KEGG   Ovis aries (sheep): 100462743
Entry
100462743         CDS       T03117                                 
Symbol
DUOX2
Name
(RefSeq) dual oxidase 2 precursor
  KO
K13411  dual oxidase [EC:1.6.3.1 1.11.1.-]
Organism
oas  Ovis aries (sheep)
Pathway
oas04918  Thyroid hormone synthesis
Brite
KEGG Orthology (KO) [BR:oas00001]
 09150 Organismal Systems
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    100462743 (DUOX2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:oas04131]
    100462743 (DUOX2)
Enzymes [BR:oas01000]
 1. Oxidoreductases
  1.6  Acting on NADH or NADPH
   1.6.3  With oxygen as acceptor
    1.6.3.1  NAD(P)H oxidase (H2O2-forming)
     100462743 (DUOX2)
Membrane trafficking [BR:oas04131]
 Others
  NADPH oxidases (Nox) and associated proteins
   NADPH oxidases
    100462743 (DUOX2)
SSDB
Motif
Pfam: An_peroxidase NAD_binding_6 FAD_binding_8 Ferric_reduct EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 NAD_binding_1 PepSY_TM EF-hand_5
Other DBs
NCBI-GeneID: 100462743
NCBI-ProteinID: NP_001177321
EnsemblRapid: ENSOARG00020011873
UniProt: D7REY2
Position
7:63432831..63452164
AA seq 1547 aa
MLRGRPEVLVLLGILLSLLLDPTGGQDSFSLTWEVQRYDGWFNNLRHHERGAAGSRLQRL
APANYADGVYQALEEPLLPNPRRLSNAATRGSSGRPSGRNRTVLGVFFGYHVLSDLVSVE
KSACPAEFLNIHIPPGDPVFDRDQSGDVVLPFQRSRWDPETGQSPSNPRDLTNEVTGWLD
GSAIYGSSHSWSDELRSFSGGELASGPDPAFPRAAQAPLLMWTPPDPTTGRRGPRGLYAF
GAERGNREPFLQALGLLWFRYHNLWAQKLASRYPLWGDEELFQHARKRVIATYQNIAMYE
WLPSFLQQTPPNYTEYRPFLDPSISPEFLAASEQFFSTMVPPGVYMRNASCHFQMVLNEG
FGSSPALRVCNSYWIRENPNLNSSQAVNQLLLGMASQISELEDSTVVEDLRDYWPGPGKF
SRTDYVASSIQRGRDMGLPSYSQALQALGLMIPRNWSDLNPNVDPQVLEATAALYNQDLS
RLELLPGGLLESHGDPGPLFSTIVLDQFVRLRDGDRYWFENSRNGLFSPEEIAEIRSTTL
RDVLVAVTNVDPDTLQPNVFIWQNGAPCPQPQQLTTEDLPPCVPLTEIHYFEGSGPGFGI
TIVALCCLPLVSLLVSGVVAYFRGRERKKLQRKGKESVKKEAASDGVSAMEWPGPRERGY
PVTIQLLPDRRLQVVDRRLSVLRTIQLQPPQQVNLILSSNRGCRALLLKIPKEYDLVLLF
NSQEERGAFVQHLRGFCENWSLGLEVAHMSEYELFRKAVTKEQRERILEVFFRHLHLFAQ
VLDINQVDAGTLLLDSSQKVREALTCELSRAEFAESLGLKPQDMFVESMFSLADKDGNDY
LSFREFLDVLVVFMKGSPEDKSRLMFTMYDLDGNGFLSKDEFFTMMRSFIEISNNCLTKT
QLAEVVESMFRESGFQDKQELTWEDFHFMLRDHDSELRRTQLCVRGGGGGVGDIFKPNIS
SRVSFIARTSEERSCPQRVGLSASKAPELGGPGLKKRFGKKAGVPPPRLYTEALQEKMQR
GFLAQKLQQYKRFVENYRRHIVCVAVFSAICAGLFVERAYYYAFASPPSGIAQTTFVGII
LSRGTAASVSFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRWIAMAAVVLAILH
SAGHVVNVYIFSVSPLSLLACIFPSVFVNDGSKLPQKFYWWFFQTVPGMTGVLLLLVLAI
MYVFASHHFRRRSFRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIYFLVPALIYMGDK
LVSLSRKKVEIGAVKAQLLPSGVTHLEFQRPQGFEYKSGQWVRIACLALGTNEYHPFTLT
SAPHEETLSLHIRAVGPWTTRLRETYSLPTGDSSAKYPKLYLDGPFGEGHQEWHKFEVSV
