KEGG   PATHWAY: zma00920Help
zma00920                    Pathway                                

Sulfur metabolism - Zea mays (maize)
Sulfur is an essential element for life and the metabolism of organic sulfur compounds plays an important role in the global sulfur cycle. Sulfur occurs in various oxidation states ranging from +6 in sulfate to -2 in sulfide (H2S). Sulfate reduction can occur in both an energy consuming assimilatory pathway and an energy producing dissimilatory pathway. The assimilatory pathway, which is found in a wide range of organisms, produces reduced sulfur compounds for the biosynthesis of S-containing amino acids and does not lead to direct excretion of sulfide. In the dissimilatory pathway, which is restricted to obligatory anaerobic bacterial and archaeal lineages, sulfate (or sulfur) is the terminal electron acceptor of the respiratory chain producing large quantities of inorganic sulfide. Both pathways start from the activation of sulfate by reaction with ATP to form adenylyl sulfate (APS). In the assimilatory pathway [MD:M00176] APS is converted to 3'-phosphoadenylyl sulfate (PAPS) and then reduced to sulfite, and sulfite is further reduced to sulfide by the assimilatory sulfite reductase. In the dissimilatory pathway [MD:M00596] APS is directly reduced to sulfite, and sulfite is further reduced to sulfide by the dissimilatory sulfite reductase. The capacity for oxidation of sulfur is quite widespread among bacteria and archaea, comprising phototrophs and chemolithoautotrophs. The SOX (sulfur-oxidation) system [MD:M00595] is a well-known sulfur oxidation pathway and is found in both photosynthetic and non-photosynthetic sulfur-oxidizing bacteria. Green sulfur bacteria and purple sulfur bacteria carry out anoxygenic photosynthesis with reduced sulfur compounds such as sulfide and elemental sulfur, as well as thiosulfate (in some species with the SOX system), as the electron donor for photoautotrophic growth. In some chemolithoautotrophic sulfur oxidizers (such as Thiobacillus denitrificans), it has been suggested that dissimilatory sulfur reduction enzymes operate in the reverse direction, forming a sulfur oxidation pathway from sulfite to APS and then to sulfate.
Metabolism; Energy metabolism
BRITE hierarchy
Pathway map
zma00920  Sulfur metabolism

