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Entry
ell00970                    Pathway                                

Name
Aminoacyl-tRNA biosynthesis - Escherichia coli W
Class
Genetic Information Processing; Translation
BRITE hierarchy
Pathway map
ell00970  Aminoacyl-tRNA biosynthesis
ell00970

Ortholog table
Module
ell_M00360  Aminoacyl-tRNA biosynthesis, prokaryotes [PATH:ell00970]
Organism
Escherichia coli W [GN:ell]
Gene
WFL_t23292  alaX; tRNA-Ala [KO:K14218]
WFL_t23294  alaW; tRNA-Ala [KO:K14218]
WFL_t23214  alaV; tRNA-Ala [KO:K14218]
WFL_t23358  alaT; tRNA-Ala [KO:K14218]
WFL_t23334  alaU; tRNA-Ala [KO:K14218]
WFL_t23224  argU; tRNA-Arg [KO:K14219]
WFL_t23348  argX; tRNA-Arg [KO:K14219]
WFL_t23306  argQ; tRNA-Arg [KO:K14219]
WFL_t23312  argV; tRNA-Arg [KO:K14219]
WFL_t23308  argZ; tRNA-Arg [KO:K14219]
WFL_t23310  argY; tRNA-Arg [KO:K14219]
WFL_t23290  argW; tRNA-Arg [KO:K14219]
WFL_t23280  asnT; tRNA-Asn [KO:K14220]
WFL_t23286  asnV; tRNA-Asn [KO:K14220]
WFL_t23282  asnW; tRNA-Asn [KO:K14220]
WFL_t23284  asnU; tRNA-Asn [KO:K14220]
WFL_t23216  aspU; tRNA-Asp [KO:K14221]
WFL_t23344  aspT; tRNA-Asp [KO:K14221]
WFL_t23218  aspV; tRNA-Asp [KO:K14221]
WFL_t23274  cysT; tRNA-Cys [KO:K14222]
WFL_t23226  glnX; tRNA-Gln [KO:K14223]
WFL_t23228  glnV; tRNA-Gln [KO:K14223]
WFL_t23232  glnW; tRNA-Gln [KO:K14223]
WFL_t23234  glnU; tRNA-Gln [KO:K14223]
WFL_t23304  gltW; tRNA-Glu [KO:K14224]
WFL_t23360  gltT; tRNA-Glu [KO:K14224]
WFL_t23342  gltU; tRNA-Glu [KO:K14224]
WFL_t23370  gltV; tRNA-Glu [KO:K14224]
WFL_t23366  glyT; tRNA-Gly [KO:K14225]
WFL_t23266  glyZ; tRNA-Gly [KO:K14225]
WFL_t23322  glyU; tRNA-Gly [KO:K14225]
WFL_t23276  glyW; tRNA-Gly [KO:K14225]
WFL_t23376  glyX; tRNA-Gly [KO:K14225]
WFL_t23374  glyV; tRNA-Gly [KO:K14225]
WFL_t23378  glyY; tRNA-Gly [KO:K14225]
WFL_t23350  hisR; tRNA-His [KO:K14226]
WFL_t23212  ileV; tRNA-Ile [KO:K14227]
WFL_t23336  ileU; tRNA-Ile [KO:K14227]
WFL_t23356  ileT; tRNA-Ile [KO:K14227]
WFL_t23272  leuZ; tRNA-Leu [KO:K14228]
WFL_t23236  leuW; tRNA-Leu [KO:K14228]
WFL_t23352  leuT; tRNA-Leu [KO:K14228]
WFL_t23386  leuQ; tRNA-Leu [KO:K14228]
WFL_t23382  leuV; tRNA-Leu [KO:K14228]
WFL_t23384  leuP; tRNA-Leu [KO:K14228]
WFL_t23330  leuU; tRNA-Leu [KO:K14228]
WFL_t23380  leuX; tRNA-Leu [KO:K14228]
WFL_t23240  lysT; tRNA-Lys [KO:K14229]
WFL_t23302  lysV; tRNA-Lys [KO:K14229]
WFL_t23244  lysW; tRNA-Lys [KO:K14229]
WFL_t23250  lysZ; tRNA-Lys [KO:K14229]
WFL_t23252  lysQ; tRNA-Lys [KO:K14229]
