HEADER HYDROLASE 17-APR-19 6RGQ
TITLE HUMAN 20S PROTEASOME
COMPND MOL_ID: 1;
COMPND 2 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-6;
COMPND 3 CHAIN: A, O;
COMPND 4 SYNONYM: 27 KDA PROSOMAL PROTEIN,P27K,MACROPAIN IOTA CHAIN,
COMPND 5 MULTICATALYTIC ENDOPEPTIDASE COMPLEX IOTA CHAIN,PROTEASOME IOTA
COMPND 6 CHAIN;
COMPND 7 EC: 3.4.25.1;
COMPND 8 ENGINEERED: YES;
COMPND 9 MOL_ID: 2;
COMPND 10 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-2;
COMPND 11 CHAIN: B, P;
COMPND 12 SYNONYM: MACROPAIN SUBUNIT C3,MULTICATALYTIC ENDOPEPTIDASE COMPLEX
COMPND 13 SUBUNIT C3,PROTEASOME COMPONENT C3;
COMPND 14 EC: 3.4.25.1;
COMPND 15 ENGINEERED: YES;
COMPND 16 MOL_ID: 3;
COMPND 17 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-4;
COMPND 18 CHAIN: C, Q;
COMPND 19 SYNONYM: MACROPAIN SUBUNIT C9,MULTICATALYTIC ENDOPEPTIDASE COMPLEX
COMPND 20 SUBUNIT C9,PROTEASOME COMPONENT C9,PROTEASOME SUBUNIT L;
COMPND 21 EC: 3.4.25.1;
COMPND 22 ENGINEERED: YES;
COMPND 23 MOL_ID: 4;
COMPND 24 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-7;
COMPND 25 CHAIN: D, R;
COMPND 26 SYNONYM: PROTEASOME SUBUNIT RC6-1,PROTEASOME SUBUNIT XAPC7;
COMPND 27 EC: 3.4.25.1;
COMPND 28 ENGINEERED: YES;
COMPND 29 MOL_ID: 5;
COMPND 30 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-5;
COMPND 31 CHAIN: E, S;
COMPND 32 SYNONYM: MACROPAIN ZETA CHAIN,MULTICATALYTIC ENDOPEPTIDASE COMPLEX
COMPND 33 ZETA CHAIN,PROTEASOME ZETA CHAIN;
COMPND 34 EC: 3.4.25.1;
COMPND 35 ENGINEERED: YES;
COMPND 36 MOL_ID: 6;
COMPND 37 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-1;
COMPND 38 CHAIN: F, T;
COMPND 39 SYNONYM: 30 KDA PROSOMAL PROTEIN,PROS-30,MACROPAIN SUBUNIT C2,
COMPND 40 MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT C2,PROTEASOME COMPONENT
COMPND 41 C2,PROTEASOME NU CHAIN;
COMPND 42 EC: 3.4.25.1;
COMPND 43 ENGINEERED: YES;
COMPND 44 MOL_ID: 7;
COMPND 45 MOLECULE: PROTEASOME SUBUNIT ALPHA TYPE-3;
COMPND 46 CHAIN: G, U;
COMPND 47 SYNONYM: MACROPAIN SUBUNIT C8,MULTICATALYTIC ENDOPEPTIDASE COMPLEX
COMPND 48 SUBUNIT C8,PROTEASOME COMPONENT C8;
COMPND 49 EC: 3.4.25.1;
COMPND 50 ENGINEERED: YES;
COMPND 51 MOL_ID: 8;
COMPND 52 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-6;
COMPND 53 CHAIN: H, V;
COMPND 54 SYNONYM: MACROPAIN DELTA CHAIN,MULTICATALYTIC ENDOPEPTIDASE COMPLEX
COMPND 55 DELTA CHAIN,PROTEASOME DELTA CHAIN,PROTEASOME SUBUNIT Y;
COMPND 56 EC: 3.4.25.1;
COMPND 57 ENGINEERED: YES;
COMPND 58 MOL_ID: 9;
COMPND 59 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-7;
COMPND 60 CHAIN: I, W;
COMPND 61 SYNONYM: MACROPAIN CHAIN Z,MULTICATALYTIC ENDOPEPTIDASE COMPLEX CHAIN
COMPND 62 Z,PROTEASOME SUBUNIT Z;
COMPND 63 EC: 3.4.25.1;
COMPND 64 ENGINEERED: YES;
COMPND 65 MOL_ID: 10;
COMPND 66 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-3;
COMPND 67 CHAIN: J, X;
COMPND 68 SYNONYM: PROTEASOME CHAIN 13,PROTEASOME COMPONENT C10-II,PROTEASOME
COMPND 69 THETA CHAIN;
COMPND 70 EC: 3.4.25.1;
COMPND 71 ENGINEERED: YES;
COMPND 72 MOL_ID: 11;
COMPND 73 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-2;
COMPND 74 CHAIN: K, Y;
COMPND 75 SYNONYM: MACROPAIN SUBUNIT C7-I,MULTICATALYTIC ENDOPEPTIDASE COMPLEX
COMPND 76 SUBUNIT C7-I,PROTEASOME COMPONENT C7-I;
COMPND 77 EC: 3.4.25.1;
COMPND 78 ENGINEERED: YES;
COMPND 79 MOL_ID: 12;
COMPND 80 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-5;
COMPND 81 CHAIN: L, Z;
COMPND 82 SYNONYM: MACROPAIN EPSILON CHAIN,MULTICATALYTIC ENDOPEPTIDASE COMPLEX
COMPND 83 EPSILON CHAIN,PROTEASOME CHAIN 6,PROTEASOME EPSILON CHAIN,PROTEASOME
COMPND 84 SUBUNIT MB1,PROTEASOME SUBUNIT X;
COMPND 85 EC: 3.4.25.1;
COMPND 86 ENGINEERED: YES;
COMPND 87 MOL_ID: 13;
COMPND 88 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-1;
COMPND 89 CHAIN: M, a;
COMPND 90 SYNONYM: MACROPAIN SUBUNIT C5,MULTICATALYTIC ENDOPEPTIDASE COMPLEX
COMPND 91 SUBUNIT C5,PROTEASOME COMPONENT C5,PROTEASOME GAMMA CHAIN;
COMPND 92 EC: 3.4.25.1;
COMPND 93 ENGINEERED: YES;
COMPND 94 MOL_ID: 14;
COMPND 95 MOLECULE: PROTEASOME SUBUNIT BETA TYPE-4;
COMPND 96 CHAIN: N, b;
COMPND 97 SYNONYM: 26 KDA PROSOMAL PROTEIN,PROS-26,MACROPAIN BETA CHAIN,
COMPND 98 MULTICATALYTIC ENDOPEPTIDASE COMPLEX BETA CHAIN,PROTEASOME BETA
COMPND 99 CHAIN,PROTEASOME CHAIN 3,HSN3;
COMPND 100 EC: 3.4.25.1;
COMPND 101 ENGINEERED: YES
