KEGG   PATHWAY: afo00630
Entry
afo00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Acidimicrobium ferrooxidans
Class
Metabolism; Carbohydrate metabolism
Pathway map
afo00630  Glyoxylate and dicarboxylate metabolism
afo00630

Module
afo_M00621  Glycine cleavage system [PATH:afo00630]
Other DBs
GO: 0046487 0043648
Organism
Acidimicrobium ferrooxidans [GN:afo]
Gene
Afer_1286  acetate/CoA ligase [KO:K01895] [EC:6.2.1.1]
Afer_1641  AMP-dependent synthetase and ligase [KO:K01895] [EC:6.2.1.1]
Afer_1880  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
Afer_1835  citrate synthase I [KO:K01647] [EC:2.3.3.1]
Afer_2022  citrate synthase [KO:K01647] [EC:2.3.3.1]
Afer_1408  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
Afer_0106  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Afer_0261  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Afer_0104  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
Afer_0223  methylmalonyl-CoA mutase, large subunit [KO:K14447] [EC:5.4.99.63]
Afer_1770  acyl-CoA dehydrogenase domain protein [KO:K14448] [EC:1.3.8.12]
Afer_0231  carboxyl transferase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
Afer_0582  carboxyl transferase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
Afer_0730  Carbamoyl-phosphate synthase L chain ATP-binding [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
Afer_0318  cobalamin B12-binding domain protein [KO:K01849] [EC:5.4.99.2]
Afer_0726  methylmalonyl-CoA mutase, large subunit [KO:K01848] [EC:5.4.99.2]
Afer_1791  methylmalonyl-CoA mutase, large subunit [KO:K01848] [EC:5.4.99.2]
Afer_1084  FAD linked oxidase domain protein [KO:K00104] [EC:1.1.99.14]
Afer_1362  FAD linked oxidase domain protein [KO:K00104] [EC:1.1.99.14]
Afer_2002  FAD linked oxidase domain protein [KO:K00104] [EC:1.1.99.14]
Afer_1361  FAD linked oxidase domain protein [KO:K11472] [EC:1.1.99.14]
Afer_1360  protein of unknown function DUF224 cysteine-rich region domain protein [KO:K11473] [EC:1.1.99.14]
Afer_0119  Ribulose-bisphosphate carboxylase [KO:K01601] [EC:4.1.1.39]
Afer_0120  Ribulose-bisphosphate carboxylase [KO:K01602] [EC:4.1.1.39]
Afer_0242  glutamine synthetase catalytic region [KO:K01915] [EC:6.3.1.2]
Afer_0243  glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
Afer_1967  glutamine synthetase catalytic region [KO:K01915] [EC:6.3.1.2]
Afer_1805  Glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Afer_1119  Glycine dehydrogenase (decarboxylating) [KO:K00282] [EC:1.4.4.2]
Afer_1118  Glycine dehydrogenase (decarboxylating) [KO:K00283] [EC:1.4.4.2]
Afer_1120  glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
Afer_0293  pyridine nucleotide-disulphide oxidoreductase dimerization region [KO:K00382] [EC:1.8.1.4]
Afer_0717  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Afer_0826  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Afer_0973  glycine cleavage H-protein [KO:K02437]
Afer_1124  glycine cleavage system H protein [KO:K02437]
Afer_0974  glycine cleavage H-protein [KO:K02437]
Afer_1055  glycine cleavage H-protein [KO:K02437]
Afer_0572  glycerate kinase [KO:K00865] [EC:2.7.1.165]
Afer_0821  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
afo00010  Glycolysis / Gluconeogenesis
afo00020  Citrate cycle (TCA cycle)
afo00030  Pentose phosphate pathway
afo00071  Fatty acid degradation
afo00230  Purine metabolism
afo00250  Alanine, aspartate and glutamate metabolism
afo00260  Glycine, serine and threonine metabolism
afo00620  Pyruvate metabolism
afo00710  Carbon fixation in photosynthetic organisms
afo00750  Vitamin B6 metabolism
afo00910  Nitrogen metabolism
KO pathway
ko00630   

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