KEGG   Orcinus orca (killer whale): 101288139
Entry
101288139         CDS       T05247                                 
Symbol
EPHX1
Name
(RefSeq) epoxide hydrolase 1 isoform X4
  KO
K01253  microsomal epoxide hydrolase [EC:3.3.2.9]
Organism
oor  Orcinus orca (killer whale)
Pathway
oor00980  Metabolism of xenobiotics by cytochrome P450
oor04976  Bile secretion
oor05204  Chemical carcinogenesis - DNA adducts
oor05207  Chemical carcinogenesis - receptor activation
oor05208  Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:oor00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101288139 (EPHX1)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    101288139 (EPHX1)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    101288139 (EPHX1)
   05207 Chemical carcinogenesis - receptor activation
    101288139 (EPHX1)
   05208 Chemical carcinogenesis - reactive oxygen species
    101288139 (EPHX1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:oor01002]
    101288139 (EPHX1)
Enzymes [BR:oor01000]
 3. Hydrolases
  3.3  Acting on ether bonds
   3.3.2  Ether hydrolases
    3.3.2.9  microsomal epoxide hydrolase
     101288139 (EPHX1)
Peptidases and inhibitors [BR:oor01002]
 Serine peptidases
  Family S33
   101288139 (EPHX1)
SSDB
Motif
Pfam: EHN Abhydrolase_1 Abhydrolase_6
Other DBs
NCBI-GeneID: 101288139
NCBI-ProteinID: XP_004271038
Position
1:complement(10231127..10279765)
AA seq 451 aa
MWLEILLASVLGFVIYWFVSKDKEETLPLEDGWWGPGVRPTAGEDESIRPFKVETSDEEI
NDLHQRIDKVRLSPPLEDSRFHYGFNSNYLKKVISYWRNEFDWRKQVETLNRYPHFKTKI
EGLDIHFIHVKPPQLPSGQTPKPLLMVHGWPGSFYEFYKIIPLLTDPKNHGLSDEHVFEV
ICPSIPGYGFSEASSKKGFDSVATARIFYKLMLRLGFQQFYIQGGDWGALICTNMAQLVP
SHVKGLHLNMAFILRNFYTLTLLLGWRFGRLFGYTKRDMELMYSLKKIFFNLLRESGYLH
IQSTKPDTVGCALNDSPVGLAAYILEKFSTWTNPEFRDLEDGGLERKFSLDDLLTGVMLY
WTTGTITSSQRFYKENMRLDNRHEGIKVHVPMGFAAFPCEVIHVPEKWVKSKYPKLISYS
YMPRGGHFAAFEEPELLAQDIHKFVGLLERQ
NT seq 1356 nt   +upstreamnt  +downstreamnt
atgtggctggaaatactcctcgcctcagtgctgggctttgtcatctactggttcgtctcc
aaggacaaggaggaaactttgccacttgaagatggatggtgggggcccggggtgaggccc
acagccggggaggacgagagcatccgcccattcaaggtggaaacgtcagatgaggagatc
aatgatttacaccagaggattgacaaggtccgtttaagcccacctttggaggacagccgc
ttccactacggtttcaactccaactatctgaagaaagtcatctcctactggcggaatgaa
tttgactggaggaagcaggtggagactcttaacagatatcctcacttcaagactaagatt
gaaggcctggacatccacttcatccacgtgaagcccccccagctgccctccggccagacc
ccaaagcccttgctgatggtgcatggctggcctggctccttctacgagttttataagatc
attccgttgctgactgaccccaagaaccatggcctgagcgatgagcatgtttttgaagtc
atctgtccatccattcctggctacggcttctcagaggcatcttccaagaagggcttcgac
tcagtggccactgccaggatcttttataagctgatgctgcggctgggcttccagcaattc
tatattcaaggcggagactggggagccctgatctgcaccaacatggcccagctggtgccc
agccacgtgaaaggcctgcacttgaacatggcattcattttaagaaatttctacaccctg
acccttctcctgggatggcgttttgggaggctttttggctacaccaagagggatatggag
ctgatgtactccttaaagaagatcttcttcaacttattgagggagagcggctacctgcac
atccagagtaccaagccggacaccgtaggctgtgctctgaatgactctcccgtgggactg
gctgcctatattctagagaagttttctacctggaccaatccagagttccgagacctggag
gatggaggcctggagaggaagttctccctggacgatctgctgacgggcgtgatgctctac
tggacgacaggcaccatcacctcctcccagcgcttctacaaagagaacatgaggctggac
aataggcacgaggggataaaggtccacgtgcccatgggctttgctgccttcccttgtgag
gtaatacacgtcccagaaaagtgggtgaagtccaaatacccgaaactcatctcttattcc
tacatgccccgtgggggccactttgctgcctttgaggagccagagctgctcgcccaggac
atccacaagttcgtggggctgctggagcggcagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical substance (18)   
   KEGG COMPOUND (18)   
Chemical reaction (10)   
   KEGG ENZYME (1)   
   KEGG REACTION (9)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (6)   
   RefSeq(pep) (6)   
DNA sequence (6)   
   RefSeq(nuc) (6)   
Protein domain (3)   
   Pfam (3)   
All databases (69)   

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