WFL_t23248  lysY; tRNA-Lys [KO:K14229]
WFL_t23316  metZ; tRNA-Met [KO:K14230]
WFL_t23328  metY; tRNA-Met [KO:K14230]
WFL_t23320  metV; tRNA-Met [KO:K14230]
WFL_t23318  metW; tRNA-Met [KO:K14230]
WFL_t23230  metU; tRNA-Met [KO:K14230]
WFL_t23238  metT; tRNA-Met [KO:K14230]
WFL_t23326  ileX; tRNA-Ile [KO:K14230]
WFL_t23324  pheV; tRNA-Phe [KO:K14231]
WFL_t23372  pheU; tRNA-Phe [KO:K14231]
WFL_t23338  proK; tRNA-Pro [KO:K14232]
WFL_t23354  proM; tRNA-Pro [KO:K14232]
WFL_t23288  proL; tRNA-Pro [KO:K14232]
WFL_t23254  serW; tRNA-Ser [KO:K14233]
WFL_t23258  serX; tRNA-Ser [KO:K14233]
WFL_t23314  serV; tRNA-Ser [KO:K14233]
WFL_t23278  serU; tRNA-Ser [KO:K14233]
WFL_t23256  serT; tRNA-Ser [KO:K14233]
WFL_t23368  thrT; tRNA-Thr [KO:K14234]
WFL_t23264  thrX; tRNA-Thr [KO:K14234]
WFL_t23362  thrU; tRNA-Thr [KO:K14234]
WFL_t23332  thrV; tRNA-Thr [KO:K14234]
WFL_t23220  thrW; tRNA-Thr [KO:K14234]
WFL_t23346  trpT; tRNA-Trp [KO:K14235]
WFL_t23364  tyrU; tRNA-Tyr [KO:K14236]
WFL_t23260  tyrV; tRNA-Tyr [KO:K14236]
WFL_t23262  tyrT; tRNA-Tyr [KO:K14236]
WFL_t23242  valT; tRNA-Val [KO:K14237]
WFL_t23246  valZ; tRNA-Val [KO:K14237]
WFL_t23300  valY; tRNA-Val [KO:K14237]
WFL_t23298  valX; tRNA-Val [KO:K14237]
WFL_t23296  valU; tRNA-Val [KO:K14237]
WFL_t23270  valW; tRNA-Val [KO:K14237]
WFL_t23268  valV; tRNA-Val [KO:K14237]
WFL_t23340  selC; tRNA-Sec [KO:K14238]
WFL_12900  gltX; glutamyl-tRNA synthetase [KO:K01885] [EC:6.1.1.17]
WFL_03600  glnS; glutaminyl-tRNA synthetase [KO:K01886] [EC:6.1.1.18]
WFL_14125  alaS; alanyl-tRNA synthetase [KO:K01872] [EC:6.1.1.7]
WFL_10020  aspS; aspartyl-tRNA synthetase [KO:K01876] [EC:6.1.1.12]
WFL_05065  asnS; asparaginyl-tRNA synthetase [KO:K01893] [EC:6.1.1.22]
WFL_18715  glyQ; glycyl-tRNA synthetase subunit alpha [KO:K01878] [EC:6.1.1.14]
WFL_18710  glyS; glycyl-tRNA synthetase subunit beta [KO:K01879] [EC:6.1.1.14]
WFL_09245  thrS; threonyl-tRNA synthetase [KO:K01868] [EC:6.1.1.3]
WFL_04875  serS; seryl-tRNA synthetase [KO:K01875] [EC:6.1.1.11]
WFL_18885  selA; selenocysteine synthase [KO:K01042] [EC:2.9.1.1]
WFL_02960  cysS; cysteinyl-tRNA synthetase [KO:K01883] [EC:6.1.1.16]
WFL_11330  metG; methionyl-tRNA synthetase [KO:K01874] [EC:6.1.1.10]
WFL_17360  fmt; methionyl-tRNA formyltransferase [KO:K00604] [EC:2.1.2.9]
WFL_22490  valS; valyl-tRNA synthetase [KO:K01873] [EC:6.1.1.9]
WFL_03460  leuS; leucyl-tRNA synthetase [KO:K01869] [EC:6.1.1.4]
WFL_00130  ileS; isoleucyl-tRNA synthetase [KO:K01870] [EC:6.1.1.5]
