KEGG   PATHWAY: spx00230
Entry
spx00230                    Pathway                                
Name
Purine metabolism - Streptococcus pneumoniae G54 (serotype 19F)
Class
Metabolism; Nucleotide metabolism
Pathway map
spx00230  Purine metabolism
spx00230

Module
spx_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:spx00230]
spx_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:spx00230]
spx_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:spx00230]
spx_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:spx00230]
spx_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:spx00230]
Other DBs
GO: 0006163 0042278
Organism
Streptococcus pneumoniae G54 (serotype 19F) [GN:spx]
Gene
SPG_0914  hydrolase, NUDIX family [KO:K01515] [EC:3.6.1.13 3.6.1.-]
SPG_0750  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
SPG_1421  Phosphoglucomutase/phosphomannomutase family protein [KO:K01835] [EC:5.4.2.2]
SPG_0034  prs1; ribose-phosphate pyrophosphokinase 1 [KO:K00948] [EC:2.7.6.1]
SPG_1015  prs2; ribose-phosphate pyrophosphokinase 2 [KO:K00948] [EC:2.7.6.1]
SPG_0052  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
SPG_0057  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
SPG_0054  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
SPG_0051  purL; phosphoribosylformylglycinamide synthetase [KO:K01952] [EC:6.3.5.3]
SPG_0053  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
SPG_0059  purK; phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
SPG_0058  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
SPG_0050  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
SPG_0061  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
SPG_0056  purH; bifunctional purine biosynthesis protein [KO:K00602] [EC:2.1.2.3 3.5.4.10]
SPG_1503  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
SPG_0752  pnp; purine nucleoside phosphorylase I, inosine and guanosine-specific [KO:K03783] [EC:2.4.2.1]
SPG_0756  deoD; Purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
SPG_0012  hpt; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
SPG_2174  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
SPG_1860  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
SPG_1765  Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family protein [KO:K01519] [EC:3.6.1.66]
SPG_1731  xpt; xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
SPG_1373  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
SPG_1140  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
SPG_1644  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
SPG_1077  nrdA; ribonucleoside-diphosphate reductase, alpha subunitv [KO:K00525] [EC:1.17.4.1]
SPG_1078  nrdB; ribonucleoside-diphosphate reductase beta subunit [KO:K00526] [EC:1.17.4.1]
SPG_0189  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
SPG_1555  GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
SPG_1017  pyrophosphokinase family protein [KO:K07816] [EC:2.7.6.5]
SPG_0025  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
SPG_0216  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
SPG_2090  carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
spx00030  Pentose phosphate pathway
spx00220  Arginine biosynthesis
spx00250  Alanine, aspartate and glutamate metabolism
spx00260  Glycine, serine and threonine metabolism
spx00630  Glyoxylate and dicarboxylate metabolism
spx00730  Thiamine metabolism
spx00740  Riboflavin metabolism
spx00790  Folate biosynthesis
KO pathway
ko00230   

  All links  
Genome (1)   
   KEGG GENOME (1)   
Gene (34)   
   KEGG GENES (34)   
All databases (35)   

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