KEGG   Orcinus orca (killer whale): 101277640
Entry
101277640         CDS       T05247                                 
Symbol
HDAC2
Name
(RefSeq) histone deacetylase 2
  KO
K06067  histone deacetylase 1/2 [EC:3.5.1.98]
Organism
oor  Orcinus orca (killer whale)
Pathway
oor03082  ATP-dependent chromatin remodeling
oor03083  Polycomb repressive complex
oor04110  Cell cycle
oor04213  Longevity regulating pathway - multiple species
oor04330  Notch signaling pathway
oor04350  TGF-beta signaling pathway
oor04613  Neutrophil extracellular trap formation
oor04919  Thyroid hormone signaling pathway
oor05016  Huntington disease
oor05031  Amphetamine addiction
oor05034  Alcoholism
oor05165  Human papillomavirus infection
oor05169  Epstein-Barr virus infection
oor05200  Pathways in cancer
oor05202  Transcriptional misregulation in cancer
oor05203  Viral carcinogenesis
oor05206  MicroRNAs in cancer
oor05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:oor00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03082 ATP-dependent chromatin remodeling
    101277640 (HDAC2)
   03083 Polycomb repressive complex
    101277640 (HDAC2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    101277640 (HDAC2)
   04350 TGF-beta signaling pathway
    101277640 (HDAC2)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    101277640 (HDAC2)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    101277640 (HDAC2)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    101277640 (HDAC2)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    101277640 (HDAC2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101277640 (HDAC2)
   05202 Transcriptional misregulation in cancer
    101277640 (HDAC2)
   05206 MicroRNAs in cancer
    101277640 (HDAC2)
   05203 Viral carcinogenesis
    101277640 (HDAC2)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    101277640 (HDAC2)
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    101277640 (HDAC2)
   05165 Human papillomavirus infection
    101277640 (HDAC2)
  09164 Neurodegenerative disease
   05016 Huntington disease
    101277640 (HDAC2)
  09165 Substance dependence
   05031 Amphetamine addiction
    101277640 (HDAC2)
   05034 Alcoholism
    101277640 (HDAC2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:oor03036]
    101277640 (HDAC2)
Enzymes [BR:oor01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     101277640 (HDAC2)
Chromosome and associated proteins [BR:oor03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class I HDACs
     101277640 (HDAC2)
   HDAC complexes
    Sin3A-HDAC complex
     101277640 (HDAC2)
    BRAF-HDAC complex
     101277640 (HDAC2)
    REST complex
     101277640 (HDAC2)
    SHIP complex
     101277640 (HDAC2)
    MiDAC complex
     101277640 (HDAC2)
   Polycomb repressive complex (PRC) and associated proteins
    Noncanonical PRC1 (PRC1.6)
     101277640 (HDAC2)
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    101277640 (HDAC2)
  Chromatin remodeling factors
   NuRD complex
    101277640 (HDAC2)
SSDB
Motif
Pfam: Hist_deacetyl
Other DBs
NCBI-GeneID: 101277640
NCBI-ProteinID: XP_004264753
Position
12:45244140..45275586
AA seq 488 aa
MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKA
TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA
GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH
GDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQ
IFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLG
GGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYM
EKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEE
FSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGA
KSEQLSNP
NT seq 1467 nt   +upstreamnt  +downstreamnt
atggcgtacagtcagggaggcggcaagaagaaagtctgctactactacgatggtgatatt
ggaaattattattacggacagggtcatcccatgaaacctcataggatccgcatgacccat
aacttgctgctaaattatggcttgtatagaaaaatggaaatatataggccccataaagcc
actgctgaagaaatgacaaaataccacagcgatgagtacatcaaatttctacgttcaata
agaccagataacatgtccgagtatagtaagcagatgcagagatttaatgtcggagaggac
tgtccagtgtttgatgggctctttgagttttgtcagctttcaactggtggttcagttgct
ggggctgtgaagttaaaccgacaacaaactgatatggctgttaactgggctggaggatta
catcatgctaagaaatcagaagcatcaggattctgttatgttaatgatattgtgcttgcc
atccttgaattactaaagtatcatcagagagtcttatatattgatattgatatccatcat
ggtgatggtgttgaagaagctttttatacaacagatcgtgtaatgactgtatcattccat
aaatatggcgaatactttcctggaacaggagacttgagggatattggtgcaggaaaaggc
aaatactatgctgtcaattttccaatgagagatggtatagatgatgaatcatatgggcag
atatttaagcctattatttcaaaagtgatggagatgtatcaacctagtgctgtggtgcta
cagtgtggtgcagactcactatccggtgatagacttggttgcttcaatttgacagtcaaa
ggtcatgctaaatgtgtagaagtcgtaaaaactttcaatttaccattactgatgcttggg
ggaggtggatacacaatccgcaatgttgctcgatgttggacatacgagactgctgttgcc
cttgattgtgagattcccaatgaattgccatataatgattactttgagtattttggacca
gacttcaaactgcatattagtccttcaaacatgacaaaccagaacactccagaatatatg
gaaaagataaaacagcgtttatttgaaaatttacgcatgttgccacatgcacctggagtc
caaatgcaagctattccagaagatgcagttcatgaagacagtggagatgaagatggagaa
gatccagacaagagaatttctattcgagcatcagacaaacggatagcttgtgatgaagaa
ttctcagattctgaggacgaaggagagggaggtcgtagaaatgtggctgatcataagaaa
ggagcaaagaaagctagaattgaagaagacaagaaggaaacggaggacaaaaaaacagat
gttaaagaagaagataagtccaaggacaatagtggtgaaaaaacagataccaaaggagcc
aaatcagaacagctcagcaacccttga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (18)   
   KEGG PATHWAY (18)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (28)   
   KEGG ORTHOLOGY (1)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (1)   
   Pfam (1)   
All databases (54)   

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