctctgcaac
aacgaggacatcaagctcagccccttcatggcggagatcaagaccgcaccaaaggacttc
tacccggagaaggtgaaggcccgaggtcctggtttggagaagacaggtgtggccatcaac
aaacctgctgagttcaccgtcgatgccaagaatggtggaaaggccccactcaaagtccaa
gtgcaggacagcgagggctctcctgtcgaagtctccgtgaaggacaatggcaacggcacc
tacaactgctcttacgtccccaaaaagccagtgaagcacacggccatggtgtcctggggg
ggagtcaacatccccaacagcccctaccgggtcaacgtaggagctggtagccaccccaat
aaagtgaaggtctatggaccaggagtggccaagactggcctcaaggcccacgaacctacc
tactttactgtggactgcacagaggctggccagggcgatgtgagcatcggcatcaagtgt
gccccgggagtcgtggggccggctgaggcagatatcgactttgacatcatccgcaacgac
aacgacaccttcacggtcaagtacaccccccgtggggccggcagctacaccatcatggtg
ctgttcgctgaccaggctacacccaccagccctatccgcatcaaggtggacccctcccac
gatgccagcaaggtcaaggccgagggacctgggctcaacaggagtggcgtggagctgggc
aaacccactcacttcaatgttaatgccaagcctgcgggcaaggccaagctggacgtccag
ttcaccggtcctgccaagggggatgccgtgcaggacgtggatgtcatcgatcaccacgac
aacacgtacaccgtcaagtatacgccggtgcagcagggcaacatgggagtgaatgtgacc
tacggaggagaccacattcccaagagccctttctccgtgggtgtcgcccagaccctggac
ctcaacaagatcaaagtttctggccttggcgagaaagttgaagtcggcaaagaccaggag
ttcacagtcaagtccaaaggcgccgggggccagggcaaggtgggcgccaagatcatcggc
ccctccaacaaatccgtgccctgcaaggtggagccgggcctgagcgcggacaacagtgtc
gtcaagttcattccccgggaggaaggaccctatgaggtggaagtgacctacgacggtgtg
cctgtgccgggcagccccttccccgtggaggccgtacccccaaccaacccatctaaggtg
aaggcctatggcccgggtctcaagggcggctctgccggctcccccgcccccttcaccatc
gacaccaagggggctggcaacggaggcctgggcctgactgtggagggcccctgcgaggcc
aagatcgagtgcctggacaatggcgatggcacctgctccgtgtcctacctgcccacggag
ccgggcgagtacagcatcaacatcctgtttgccgacagccacatccctggctcgcccttc
aaggcccagatcgccccctgtttcgacccctccaaggtcaaatgctctgggcctgggctg
gagcacgccacagtcggggaagccggccagttccacgtggactgctccagcgccggaagt
gccgagctgaccatcgagatcatctcggacaccggcatgcaggccgaggtgcgcatccag
gacaacggggacggcacctataccatcacctacatccccctctatccgggcgtctacacc
atcaccatcaagtacggtggccagatggtgccagacttccccagcaagctgaaggtggag
ccagccgtcaacaccgccggcgtcaagtgctacggtcctggtgtggagggcaaaggtgtc
ttccgggaggctaccaccgaattcaatgtggatgcccgagccctgaccaaggctggaggc
ccccacatcaagacccgggtgtccaatccgtcaggcaatctgaccgacacctatgtgcag
gacaatggggatggcacatacaaagtggagtacacgccatatgaggaaggtgtccactct
gtggatgtgacttatgacggcagcccggtgcccagcagcccattccacgtccctgtgact
gaagggtgtgaccccgccagggtccgggtccacgggcctggcattcagagtggcactacc
aacaaacccaacaagttcactgtggagaccaggggagcaggcactgggggtctcggtttg
gctgtggaaggcccttcagaagccaagatgtcctgcacagacaataaggacggcagttgc
tctgtggaatacattccttatgagcctggcacctacagcctcaatgtcacctatgggggc
caccaagttccgggcagcccattcaaggtgccggtgcatgatgtaatagactcatccaag
gtgaagtgctcagggcctggactcagccctggggtggttagagccaacgtcccacagtcc
ttccaagtggataccagcaaggctggggtggcaccactccaggtcaaagttcaaggcccc
aaaggggtggtggagccggtggacgtggtggacaatgccgatgggactcagacggtcaac
tacgtgccaagccgagaaggtccttacagcatctctgtgctttacggggatgaagaggtg
ccacgcagtcccttcaaggtgaaggtcctgcccactcatgatgccagtaaagtgaaggcc
agcggtcccggactcaacaccaccggcgtgccagccagcctcccggtggagtttaccatt
gatgccaaggatgctggcgaaggccttctggctgtccaaatcacggaccccgaagggaag
cccaaaaagacaaccatccgggacaaccaggacggcacctacacggtgtcctacgtgccg
gacatgactggccgctacaccatcttgatcaagtacggtggagatgagatcccgtactct
ccctaccgcatccgggccctgcccaccggcgatgccagcaagtgcacagtcacagtgtca
attggaggtcacgggctaggcgccggcatcggccccaccatccagatcggcgaggagacg
gtgatcacggtggatgccaaggccgcgggcaagggcaaggtgacttgcacggtctgcacc