SOURCE MOL_ID: 1;
SOURCE 2 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 3 ORGANISM_COMMON: HUMAN;
SOURCE 4 ORGANISM_TAXID: 9606;
SOURCE 5 GENE: PSMA6, PROS27;
SOURCE 6 EXPRESSION_SYSTEM: SPODOPTERA FRUGIPERDA;
SOURCE 7 EXPRESSION_SYSTEM_TAXID: 7108;
SOURCE 8 MOL_ID: 2;
SOURCE 9 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 10 ORGANISM_COMMON: HUMAN;
SOURCE 11 ORGANISM_TAXID: 9606;
SOURCE 12 GENE: PSMA2, HC3, PSC3;
SOURCE 13 EXPRESSION_SYSTEM: SPODOPTERA FRUGIPERDA;
SOURCE 14 EXPRESSION_SYSTEM_TAXID: 7108;
SOURCE 15 MOL_ID: 3;
SOURCE 16 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 17 ORGANISM_COMMON: HUMAN;
SOURCE 18 ORGANISM_TAXID: 9606;
SOURCE 19 GENE: PSMA4, HC9, PSC9;
SOURCE 20 EXPRESSION_SYSTEM: SPODOPTERA FRUGIPERDA;
SOURCE 21 EXPRESSION_SYSTEM_TAXID: 7108;
SOURCE 22 MOL_ID: 4;
SOURCE 23 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 24 ORGANISM_COMMON: HUMAN;
SOURCE 25 ORGANISM_TAXID: 9606;
SOURCE 26 GENE: PSMA7, HSPC;
SOURCE 27 EXPRESSION_SYSTEM: SPODOPTERA FRUGIPERDA;
SOURCE 28 EXPRESSION_SYSTEM_TAXID: 7108;
SOURCE 29 MOL_ID: 5;
SOURCE 30 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 31 ORGANISM_COMMON: HUMAN;
SOURCE 32 ORGANISM_TAXID: 9606;
SOURCE 33 GENE: PSMA5;
SOURCE 34 EXPRESSION_SYSTEM: SPODOPTERA FRUGIPERDA;
SOURCE 35 EXPRESSION_SYSTEM_TAXID: 7108;
SOURCE 36 MOL_ID: 6;
SOURCE 37 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 38 ORGANISM_COMMON: HUMAN;
SOURCE 39 ORGANISM_TAXID: 9606;
SOURCE 40 GENE: PSMA1, HC2, NU, PROS30, PSC2;
SOURCE 41 EXPRESSION_SYSTEM: SPODOPTERA FRUGIPERDA;
SOURCE 42 EXPRESSION_SYSTEM_TAXID: 7108;
SOURCE 43 MOL_ID: 7;
SOURCE 44 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 45 ORGANISM_COMMON: HUMAN;
SOURCE 46 ORGANISM_TAXID: 9606;
SOURCE 47 GENE: PSMA3, HC8, PSC8;
SOURCE 48 EXPRESSION_SYSTEM: SPODOPTERA FRUGIPERDA;
SOURCE 49 EXPRESSION_SYSTEM_TAXID: 7108;
SOURCE 50 MOL_ID: 8;
SOURCE 51 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 52 ORGANISM_COMMON: HUMAN;
SOURCE 53 ORGANISM_TAXID: 9606;
SOURCE 54 GENE: PSMB6, LMPY, Y;
SOURCE 55 EXPRESSION_SYSTEM: SPODOPTERA FRUGIPERDA;
SOURCE 56 EXPRESSION_SYSTEM_TAXID: 7108;
SOURCE 57 MOL_ID: 9;
SOURCE 58 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 59 ORGANISM_COMMON: HUMAN;
SOURCE 60 ORGANISM_TAXID: 9606;
SOURCE 61 GENE: PSMB7, Z;
SOURCE 62 EXPRESSION_SYSTEM: SPODOPTERA FRUGIPERDA;
SOURCE 63 EXPRESSION_SYSTEM_TAXID: 7108;
SOURCE 64 MOL_ID: 10;
SOURCE 65 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 66 ORGANISM_COMMON: HUMAN;
SOURCE 67 ORGANISM_TAXID: 9606;
SOURCE 68 GENE: PSMB3;
SOURCE 69 EXPRESSION_SYSTEM: SPODOPTERA FRUGIPERDA;
SOURCE 70 EXPRESSION_SYSTEM_TAXID: 7108;
SOURCE 71 MOL_ID: 11;
SOURCE 72 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 73 ORGANISM_COMMON: HUMAN;
SOURCE 74 ORGANISM_TAXID: 9606;
SOURCE 75 GENE: PSMB2;
SOURCE 76 EXPRESSION_SYSTEM: SPODOPTERA FRUGIPERDA;
SOURCE 77 EXPRESSION_SYSTEM_TAXID: 7108;
SOURCE 78 MOL_ID: 12;
SOURCE 79 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 80 ORGANISM_COMMON: HUMAN;
SOURCE 81 ORGANISM_TAXID: 9606;
SOURCE 82 GENE: PSMB5, LMPX, MB1, X;
SOURCE 83 EXPRESSION_SYSTEM: SPODOPTERA FRUGIPERDA;
SOURCE 84 EXPRESSION_SYSTEM_TAXID: 7108;
SOURCE 85 MOL_ID: 13;
SOURCE 86 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 87 ORGANISM_COMMON: HUMAN;
SOURCE 88 ORGANISM_TAXID: 9606;
SOURCE 89 GENE: PSMB1, PSC5;
SOURCE 90 EXPRESSION_SYSTEM: SPODOPTERA FRUGIPERDA;
SOURCE 91 EXPRESSION_SYSTEM_TAXID: 7108;
SOURCE 92 MOL_ID: 14;
SOURCE 93 ORGANISM_SCIENTIFIC: HOMO SAPIENS;
SOURCE 94 ORGANISM_COMMON: HUMAN;
SOURCE 95 ORGANISM_TAXID: 9606;
SOURCE 96 GENE: PSMB4, PROS26;
SOURCE 97 EXPRESSION_SYSTEM: SPODOPTERA FRUGIPERDA;
SOURCE 98 EXPRESSION_SYSTEM_TAXID: 7108
KEYWDS PROTEASOME, HYDROLASE
EXPDTA ELECTRON MICROSCOPY
AUTHOR A.TOSTE REGO,P.C.A.DA FONSECA
REVDAT 3 16-OCT-19 6RGQ 1 JRNL
REVDAT 2 11-SEP-19 6RGQ 1 JRNL
REVDAT 1 04-SEP-19 6RGQ 0
JRNL AUTH A.TOSTE REGO,P.C.A.DA FONSECA
JRNL TITL CHARACTERIZATION OF FULLY RECOMBINANT HUMAN 20S AND
JRNL TITL 2 20S-PA200 PROTEASOME COMPLEXES.
JRNL REF MOL.CELL V. 76 138 2019
JRNL REFN ISSN 1097-2765
JRNL PMID 31473102
JRNL DOI 10.1016/J.MOLCEL.2019.07.014
REMARK 2
REMARK 2 RESOLUTION. 2.60 ANGSTROMS.
REMARK 3
REMARK 3 REFINEMENT.
