KEGG PATHWAY: mtb00190

PATHWAY: mtb00190

Entry

mtb00190 Pathway

Name

Oxidative phosphorylation - Mycobacterium tuberculosis KZN 1435

Class

Metabolism; Energy metabolism

Pathway map

mtb00190

Oxidative phosphorylation

Module

mtb_M00149	Succinate dehydrogenase, prokaryotes [PATH:mtb00190]
mtb_M00150	Fumarate reductase, prokaryotes [PATH:mtb00190]
mtb_M00151	Cytochrome bc1 complex respiratory unit [PATH:mtb00190]
mtb_M00153	Cytochrome d ubiquinol oxidase [PATH:mtb00190]
mtb_M00155	Cytochrome c oxidase, prokaryotes [PATH:mtb00190]
mtb_M00157	F-type ATPase, prokaryotes and chloroplasts [PATH:mtb00190]

Organism

Mycobacterium tuberculosis KZN 1435 [GN:mtb]

Gene

TBMG_03188	NADH dehydrogenase subunit A; K00330 NADH-quinone oxidoreductase subunit A [EC:1.6.5.3] [KO:K00330] [EC:1.6.5.3]
TBMG_03189	NADH dehydrogenase subunit B; K00331 NADH-quinone oxidoreductase subunit B [EC:1.6.5.3] [KO:K00331] [EC:1.6.5.3]
TBMG_03190	NADH dehydrogenase subunit C; K00332 NADH-quinone oxidoreductase subunit C [EC:1.6.5.3] [KO:K00332] [EC:1.6.5.3]
TBMG_03191	NADH dehydrogenase subunit D; K00333 NADH-quinone oxidoreductase subunit D [EC:1.6.5.3] [KO:K00333] [EC:1.6.5.3]
TBMG_03192	NADH dehydrogenase subunit E; K00334 NADH-quinone oxidoreductase subunit E [EC:1.6.5.3] [KO:K00334] [EC:1.6.5.3]
TBMG_03195	NADH dehydrogenase subunit H; K00337 NADH-quinone oxidoreductase subunit H [EC:1.6.5.3] [KO:K00337] [EC:1.6.5.3]
TBMG_03196	NADH dehydrogenase subunit I; K00338 NADH-quinone oxidoreductase subunit I [EC:1.6.5.3] [KO:K00338] [EC:1.6.5.3]
TBMG_03197	NADH dehydrogenase subunit J; K00339 NADH-quinone oxidoreductase subunit J [EC:1.6.5.3] [KO:K00339] [EC:1.6.5.3]
TBMG_03198	NADH dehydrogenase subunit K; K00340 NADH-quinone oxidoreductase subunit K [EC:1.6.5.3] [KO:K00340] [EC:1.6.5.3]
TBMG_03199	NADH dehydrogenase subunit L; K00341 NADH-quinone oxidoreductase subunit L [EC:1.6.5.3] [KO:K00341] [EC:1.6.5.3]
TBMG_03200	NADH dehydrogenase subunit M; K00342 NADH-quinone oxidoreductase subunit M [EC:1.6.5.3] [KO:K00342] [EC:1.6.5.3]
TBMG_03201	NADH dehydrogenase subunit N; K00343 NADH-quinone oxidoreductase subunit N [EC:1.6.5.3] [KO:K00343] [EC:1.6.5.3]
TBMG_02140	NADH dehydrogenase ndh; K03885 NADH dehydrogenase [EC:1.6.99.3] [KO:K03885] [EC:1.6.99.3]
TBMG_00392	membrane NADH dehydrogenase ndhA; K03885 NADH dehydrogenase [EC:1.6.99.3] [KO:K03885] [EC:1.6.99.3]
TBMG_02182	dehydrogenase; K03885 NADH dehydrogenase [EC:1.6.99.3] [KO:K03885] [EC:1.6.99.3]
TBMG_00250	sdhA; succinate dehydrogenase flavoprotein subunit [KO:K00239] [EC:1.3.5.4 1.3.5.1]
TBMG_03367	sdhA; succinate dehydrogenase flavoprotein subunit [KO:K00239] [EC:1.3.5.4 1.3.5.1]
TBMG_00249	fumarate reductase iron-sulfur subunit; K00240 succinate dehydrogenase / fumarate reductase, iron-sulfur subunit [EC:1.3.5.1 1.3.5.4] [KO:K00240] [EC:1.3.5.4 1.3.5.1]
TBMG_03368	sdhB; succinate dehydrogenase iron-sulfur subunit [KO:K00240] [EC:1.3.5.4 1.3.5.1]
TBMG_03365	succinate dehydrogenase cytochrome B-556 subunit sdhC; K00241 succinate dehydrogenase / fumarate reductase, cytochrome b subunit [KO:K00241]
TBMG_03366	succinate dehydrogenase hydrophobic membrane anchor subunit sdhD; K00242 succinate dehydrogenase / fumarate reductase, membrane anchor subunit [KO:K00242]
TBMG_02426	fumarate reductase flavoprotein subunit; K00244 fumarate reductase flavoprotein subunit [EC:1.3.5.4] [KO:K00244] [EC:1.3.5.4]
TBMG_02425	fumarate reductase iron-sulfur subunit frdB; K00245 fumarate reductase iron-sulfur subunit [EC:1.3.5.4] [KO:K00245] [EC:1.3.5.4]