WFL_15350  lysS; lysyl-tRNA synthetase [KO:K04567] [EC:6.1.1.6]
WFL_21845  lysU; lysyl-tRNA synthetase [KO:K04567] [EC:6.1.1.6]
WFL_10070  argS; arginyl-tRNA synthetase [KO:K01887] [EC:6.1.1.19]
WFL_00945  proS; prolyl-tRNA synthetase [KO:K01881] [EC:6.1.1.15]
WFL_13415  hisS; histidyl-tRNA synthetase [KO:K01892] [EC:6.1.1.21]
WFL_09225  pheS; phenylalanyl-tRNA synthetase subunit alpha [KO:K01889] [EC:6.1.1.20]
WFL_09220  pheT; phenylalanyl-tRNA synthetase subunit beta [KO:K01890] [EC:6.1.1.20]
WFL_08840  tyrS; tyrosyl-tRNA synthetase [KO:K01866] [EC:6.1.1.1]
WFL_17775  trpS; tryptophanyl-tRNA synthetase [KO:K01867] [EC:6.1.1.2]
Compound
C00025  L-Glutamate
C00037  Glycine
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00073  L-Methionine
C00078  L-Tryptophan
C00079  L-Phenylalanine
C00082  L-Tyrosine
C00097  L-Cysteine
C00101  Tetrahydrofolate
C00123  L-Leucine
C00135  L-Histidine
C00148  L-Proline
C00152  L-Asparagine
C00183  L-Valine
C00188  L-Threonine
C00234  10-Formyltetrahydrofolate
C00407  L-Isoleucine
C00886  L-Alanyl-tRNA
C01005  O-Phospho-L-serine
C01931  L-Lysyl-tRNA
C02047  L-Leucyl-tRNA
C02163  L-Arginyl-tRNA(Arg)
C02282  Glutaminyl-tRNA
C02412  Glycyl-tRNA(Gly)
C02430  L-Methionyl-tRNA
C02553  L-Seryl-tRNA(Ser)
C02554  L-Valyl-tRNA(Val)
C02702  L-Prolyl-tRNA(Pro)
C02839  L-Tyrosyl-tRNA(Tyr)
C02984  L-Aspartyl-tRNA(Asp)
C02987  L-Glutamyl-tRNA(Glu)
C02988  L-Histidyl-tRNA(His)
C02992  L-Threonyl-tRNA(Thr)
C03125  L-Cysteinyl-tRNA(Cys)
C03127  L-Isoleucyl-tRNA(Ile)
C03294  N-Formylmethionyl-tRNA
C03402  L-Asparaginyl-tRNA(Asn)
C03511  L-Phenylalanyl-tRNA(Phe)
C03512  L-Tryptophanyl-tRNA(Trp)
C06112  L-Glutamyl-tRNA(Gln)
C06113  L-Aspartyl-tRNA(Asn)
C06481  L-Seryl-tRNA(Sec)
C06482  L-Selenocysteinyl-tRNA(Sec)
C16138  L-Pyrrolysine
C16638  O-Phosphoseryl-tRNA(Sec)
C17022  O-Phosphoseryl-tRNA(Cys)
C17027  L-Pyrrolysyl-tRNA(Pyl)
Reference
  Authors
Sheppard K, Yuan J, Hohn MJ, Jester B, Devine KM, Soll D
  Title
From one amino acid to another: tRNA-dependent amino acid biosynthesis.
  Journal
Nucleic Acids Res 36:1813-25 (2008)
DOI:10.1093/nar/gkn015
Reference
  Authors
Polycarpo C, Ambrogelly A, Berube A, Winbush SM, McCloskey JA, Crain PF, Wood JL, Soll D
  Title
An aminoacyl-tRNA synthetase that specifically activates pyrrolysine.
  Journal
Proc Natl Acad Sci U S A 101:12450-4 (2004)
DOI:10.1073/pnas.0405362101
KO pathway
ko00970   

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