LVGGGIGVTPFASILKDLVFKSSLGSQMLCKKIYFIWVTRTQRQFEWLADIIREVEENDC
QDLVSVHIYITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFERFFCS
LQEVHPKVRKIGVFSCGPPGMTKNVEKACQLINQQDQAHFVHHYENF
NT seq 4644 nt   +upstreamnt  +downstreamnt
atgctccgcggaaggccagaggtacttgtgctcctgggaattctgctgtctctgctcctg
gatccaacgggtggccaggactcattctcactgacctgggaagtgcagcgctatgacggc
tggttcaacaacctgaggcaccacgagcgtggcgctgcgggctcccgactgcagcgcctt
gcaccggccaactatgcggacggcgtgtatcaggctctcgaggagccgctgctgcccaac
ccgcgcagactcagcaacgcagccacgcggggcagctccgggaggccgtccggccgcaat
cgcacggtcctgggggttttcttcggctaccatgtgctgtcggacctggtcagcgtggaa
aagtctgcctgcccagccgagttcctcaacatccacatcccgcccggagaccccgtgttc
gaccgcgaccagagcggggacgtggtcctgcccttccagaggagtcgctgggaccccgag
accggacagagccccagcaacccccgggacctgaccaacgaggtgaccggctggctggac
ggcagcgccatctatggctcctcgcactcctggagcgacgagctgcggagcttctccggg
ggggaactggcgtcggggcccgaccccgctttccctcgggccgcgcaggccccgctgctc
atgtggacgccgccagatcccaccactggccgccgcgggccgcgggggctatacgccttc
ggggccgagcgagggaaccgcgagcccttcctgcaggcgctgggtctgctctggttccgc
tatcacaacctgtgggcgcagaagctggccagccggtacccgctctggggggacgaggag
ctgttccagcacgcgcgcaagagggtcatcgccacctaccagaatatcgccatgtatgag
tggctgcccagcttcctgcagcaaacacctccaaattacacagagtatcgccctttcctg
gaccccagcatctccccggagttcctggctgcctctgagcagttcttctccaccatggtg
ccccctggcgtctacatgagaaatgccagctgtcatttccagatggtcctgaacgagggt
tttggcagctccccagctctcagagtctgcaacagctactggattcgggagaatcccaat
ctgaacagctctcaggcagtgaatcagctactgctgggaatggcctcccagatctcagag
ctggaggacagtactgtggtggaagatctgagggattactggcctggccctggcaagttc
tctcgcactgactacgtggccagcagcatccaacgtggccgagacatggggctgcccagc
tatagccaagctctgcaggccttggggctgatgatcccgaggaactggagtgacctcaac
cccaatgtggaccctcaggtgctggaggccacggcggccctgtacaaccaggacctgtcc
cggctggagctactccctggggggctcctggagagccacggggaccctggacccctcttc
agcaccattgtccttgatcagtttgtgcgactgcgggatggcgaccgctactggtttgag
aacagcaggaatgggctcttctctccagaggaaattgcagaaattagaagcaccactctt
cgggatgtgctggtggctgtcaccaatgtggaccctgacaccctgcagcccaatgtcttt
atttggcagaatggtgcaccctgccctcagccccaacagctcacaaccgaagacctgccc
ccctgtgtgcccctgaccgagattcattacttcgagggcagtggtcctggttttggcatc
accatcgtggctttgtgctgtcttccactagtgagcctacttgtctctggggtggtggcc
tatttccggggccgagagcgcaagaagctccaaaggaaaggcaaagagagtgtgaagaag
gaagcagccagtgatggagtgtcagcaatggagtggccgggcccccgggagaggggctat
ccagtcaccatccagctgctcccagaccggcggctgcaggttgtggaccggcggctctct
gtgctccgcaccatccagctgcagcccccacaacaggtcaacctcatcctgtccagcaac
cgcggatgccgcgccctgctgctcaagatccccaaggagtatgatctggtgctgctgttt
aactcccaggaagagcggggcgccttcgtgcagcatctgcggggcttctgtgagaactgg
tctctgggcctggaggtggctcacatgagcgagtatgagctgttcaggaaagctgtgacc
aaagagcagcgggaacgcatcctggaggttttcttcagacacctacacctttttgcccag