TBMG_02424	fumarate reductase subunit C; K00246 fumarate reductase subunit C [KO:K00246]
TBMG_02423	fumarate reductase subunit D; K00247 fumarate reductase subunit D [KO:K00247]
TBMG_01787	ubiquinol-cytochrome C reductase qcrC cytochrome C subunit; K03889 ubiquinol-cytochrome c reductase cytochrome c subunit [KO:K03889]
TBMG_01786	Rieske iron-sulfur protein qcrA; K03890 ubiquinol-cytochrome c reductase iron-sulfur subunit [KO:K03890]
TBMG_01785	ubiquinol-cytochrome C reductase qcrB cytochrome B subunit; K03891 ubiquinol-cytochrome c reductase cytochrome b subunit [KO:K03891]
TBMG_04063	protoheme IX farnesyltransferase; K02301 protoheme IX farnesyltransferase [EC:2.5.1.-] [KO:K02301] [EC:2.5.1.-]
TBMG_01788	cytochrome C oxidase subunit III ctaE; K02276 cytochrome c oxidase subunit III [EC:1.9.3.1] [KO:K02276] [EC:1.9.3.1]
TBMG_00926	cytochrome C oxidase polypeptide I ctaD; K02274 cytochrome c oxidase subunit I [EC:1.9.3.1] [KO:K02274] [EC:1.9.3.1]
TBMG_01781	transmembrane cytochrome C oxidase subunit II ctaC; K02275 cytochrome c oxidase subunit II [EC:1.9.3.1] [KO:K02275] [EC:1.9.3.1]
TBMG_02526	antibiotic-transport membrane ABC transporter; K02259 cytochrome c oxidase assembly protein subunit 15 [KO:K02259]
TBMG_02371	membrane cytochrome D ubiquinol oxidase subunit I cydA; K00425 cytochrome d ubiquinol oxidase subunit I [EC:1.10.3.-] [KO:K00425] [EC:1.10.3.-]
TBMG_02372	membrane cytochrome D ubiquinol oxidase subunit II cydB; K00426 cytochrome d ubiquinol oxidase subunit II [EC:1.10.3.-] [KO:K00426] [EC:1.10.3.-]
TBMG_02672	ATP synthase F0F1 subunit alpha; K02111 F-type H+-transporting ATPase subunit alpha [EC:3.6.3.14] [KO:K02111] [EC:3.6.3.14]
TBMG_02670	ATP synthase F0F1 subunit beta; K02112 F-type H+-transporting ATPase subunit beta [EC:3.6.3.14] [KO:K02112] [EC:3.6.3.14]
TBMG_02671	ATP synthase F0F1 subunit gamma; K02115 F-type H+-transporting ATPase subunit gamma [KO:K02115]
TBMG_02673	ATP synthase F0F1 subunit delta; K02109 F-type H+-transporting ATPase subunit b K02113 F-type H+-transporting ATPase subunit delta [KO:K02109 K02113]
TBMG_02669	atpC; ATP synthase F0F1 subunit epsilon [KO:K02114]
TBMG_02676	ATP synthase F0F1 subunit A; K02108 F-type H+-transporting ATPase subunit a [KO:K02108]
TBMG_02674	ATP synthase F0F1 subunit B; K02109 F-type H+-transporting ATPase subunit b [KO:K02109]
TBMG_02675	ATP synthase F0F1 subunit C; K02110 F-type H+-transporting ATPase subunit c [KO:K02110]
TBMG_03665	inorganic pyrophosphatase ppa; K01507 inorganic pyrophosphatase [EC:3.6.1.1] [KO:K01507] [EC:3.6.1.1]
TBMG_00985	polyphosphate kinase; K00937 polyphosphate kinase [EC:2.7.4.1] [KO:K00937] [EC:2.7.4.1]

Compound

C00001	H2O
C00002	ATP
C00003	NAD+
C00004	NADH
C00007	Oxygen
C00008	ADP
C00009	Orthophosphate
C00013	Diphosphate
C00042	Succinate
C00061	FMN
C00080	H+
C00122	Fumarate
C00390	Ubiquinol
C00399	Ubiquinone
C00524	Cytochrome c
C00536	Triphosphate

Reference

PMID:16469879

Authors

Sazanov LA, Hinchliffe P.

Title

Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus.

Journal

Science 311:1430-6 (2006)

Reference

PMID:16584177

Authors

Hinchliffe P, Carroll J, Sazanov LA.

Title

Identification of a novel subunit of respiratory complex I from Thermus thermophilus.

Journal

Biochemistry 45:4413-20 (2006)

KO pathway

ko00190

All links

Pathway (7)   
   KEGG MODULE (6)   
   BioSystems (1)   
Gene (45)   
   KEGG GENES (45)   
All databases (52)   

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