KEGG   Oryctolagus cuniculus (rabbit): 100342636
Entry
100342636         CDS       T03373                                 
Name
(RefSeq) steroid 21-hydroxylase isoform X1
  KO
K00513  steroid 21-monooxygenase [EC:1.14.14.16]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu00140  Steroid hormone biosynthesis
ocu01100  Metabolic pathways
ocu04925  Aldosterone synthesis and secretion
ocu04927  Cortisol synthesis and secretion
ocu04934  Cushing syndrome
Module
ocu_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    100342636
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    100342636
   04927 Cortisol synthesis and secretion
    100342636
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100342636
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:ocu00199]
    100342636
Enzymes [BR:ocu01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.16  steroid 21-monooxygenase
     100342636
Cytochrome P450 [BR:ocu00199]
 Cytochrome P450, animal type
  CYP21 family
   100342636
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 100342636
NCBI-ProteinID: XP_008260834
Ensembl: ENSOCUG00000007053
UniProt: G1SS94
Position
12:complement(134908815..134914077)
AA seq 493 aa
MLLLGLLLLLALLAAARLLWGQWKLRSLHLPPLVPGFLHLLQPNLPIYLLGLAQKFGPIY
RLRFGLQDVVVLNSKRTIEEAMIKKWVDFAGRPPAPSYKLICEHYPDLSLGDYSLLWKAH
KKLARSALLLGIHDSMEPLVEQLAQEFCERLRAQAGAPVAIQEEFSFLTCSIICSLTFGD
KEDTLVWTVYNNVQDLLKAWGHWSVQMLDMVPFLRFFPNPGVWRLKQVLEHRDRIVERQL
RRHKESLEAGRCRDMMDYMLHGVGRQREEQGPGQLVEGHVHMAVVDLFIGGTETTAITLS
WAVAFLLHHPEIQRRLQEELDLELGPDAAGSRVSYKERARLPLLNATIAEVLRLRPVVPL
ALPHRTTRPSSISGYDIPEGTVIIPNLQGAQLDETVWEQPHEFSPDRFLEPGKSPRLLAF
GCGARLCLGEPLARLELFVVLARLLQAFTLLPPAGTLPSLQPLSCSGVNLLMQPFQVQLQ
PRGPGAASLGQGQ
NT seq 1482 nt   +upstreamnt  +downstreamnt
atgctgctccttgggttgctgctgctgctggccctgctggctgctgcccgcctgctgtgg
ggccagtggaagctcaggagcctccacctcccacctcttgtcccaggtttcctgcacctg
ctgcaacccaacctccccatctatctacttggcctagctcagaaattcgggccaatctat
aggctccgcttcgggctgcaagatgtggtggtgttgaacagtaagaggaccattgaggaa
gccatgatcaaaaagtgggtggactttgccggcagaccccctgcgccgagctacaagctg
atatgtgagcactacccggacctgtcgctaggggactactccctgctctggaaagcccac
aagaaactggcgcgctcggccctgctgctgggcatccacgactccatggagccgctggtg
gagcagctagcccaagagttctgcgagcgcctgagagcccaggccggcgcccccgtggcc
atccaggaagaattctctttcctcacctgcagcatcatctgttccctcaccttcggagac
aaggaggacaccttggtgtggaccgtttacaacaatgtccaggacttgctgaaggcctgg
ggccactggtccgtccaaatgttggacatggttccctttctcaggttcttccccaaccca
ggcgtgtggaggctgaagcaggtcttagagcacagggaccgcatcgtggagcggcagctg
agacggcacaaggagagcctggaggccggccggtgcagggacatgatggactacatgctc
cacggggtgggccggcagagagaggagcagggccccggacagctcgtggaaggtcacgtg
cacatggccgtggtggaccttttcattggcggcaccgagaccacggccatcaccctctcc
tgggctgtggcgttcttgcttcaccaccctgagattcaacggcggctgcaggaggagctg
gacctcgagctgggccccgatgctgcgggctcccgggtctcctacaaggaacgggcgcgg
ctgcccttgctcaatgccaccatcgcggaggtgctgcgcctgaggcccgtggtgcccttg
gccttgccgcaccgcactacacggcccagcagcatctcgggctacgacatccctgagggc
acggtcatcatccccaacctccagggcgcccagctcgacgagactgtctgggagcagccc
cacgagttctccccggaccgcttcctggagccaggcaagagccccaggctgctggctttc
ggctgcggggcgcgcttatgcctgggagaaccgctggcgcgcctggagctcttcgtggtg
ctggcgcggctgctccaggccttcacgctgctgccgcccgcgggcaccctgccctctctg
cagccgctgtcctgcagcggcgtcaacctcctgatgcagccttttcaggtgcagctgcag
ccccgtggcccgggtgccgcgagcctgggccagggtcagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (5)   
   KEGG MODULE (2)   
Chemical substance (16)   
   KEGG COMPOUND (16)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (8)   
   RefSeq(nuc) (2)   
   GenBank (3)   
   EMBL (3)   
Protein domain (1)   
   Pfam (1)   
All databases (63)   

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