KEGG   PATHWAY: cdw00230
Entry
cdw00230                    Pathway                                
Name
Purine metabolism - Corynebacterium diphtheriae PW8
Class
Metabolism; Nucleotide metabolism
Pathway map
cdw00230  Purine metabolism
cdw00230

Module
cdw_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cdw00230]
cdw_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cdw00230]
cdw_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cdw00230]
cdw_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cdw00230]
cdw_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cdw00230]
Other DBs
GO: 0006163 0042278
Organism
Corynebacterium diphtheriae PW8 [GN:cdw]
Gene
CDPW8_1854  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
CDPW8_0870  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
CDPW8_1886  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
CDPW8_1902  purD; phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
CDPW8_0810  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
CDPW8_2026  purT; phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
CDPW8_2090  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
CDPW8_1885  purM; phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
CDPW8_0663  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
CDPW8_0664  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
CDPW8_1897  purC; phosphoribosylaminoimidazole-succinocarboxamidesynthase [KO:K01923] [EC:6.3.2.6]
CDPW8_1898  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
CDPW8_0811  bifunctionalphosphoribosylaminoimidazolecarboxam ide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
CDPW8_1343  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
CDPW8_1685  putative N-acetylglucosamine related protein [KO:K02566] [EC:3.1.3.5]
CDPW8_0286  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
CDPW8_1582  hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
CDPW8_2320  putative nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
CDPW8_1748  iunH; inosine-uridine preferring nucleoside hydrolase [KO:K25589] [EC:3.2.2.2 3.2.2.3]
CDPW8_1966  hpt; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
CDPW8_0578  guaB; inosine 5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
CDPW8_0579  inosine 5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
CDPW8_1776  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
CDPW8_1822  putative deoxyribonucleotide triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
CDPW8_1263  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
CDPW8_0594  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
CDPW8_1306  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
CDPW8_1839  nrdE; ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
CDPW8_1837  nrdF1; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
CDPW8_0453  anaerobic ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
CDPW8_1695  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
CDPW8_1342  rel; GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CDPW8_0887  putative exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CDPW8_0346  cya; adenylate cyclase [KO:K01768] [EC:4.6.1.1]
CDPW8_2031  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
CDPW8_0638  hypothetical protein [KO:K01488] [EC:3.5.4.4]
CDPW8_0540  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
CDPW8_1377  hypothetical protein [KO:K19710] [EC:2.7.7.53]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cdw00030  Pentose phosphate pathway
cdw00220  Arginine biosynthesis
cdw00250  Alanine, aspartate and glutamate metabolism
cdw00260  Glycine, serine and threonine metabolism
cdw00340  Histidine metabolism
cdw00630  Glyoxylate and dicarboxylate metabolism
cdw00730  Thiamine metabolism
cdw00740  Riboflavin metabolism
cdw00790  Folate biosynthesis
KO pathway
ko00230   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (38)   
   KEGG GENES (38)   
All databases (39)   

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