Ortholog table
Other DBs
BSID: 125639
GO: 0006790
Zea mays (maize) [GN:zma]
103645431  ATP sulfurylase 1, chloroplastic-like [KO:K13811] [EC:]
100281036  bifunctional 3-phosphoadenosine 5-phosphosulfate synthetase 2 [KO:K13811] [EC:]
103643994  ATP-sulfurylase 3, chloroplastic-like [KO:K13811] [EC:]
103641688  ATP sulfurylase 1, chloroplastic-like [KO:K13811] [EC:]
103625889  ATP-sulfurylase 3, chloroplastic-like [KO:K13811] [EC:]
103640445  ATP sulfurylase 1, chloroplastic-like [KO:K13811] [EC:]
103637465  ATP sulfurylase 1, chloroplastic-like [KO:K13811] [EC:]
100217102  adenylyl-sulfate kinase [KO:K00860] [EC:]
100276991  adenylyl-sulfate kinase [KO:K00860] [EC:]
100193315  cl1019_1; uncharacterized protein LOC100193315 isoform 2 [KO:K00860] [EC:]
100285812  PAP-specific phosphatase [KO:K01082] [EC:]
100192833  si946019d11; uncharacterized protein LOC100192833 [KO:K01082] [EC:]
100276170  cl14808_1; uncharacterized protein LOC100276170 [KO:K15422] [EC:]
542492  dnp1; diphosphonucleotide phosphatase 1 [KO:K15422] [EC:]
103647705  aprl2; adenosine 5'-phosphosulfate reductase-like 2 [KO:K05907] [EC:]
606419  aprl1; adenosine 5'-phosphosulfate reductase-like 1 [KO:K05907] [EC:]
103642918  sulfite oxidase isoform X1 [KO:K00387] [EC:]
100284296  pco137761b; uncharacterized protein LOC100284296 [KO:K00387] [EC:]
542221  cl122_1; sulfite reductase [ferredoxin], chloroplastic [KO:K00392] [EC:]
100283164  IDP546; uncharacterized protein LOC100283164 [KO:K17725] [EC:]
100275494  pco128327; uncharacterized protein LOC100275494 [KO:K01011] [EC:]
100272428  uncharacterized LOC100272428 [KO:K01011] [EC:]
103631673  probable serine acetyltransferase 2 [KO:K00640] [EC:]
542499  sat3; serine acetyltransferase 3 [KO:K00640] [EC:]
541958  sat1; serine acetyltransferase 1 [KO:K00640] [EC:]
541959  sat2; serine acetyltransferase 2 [KO:K00640] [EC:]
100280321  cys1; cysteine synthase 1 [KO:K01738] [EC:]
100193476  uncharacterized protein LOC100193476 [KO:K01738] [EC:]
103646469  cysteine synthase [KO:K01738] [EC:]
100272829  uncharacterized protein LOC100272829 [KO:K01738] [EC:]
100502310  cysteine synthase [KO:K01738] [EC:]
542438  cys2; cysteine synthase [KO:K01738] [EC:]
103651084  uncharacterized protein LOC103651084 [KO:K01738] [EC:]
100216991  pco146545; uncharacterized protein LOC100216991 [KO:K01738] [EC:]
103638079  cysteine synthase [KO:K01738] [EC:]
103638081  putative inactive cysteine synthase 2 [KO:K01738] [EC:]
109942192  putative inactive cysteine synthase 2 [KO:K01738] [EC:]
109939155  putative inactive cysteine synthase 2 isoform X2 [KO:K01738] [EC:]
100216722  cysteine synthase [KO:K13034] [EC:]
103645417  probable cystathionine gamma-synthase 2 [KO:K01739] [EC:]
103645418  probable cystathionine gamma-synthase 2 [KO:K01739] [EC:]
100191523  uncharacterized protein LOC100191523 [KO:K01739] [EC:]
541650  cgs1; cystathionine gamma-synthase 1 [KO:K01739] [EC:]
C00033  Acetate
C00042  Succinate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00065  L-Serine
C00084  Acetaldehyde
C00087  Sulfur
C00094  Sulfite
C00097  L-Cysteine
C00155  L-Homocysteine
C00224  Adenylyl sulfate
C00245  Taurine
C00263  L-Homoserine
C00283  Hydrogen sulfide
C00320  Thiosulfate
C00409  Methanethiol
C00580  Dimethyl sulfide
C00979  O-Acetyl-L-serine
C01118  O-Succinyl-L-homoserine
C01861  Trithionate
C02084  Tetrathionate
C03920  2-(Methylthio)ethanesulfonate
C04022  S,S-Dimethyl-beta-propiothetin
C08276  3-(Methylthio)propanoate
C11142  Dimethyl sulfone
C11143  Dimethyl sulfoxide
C11145  Methanesulfonic acid
C15521  Alkanesulfonate
C17267  S-Sulfanylglutathione
C19692  Polysulfide
C20870  3-(Methylthio)propanoyl-CoA
C20955  3-(Methylthio)acryloyl-CoA
Grein F, Ramos AR, Venceslau SS, Pereira IA
Unifying concepts in anaerobic respiration: Insights from dissimilatory sulfur metabolism.
Biochim Biophys Acta 1827:145-60 (2013)
Fauque GD, Barton LL
Hemoproteins in dissimilatory sulfate- and sulfur-reducing prokaryotes.
Adv Microb Physiol 60:1-90 (2012)
Sakurai H, Ogawa T, Shiga M, Inoue K
Inorganic sulfur oxidizing system in green sulfur bacteria.
Photosynth Res 104:163-76 (2010)
Falkenby LG, Szymanska M, Holkenbrink C, Habicht KS, Andersen JS, Miller M, Frigaard NU
Quantitative proteomics of Chlorobaculum tepidum: insights into the sulfur metabolism of a phototrophic green sulfur bacterium.
FEMS Microbiol Lett 323:142-50 (2011)
Gregersen LH, Bryant DA, Frigaard NU
Mechanisms and evolution of oxidative sulfur metabolism in green sulfur bacteria.
Front Microbiol 2:116 (2011)
Beller HR, Chain PS, Letain TE, Chakicherla A, Larimer FW, Richardson PM, Coleman MA, Wood AP, Kelly DP.
The genome sequence of the obligately chemolithoautotrophic, facultatively anaerobic bacterium Thiobacillus denitrificans.
J Bacteriol 188:1473-88 (2006)
Pott AS, Dahl C
Sirohaem sulfite reductase and other proteins encoded by genes at the dsr locus of Chromatium vinosum are involved in the oxidation of intracellular sulfur.
Microbiology 144 ( Pt 7):1881-94 (1998)
Frigaard NU, Dahl C
Sulfur metabolism in phototrophic sulfur bacteria.
Adv Microb Physiol 54:103-200 (2009)
KO pathway

DBGET integrated database retrieval system