KEGG   PATHWAY: req00230
Entry
req00230                    Pathway                                
Name
Purine metabolism - Prescottella equi
Class
Metabolism; Nucleotide metabolism
Pathway map
req00230  Purine metabolism
req00230

Module
req_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:req00230]
req_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:req00230]
req_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:req00230]
req_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:req00230]
req_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:req00230]
req_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:req00230]
req_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:req00230]
Other DBs
GO: 0006163 0042278
Organism
Prescottella equi [GN:req]
Gene
REQ_01470  nrdF; ribonucleoside-diphosphate reductase beta subunit NrdF [KO:K00526] [EC:1.17.4.1]
REQ_02240  cysD; sulfate adenylyltransferase subunit 2 CysD [KO:K00957] [EC:2.7.7.4]
REQ_02250  cysNC; sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase CysNC [KO:K00955] [EC:2.7.7.4 2.7.1.25]
REQ_02610  [KO:K01081] [EC:3.1.3.5]
REQ_02730  [KO:K11177] [EC:1.17.1.4]
REQ_02740  [KO:K11178] [EC:1.17.1.4]
REQ_02750  [KO:K13483]
REQ_05690  [KO:K16840] [EC:4.1.1.97]
REQ_05810  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
REQ_07860  purD; phosphoribosylamine-glycine ligase PurD [KO:K01945] [EC:6.3.4.13]
REQ_07890  purB; adenylosuccinate lyase PurB [KO:K01756] [EC:4.3.2.2]
REQ_08080  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase PurC [KO:K01923] [EC:6.3.2.6]
REQ_08260  purS; phosphoribosylformylglycinamidine synthase PurS [KO:K23264]
REQ_08270  purQ; phosphoribosylformylglycinamidine synthase I PurQ [KO:K23265]
REQ_08350  purL; phosphoribosylformylglycinamidine synthase II PurL [KO:K23269]
REQ_08400  purF; amidophosphoribosyltransferase PurF [KO:K00764] [EC:2.4.2.14]
REQ_08410  purM; phosphoribosylformylglycinamidine cyclo-ligase PurM [KO:K01933] [EC:6.3.3.1]
REQ_11400  purN; secreted phosphoribosylglycinamide formyltransferase PurN [KO:K11175] [EC:2.1.2.2]
REQ_11410  purHJ; phosphoribosylphosphoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurHJ [KO:K00602] [EC:2.1.2.3 3.5.4.10]
REQ_12530  prsA; ribose-phosphate diphosphokinase PrsA [KO:K00948] [EC:2.7.6.1]
REQ_12570  [KO:K04765] [EC:3.6.1.9]
REQ_12660  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
REQ_14870  [KO:K21053] [EC:3.5.4.2]
REQ_17320  cysD; sulfate adenylyltransferase subunit 2 CysD [KO:K00957] [EC:2.7.7.4]
REQ_17330  cysNC; sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase CysNC [KO:K00955] [EC:2.7.7.4 2.7.1.25]
REQ_17910  [KO:K01519] [EC:3.6.1.66]
REQ_20760  [KO:K19710] [EC:2.7.7.53]
REQ_20930  [KO:K00759] [EC:2.4.2.7]
REQ_20940  [KO:K01139] [EC:2.7.6.5 3.1.7.2]
REQ_21710  gmK; guanylate kinase GmK [KO:K00942] [EC:2.7.4.8]
REQ_22710  [KO:K01239] [EC:3.2.2.1]
REQ_23010  [KO:K01487] [EC:3.5.4.3]
REQ_24270  guaB1; IMP dehydrogenase GuaB1 [KO:K26110]
REQ_27750  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
REQ_28310  [KO:K00856] [EC:2.7.1.20]
REQ_29080  [KO:K01129] [EC:3.1.5.1]
REQ_29390  cysD; sulfate adenylyltransferase subunit 2 CysD [KO:K00957] [EC:2.7.7.4]
REQ_29400  cysN; sulfate adenylyltransferase subunit 1 CysN [KO:K00956] [EC:2.7.7.4]
REQ_29870  ndkA; nucleoside-diphosphate kinase NdkA [KO:K00940] [EC:2.7.4.6]
REQ_31940  nrdF; ribonucleoside-diphosphate reductase NrdF [KO:K00526] [EC:1.17.4.1]
REQ_31950  nrdE; ribonucleoside-diphosphate reductase NrdE [KO:K00525] [EC:1.17.4.1]
REQ_32340  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
REQ_32860  nrdB; ribonucleoside-diphosphate reductase NrdB [KO:K00526] [EC:1.17.4.1]
REQ_33760  purE; phosphoribosylaminoimidazole carboxylase PurE [KO:K01588] [EC:5.4.99.18]
REQ_33770  purK; phosphoribosylaminoimidazole carboxylase PurK [KO:K01589] [EC:6.3.4.18]
REQ_34200  [KO:K03783] [EC:2.4.2.1]
REQ_34300  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
REQ_34900  [KO:K01951] [EC:6.3.5.2]
REQ_34920  [KO:K00088] [EC:1.1.1.205]
REQ_34930  guaB; IMP dehydrogenase GuaB [KO:K00088] [EC:1.1.1.205]
REQ_35650  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
REQ_37770  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
REQ_38470  [KO:K07816] [EC:2.7.6.5]
REQ_38960  [KO:K01768] [EC:4.6.1.1]
REQ_39260  nagA; N-acetylglucosamine-6-phosphate deacetylase NagA [KO:K02566] [EC:3.1.3.5]
REQ_39360  purT; phosphoribosylglycinamide formyltransferase PurT [KO:K08289] [EC:6.3.1.21]
REQ_39590  purA; adenylosuccinate synthetase PurA [KO:K01939] [EC:6.3.4.4]
REQ_41370  [KO:K01768] [EC:4.6.1.1]
REQ_43040  [KO:K01768] [EC:4.6.1.1]
REQ_45390  ureC; urease alpha subunit UreC [KO:K01428] [EC:3.5.1.5]
REQ_45410  ureA; urease gamma subunit UreA [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
req00030  Pentose phosphate pathway
req00220  Arginine biosynthesis
req00250  Alanine, aspartate and glutamate metabolism
req00260  Glycine, serine and threonine metabolism
req00340  Histidine metabolism
req00630  Glyoxylate and dicarboxylate metabolism
req00730  Thiamine metabolism
req00740  Riboflavin metabolism
req00790  Folate biosynthesis
KO pathway
ko00230   

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