REMARK 3 SOFTWARE PACKAGES : EPU, CISTEM, COOT, CISTEM, CISTEM,
REMARK 3 CISTEM, PHENIX, COOT
REMARK 3 RECONSTRUCTION SCHEMA : NULL
REMARK 3
REMARK 3 EM MAP-MODEL FITTING AND REFINEMENT
REMARK 3 PDB ENTRY : 5LE5
REMARK 3 REFINEMENT SPACE : REAL
REMARK 3 REFINEMENT PROTOCOL : RIGID BODY FIT
REMARK 3 REFINEMENT TARGET : NULL
REMARK 3 OVERALL ANISOTROPIC B VALUE : NULL
REMARK 3
REMARK 3 FITTING PROCEDURE : NULL
REMARK 3
REMARK 3 EM IMAGE RECONSTRUCTION STATISTICS
REMARK 3 NOMINAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 ACTUAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 EFFECTIVE RESOLUTION (ANGSTROMS) : 2.600
REMARK 3 NUMBER OF PARTICLES : 50885
REMARK 3 CTF CORRECTION METHOD : PHASE FLIPPING AND AMPLITUDE
REMARK 3 CORRECTION
REMARK 3
REMARK 3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL
REMARK 3
REMARK 3 OTHER DETAILS: NULL
REMARK 4
REMARK 4 6RGQ COMPLIES WITH FORMAT V. 3.30, 13-JUL-11
REMARK 100
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBE ON 17-APR-19.
REMARK 100 THE DEPOSITION ID IS D_1292101780.
REMARK 245
REMARK 245 EXPERIMENTAL DETAILS
REMARK 245 RECONSTRUCTION METHOD : SINGLE PARTICLE
REMARK 245 SPECIMEN TYPE : NULL
REMARK 245
REMARK 245 ELECTRON MICROSCOPE SAMPLE
REMARK 245 SAMPLE TYPE : PARTICLE
REMARK 245 PARTICLE TYPE : POINT
REMARK 245 NAME OF SAMPLE : HUMAN 20S PROTEASOME
REMARK 245 SAMPLE CONCENTRATION (MG ML-1) : 0.10
REMARK 245 SAMPLE SUPPORT DETAILS : NULL
REMARK 245 SAMPLE VITRIFICATION DETAILS : NULL
REMARK 245 SAMPLE BUFFER : NULL
REMARK 245 PH : 7.40
REMARK 245 SAMPLE DETAILS : NULL
REMARK 245
REMARK 245 DATA ACQUISITION
REMARK 245 DATE OF EXPERIMENT : NULL
REMARK 245 NUMBER OF MICROGRAPHS-IMAGES : 483
REMARK 245 TEMPERATURE (KELVIN) : NULL
REMARK 245 MICROSCOPE MODEL : FEI TITAN KRIOS
REMARK 245 DETECTOR TYPE : FEI FALCON III (4K X 4K)
REMARK 245 MINIMUM DEFOCUS (NM) : NULL
REMARK 245 MAXIMUM DEFOCUS (NM) : NULL
REMARK 245 MINIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 MAXIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 NOMINAL CS : NULL
REMARK 245 IMAGING MODE : BRIGHT FIELD
REMARK 245 ELECTRON DOSE (ELECTRONS NM**-2) : 45.70
REMARK 245 ILLUMINATION MODE : FLOOD BEAM
REMARK 245 NOMINAL MAGNIFICATION : 95000
REMARK 245 CALIBRATED MAGNIFICATION : NULL
REMARK 245 SOURCE : FIELD EMISSION GUN
REMARK 245 ACCELERATION VOLTAGE (KV) : 300
REMARK 245 IMAGING DETAILS : NULL
REMARK 247
REMARK 247 ELECTRON MICROSCOPY
REMARK 247 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON
REMARK 247 MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE
REMARK 247 THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES
REMARK 247 ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION
REMARK 247 OF THE STRUCTURE FACTORS.
REMARK 300
REMARK 300 BIOMOLECULE: 1
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON
REMARK 300 BURIED SURFACE AREA.
REMARK 350
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS
REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.
REMARK 350
REMARK 350 BIOMOLECULE: 1
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: 28-MERIC
REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: 28-MERIC
REMARK 350 SOFTWARE USED: PISA
REMARK 350 TOTAL BURIED SURFACE AREA: 103280 ANGSTROM**2
REMARK 350 SURFACE AREA OF THE COMPLEX: 203420 ANGSTROM**2
REMARK 350 CHANGE IN SOLVENT FREE ENERGY: -417.0 KCAL/MOL
REMARK 350 APPLY THE FOLLOWING TO CHAINS: A, B, C, D, E, F, G, H, I, J,
REMARK 350 AND CHAINS: K, L, M, N, O, P, Q, R, S,
REMARK 350 AND CHAINS: T, U, V, W, X, Y, Z, a, b
REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000
REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000
REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000
REMARK 465
REMARK 465 MISSING RESIDUES
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)
REMARK 465
REMARK 465 M RES C SSSEQI
REMARK 465 MET A 1
REMARK 465 SER A 2
REMARK 465 ALA A 243
REMARK 465 GLU A 244
REMARK 465 ARG A 245
REMARK 465 ASP A 246
REMARK 465 MET B 0
REMARK 465 ALA B 1
REMARK 465 GLU B 2
REMARK 465 ILE B 232
REMARK 465 ALA B 233
REMARK 465 MET C 1
REMARK 465 ARG C 249
REMARK 465 GLU C 250
REMARK 465 LYS C 251
REMARK 465 LYS C 252
REMARK 465 GLU C 253
REMARK 465 LYS C 254
REMARK 465 GLU C 255
REMARK 465 GLN C 256
REMARK 465 LYS C 257
REMARK 465 GLU C 258
REMARK 465 LYS C 259
REMARK 465 ASP C 260
REMARK 465 LYS C 261
REMARK 465 MET D 1