gtgctggatatcaaccaggtggatgcagggaccctgctcctggactcatcgcaaaaggtg
cgggaggccctgacgtgtgagctgagccgggccgagtttgccgagtccctgggcctcaag
ccccaggacatgtttgtggagtccatgttttctctggctgacaaggatggcaatgactac
ctgtccttccgggagttcctggacgtcctggtggtcttcatgaaaggctccccggaggac
aagtcccgcctgatgttcaccatgtatgaccttgatgggaatggcttcctctccaaggac
gagttcttcaccatgatgcggtccttcattgagatctccaacaactgcctgaccaagacc
cagctggccgaggtggtggagtccatgttccgagagtcaggcttccaggacaagcaggag
ctgacgtgggaagacttccacttcatgctgcgggaccacgacagtgagctccgtcgaacg
cagctctgtgtcagaggtggaggaggaggtgttggagacatttttaaaccaaacatcagc
tctcgagtgtcattcatcgctcggacttctgaggaacgttcttgccctcagagagtgggg
ctctctgcctcgaaagccccggagttgggaggccctgggctgaagaagaggtttggcaaa
aaggcaggggtgccccctccccggctgtacacggaggcgctgcaggagaagatgcagcgg
ggcttcctggctcagaagctgcagcagtacaagcgcttcgtggagaactaccggcggcac
atcgtgtgcgtggctgtcttctcggccatctgtgccggactgtttgtggagcgtgcttac
tactacgcctttgcctcgccaccctcgggcattgcacagaccacttttgtgggcatcatc
ctgtcgcgtggcacagcggccagcgtctccttcatgttctcctacatcctgctcaccatg
tgccgcaacctcatcaccttcctgagagagaccttcctcaaccgctatgtgccctttgac
gccgccgtggacttccatcgctggatcgccatggccgctgtggtcctggccattttacac
agtgctggccacgtggtgaatgtctacatcttctcagtcagccccctcagtctgctggcc
tgcatctttcccagcgtctttgtgaatgacgggtccaagcttccccagaagttctactgg
tggttcttccagacagtcccaggtatgacaggggtgctcctgctcctggttcttgccatc
atgtacgtctttgcttcccaccacttccgacgccgcagcttccggggcttctggttgacc
caccacctctacatcctgctctatgtgctgctcatcatccacggcagctttgccctgatc
cagctgccccgtttccacatctacttcctggtcccagcgcttatctacatgggggacaag
ctggtgagcttgagccggaagaaggtggagattggcgcggtgaaggcacagctgctgcct
tcaggagtgacccacctggagttccagcggccccaaggctttgagtacaagtcaggacag
tgggtgcggatcgcctgcctggctctggggaccaatgagtaccaccccttcacgctgaca
tcagcgccccatgaagagacgcttagcctgcacatccgggcggtggggccgtggaccacc
cgcctcagggagacctactcacttccaacgggtgacagctctgccaaatatccaaagctg
tacctcgatgggccatttggagagggccatcaggagtggcataagtttgaggtgtcagtg
ctagtgggagggggcattggggtcaccccctttgcctctatcctcaaagacctggtcttc
aagtcatccttggggagccaaatgctctgtaaaaagatctacttcatctgggtgacgcgg
acccagcggcagtttgagtggctggctgacatcatccgggaggtggaggagaatgactgc
caggacctcgtgtccgtgcacatctacatcacccagctggctgagaagttcgacctcagg
accaccatgctgtacatctgtgagcggcacttccagaaggtgctgaaccggagtctgttc
acgggcttgcgctccatcacccactttggccgccctcccttcgagcgctttttctgttct
ctgcaggaggtccacccgaaggtgcggaagatcggggtgttcagctgtggccctccagga
atgaccaagaatgtagagaaggcctgtcagctcatcaaccagcaggaccaagcccacttc
gtgcaccactatgagaacttctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (12)   
   RefSeq(nuc) (4)   
   GenBank (4)   
   EMBL (4)   
Protein domain (11)   
   Pfam (11)   
All databases (39)   

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