KEGG   PATHWAY: pfs00630
Entry
pfs00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Pseudomonas fluorescens SBW25
Class
Metabolism; Carbohydrate metabolism
Pathway map
pfs00630  Glyoxylate and dicarboxylate metabolism
pfs00630

Module
pfs_M00621  Glycine cleavage system [PATH:pfs00630]
Other DBs
GO: 0046487 0043648
Organism
Pseudomonas fluorescens SBW25 [GN:pfs]
Gene
PFLU_3817  Isocitrase (EC (Isocitratase) (Isocitrate lyase) [KO:K01637] [EC:4.1.3.1]
PFLU_2290  Putative acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
PFLU_3213  Acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
PFLU_5244  Acetyl-coenzyme A synthetase (AcCoA synthetase) (Acs) (EC (Acetate--CoA ligase) (Acyl-activating enzyme) [KO:K01895] [EC:6.2.1.1]
PFLU_4766  Acetyl-coenzyme A synthetase (AcCoA synthetase) (Acs) (EC (Acetate--CoA ligase) (Acyl-activating enzyme) [KO:K01895] [EC:6.2.1.1]
PFLU_5623  glcB; Malate synthase G (EC [KO:K01638] [EC:2.3.3.9]
PFLU_1815  gltA; Citrate synthase [KO:K01647] [EC:2.3.3.1]
PFLU_1542  acnA; Aconitate hydratase (Aconitase) (EC [KO:K01681] [EC:4.2.1.3]
PFLU_3489  Aconitate hydratase B (EC (EC (2-methylisocitrate dehydratase) [KO:K01682] [EC:4.2.1.3 4.2.1.99]
PFLU_3028  Putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
PFLU_3297  Putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
PFLU_3526  Putative 3-ketoacyl-CoA thiolase (EC [KO:K00626] [EC:2.3.1.9]
PFLU_0655  Putative thiolase [KO:K00626] [EC:2.3.1.9]
PFLU_4662  Putative acetyl CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
PFLU_2150  Putative acetyl-CoA transferase [KO:K00626] [EC:2.3.1.9]
PFLU_4832  MaoC-like domain-containing protein [KO:K17865] [EC:4.2.1.55]
PFLU_0071  katE; Catalase (EC [KO:K03781] [EC:1.11.1.6]
PFLU_5339  katB; Catalase (EC [KO:K03781] [EC:1.11.1.6]
PFLU_5500  katA; Catalase (EC [KO:K03781] [EC:1.11.1.6]
PFLU_3897  Catalase-related peroxidase (EC [KO:K03781] [EC:1.11.1.6]
PFLU_4037  Putative 2-hydroxyacid dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
PFLU_0968  tkrA; 2-ketogluconate reductase (EC [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
PFLU_0920  hprA; Glycerate dehydrogenase (EC [KO:K00018] [EC:1.1.1.29]
PFLU_0046  Putative hydrolase [KO:K01091] [EC:3.1.3.18]
PFLU_4235  Putative phosphoglycolate phosphatase (EC [KO:K01091] [EC:3.1.3.18]
PFLU_5562  Phosphoglycolate phosphatase (PGP) (PGPase) (EC [KO:K01091] [EC:3.1.3.18]
PFLU_4712  Putative hydrolase [KO:K01091] [EC:3.1.3.18]
PFLU_0348  glnA; Glutamine synthetase (EC [KO:K01915] [EC:6.3.1.2]
PFLU_1514  Putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PFLU_2163  Putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PFLU_2323  Putative glutamine synthetase III [KO:K01915] [EC:6.3.1.2]
PFLU_5847  Putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PFLU_5849  Putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PFLU_3065  Putative glutamine synthetase [KO:K01915] [EC:6.3.1.2]
PFLU_5330  glyA; Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC [KO:K00600] [EC:2.1.2.1]
PFLU_5652  glyA; Serine hydroxymethyltransferase (SHMT) (Serine methylase) (EC [KO:K00600] [EC:2.1.2.1]
PFLU_4897  Glycine dehydrogenase (decarboxylating) (EC (Glycine cleavage system P-protein) (Glycine decarboxylase) (Glycine dehydrogenase (aminomethyl-transferring)) [KO:K00281] [EC:1.4.4.2]
PFLU_5874  gcvT; Aminomethyltransferase (EC (Glycine cleavage system T protein) [KO:K00605] [EC:2.1.2.10]
PFLU_4899  Glycine cleavage system T protein (EC [KO:K00605] [EC:2.1.2.10]
PFLU_2330  Putative aminomethyltransferase-like protein [KO:K00605] [EC:2.1.2.10]
PFLU_2333  Putative aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
PFLU_1822  lpd; Dihydrolipoyl dehydrogenase (EC [KO:K00382] [EC:1.8.1.4]
PFLU_3967  Dihydrolipoyl dehydrogenase (EC [KO:K00382] [EC:1.8.1.4]
PFLU_5873  gcvH; Glycine cleavage system H protein [KO:K02437]
PFLU_4896  Glycine cleavage system H protein [KO:K02437]
PFLU_1803  gcl; Glyoxylate carboligase (EC [KO:K01608] [EC:4.1.1.47]
PFLU_1802  hyi; Hydroxypyruvate isomerase (EC [KO:K01816] [EC:5.3.1.22]
PFLU_2384  AP_endonuc_2 domain-containing protein [KO:K01816] [EC:5.3.1.22]
PFLU_1801  glxR; 2-hydroxy-3-oxopropionate reductase (EC [KO:K00042] [EC:1.1.1.60]
PFLU_3004  Glycerate kinase (EC [KO:K00865] [EC:2.7.1.165]
PFLU_1800  Putative hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
PFLU_4038  D-malate dehydrogenase [decarboxylating] (EC [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
PFLU_4836  2-dehydro-3-deoxy-phosphogluconate aldolase (EC [KO:K01625] [EC:4.1.2.14 4.1.3.42]
PFLU_5199  Kynurenine formamidase (KFA) (KFase) (EC (Arylformamidase) (N-formylkynurenine formamidase) (FKF) [KO:K07130] [EC:3.5.1.9]
PFLU_4938  Formyltetrahydrofolate deformylase (EC (Formyl-FH(4) hydrolase) [KO:K01433] [EC:3.5.1.10]
PFLU_5647  purU; Formyltetrahydrofolate deformylase (EC (Formyl-FH(4) hydrolase) [KO:K01433] [EC:3.5.1.10]
PFLU_2321  purU1; Formyltetrahydrofolate deformylase (EC (Formyl-FH(4) hydrolase) [KO:K01433] [EC:3.5.1.10]
PFLU_2332  purU2; Formyltetrahydrofolate deformylase (EC (Formyl-FH(4) hydrolase) [KO:K01433] [EC:3.5.1.10]
PFLU_2534  fmdA; Formamidase (EC [KO:K01455] [EC:3.5.1.49]
PFLU_0370  Putative hydrolase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
pfs00010  Glycolysis / Gluconeogenesis
pfs00020  Citrate cycle (TCA cycle)
pfs00030  Pentose phosphate pathway
pfs00053  Ascorbate and aldarate metabolism
pfs00071  Fatty acid degradation
pfs00230  Purine metabolism
pfs00250  Alanine, aspartate and glutamate metabolism
pfs00260  Glycine, serine and threonine metabolism
pfs00620  Pyruvate metabolism
pfs00750  Vitamin B6 metabolism
pfs00910  Nitrogen metabolism
KO pathway
ko00630   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (60)   
   KEGG GENES (60)   
All databases (61)   

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