REMARK 465 LYS D 234
REMARK 465 GLU D 235
REMARK 465 LYS D 236
REMARK 465 GLU D 237
REMARK 465 GLU D 238
REMARK 465 ASN D 239
REMARK 465 GLU D 240
REMARK 465 LYS D 241
REMARK 465 LYS D 242
REMARK 465 LYS D 243
REMARK 465 GLN D 244
REMARK 465 LYS D 245
REMARK 465 LYS D 246
REMARK 465 ALA D 247
REMARK 465 SER D 248
REMARK 465 MET E 1
REMARK 465 PHE E 2
REMARK 465 LEU E 3
REMARK 465 THR E 4
REMARK 465 ARG E 5
REMARK 465 SER E 6
REMARK 465 GLU E 7
REMARK 465 TYR E 8
REMARK 465 MET F 1
REMARK 465 PHE F 2
REMARK 465 ARG F 3
REMARK 465 GLU F 237
REMARK 465 GLU F 238
REMARK 465 ARG F 239
REMARK 465 PRO F 240
REMARK 465 GLN F 241
REMARK 465 ARG F 242
REMARK 465 LYS F 243
REMARK 465 ALA F 244
REMARK 465 GLN F 245
REMARK 465 PRO F 246
REMARK 465 ALA F 247
REMARK 465 GLN F 248
REMARK 465 PRO F 249
REMARK 465 ALA F 250
REMARK 465 ASP F 251
REMARK 465 GLU F 252
REMARK 465 PRO F 253
REMARK 465 ALA F 254
REMARK 465 GLU F 255
REMARK 465 LYS F 256
REMARK 465 ALA F 257
REMARK 465 ASP F 258
REMARK 465 GLU F 259
REMARK 465 PRO F 260
REMARK 465 MET F 261
REMARK 465 GLU F 262
REMARK 465 HIS F 263
REMARK 465 MET G 0
REMARK 465 SER G 1
REMARK 465 SER G 2
REMARK 465 ILE G 3
REMARK 465 GLY G 4
REMARK 465 THR G 5
REMARK 465 GLU G 245
REMARK 465 GLU G 246
REMARK 465 ASP G 247
REMARK 465 GLU G 248
REMARK 465 SER G 249
REMARK 465 ASP G 250
REMARK 465 ASP G 251
REMARK 465 ASP G 252
REMARK 465 ASN G 253
REMARK 465 MET G 254
REMARK 465 PRO H 203
REMARK 465 PRO H 204
REMARK 465 ALA H 205
REMARK 465 ILE I 221
REMARK 465 GLU I 222
REMARK 465 VAL I 223
REMARK 465 LEU I 224
REMARK 465 GLU I 225
REMARK 465 GLU I 226
REMARK 465 THR I 227
REMARK 465 VAL I 228
REMARK 465 GLN I 229
REMARK 465 THR I 230
REMARK 465 MET I 231
REMARK 465 ASP I 232
REMARK 465 THR I 233
REMARK 465 SER I 234
REMARK 465 MET J 0
REMARK 465 PRO K 197
REMARK 465 LYS K 198
REMARK 465 GLN K 199
REMARK 465 GLY K 200
REMARK 465 SER K 201
REMARK 465 GLY L 201
REMARK 465 SER L 202
REMARK 465 THR L 203
REMARK 465 PRO L 204
REMARK 465 ARG M 1
REMARK 465 HIS N 213
REMARK 465 MET N 214
REMARK 465 ILE N 215
REMARK 465 SER N 216
REMARK 465 GLY N 217
REMARK 465 PHE N 218
REMARK 465 GLU N 219
REMARK 465 MET O 1
REMARK 465 SER O 2
REMARK 465 ALA O 243
REMARK 465 GLU O 244
REMARK 465 ARG O 245
REMARK 465 ASP O 246
REMARK 465 MET P 0
REMARK 465 ALA P 1
REMARK 465 GLU P 2
REMARK 465 ILE P 232
REMARK 465 ALA P 233
REMARK 465 MET Q 1
REMARK 465 ARG Q 249
REMARK 465 GLU Q 250
REMARK 465 LYS Q 251
REMARK 465 LYS Q 252
REMARK 465 GLU Q 253
REMARK 465 LYS Q 254
REMARK 465 GLU Q 255
REMARK 465 GLN Q 256
REMARK 465 LYS Q 257
REMARK 465 GLU Q 258
REMARK 465 LYS Q 259
REMARK 465 ASP Q 260
REMARK 465 LYS Q 261
REMARK 465 MET R 1
REMARK 465 LYS R 234
REMARK 465 GLU R 235
REMARK 465 LYS R 236
REMARK 465 GLU R 237
REMARK 465 GLU R 238
REMARK 465 ASN R 239
REMARK 465 GLU R 240
REMARK 465 LYS R 241
REMARK 465 LYS R 242
REMARK 465 LYS R 243
REMARK 465 GLN R 244
REMARK 465 LYS R 245
REMARK 465 LYS R 246
REMARK 465 ALA R 247
REMARK 465 SER R 248
REMARK 465 MET S 1
REMARK 465 PHE S 2
REMARK 465 LEU S 3
REMARK 465 THR S 4
REMARK 465 ARG S 5
REMARK 465 SER S 6
REMARK 465 GLU S 7
REMARK 465 TYR S 8
REMARK 465 MET T 1
REMARK 465 PHE T 2
REMARK 465 ARG T 3
REMARK 465 GLU T 237
REMARK 465 GLU T 238
REMARK 465 ARG T 239
REMARK 465 PRO T 240
REMARK 465 GLN T 241
REMARK 465 ARG T 242
REMARK 465 LYS T 243
REMARK 465 ALA T 244
REMARK 465 GLN T 245
REMARK 465 PRO T 246
REMARK 465 ALA T 247
REMARK 465 GLN T 248
REMARK 465 PRO T 249
REMARK 465 ALA T 250
REMARK 465 ASP T 251
REMARK 465 GLU T 252
REMARK 465 PRO T 253
REMARK 465 ALA T 254
REMARK 465 GLU T 255
REMARK 465 LYS T 256
REMARK 465 ALA T 257
REMARK 465 ASP T 258
REMARK 465 GLU T 259
REMARK 465 PRO T 260
REMARK 465 MET T 261
REMARK 465 GLU T 262
REMARK 465 HIS T 263
REMARK 465 MET U 0
REMARK 465 SER U 1
REMARK 465 SER U 2
REMARK 465 ILE U 3
REMARK 465 GLY U 4
REMARK 465 THR U 5
REMARK 465 GLU U 245
REMARK 465 GLU U 246
REMARK 465 ASP U 247
REMARK 465 GLU U 248
REMARK 465 SER U 249
REMARK 465 ASP U 250
REMARK 465 ASP U 251
REMARK 465 ASP U 252
REMARK 465 ASN U 253
REMARK 465 MET U 254
REMARK 465 PRO V 203
REMARK 465 PRO V 204
REMARK 465 ALA V 205
REMARK 465 ILE W 221
REMARK 465 GLU W 222
REMARK 465 VAL W 223
REMARK 465 LEU W 224
REMARK 465 GLU W 225
REMARK 465 GLU W 226
REMARK 465 THR W 227
REMARK 465 VAL W 228
REMARK 465 GLN W 229
REMARK 465 THR W 230
