KEGG   PATHWAY: fca00250
Entry
fca00250                    Pathway                                
Name
Alanine, aspartate and glutamate metabolism - Felis catus (domestic cat)
Class
Metabolism; Amino acid metabolism
Pathway map
fca00250  Alanine, aspartate and glutamate metabolism
fca00250

Module
fca_M00027  GABA (gamma-Aminobutyrate) shunt [PATH:fca00250]
Other DBs
GO: 0006522 0006531 0006536
Organism
Felis catus (domestic cat) [GN:fca]
Gene
101085155  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
101099457  GOT1L1; putative aspartate aminotransferase, cytoplasmic 2 [KO:K14454] [EC:2.6.1.1]
101090160  GOT2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
101100683  IL4I1; L-amino-acid oxidase isoform X2 [KO:K03334] [EC:1.4.3.2]
111561629  L-amino-acid oxidase-like [KO:K03334] [EC:1.4.3.2]
101081048  DDO; D-aspartate oxidase isoform X1 [KO:K00272] [EC:1.4.3.1]
101087268  ASRGL1; isoaspartyl peptidase/L-asparaginase [KO:K13051] [EC:3.5.1.1 3.4.19.5]
101096050  ASNS; asparagine synthetase [glutamine-hydrolyzing] [KO:K01953] [EC:6.3.5.4]
101093040  NIT2; omega-amidase NIT2 isoform X1 [KO:K13566] [EC:3.5.1.3]
101088131  GPT2; alanine aminotransferase 2 [KO:K00814] [EC:2.6.1.2]
101097207  GPT; alanine aminotransferase 1 isoform X1 [KO:K00814] [EC:2.6.1.2]
727692  AGXT; serine--pyruvate aminotransferase, mitochondrial precursor [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
101097947  AGXT2; LOW QUALITY PROTEIN: alanine--glyoxylate aminotransferase 2, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
101097525  ASS1; argininosuccinate synthase isoform X1 [KO:K01940] [EC:6.3.4.5]
101101529  ASL; argininosuccinate lyase [KO:K01755] [EC:4.3.2.1]
101087673  ADSS1; adenylosuccinate synthetase isozyme 1 isoform X2 [KO:K01939] [EC:6.3.4.4]
101092076  ADSS2; adenylosuccinate synthetase isozyme 2 isoform X2 [KO:K01939] [EC:6.3.4.4]
101085644  ADSL; adenylosuccinate lyase isoform X1 [KO:K01756] [EC:4.3.2.2]
101083676  NAT8L; N-acetylaspartate synthetase [KO:K18309] [EC:2.3.1.17]
101097740  RIMKLB; beta-citrylglutamate synthase B [KO:K18310] [EC:6.3.1.17 6.3.2.41]
101099388  RIMKLA; N-acetylaspartylglutamate synthase A isoform X1 [KO:K18311] [EC:6.3.2.41 6.3.2.42]
101089641  FOLH1B; putative N-acetylated-alpha-linked acidic dipeptidase isoform X2 [KO:K14592] [EC:3.4.17.21]
101094220  ASPA; aspartoacylase isoform X1 [KO:K01437] [EC:3.5.1.15]
493699  GAD1; glutamate decarboxylase 1 [KO:K01580] [EC:4.1.1.15]
101082244  GAD2; glutamate decarboxylase 2 [KO:K01580] [EC:4.1.1.15]
101089064  ABAT; 4-aminobutyrate aminotransferase, mitochondrial [KO:K13524] [EC:2.6.1.19 2.6.1.22]
101088238  ALDH5A1; succinate-semialdehyde dehydrogenase, mitochondrial isoform X1 [KO:K00139] [EC:1.2.1.24]
101090049  GLUD1; glutamate dehydrogenase 1, mitochondrial [KO:K00261] [EC:1.4.1.3]
101089025  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
101093325  GLUL; glutamine synthetase isoform X1 [KO:K01915] [EC:6.3.1.2]
101091102  CAD; CAD protein isoform X1 [KO:K11540] [EC:6.3.5.5 2.1.3.2 3.5.2.3]
101100228  GLS2; glutaminase liver isoform, mitochondrial isoform X1 [KO:K01425] [EC:3.5.1.2]
101080395  GLS; glutaminase kidney isoform, mitochondrial isoform X1 [KO:K01425] [EC:3.5.1.2]
101099824  CPS1; carbamoyl-phosphate synthase [ammonia], mitochondrial [KO:K01948] [EC:6.3.4.16]
101084509  GFPT2; glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 [KO:K00820] [EC:2.6.1.16]
101093346  GFPT1; glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 isoform X2 [KO:K00820] [EC:2.6.1.16]
101084957  PPAT; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
Compound
C00014  Ammonia
C00022  Pyruvate
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00036  Oxaloacetate
C00041  L-Alanine
C00042  Succinate
C00049  L-Aspartate
C00064  L-Glutamine
C00122  Fumarate
C00152  L-Asparagine
C00158  Citrate
C00169  Carbamoyl phosphate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00352  D-Glucosamine 6-phosphate
C00402  D-Aspartate
C00438  N-Carbamoyl-L-aspartate
C00940  2-Oxoglutaramate
C01042  N-Acetyl-L-aspartate
C02362  2-Oxosuccinamate
C03090  5-Phosphoribosylamine
C03406  N-(L-Arginino)succinate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03912  (S)-1-Pyrroline-5-carboxylate
C12270  N-Acetylaspartylglutamate
C20775  beta-Citryl-L-glutamate
C20776  N-Acetylaspartylglutamylglutamate
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
PMID:9687539
  Authors
Wu G
  Title
Intestinal mucosal amino acid catabolism.
  Journal
J Nutr 128:1249-52 (1998)
DOI:10.1093/jn/128.8.1249
Related
pathway
fca00010  Glycolysis / Gluconeogenesis
fca00020  Citrate cycle (TCA cycle)
fca00220  Arginine biosynthesis
fca00230  Purine metabolism
fca00240  Pyrimidine metabolism
fca00260  Glycine, serine and threonine metabolism
fca00330  Arginine and proline metabolism
fca00340  Histidine metabolism
fca00410  beta-Alanine metabolism
fca00470  D-Amino acid metabolism
fca00480  Glutathione metabolism
fca00520  Amino sugar and nucleotide sugar metabolism
fca00620  Pyruvate metabolism
fca00630  Glyoxylate and dicarboxylate metabolism
fca00650  Butanoate metabolism
fca00760  Nicotinate and nicotinamide metabolism
fca00770  Pantothenate and CoA biosynthesis
fca00860  Porphyrin metabolism
fca00910  Nitrogen metabolism
KO pathway
ko00250   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (37)   
   KEGG GENES (37)   
All databases (38)   

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