KEGG   Oryctolagus cuniculus (rabbit): 100340670
Entry
100340670         CDS       T03373                                 
Name
(RefSeq) 5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X2
  KO
K07198  5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu04068  FoxO signaling pathway
ocu04140  Autophagy - animal
ocu04150  mTOR signaling pathway
ocu04151  PI3K-Akt signaling pathway
ocu04152  AMPK signaling pathway
ocu04211  Longevity regulating pathway
ocu04213  Longevity regulating pathway - multiple species
ocu04371  Apelin signaling pathway
ocu04530  Tight junction
ocu04710  Circadian rhythm
ocu04714  Thermogenesis
ocu04910  Insulin signaling pathway
ocu04920  Adipocytokine signaling pathway
ocu04921  Oxytocin signaling pathway
ocu04922  Glucagon signaling pathway
ocu04931  Insulin resistance
ocu04932  Non-alcoholic fatty liver disease
ocu04936  Alcoholic liver disease
ocu05410  Hypertrophic cardiomyopathy
ocu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    100340670
   04068 FoxO signaling pathway
    100340670
   04151 PI3K-Akt signaling pathway
    100340670
   04152 AMPK signaling pathway
    100340670
   04150 mTOR signaling pathway
    100340670
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100340670
  09144 Cellular community - eukaryotes
   04530 Tight junction
    100340670
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    100340670
   04922 Glucagon signaling pathway
    100340670
   04920 Adipocytokine signaling pathway
    100340670
   04921 Oxytocin signaling pathway
    100340670
  09149 Aging
   04211 Longevity regulating pathway
    100340670
   04213 Longevity regulating pathway - multiple species
    100340670
  09159 Environmental adaptation
   04710 Circadian rhythm
    100340670
   04714 Thermogenesis
    100340670
 09160 Human Diseases
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    100340670
   05410 Hypertrophic cardiomyopathy
    100340670
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100340670
   04932 Non-alcoholic fatty liver disease
    100340670
   04931 Insulin resistance
    100340670
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ocu01001]
    100340670
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ocu04131]
    100340670
   03029 Mitochondrial biogenesis [BR:ocu03029]
    100340670
Enzymes [BR:ocu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.31  [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase
     100340670
Protein kinases [BR:ocu01001]
 Serine/threonine kinases: CAMK group
  CAMKL family
   100340670
Membrane trafficking [BR:ocu04131]
 Autophagy
  Other autophagy associated proteins
   Others
    100340670
Mitochondrial biogenesis [BR:ocu03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    100340670
  Mitophagy factors
   Other mitophagy factors
    100340670
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr AMPK_alpha_AID AdenylateSensor ABC1 Kinase-like Kdo APH Haspin_kinase
Other DBs
NCBI-GeneID: 100340670
NCBI-ProteinID: XP_008263418
Ensembl: ENSOCUG00000004942
UniProt: G1SMV0
Position
13:complement(110369756..110465436)
AA seq 537 aa
MEERMKKKLPGTFLLTFGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH
IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMV
VHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEV
DIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLK
RATIKDIREHEWFKQDLPTYLFPEDPSYDANVIDDEAVREVCEKFECTESEVMNSLYSGD
PQDQLAVAYHLIIDNRRIMNQASEFYLASSPPAGSFMDDSAMHIPPGLKPHPERMPPLIA
DSPKAKCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVYRAMKQLDFEWKVVNA
YHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQRSGSSTPQRSCSAAGL
HRPRSSFDSTTAESHSLSGSLTGSLTGSTLSSVSPRLGSHTMDFFEMCASLITTLAR
NT seq 1614 nt   +upstreamnt  +downstreamnt
atggaggaaaggatgaagaagaagctgccaggaacatttctgcttacatttggagaacat
caattgacaggccataaagtggcagttaaaatcttaaatagacagaagattcgcagttta
gatgttgttggaaaaataaaacgagaaattcaaaatctaaaactgtttcgccatcctcat
attatcaaactctatcaggtgatcagcactccgacagacttttttatggtaatggagtat
gtttctggaggtgaattatttgattacatctgtaaacatggacgggttgaggagatggaa
gccaggcgcctctttcagcagattctgtctgccgtagattactgtcataggcatatggtt
gttcatcgagacctaaaaccagaaaatgtgcttttggatgcacacatgaatgccaagata
gcagattttggcttatcaaacatgatgtcagacggtgaatttctgcggaccagttgtggg
tccccgaattatgcagcgcctgaagtcatctcaggcagattgtatgcaggtcctgaagtt
gatatctggagctgcggtgttatcttgtatgcgcttctctgtggcactctcccatttgat
gatgaacacgttcccacgttgtttaagaagatccgaggaggtgttttttatatcccggaa
tatcttaatcgctctgtcgccaccctcctgatgcatatgctgcaggttgaccccctgaaa
cgagcaaccatcaaagacataagagaacatgagtggtttaaacaagatttgcccacttac
ttatttcctgaagacccctcctatgatgctaatgtcattgatgatgaggctgtgagagag
gtgtgtgaaaaatttgagtgtacagaatcagaagtaatgaacagtttatatagtggtgac
cctcaagaccagcttgcggtggcttatcatcttatcattgacaatcggagaataatgaac
caagccagtgagttctacctcgcttccagtcctccagcaggttcttttatggatgatagt
gccatgcatattcccccaggacttaaacctcatccagaaaggatgccgcctctcatagca
gacagccccaaagcaaaatgtccgttggatgcactaaatacaactaagcccaaatcttta
gctgtgaaaaaagccaaatggcatcttggaatccgaagtcagagcaaaccatatgacatc
atggctgaagtgtaccgagctatgaagcagctggactttgaatggaaggtagtgaatgca
taccatcttcgagtaagaagaaaaaatccagtgactggcaattatgtgaaaatgagcttg
caactttacctggttgataatagaagctatcttttggactttaaaagcattgatgatgag
gtagtggaacagaggtctggttcctcaacacctcagcgctcctgctctgcggctggctta
cacaggccaagatcaagttttgattctaccactgcagagagtcattcgctttctggctct
ctcactggctctttgacaggaagcacattgtcttcagtttcacctcgcctgggcagtcac
accatggatttttttgaaatgtgtgccagtctgatcactactttagcacgttga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (20)   
   KEGG PATHWAY (20)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (10)   
   RefSeq(nuc) (4)   
   GenBank (3)   
   EMBL (3)   
Protein domain (9)   
   Pfam (9)   
All databases (61)   

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