REMARK 465 MET W 231
REMARK 465 ASP W 232
REMARK 465 THR W 233
REMARK 465 SER W 234
REMARK 465 MET X 0
REMARK 465 PRO Y 197
REMARK 465 LYS Y 198
REMARK 465 GLN Y 199
REMARK 465 GLY Y 200
REMARK 465 SER Y 201
REMARK 465 GLY Z 201
REMARK 465 SER Z 202
REMARK 465 THR Z 203
REMARK 465 PRO Z 204
REMARK 465 ARG a 1
REMARK 465 HIS b 213
REMARK 465 MET b 214
REMARK 465 ILE b 215
REMARK 465 SER b 216
REMARK 465 GLY b 217
REMARK 465 PHE b 218
REMARK 465 GLU b 219
REMARK 470
REMARK 470 MISSING ATOM
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;
REMARK 470 I=INSERTION CODE):
REMARK 470 M RES CSSEQI ATOMS
REMARK 470 ARG A 3 CG CD NE CZ NH1 NH2
REMARK 470 SER A 6 OG
REMARK 470 ASP A 46 CG OD1 OD2
REMARK 470 CYS A 47 SG
REMARK 470 VAL A 56 CG1 CG2
REMARK 470 PRO A 57 CG CD
REMARK 470 ASP A 58 CG OD1 OD2
REMARK 470 LYS A 59 CG CD CE NZ
REMARK 470 SER A 64 OG
REMARK 470 GLU A 74 CG CD OE1 OE2
REMARK 470 GLU A 97 CG CD OE1 OE2
REMARK 470 GLU A 108 CG CD OE1 OE2
REMARK 470 GLU A 130 CG CD OE1 OE2
REMARK 470 ASP A 144 CG OD1 OD2
REMARK 470 GLU A 145 CG CD OE1 OE2
REMARK 470 GLU A 146 CG CD OE1 OE2
REMARK 470 GLN A 147 CG CD OE1 NE2
REMARK 470 GLU A 180 CG CD OE1 OE2
REMARK 470 VAL A 183 CG1 CG2
REMARK 470 LYS A 184 CG CD CE NZ
REMARK 470 LYS A 185 CG CD CE NZ
REMARK 470 LYS A 186 CG CD CE NZ
REMARK 470 PHE A 187 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 ASP A 188 CG OD1 OD2
REMARK 470 TRP A 189 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP A 189 CZ3 CH2
REMARK 470 THR A 190 OG1 CG2
REMARK 470 GLU A 196 CG CD OE1 OE2
REMARK 470 LEU A 206 CG CD1 CD2
REMARK 470 SER A 207 OG
REMARK 470 ILE A 208 CG1 CG2 CD1
REMARK 470 ASP A 209 CG OD1 OD2
REMARK 470 PRO A 212 CG CD
REMARK 470 SER A 213 OG
REMARK 470 GLU A 214 CG CD OE1 OE2
REMARK 470 THR A 221 OG1 CG2
REMARK 470 GLU A 223 CG CD OE1 OE2
REMARK 470 GLU A 232 CG CD OE1 OE2
REMARK 470 GLU A 234 CG CD OE1 OE2
REMARK 470 ASP A 236 CG OD1 OD2
REMARK 470 LEU A 239 CG CD1 CD2
REMARK 470 VAL A 240 CG1 CG2
REMARK 470 LEU A 242 CG CD1 CD2
REMARK 470 ARG B 3 CG CD NE CZ NH1 NH2
REMARK 470 GLU B 22 CG CD OE1 OE2
REMARK 470 LYS B 52 CG CD CE NZ
REMARK 470 SER B 53 OG
REMARK 470 ILE B 54 CG1 CG2 CD1
REMARK 470 GLU B 58 CG CD OE1 OE2
REMARK 470 ARG B 59 CG CD NE CZ NH1 NH2
REMARK 470 SER B 60 OG
REMARK 470 GLU B 65 CG CD OE1 OE2
REMARK 470 LYS B 69 CG CD CE NZ
REMARK 470 GLU B 119 CG CD OE1 OE2
REMARK 470 ASN B 139 CG OD1 ND2
REMARK 470 GLU B 140 CG CD OE1 OE2
REMARK 470 ASP B 149 CG OD1 OD2
REMARK 470 LYS B 164 CG CD CE NZ
REMARK 470 ASN B 165 CG OD1 ND2
REMARK 470 VAL B 167 CG1 CG2
REMARK 470 ASN B 168 CG OD1 ND2
REMARK 470 THR B 171 OG1 CG2
REMARK 470 GLU B 174 CG CD OE1 OE2
REMARK 470 LYS B 175 CG CD CE NZ
REMARK 470 ASN B 178 CG OD1 ND2
REMARK 470 GLU B 179 CG CD OE1 OE2
REMARK 470 ASP B 180 CG OD1 OD2
REMARK 470 GLU B 182 CG CD OE1 OE2
REMARK 470 GLU B 184 CG CD OE1 OE2
REMARK 470 ASP B 185 CG OD1 OD2
REMARK 470 GLU B 196 CG CD OE1 OE2
REMARK 470 SER B 197 OG
REMARK 470 GLU B 199 CG CD OE1 OE2
REMARK 470 GLN B 201 CG CD OE1 NE2
REMARK 470 THR B 203 OG1 CG2
REMARK 470 GLU B 204 CG CD OE1 OE2
REMARK 470 ASP B 205 CG OD1 OD2
REMARK 470 ASN B 206 CG OD1 ND2
REMARK 470 GLU B 214 CG CD OE1 OE2
REMARK 470 THR B 221 OG1 CG2
REMARK 470 ASP B 227 CG OD1 OD2
REMARK 470 SER C 13 OG
REMARK 470 GLU C 15 CG CD OE1 OE2
REMARK 470 GLU C 22 CG CD OE1 OE2
REMARK 470 GLU C 48 CG CD OE1 OE2
REMARK 470 ASN C 51 CG OD1 ND2
REMARK 470 ILE C 52 CG1 CG2 CD1
REMARK 470 LYS C 54 CG CD CE NZ
REMARK 470 ASP C 57 CG OD1 OD2
REMARK 470 VAL C 59 CG1 CG2
REMARK 470 PHE C 60 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 SER C 62 OG
REMARK 470 GLU C 63 CG CD OE1 OE2
REMARK 470 GLU C 70 CG CD OE1 OE2
REMARK 470 ASP C 71 CG OD1 OD2
REMARK 470 ASP C 82 CG OD1 OD2
REMARK 470 GLU C 89 CG CD OE1 OE2
REMARK 470 GLU C 103 CG CD OE1 OE2
REMARK 470 GLU C 108 CG CD OE1 OE2
REMARK 470 ASP C 151 CG OD1 OD2
REMARK 470 SER C 153 OG
REMARK 470 ASN C 166 CG OD1 ND2
REMARK 470 SER C 173 OG
REMARK 470 ASP C 178 CG OD1 OD2
REMARK 470 GLU C 181 CG CD OE1 OE2
REMARK 470 GLU C 183 CG CD OE1 OE2
REMARK 470 THR C 185 OG1 CG2
REMARK 470 ASP C 202 CG OD1 OD2
REMARK 470 VAL C 203 CG1 CG2
REMARK 470 SER C 204 OG
REMARK 470 LYS C 205 CG CD CE NZ
REMARK 470 SER C 207 OG
REMARK 470 LYS C 210 CG CD CE NZ
REMARK 470 GLU C 212 CG CD OE1 OE2
REMARK 470 GLU C 219 CG CD OE1 OE2
REMARK 470 ASN C 220 CG OD1 ND2
