KEGG   PATHWAY: rsi00290
Entry
rsi00290                    Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Runella slithyformis
Class
Metabolism; Amino acid metabolism
Pathway map
rsi00290  Valine, leucine and isoleucine biosynthesis
rsi00290

Module
rsi_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:rsi00290]
rsi_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:rsi00290]
rsi_M00535  Isoleucine biosynthesis, pyruvate => 2-oxobutanoate [PATH:rsi00290]
rsi_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:rsi00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Runella slithyformis [GN:rsi]
Gene
Runsl_0753  threonine dehydratase [KO:K01754] [EC:4.3.1.19]
Runsl_0744  (R)-citramalate synthase [KO:K09011] [EC:2.3.3.21]
Runsl_0746  3-isopropylmalate dehydratase, large subunit [KO:K01703] [EC:4.2.1.33 4.2.1.35]
Runsl_0745  3-isopropylmalate dehydratase, small subunit [KO:K01704] [EC:4.2.1.33 4.2.1.35]
Runsl_0742  3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
Runsl_0757  acetolactate synthase, large subunit, biosynthetic type [KO:K01652] [EC:2.2.1.6]
Runsl_0756  acetolactate synthase, small subunit [KO:K01653] [EC:2.2.1.6]
Runsl_0754  ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
Runsl_0758  Dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
Runsl_2120  D-amino-acid transaminase [KO:K00826] [EC:2.6.1.42]
Runsl_3138  branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
Runsl_4857  Aspartate transaminase [KO:K14260] [EC:2.6.1.66 2.6.1.2]
Runsl_0614  2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
PMID:15292141
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
rsi00260  Glycine, serine and threonine metabolism
rsi00280  Valine, leucine and isoleucine degradation
rsi00620  Pyruvate metabolism
KO pathway
ko00290   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG GENES (13)   
All databases (14)   

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