KEGG   PATHWAY: bmw00230
Entry
bmw00230                    Pathway                                
Name
Purine metabolism - Brucella melitensis NI
Class
Metabolism; Nucleotide metabolism
Pathway map
bmw00230  Purine metabolism
bmw00230

Module
bmw_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bmw00230]
bmw_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bmw00230]
bmw_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bmw00230]
bmw_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bmw00230]
bmw_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bmw00230]
bmw_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:bmw00230]
bmw_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:bmw00230]
Other DBs
GO: 0006163 0042278
Organism
Brucella melitensis NI [GN:bmw]
Gene
BMNI_I0056  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
BMNI_I1478  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
BMNI_I0460  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
BMNI_I0429  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
BMNI_I0706  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BMNI_I0825  phosphoribosylformylglycinamidine synthase II [KO:K23269] [EC:6.3.5.3]
BMNI_I0829  phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
BMNI_I0828  phosphoribosylformylglycinamidine synthase I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
BMNI_I0707  phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
BMNI_I1675  phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
BMNI_I1674  phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
BMNI_I0830  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BMNI_I0835  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BMNI_I1738  bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BMNI_I1485  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BMNI_I0872  stationary phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
BMNI_I1475  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BMNI_I1889  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
BMNI_II0333  inosine 5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
BMNI_I0690  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
BMNI_I0174  putative deoxyribonucleotide triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
BMNI_I1019  xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
BMNI_I0371  xanthine dehydrogenase, small subunit [KO:K13481] [EC:1.17.1.4]
BMNI_I0372  xanthine dehydrogenase [KO:K13482] [EC:1.17.1.4]
BMNI_II0343  GMP synthase [KO:K01951] [EC:6.3.5.2]
BMNI_I0376  guanine deaminase [KO:K01487] [EC:3.5.4.3]
BMNI_I0476  guanylate kinase [KO:K00942] [EC:2.7.4.8]
BMNI_II0302  ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
BMNI_I1017  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
BMNI_II0303  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
BMNI_I0862  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
BMNI_I0666  hypothetical protein [KO:K06952] [EC:3.1.3.89]
BMNI_I0653  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BMNI_II0637  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BMNI_I0747  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BMNI_I1619  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
BMNI_I0627  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
BMNI_II0607  adenine deaminase [KO:K01486] [EC:3.5.4.2]
BMNI_I1655  hypothetical protein [KO:K09769] [EC:3.1.4.16]
BMNI_I0720  adenylate kinase [KO:K00939] [EC:2.7.4.3]
BMNI_I1180  adenylate kinase [KO:K00939] [EC:2.7.4.3]
BMNI_I1039  nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
BMNI_I0191  sulfate adenylyltransferase, large subunit [KO:K00955] [EC:2.7.7.4 2.7.1.25]
BMNI_I0190  sulfate adenylyltransferase, small subunit [KO:K00957] [EC:2.7.7.4]
BMNI_I0518  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
BMNI_I0370  Polysaccharide deacetylase [KO:K16842] [EC:3.5.2.5]
BMNI_I0369  hypothetical protein [KO:K14977] [EC:3.5.3.26]
BMNI_I0517  ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
BMNI_I0297  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
BMNI_I1314  urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
BMNI_I0296  urease, beta subunit [KO:K01429] [EC:3.5.1.5]
BMNI_I1313  urease, beta subunit [KO:K01429] [EC:3.5.1.5]
BMNI_I0294  urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
BMNI_I1312  urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bmw00030  Pentose phosphate pathway
bmw00220  Arginine biosynthesis
bmw00250  Alanine, aspartate and glutamate metabolism
bmw00260  Glycine, serine and threonine metabolism
bmw00340  Histidine metabolism
bmw00630  Glyoxylate and dicarboxylate metabolism
bmw00730  Thiamine metabolism
bmw00740  Riboflavin metabolism
bmw00790  Folate biosynthesis
KO pathway
ko00230   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (54)   
   KEGG GENES (54)   
All databases (55)   

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