REMARK 470 LYS C 222 CG CD CE NZ
REMARK 470 LYS C 231 CG CD CE NZ
REMARK 470 GLU C 234 CG CD OE1 OE2
REMARK 470 GLN C 235 CG CD OE1 NE2
REMARK 470 LYS C 238 CG CD CE NZ
REMARK 470 LYS C 239 CG CD CE NZ
REMARK 470 GLU C 241 CG CD OE1 OE2
REMARK 470 GLU C 242 CG CD OE1 OE2
REMARK 470 GLU C 243 CG CD OE1 OE2
REMARK 470 GLU C 244 CG CD OE1 OE2
REMARK 470 LYS C 246 CG CD CE NZ
REMARK 470 GLU C 248 CG CD OE1 OE2
REMARK 470 SER D 2 OG
REMARK 470 ASP D 13 CG OD1 OD2
REMARK 470 GLU D 24 CG CD OE1 OE2
REMARK 470 LYS D 28 CG CD CE NZ
REMARK 470 SER D 30 OG
REMARK 470 ARG D 38 CG CD NE CZ NH1 NH2
REMARK 470 ASP D 39 CG OD1 OD2
REMARK 470 GLU D 46 CG CD OE1 OE2
REMARK 470 LYS D 48 CG CD CE NZ
REMARK 470 SER D 49 OG
REMARK 470 VAL D 50 CG1 CG2
REMARK 470 LYS D 52 CG CD CE NZ
REMARK 470 GLU D 56 CG CD OE1 OE2
REMARK 470 ASP D 100 CG OD1 OD2
REMARK 470 GLU D 105 CG CD OE1 OE2
REMARK 470 SER D 130 OG
REMARK 470 ASP D 137 CG OD1 OD2
REMARK 470 PHE D 138 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 ASP D 139 CG OD1 OD2
REMARK 470 THR D 141 OG1 CG2
REMARK 470 ASP D 148 CG OD1 OD2
REMARK 470 SER D 150 OG
REMARK 470 ASN D 159 CG OD1 ND2
REMARK 470 LYS D 166 CG CD CE NZ
REMARK 470 GLU D 170 CG CD OE1 OE2
REMARK 470 GLU D 173 CG CD OE1 OE2
REMARK 470 LYS D 174 CG CD CE NZ
REMARK 470 THR D 177 OG1 CG2
REMARK 470 ASP D 178 CG OD1 OD2
REMARK 470 GLU D 179 CG CD OE1 OE2
REMARK 470 ILE D 181 CG1 CG2 CD1
REMARK 470 GLU D 182 CG CD OE1 OE2
REMARK 470 THR D 183 OG1 CG2
REMARK 470 ASP D 184 CG OD1 OD2
REMARK 470 ASP D 185 CG OD1 OD2
REMARK 470 LEU D 186 CG CD1 CD2
REMARK 470 LYS D 189 CG CD CE NZ
REMARK 470 LYS D 193 CG CD CE NZ
REMARK 470 GLU D 197 CG CD OE1 OE2
REMARK 470 VAL D 198 CG1 CG2
REMARK 470 GLN D 200 CG CD OE1 NE2
REMARK 470 SER D 201 OG
REMARK 470 LYS D 204 CG CD CE NZ
REMARK 470 ASN D 205 CG OD1 ND2
REMARK 470 GLU D 207 CG CD OE1 OE2
REMARK 470 ASP D 214 CG OD1 OD2
REMARK 470 GLN D 215 CG CD OE1 NE2
REMARK 470 SER D 216 OG
REMARK 470 LYS D 218 CG CD CE NZ
REMARK 470 ASN D 221 CG OD1 ND2
REMARK 470 PRO D 222 CG CD
REMARK 470 GLU D 223 CG CD OE1 OE2
REMARK 470 GLU D 224 CG CD OE1 OE2
REMARK 470 ILE D 225 CG1 CG2 CD1
REMARK 470 GLU D 226 CG CD OE1 OE2
REMARK 470 LYS D 227 CG CD CE NZ
REMARK 470 VAL D 229 CG1 CG2
REMARK 470 GLU D 231 CG CD OE1 OE2
REMARK 470 ILE D 232 CG1 CG2 CD1
REMARK 470 GLU D 233 CG CD OE1 OE2
REMARK 470 ASP E 9 CG OD1 OD2
REMARK 470 SER E 16 OG
REMARK 470 GLU E 44 CG CD OE1 OE2
REMARK 470 THR E 55 OG1 CG2
REMARK 470 SER E 56 OG
REMARK 470 SER E 62 OG
REMARK 470 GLU E 65 CG CD OE1 OE2
REMARK 470 ASP E 71 CG OD1 OD2
REMARK 470 LYS E 86 CG CD CE NZ
REMARK 470 ASP E 90 CG OD1 OD2
REMARK 470 LYS E 91 CG CD CE NZ
REMARK 470 GLU E 95 CG CD OE1 OE2
REMARK 470 GLU E 105 CG CD OE1 OE2
REMARK 470 GLU E 110 CG CD OE1 OE2
REMARK 470 GLN E 122 CG CD OE1 NE2
REMARK 470 GLU E 126 CG CD OE1 OE2
REMARK 470 ASP E 127 CG OD1 OD2
REMARK 470 ASP E 129 CG OD1 OD2
REMARK 470 PRO E 130 CG CD
REMARK 470 SER E 134 OG
REMARK 470 ASP E 147 CG OD1 OD2
REMARK 470 GLU E 148 CG CD OE1 OE2
REMARK 470 ASP E 157 CG OD1 OD2
REMARK 470 GLU E 175 CG CD OE1 OE2
REMARK 470 SER E 179 OG
REMARK 470 GLU E 183 CG CD OE1 OE2
REMARK 470 LYS E 187 CG CD CE NZ
REMARK 470 GLU E 193 CG CD OE1 OE2
REMARK 470 GLU E 207 CG CD OE1 OE2
REMARK 470 GLU E 208 CG CD OE1 OE2
REMARK 470 LYS E 209 CG CD CE NZ
REMARK 470 THR E 213 OG1 CG2
REMARK 470 GLN E 224 CG CD OE1 NE2
REMARK 470 GLU E 232 CG CD OE1 OE2
REMARK 470 LYS E 239 CG CD CE NZ
REMARK 470 ASP E 240 CG OD1 OD2
REMARK 470 ILE E 241 CG1 CG2 CD1
REMARK 470 ASN F 4 CG OD1 ND2
REMARK 470 LYS F 30 CG CD CE NZ
REMARK 470 GLN F 31 CG CD OE1 NE2
REMARK 470 LYS F 41 CG CD CE NZ
REMARK 470 THR F 42 OG1 CG2
REMARK 470 ARG F 51 CG CD NE CZ NH1 NH2
REMARK 470 GLN F 53 CG CD OE1 NE2
REMARK 470 SER F 54 OG
REMARK 470 GLU F 55 CG CD OE1 OE2
REMARK 470 ASP F 67 CG OD1 OD2
REMARK 470 ASP F 80 CG OD1 OD2
REMARK 470 GLU F 91 CG CD OE1 OE2
REMARK 470 SER F 110 OG
REMARK 470 ASP F 138 CG OD1 OD2
REMARK 470 ASP F 139 CG OD1 OD2
REMARK 470 MET F 140 CG SD CE
REMARK 470 CYS F 148 SG
REMARK 470 ASP F 155 CG OD1 OD2
REMARK 470 SER F 167 OG
REMARK 470 GLU F 173 CG CD OE1 OE2
REMARK 470 SER F 177 OG
REMARK 470 GLU F 181 CG CD OE1 OE2
REMARK 470 ASN F 183 CG OD1 ND2
REMARK 470 ASN F 185 CG OD1 ND2
REMARK 470 GLU F 186 CG CD OE1 OE2
REMARK 470 GLU F 197 CG CD OE1 OE2
REMARK 470 GLU F 202 CG CD OE1 OE2
