KEGG   PATHWAY: pps00330
Entry
pps00330                    Pathway                                
Name
Arginine and proline metabolism - Pan paniscus (bonobo)
Class
Metabolism; Amino acid metabolism
Pathway map
pps00330  Arginine and proline metabolism
pps00330

Module
pps_M00015  Proline biosynthesis, glutamate => proline [PATH:pps00330]
pps_M00047  Creatine pathway [PATH:pps00330]
pps_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:pps00330]
pps_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:pps00330]
pps_M00970  Proline degradation, proline => glutamate [PATH:pps00330]
pps_M00972  Proline metabolism [PATH:pps00330]
Other DBs
GO: 0006525 0006560
Organism
Pan paniscus (bonobo) [GN:pps]
Gene
100982293  GATM; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
100973784  GAMT; guanidinoacetate N-methyltransferase isoform X2 [KO:K00542] [EC:2.1.1.2]
100971845  CKMT2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
100994997  CKB; creatine kinase B-type isoform X1 [KO:K00933] [EC:2.7.3.2]
117976014  creatine kinase U-type, mitochondrial-like isoform X1 [KO:K00933] [EC:2.7.3.2]
100991599  CKMT1A; creatine kinase U-type, mitochondrial isoform X1 [KO:K00933] [EC:2.7.3.2]
100993597  CKM; creatine kinase M-type [KO:K27382] [EC:2.7.3.2]
100984972  AZIN2; antizyme inhibitor 2 [KO:K01583] [EC:4.1.1.19]
100993312  ODC1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
100993236  spermidine synthase [KO:K00797] [EC:2.5.1.16]
100981225  SRM; spermidine synthase [KO:K00797] [EC:2.5.1.16]
100974711  LOW QUALITY PROTEIN: spermine synthase [KO:K00802] [EC:2.5.1.22]
100976750  spermine synthase-like [KO:K00802] [EC:2.5.1.22]
100989256  SMS; spermine synthase isoform X1 [KO:K00802] [EC:2.5.1.22]
100967811  AMD1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
100973977  AOC1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
100983105  SMOX; spermine oxidase isoform X2 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
100981893  ALDH1B1; aldehyde dehydrogenase X, mitochondrial [KO:K00128] [EC:1.2.1.3]
100969562  ALDH3A2; aldehyde dehydrogenase family 3 member A2 isoform X2 [KO:K00128] [EC:1.2.1.3]
100970208  ALDH2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
100970731  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
100970644  LOW QUALITY PROTEIN: alpha-aminoadipic semialdehyde dehydrogenase-like [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
100993750  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
100970514  CNDP1; beta-Ala-His dipeptidase isoform X8 [KO:K05604] [EC:3.4.13.20]
117974220  CNDP2; cytosolic non-specific dipeptidase isoform X1 [KO:K08660] [EC:3.4.13.18]
100992842  CARNS1; carnosine synthase 1 isoform X1 [KO:K14755] [EC:6.3.2.11]
100977863  SAT2; diamine acetyltransferase 2 isoform X1 [KO:K00657] [EC:2.3.1.57]
100992425  SAT1; diamine acetyltransferase 1 isoform X2 [KO:K00657] [EC:2.3.1.57]
100984839  MAOB; amine oxidase [flavin-containing] B [KO:K00274] [EC:1.4.3.4]
100985360  MAOA; amine oxidase [flavin-containing] A [KO:K00274] [EC:1.4.3.4]
100992228  AGMAT; agmatinase, mitochondrial [KO:K27001] [EC:3.5.3.- 3.5.3.7 3.5.3.17]
100996089  NOS1; nitric oxide synthase, brain isoform X1 [KO:K13240] [EC:1.14.13.39]
100976546  NOS2; nitric oxide synthase, inducible isoform X1 [KO:K13241] [EC:1.14.13.39]
100974638  NOS3; nitric oxide synthase, endothelial isoform X1 [KO:K13242] [EC:1.14.13.39]
100974594  ARG2; arginase-2, mitochondrial isoform X1 [KO:K01476] [EC:3.5.3.1]
100972438  ARG1; arginase-1 [KO:K01476] [EC:3.5.3.1]
100988018  OAT; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
100969152  PYCR2; pyrroline-5-carboxylate reductase 2 isoform X1 [KO:K00286] [EC:1.5.1.2]
100976354  PYCR3; pyrroline-5-carboxylate reductase 3 [KO:K00286] [EC:1.5.1.2]
100989452  PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial isoform X1 [KO:K00286] [EC:1.5.1.2]
100987322  proline dehydrogenase 1, mitochondrial isoform X1 [KO:K00318] [EC:1.5.5.2]
100994912  uncharacterized protein LOC100994912 isoform X1 [KO:K00318] [EC:1.5.5.2]
100984082  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
100969924  ALDH18A1; delta-1-pyrroline-5-carboxylate synthase isoform X2 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
100980929  LAP3; cytosol aminopeptidase isoform X1 [KO:K11142] [EC:3.4.11.1 3.4.11.5]
100976439  P4HA3; prolyl 4-hydroxylase subunit alpha-3 isoform X1 [KO:K00472] [EC:1.14.11.2]
100993331  P4HA2; prolyl 4-hydroxylase subunit alpha-2 isoform X2 [KO:K00472] [EC:1.14.11.2]
100992298  P4HA1; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
100988900  PRODH2; hydroxyproline dehydrogenase isoform X1 [KO:K11394] [EC:1.5.5.3]
100991554  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
100973276  GOT1L1; putative aspartate aminotransferase, cytoplasmic 2 [KO:K14454] [EC:2.6.1.1]
100992238  GOT2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
103782784  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1 [KO:K18123] [EC:4.1.3.16]
100989465  DAO; D-amino-acid oxidase [KO:K00273] [EC:1.4.3.3]
100973980  L3HYPDH; trans-3-hydroxy-L-proline dehydratase isoform X1 [KO:K18384] [EC:4.2.1.77]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
pps00020  Citrate cycle (TCA cycle)
pps00220  Arginine biosynthesis
pps00250  Alanine, aspartate and glutamate metabolism
pps00260  Glycine, serine and threonine metabolism
pps00270  Cysteine and methionine metabolism
pps00310  Lysine degradation
pps00410  beta-Alanine metabolism
pps00470  D-Amino acid metabolism
pps00480  Glutathione metabolism
pps00630  Glyoxylate and dicarboxylate metabolism
pps00650  Butanoate metabolism
pps00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (55)   
   KEGG GENES (55)   
All databases (56)   

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