KEGG   PATHWAY: req00230Help
Entry
req00230                    Pathway                                

Name
Purine metabolism - Rhodococcus hoagii
Class
Metabolism; Nucleotide metabolism
BRITE hierarchy
Pathway map
req00230  Purine metabolism
req00230

Ortholog table
Module
req_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:req00230]
req_M00048  Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:req00230]
req_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:req00230]
req_M00050  Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:req00230]
Other DBs
BSID: 179587
GO: 0042278
Organism
Rhodococcus hoagii [GN:req]
Gene
REQ_24660  putative NUDIX superfamily hydrolase [KO:K01515] [EC:3.6.1.13]
REQ_32340  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
REQ_12530  prsA; ribose-phosphate diphosphokinase PrsA [KO:K00948] [EC:2.7.6.1]
REQ_08400  purF; amidophosphoribosyltransferase PurF [KO:K00764] [EC:2.4.2.14]
REQ_07860  purD; phosphoribosylamine-glycine ligase PurD [KO:K01945] [EC:6.3.4.13]
REQ_11400  purN; secreted phosphoribosylglycinamide formyltransferase PurN [KO:K11175] [EC:2.1.2.2]
REQ_39360  purT; phosphoribosylglycinamide formyltransferase PurT [KO:K08289] [EC:2.1.2.2]
REQ_08260  purS; phosphoribosylformylglycinamidine synthase PurS [KO:K01952] [EC:6.3.5.3]
REQ_08270  purQ; phosphoribosylformylglycinamidine synthase I PurQ [KO:K01952] [EC:6.3.5.3]
REQ_08350  purL; phosphoribosylformylglycinamidine synthase II PurL [KO:K01952] [EC:6.3.5.3]
REQ_08410  purM; phosphoribosylformylglycinamidine cyclo-ligase PurM [KO:K01933] [EC:6.3.3.1]
REQ_33770  purK; phosphoribosylaminoimidazole carboxylase PurK [KO:K01589] [EC:6.3.4.18]
REQ_33760  purE; phosphoribosylaminoimidazole carboxylase PurE [KO:K01588] [EC:5.4.99.18]
REQ_08080  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase PurC [KO:K01923] [EC:6.3.2.6]
REQ_07890  purB; adenylosuccinate lyase PurB [KO:K01756] [EC:4.3.2.2]
REQ_11410  purHJ; phosphoribosylphosphoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurHJ [KO:K00602] [EC:3.5.4.10 2.1.2.3]
REQ_20930  putative phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
REQ_02610  putative secreted 5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
REQ_34200  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
REQ_05810  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
REQ_24270  guaB1; IMP dehydrogenase GuaB1 [KO:K00088] [EC:1.1.1.205]
REQ_34920  putative IMP dehydrogenase/GMP reductase [KO:K00088] [EC:1.1.1.205]
REQ_34930  guaB; IMP dehydrogenase GuaB [KO:K00088] [EC:1.1.1.205]
REQ_29870  ndkA; nucleoside-diphosphate kinase NdkA [KO:K00940] [EC:2.7.4.6]
REQ_17910  Ham1 family protein [KO:K02428] [EC:3.6.1.66]
REQ_12570  putative NTP pyrophosphohydrolase [KO:K02428] [EC:3.6.1.66]
REQ_02730  aldehyde oxidase/xanthine dehydrogenase [KO:K11177] [EC:1.17.1.4]
REQ_02740  putative xanthine dehydrogenase FAD-binding subunit [KO:K11178] [EC:1.17.1.4]
REQ_02750  putative xanthine dehydrogenase Fe-S binding subunit [KO:K13483]
REQ_34900  GMP synthase [KO:K01951] [EC:6.3.5.2]
REQ_21710  gmK; guanylate kinase GmK [KO:K00942] [EC:2.7.4.8]
REQ_25320  pykA; putative pyruvate kinase PykA [KO:K00873] [EC:2.7.1.40]
REQ_31950  nrdE; ribonucleoside-diphosphate reductase NrdE [KO:K00525] [EC:1.17.4.1]
REQ_31940  nrdF; ribonucleoside-diphosphate reductase NrdF [KO:K00526] [EC:1.17.4.1]
REQ_32860  nrdB; ribonucleoside-diphosphate reductase NrdB [KO:K00526] [EC:1.17.4.1]