REMARK 470 GLN F 203 CG CD OE1 NE2
REMARK 470 ASP F 204 CG OD1 OD2
REMARK 470 THR F 206 OG1 CG2
REMARK 470 LYS F 208 CG CD CE NZ
REMARK 470 LYS F 217 CG CD CE NZ
REMARK 470 ASP F 218 CG OD1 OD2
REMARK 470 GLU F 220 CG CD OE1 OE2
REMARK 470 ASP F 225 CG OD1 OD2
REMARK 470 ASP F 226 CG OD1 OD2
REMARK 470 ASP F 227 CG OD1 OD2
REMARK 470 GLU F 234 CG CD OE1 OE2
REMARK 470 LEU F 236 CG CD1 CD2
REMARK 470 SER G 15 OG
REMARK 470 GLU G 31 CG CD OE1 OE2
REMARK 470 LYS G 42 CG CD CE NZ
REMARK 470 ASP G 43 CG OD1 OD2
REMARK 470 LYS G 56 CG CD CE NZ
REMARK 470 GLU G 60 CG CD OE1 OE2
REMARK 470 SER G 62 OG
REMARK 470 ASN G 63 CG OD1 ND2
REMARK 470 LYS G 64 CG CD CE NZ
REMARK 470 ASP G 89 CG OD1 OD2
REMARK 470 GLU G 94 CG CD OE1 OE2
REMARK 470 SER G 141 OG
REMARK 470 ASN G 143 CG OD1 ND2
REMARK 470 ASP G 144 CG OD1 OD2
REMARK 470 ASP G 152 CG OD1 OD2
REMARK 470 CYS G 163 SG
REMARK 470 GLU G 177 CG CD OE1 OE2
REMARK 470 GLU G 183 CG CD OE1 OE2
REMARK 470 ASP G 188 CG OD1 OD2
REMARK 470 LYS G 191 CG CD CE NZ
REMARK 470 GLU G 203 CG CD OE1 OE2
REMARK 470 VAL G 204 CG1 CG2
REMARK 470 LYS G 205 CG CD CE NZ
REMARK 470 LYS G 207 CG CD CE NZ
REMARK 470 GLU G 210 CG CD OE1 OE2
REMARK 470 GLU G 212 CG CD OE1 OE2
REMARK 470 SER G 214 OG
REMARK 470 GLU G 218 CG CD OE1 OE2
REMARK 470 ARG G 223 CG CD NE CZ NH1 NH2
REMARK 470 ASP G 230 CG OD1 OD2
REMARK 470 GLU G 233 CG CD OE1 OE2
REMARK 470 GLU G 234 CG CD OE1 OE2
REMARK 470 GLU G 241 CG CD OE1 OE2
REMARK 470 SER G 242 OG
REMARK 470 LYS G 244 CG CD CE NZ
REMARK 470 ASP H 9 CG OD1 OD2
REMARK 470 ASP H 32 CG OD1 OD2
REMARK 470 THR H 35 OG1 CG2
REMARK 470 ASP H 39 CG OD1 OD2
REMARK 470 ASN H 71 CG OD1 ND2
REMARK 470 GLU H 72 CG CD OE1 OE2
REMARK 470 SER H 130 OG
REMARK 470 ASP H 140 CG OD1 OD2
REMARK 470 GLU H 145 CG CD OE1 OE2
REMARK 470 GLU H 150 CG CD OE1 OE2
REMARK 470 SER H 182 OG
REMARK 470 GLU H 185 CG CD OE1 OE2
REMARK 470 ASP H 192 CG OD1 OD2
REMARK 470 GLN H 193 CG CD OE1 NE2
REMARK 470 VAL H 199 CG1 CG2
REMARK 470 THR H 201 OG1 CG2
REMARK 470 LEU H 202 CG CD1 CD2
REMARK 470 GLU I 22 CG CD OE1 OE2
REMARK 470 ASP I 28 CG OD1 OD2
REMARK 470 CYS I 31 SG
REMARK 470 MET I 54 CG SD CE
REMARK 470 GLU I 64 CG CD OE1 OE2
REMARK 470 ASP I 120 CG OD1 OD2
REMARK 470 ASP I 145 CG OD1 OD2
REMARK 470 GLU I 147 CG CD OE1 OE2
REMARK 470 GLU I 149 CG CD OE1 OE2
REMARK 470 GLU I 150 CG CD OE1 OE2
REMARK 470 ASN I 153 CG OD1 ND2
REMARK 470 GLU I 157 CG CD OE1 OE2
REMARK 470 LYS I 180 CG CD CE NZ
REMARK 470 ASN I 181 CG OD1 ND2
REMARK 470 ASP I 184 CG OD1 OD2
REMARK 470 ASN I 193 CG OD1 ND2
REMARK 470 LEU I 199 CG CD1 CD2
REMARK 470 ARG I 201 CG CD NE CZ NH1 NH2
REMARK 470 ARG I 203 CG CD NE CZ NH1 NH2
REMARK 470 CYS I 204 SG
REMARK 470 GLU I 205 CG CD OE1 OE2
REMARK 470 LYS I 206 CG CD CE NZ
REMARK 470 THR I 208 OG1 CG2
REMARK 470 GLU I 220 CG CD OE1 OE2
REMARK 470 SER J 1 OG
REMARK 470 LYS J 16 CG CD CE NZ
REMARK 470 GLN J 30 CG CD OE1 NE2
REMARK 470 ASP J 37 CG OD1 OD2
REMARK 470 ASP J 46 CG OD1 OD2
REMARK 470 GLU J 74 CG CD OE1 OE2
REMARK 470 GLU J 77 CG CD OE1 OE2
REMARK 470 GLU J 96 CG CD OE1 OE2
REMARK 470 ASP J 124 CG OD1 OD2
REMARK 470 ASP J 133 CG OD1 OD2
REMARK 470 ASP J 134 CG OD1 OD2
REMARK 470 THR J 140 OG1 CG2
REMARK 470 CYS J 149 SG
REMARK 470 GLU J 154 CG CD OE1 OE2
REMARK 470 ASP J 158 CG OD1 OD2
REMARK 470 ASP J 160 CG OD1 OD2
REMARK 470 GLU J 190 CG CD OE1 OE2
REMARK 470 LYS J 191 CG CD CE NZ
REMARK 470 MET K 1 CG SD CE
REMARK 470 GLU K 2 CG CD OE1 OE2
REMARK 470 SER K 23 OG
REMARK 470 ASN K 24 CG OD1 ND2
REMARK 470 ILE K 25 CG1 CG2 CD1
REMARK 470 VAL K 26 CG1 CG2
REMARK 470 ASP K 30 CG OD1 OD2
REMARK 470 ASP K 33 CG OD1 OD2
REMARK 470 GLU K 40 CG CD OE1 OE2
REMARK 470 GLU K 49 CG CD OE1 OE2
REMARK 470 GLU K 58 CG CD OE1 OE2
REMARK 470 GLU K 74 CG CD OE1 OE2
REMARK 470 ARG K 95 CG CD NE CZ NH1 NH2
REMARK 470 GLU K 109 CG CD OE1 OE2
REMARK 470 SER K 152 OG
REMARK 470 ARG K 155 CG CD NE CZ NH1 NH2
REMARK 470 LYS K 169 CG CD CE NZ
REMARK 470 ASP K 190 CG OD1 OD2
REMARK 470 ASP K 192 CG OD1 OD2
REMARK 470 SER L 28 OG
REMARK 470 LYS L 71 CG CD CE NZ
REMARK 470 GLU L 72 CG CD OE1 OE2
REMARK 470 LYS L 81 CG CD CE NZ
REMARK 470 SER L 96 OG
REMARK 470 ASP L 105 CG OD1 OD2
REMARK 470 LYS L 106 CG CD CE NZ
REMARK 470 ASP L 115 CG OD1 OD2
REMARK 470 GLU L 117 CG CD OE1 OE2
REMARK 470 SER L 144 OG
REMARK 470 ASP L 146 CG OD1 OD2
REMARK 470 GLU L 148 CG CD OE1 OE2
REMARK 470 GLU L 150 CG CD OE1 OE2