ccggatggctcggaggtggacgtggacgtggtggagaacgaggacggcaccttcgacatc
ttctacacggccccccagcccggcaaatacgttatctgtgtgcgctttggtggcgagcac
atccccaacagccccttccaagtcatggcgctggatggtgatcagccggccgctcagcag
atgatgccacagcagctagccccaccctatccatacccgccgggcatgcagcaaccctgg
gcaaccgaccgcccgctgatgggagtgaacggattggatgtggctggcctgcgacctttt
gacctggtcatccccttcaccatcaagaagggagagattacaggtgaagtccgtatgcca
tctgggaaggttgccaagccggacatcacggacaacaaggacgggaccgtgacggtgagg
tacgccccaacggaagccgggctgcatgagatggacatccgctacgacaacatgcacatt
ccaggaagccccttgcagttctacgtggattacgtcaacagcggccacgtgacagcctat
ggacctggactgatccacggggtggtcaacaagccggctgtcttcaccgtcaacacgaag
gatgctggcgagggcggcctgtccctggccatcgagggtccttccaaggctgacatcggc
tgtaccgacaaccaggatggcacctgcacagtctcctacctccccgtcctgcctggcgac
tacaacatcctggtcaaatacaacgataaacacatccccggcagccccttcacagctaaa
atcacaggggacgactcgatacgcatgtcccacttgaaagtgggctctgccgcggacatc
cccctcaacatcaccgagacggacatcagccagctgacagccacagtcatcccgccctca
ggccgtgaagagccctgcctactcaagaggctgcgcaacggccatgttggtatctccttc
gtccccaaggagatcggcgagcacatagtgaacatcaagaagaacggccatcacatcccc
aacagccccatcaccgtgaccatcagccagtcggagatcggggatgccagccgggtgcgg
gtctcgggcccgggcctgagcgagggccgaacctttgagcctgcagagttcatcatcgac
acccgggatgcgggctatggtggcctcagtctctccatcgagggccccagcaaggtggac
atcaacaccgaagacctagaagatggcacctgcaaagtcacctactgtcccacagagcct
ggcaactacatcatcaacatcaagtttgctgaccagcacgtgccaggcagcccattctcc
gtaaaggtgacaggagaaggccgggtcaaggagagcatcacccgaaaacagcgtgccccc
tcagtggccaatgttggcagccattgcgacctcagcctgaagatcccagaaatcaacatc
cgggacatgacggcccaggtgaccagtccttcgggcaagacccacgaagccgagatcatg
gaaggcgaaaacaacacctactgcatccgcttcgtgcccacggagatgggcgtccacacg
gtcaatgtcaagtacaagggccagcatgtccccggaagccccttccagttcaccgtgggg
cccttgggagaaggcggggcccacaaggtgcgggccggaggccccggcctcgagcgagca
gaagccggagtgccagcggagttcagcatttggacccgagaggctggtgctgggggcctg
tccattgccgtggagggtcccagcaaggctgagatcgctttcgaggaccggaaggatggt
tcatgtggtgtgtcctacatcgttcaagagcctggtgactacgaggtctcggtgaagttc
aatgatgaccacatccccgacagccccttcgtggtgcccgtggcctcaccttcggacgac
gctcgccgcctcactgtttctagtcttcaggagtcagggttaaaggtcaaccagccagcc
tcttttgcagtcagcctcaacggggccaagggcgtgattgatgccaaagtgcacagcccg
tcaggggccctggaggaatgctacgtcactgagatagaccaagacaaatacgccgtgcgc
ttcattccccgcgagaatggcatctacctgattgacgtcaagttcaacggctcccacatc
cccggcagccctttcaagatccgcgtcggggagcccgggcaaggcggggacccgggcatg
gtctccgcctatggggctggcttggaagggggcatcacagggagcccggccgagttcatc
gtgaacaccaccggcgcgggcgcgggagctctgtccgtcaccatcgacggcccctccaag
gtgaagatggactgccaggagtgctctgagggctacaaggtcacctacacgcccatggcg
cctggcagctacctgatttccatcaaatacgggggtccctatcacattgtgggcagtccc
ttcaaggccaaggtcacaggtccccgcctggtgagcagtcacagcctccacgagacctct
tctgtttttgtggactcggtgaccaaggcggatgcggttctgcagcagggagccccgccc
aagttccactcggatgccagcaaagtggtggccaagggactggggctcaacaaggccttt
gtgggccagaagaactcattcaccgtcgactgcagcaaagcaggaaacaacatgctcttg
gtcggggtccatgggccgaagaccccgtgtgaggagatcctggtgaaacacctaggcaac
cggctctacaacgtcacctacctgctgaaggacaagggcgactacaccttggtggtcaag
tggggggaagaccacatccccgggagtcccttccacctgactgtcccttaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (35)   
   KEGG ORTHOLOGY (1)   
   RefGene (30)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (8)   
   Pfam (8)   
All databases (59)   

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