REQ_01470  nrdF; ribonucleoside-diphosphate reductase beta subunit NrdF [KO:K00526] [EC:1.17.4.1]
REQ_29080  dGTPase [KO:K01129] [EC:3.1.5.1]
REQ_35570  rpoA; DNA-directed RNA polymerase alpha subunit RpoA [KO:K03040] [EC:2.7.7.6]
REQ_36700  rpoB; DNA-directed RNA polymerase beta subunit RpoB [KO:K03043] [EC:2.7.7.6]
REQ_36690  rpoC; DNA-directed RNA polymerase beta subunit RpoC [KO:K03046] [EC:2.7.7.6]
REQ_21720  rpoZ; DNA-directed RNA polymerase omega subunit RpoZ [KO:K03060] [EC:2.7.7.6]
REQ_25230  polA1; DNA polymerase I PolA1 [KO:K02335] [EC:2.7.7.7]
REQ_44470  polA2; putative DNA polymerase I PolA2 [KO:K02335] [EC:2.7.7.7]
REQ_27570  dnaE1; DNA polymerase III alpha subunit DnaE1 [KO:K02337] [EC:2.7.7.7]
REQ_00020  dnaN; DNA polymerase III beta subunit [KO:K02338] [EC:2.7.7.7]
REQ_03670  DNA polymerase III gamma subunit [KO:K02343] [EC:2.7.7.7]
REQ_29600  DNA polymerase III delta subunit [KO:K02340] [EC:2.7.7.7]
REQ_05470  DNA polymerase III delta' subunit [KO:K02341] [EC:2.7.7.7]
REQ_28190  DNA polymerase III epsilon subunit [KO:K02342] [EC:2.7.7.7]
REQ_29050  putative DNA polymerase III epsilon subunit [KO:K02342] [EC:2.7.7.7]
REQ_37770  exopolyphosphatase [KO:K01524] [EC:3.6.1.40 3.6.1.11]
REQ_12660  guanosine-5'-triphosphate,3'-diphosphate diphosphatase [KO:K01524] [EC:3.6.1.40 3.6.1.11]
REQ_20940  GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [KO:K00951] [EC:2.7.6.5]
REQ_38470  conserved hypothetical protein [KO:K07816] [EC:2.7.6.5]
REQ_43040  putative adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
REQ_17660  putative adenylate/guanylate cyclase and histidine kinase domains [KO:K01768] [EC:4.6.1.1]
REQ_41370  putative adenylate/guanylate cyclase and histidine kinase domains [KO:K01768] [EC:4.6.1.1]
REQ_39590  purA; adenylosuccinate synthetase PurA [KO:K01939] [EC:6.3.4.4]
REQ_28310  putative carbohydrate/pyrimidine kinase [KO:K00856] [EC:2.7.1.20]
REQ_14870  putative adenosine deaminase [KO:K01488] [EC:3.5.4.4]
REQ_34300  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
REQ_14340  putative lysine decarboxylase [KO:K06966] [EC:3.2.2.- 3.2.2.10]
REQ_14350  putative lysine decarboxylase [KO:K06966] [EC:3.2.2.- 3.2.2.10]
REQ_45710  putative lysine decarboxylase [KO:K06966] [EC:3.2.2.- 3.2.2.10]
REQ_35650  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
REQ_19300  pnp; polyribonucleotide nucleotidyltransferase Pnp [KO:K00962] [EC:2.7.7.8]
REQ_20760  conserved hypothetical protein [KO:K19710] [EC:2.7.7.53]
REQ_17330  cysNC; sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase CysNC [KO:K00955] [EC:2.7.1.25 2.7.7.4]
REQ_02250  cysNC; sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase CysNC [KO:K00955] [EC:2.7.1.25 2.7.7.4]
REQ_29400  cysN; sulfate adenylyltransferase subunit 1 CysN [KO:K00956] [EC:2.7.7.4]
REQ_17320  cysD; sulfate adenylyltransferase subunit 2 CysD [KO:K00957] [EC:2.7.7.4]
REQ_02240  cysD; sulfate adenylyltransferase subunit 2 CysD [KO:K00957] [EC:2.7.7.4]
REQ_29390  cysD; sulfate adenylyltransferase subunit 2 CysD [KO:K00957] [EC:2.7.7.4]
REQ_45390  ureC; urease alpha subunit UreC [KO:K01428] [EC:3.5.1.5]
REQ_45410  ureA; urease gamma subunit UreA [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
Reference
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
Reference
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
KO pathway
ko00230   

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