KEGG   PATHWAY: ena00564
Entry
ena00564                    Pathway                                
Name
Glycerophospholipid metabolism - Escherichia coli NA114 (UPEC)
Class
Metabolism; Lipid metabolism
Pathway map
ena00564  Glycerophospholipid metabolism
ena00564

Module
ena_M00093  Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:ena00564]
Other DBs
GO: 0006650
Organism
Escherichia coli NA114 (UPEC) [GN:ena]
Gene
ECNA114_3761  gpsA; Glycerol-3-phosphate dehydrogenase [KO:K00057] [EC:1.1.1.94]
ECNA114_2333  glpA; Anaerobic glycerol-3-phosphate dehydrogenase subunit A [KO:K00111] [EC:1.1.5.3]
ECNA114_3533  glpD; Aerobic glycerol-3-phosphate dehydrogenase [KO:K00111] [EC:1.1.5.3]
ECNA114_2334  glpB; Anaerobic glycerol-3-phosphate dehydrogenase subunit B [KO:K00112] [EC:1.1.5.3]
ECNA114_2335  glpC; Anaerobic glycerol-3-phosphate dehydrogenase subunit C [KO:K00113]
ECNA114_4198  plsB; Glycerol-3-phosphate acyltransferase [KO:K00631] [EC:2.3.1.15]
ECNA114_3152  Putative transcriptional regulator LYSR-type [KO:K08591] [EC:2.3.1.275]
ECNA114_3105  1-acyl-sn-glycerol-3-phosphate acyltransferase [KO:K00655] [EC:2.3.1.51]
ECNA114_4199  dgkA; Diacylglycerol kinase [KO:K00901] [EC:2.7.1.107]
ECNA114_4112  pldA; Phospholipase A1 [KO:K01058] [EC:3.1.1.32 3.1.1.4]
ECNA114_4117  pldB; Lysophospholipase L2 [KO:K01048] [EC:3.1.1.5]
ECNA114_3555  ugpQ; Glycerophosphoryl diester phosphodiesterase [KO:K01126] [EC:3.1.4.46]
ECNA114_2331  glpQ; Glycerophosphoryl diester phosphodiesterase periplasmic protein [KO:K01126] [EC:3.1.4.46]
ECNA114_0224  Puataive Glycerol-3-phosphate cytidylyltransferase [KO:K00968] [EC:2.7.7.15]
ECNA114_2896  aas; 2-acylglycerophosphoethanolamine acyltransferase / Acyl-acyl-carrier-protein synthetase [KO:K05939] [EC:2.3.1.40 6.2.1.20]
ECNA114_2517  EutA ethanolamine utilization protein [KO:K04019]
ECNA114_2516  eutB; Heavy chain ethanolamine ammonia-lyase [KO:K03735] [EC:4.3.1.7]
ECNA114_2515  eutC; Light chain of ethanolamine ammonia-lyase [KO:K03736] [EC:4.3.1.7]
ECNA114_4057  cdh; CDP-diacylglycerol pyrophosphatase [KO:K01521] [EC:3.6.1.26]
ECNA114_0165  cdsA; CDP-diglyceride synthase [KO:K00981] [EC:2.7.7.41]
ECNA114_2658  pssA; CDP-diacylglycerol--serine O-phosphatidyltransferase [KO:K00998] [EC:2.7.8.8]
ECNA114_4379  psd; Phosphatidylserine decarboxylase [KO:K01613] [EC:4.1.1.65]
ECNA114_2003  pqsA; phosphatidylglycerophosphate synthetase [KO:K00995] [EC:2.7.8.5]
ECNA114_0395  pgpA; Phosphatidylglycerophosphatase A [KO:K01095] [EC:3.1.3.27]
ECNA114_1469  pgpB; Phosphatidylglycerophosphatase B [KO:K01096] [EC:3.1.3.27 3.6.1.75 3.1.3.4 3.6.1.27]
ECNA114_2633  yfhB; Hypothetical protein [KO:K18697] [EC:3.1.3.27]
ECNA114_1420  Cardiolipin synthetase [KO:K06131] [EC:2.7.8.-]
ECNA114_0721  ybhO; Cardiolipin synthetase [KO:K06131] [EC:2.7.8.-]
ECNA114_1101  Putative Cardiolipin synthetase [KO:K06132] [EC:2.7.8.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
ena00010  Glycolysis / Gluconeogenesis
ena00260  Glycine, serine and threonine metabolism
ena00561  Glycerolipid metabolism
ena00562  Inositol phosphate metabolism
ena00565  Ether lipid metabolism
ena00620  Pyruvate metabolism
KO pathway
ko00564   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG GENES (29)   
All databases (30)   

Download RDF
DBGET integrated database retrieval system