KEGG   PATHWAY: sgr00230
Entry
sgr00230                    Pathway                                
Name
Purine metabolism - Streptomyces griseus
Class
Metabolism; Nucleotide metabolism
Pathway map
sgr00230  Purine metabolism
sgr00230

Module
sgr_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sgr00230]
sgr_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sgr00230]
sgr_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sgr00230]
sgr_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sgr00230]
sgr_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sgr00230]
sgr_M00546  Purine degradation, xanthine => urea [PATH:sgr00230]
sgr_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:sgr00230]
Other DBs
GO: 0006163 0042278
Organism
Streptomyces griseus [GN:sgr]
Gene
SGR_6899  putative mutase [KO:K01839] [EC:5.4.2.7]
SGR_6728  putative phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
SGR_4383  putative ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
SGR_3877  putative phosphoribosylpyrophosphate amidotransferase [KO:K00764] [EC:2.4.2.14]
SGR_3859  putative phosphoribosylglycinamide synthetase [KO:K01945] [EC:6.3.4.13]
SGR_2718  putative phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
SGR_3871  putative phosphoribosyl formylglycinamidine synthase II [KO:K23269] [EC:6.3.5.3]
SGR_3869  putative phosphoribosylformylglycinamidine synthase PurS component [KO:K23264] [EC:6.3.5.3]
SGR_3870  putative phosphoribosylformylglycinamidine synthetase I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
SGR_3878  putative phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
SGR_4477  putative phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
SGR_4478  putative phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
SGR_3862  putative phosphoribosylaminoimidazole-succinocarboxamide synthetase [KO:K01923] [EC:6.3.2.6]
SGR_6272  putative adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
SGR_2717  putative bifunctional purine biosynthesis protein [KO:K00602] [EC:2.1.2.3 3.5.4.10]
SGR_6021  putative adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
SGR_6575  putative 5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
SGR_3941  putative 5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
SGR_4699  putative N-acetylglucosamine metabolism protein [KO:K02566] [EC:3.1.3.5]
SGR_2626  putative purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
SGR_5424  conserved hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
SGR_4087  putative hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
SGR_2756  putative inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
SGR_2757  putative inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
SGR_4930  putative nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
SGR_4640  conserved hypothetical protein [KO:K01519] [EC:3.6.1.66]
SGR_5078  putative dehydrogenase [KO:K13481] [EC:1.17.1.4]
SGR_5077  putative dehydrogenase [KO:K13482] [EC:1.17.1.4]
SGR_6760  putative oxidoreductase [KO:K11177] [EC:1.17.1.4]
SGR_6438  putative oxidoreductase [KO:K11177] [EC:1.17.1.4]
SGR_6759  putative oxidoreductase molybdopterin-binding subunit [KO:K11178] [EC:1.17.1.4]
SGR_6437  putative oxidoreductase molybdopterin-binding subunit [KO:K11178] [EC:1.17.1.4]
SGR_6436  putative xanthine dehydrogenase [KO:K13483]
SGR_6758  putative oxidoreductase iron-sulphur-binding subunit [KO:K13483]
SGR_2745  putative GMP synthase [KO:K01951] [EC:6.3.5.2]
SGR_6066  putative inosine-5'-monophosphate dehydrogenase [KO:K26110] [EC:1.7.1.7]
SGR_6055  putative guanylate kinase [KO:K00942] [EC:2.7.4.8]
SGR_1715  putative vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
SGR_2299  putative ribonucleoside-diphosphate reductase large subunit [KO:K00525] [EC:1.17.4.1]
SGR_2300  putative ribonucleoside-diphosphate reductase small subunit [KO:K00526] [EC:1.17.4.1]
SGR_5064  putative deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
SGR_1726  relA2; putative ppGpp synthetase/hydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
SGR_6022  relA1; putative ppGpp synthetase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
SGR_4132  putative exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
SGR_4442  putative exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
SGR_2614  cyaA; adenylate cyclase [KO:K01768] [EC:4.6.1.1]
SGR_3404  putative adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
SGR_5350  putative carbohydrate kinase [KO:K00856] [EC:2.7.1.20]
SGR_2641  putative adenosine deaminase [KO:K01488] [EC:3.5.4.4]
SGR_2878  putative adenosine deaminase [KO:K01488] [EC:3.5.4.4]
SGR_4999  putative adenosine deaminase [KO:K21053] [EC:3.5.4.2]
SGR_5514  putative 5'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
SGR_2813  putative adenylate kinase [KO:K00939] [EC:2.7.4.3]
SGR_5609  putative cyclic nucleotide phosphodiesterase [KO:K03651] [EC:3.1.4.53]
SGR_6005  conserved hypothetical protein [KO:K19710] [EC:2.7.7.53]
SGR_1394  putative adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
SGR_1396  putative sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
SGR_1395  putative sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
SGR_1309  putative uricase [KO:K00365] [EC:1.7.3.3]
SGR_1310  conserved hypothetical protein [KO:K07127] [EC:3.5.2.17]
SGR_1311  conserved hypothetical protein [KO:K16840] [EC:4.1.1.97]
SGR_2686  conserved hypothetical protein [KO:K16840] [EC:4.1.1.97]
SGR_1289  putative allantoinase [KO:K01466] [EC:3.5.2.5]
SGR_4882  putative allantoicase [KO:K01477] [EC:3.5.3.4]
SGR_1288  putative allantoicase [KO:K01477] [EC:3.5.3.4]
SGR_6297  ureC1; putative urease alpha subunit [KO:K01428] [EC:3.5.1.5]
SGR_846  ureC2; putative urease alpha subunit [KO:K01428] [EC:3.5.1.5]
SGR_236  ureC3; putative urease alpha subunit [KO:K01428] [EC:3.5.1.5]
SGR_237  ureB3; putative urease beta subunit [KO:K01429] [EC:3.5.1.5]
SGR_6296  ureB1; putative urease beta subunit [KO:K01429] [EC:3.5.1.5]
SGR_847  ureB2; putative urease beta subunit [KO:K01429] [EC:3.5.1.5]
SGR_6295  ureA1; putative urease gamma subunit [KO:K01430] [EC:3.5.1.5]
SGR_238  ureA3; putative urease gamma subunit [KO:K01430] [EC:3.5.1.5]
SGR_849  ureA2; putative urease gamma subunit [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sgr00030  Pentose phosphate pathway
sgr00220  Arginine biosynthesis
sgr00250  Alanine, aspartate and glutamate metabolism
sgr00260  Glycine, serine and threonine metabolism
sgr00340  Histidine metabolism
sgr00630  Glyoxylate and dicarboxylate metabolism
sgr00730  Thiamine metabolism
sgr00740  Riboflavin metabolism
sgr00790  Folate biosynthesis
KO pathway
ko00230   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (74)   
   KEGG GENES (74)   
All databases (75)   

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