KEGG   PATHWAY: cds00290
Entry
cds00290                    Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Corynebacterium diphtheriae C7 (beta)
Class
Metabolism; Amino acid metabolism
Pathway map
cds00290  Valine, leucine and isoleucine biosynthesis
cds00290

Module
cds_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:cds00290]
cds_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:cds00290]
cds_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:cds00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Corynebacterium diphtheriae C7 (beta) [GN:cds]
Gene
CDC7B_1577  ilvA; threonine dehydratase [KO:K01754] [EC:4.3.1.19]
CDC7B_1049  leuC; isopropylmalate isomerase large subunit [KO:K01703] [EC:4.2.1.33 4.2.1.35]
CDC7B_1050  leuD; isopropylmalate isomerase small subunit [KO:K01704] [EC:4.2.1.33 4.2.1.35]
CDC7B_1025  leuB; 3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
CDC7B_1018  ilvB; acetolactate synthase 1 catalytic subunit [KO:K01652] [EC:2.2.1.6]
CDC7B_1019  ilvN; acetolactate synthase small subunit [KO:K01653] [EC:2.2.1.6]
CDC7B_1020  ilvC; ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
CDC7B_1016  ilvD; dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
CDC7B_1633  ilvE; branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
CDC7B_2123  alaT; alanine aminotransferase [KO:K14260] [EC:2.6.1.66 2.6.1.2]
CDC7B_0214  leuA; 2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
PMID:15292141
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
cds00260  Glycine, serine and threonine metabolism
cds00280  Valine, leucine and isoleucine degradation
cds00620  Pyruvate metabolism
KO pathway
ko00290   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG GENES (11)   
All databases (12)   

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