REMARK 470 GLU L 181 CG CD OE1 OE2
REMARK 470 ASP L 190 CG OD1 OD2
REMARK 470 ASP L 194 CG OD1 OD2
REMARK 470 GLU L 197 CG CD OE1 OE2
REMARK 470 SER L 200 OG
REMARK 470 GLU M 18 CG CD OE1 OE2
REMARK 470 ASP M 19 CG OD1 OD2
REMARK 470 GLU M 31 CG CD OE1 OE2
REMARK 470 ASP M 39 CG OD1 OD2
REMARK 470 ASP M 48 CG OD1 OD2
REMARK 470 GLU M 69 CG CD OE1 OE2
REMARK 470 GLU M 115 CG CD OE1 OE2
REMARK 470 GLU M 116 CG CD OE1 OE2
REMARK 470 ASP M 125 CG OD1 OD2
REMARK 470 ASP M 133 CG OD1 OD2
REMARK 470 SER M 140 OG
REMARK 470 ASP M 150 CG OD1 OD2
REMARK 470 ASN M 160 CG OD1 ND2
REMARK 470 VAL M 161 CG1 CG2
REMARK 470 GLU M 162 CG CD OE1 OE2
REMARK 470 GLU M 184 CG CD OE1 OE2
REMARK 470 ASP M 191 CG OD1 OD2
REMARK 470 SER M 209 OG
REMARK 470 ASP M 213 CG OD1 OD2
REMARK 470 THR N 1 OG1 CG2
REMARK 470 GLN N 2 CG CD OE1 NE2
REMARK 470 ASN N 3 CG OD1 ND2
REMARK 470 GLU N 17 CG CD OE1 OE2
REMARK 470 SER N 40 OG
REMARK 470 GLU N 74 CG CD OE1 OE2
REMARK 470 GLU N 75 CG CD OE1 OE2
REMARK 470 SER N 82 OG
REMARK 470 LYS N 102 CG CD CE NZ
REMARK 470 ASP N 117 CG OD1 OD2
REMARK 470 ASP N 126 CG OD1 OD2
REMARK 470 GLU N 133 CG CD OE1 OE2
REMARK 470 GLU N 152 CG CD OE1 OE2
REMARK 470 GLU N 155 CG CD OE1 OE2
REMARK 470 ASP N 167 CG OD1 OD2
REMARK 470 GLU N 194 CG CD OE1 OE2
REMARK 470 LYS N 195 CG CD CE NZ
REMARK 470 GLU N 198 CG CD OE1 OE2
REMARK 470 SER N 204 OG
REMARK 470 THR N 205 OG1 CG2
REMARK 470 GLU N 206 CG CD OE1 OE2
REMARK 470 THR N 207 OG1 CG2
REMARK 470 ASN N 208 CG OD1 ND2
REMARK 470 TRP N 209 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP N 209 CZ3 CH2
REMARK 470 ASP N 210 CG OD1 OD2
REMARK 470 ILE N 211 CG1 CG2 CD1
REMARK 470 ARG O 3 CG CD NE CZ NH1 NH2
REMARK 470 SER O 6 OG
REMARK 470 ASP O 46 CG OD1 OD2
REMARK 470 CYS O 47 SG
REMARK 470 VAL O 56 CG1 CG2
REMARK 470 PRO O 57 CG CD
REMARK 470 ASP O 58 CG OD1 OD2
REMARK 470 LYS O 59 CG CD CE NZ
REMARK 470 SER O 64 OG
REMARK 470 GLU O 74 CG CD OE1 OE2
REMARK 470 GLU O 97 CG CD OE1 OE2
REMARK 470 GLU O 108 CG CD OE1 OE2
REMARK 470 GLU O 130 CG CD OE1 OE2
REMARK 470 ASP O 144 CG OD1 OD2
REMARK 470 GLU O 145 CG CD OE1 OE2
REMARK 470 GLU O 146 CG CD OE1 OE2
REMARK 470 GLN O 147 CG CD OE1 NE2
REMARK 470 GLU O 180 CG CD OE1 OE2
REMARK 470 VAL O 183 CG1 CG2
REMARK 470 LYS O 184 CG CD CE NZ
REMARK 470 LYS O 185 CG CD CE NZ
REMARK 470 LYS O 186 CG CD CE NZ
REMARK 470 PHE O 187 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 ASP O 188 CG OD1 OD2
REMARK 470 TRP O 189 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP O 189 CZ3 CH2
REMARK 470 THR O 190 OG1 CG2
REMARK 470 GLU O 196 CG CD OE1 OE2
REMARK 470 LEU O 206 CG CD1 CD2
REMARK 470 SER O 207 OG
REMARK 470 ILE O 208 CG1 CG2 CD1
REMARK 470 ASP O 209 CG OD1 OD2
REMARK 470 PRO O 212 CG CD
REMARK 470 SER O 213 OG
REMARK 470 GLU O 214 CG CD OE1 OE2
REMARK 470 THR O 221 OG1 CG2
REMARK 470 GLU O 223 CG CD OE1 OE2
REMARK 470 GLU O 232 CG CD OE1 OE2
REMARK 470 GLU O 234 CG CD OE1 OE2
REMARK 470 ASP O 236 CG OD1 OD2
REMARK 470 LEU O 239 CG CD1 CD2
REMARK 470 VAL O 240 CG1 CG2
REMARK 470 LEU O 242 CG CD1 CD2
REMARK 470 ARG P 3 CG CD NE CZ NH1 NH2
REMARK 470 GLU P 22 CG CD OE1 OE2
REMARK 470 LYS P 52 CG CD CE NZ
REMARK 470 SER P 53 OG
REMARK 470 ILE P 54 CG1 CG2 CD1
REMARK 470 GLU P 58 CG CD OE1 OE2
REMARK 470 ARG P 59 CG CD NE CZ NH1 NH2
REMARK 470 SER P 60 OG
REMARK 470 GLU P 65 CG CD OE1 OE2
REMARK 470 LYS P 69 CG CD CE NZ
REMARK 470 GLU P 119 CG CD OE1 OE2
REMARK 470 ASN P 139 CG OD1 ND2
REMARK 470 GLU P 140 CG CD OE1 OE2
REMARK 470 ASP P 149 CG OD1 OD2
REMARK 470 LYS P 164 CG CD CE NZ
REMARK 470 ASN P 165 CG OD1 ND2
REMARK 470 VAL P 167 CG1 CG2
REMARK 470 ASN P 168 CG OD1 ND2
REMARK 470 THR P 171 OG1 CG2
REMARK 470 GLU P 174 CG CD OE1 OE2
REMARK 470 LYS P 175 CG CD CE NZ
REMARK 470 ASN P 178 CG OD1 ND2
REMARK 470 GLU P 179 CG CD OE1 OE2
REMARK 470 ASP P 180 CG OD1 OD2
REMARK 470 GLU P 182 CG CD OE1 OE2
REMARK 470 GLU P 184 CG CD OE1 OE2
REMARK 470 ASP P 185 CG OD1 OD2
REMARK 470 GLU P 196 CG CD OE1 OE2
REMARK 470 SER P 197 OG
REMARK 470 GLU P 199 CG CD OE1 OE2
REMARK 470 GLN P 201 CG CD OE1 NE2
REMARK 470 THR P 203 OG1 CG2
REMARK 470 GLU P 204 CG CD OE1 OE2
REMARK 470 ASP P 205 CG OD1 OD2
REMARK 470 ASN P 206 CG OD1 ND2
REMARK 470 GLU P 214 CG CD OE1 OE2
REMARK 470 THR P 221 OG1 CG2
REMARK 470 ASP P 227 CG OD1 OD2
REMARK 470 SER Q 13 OG
REMARK 470 GLU Q 15 CG CD OE1 OE2
REMARK 470 GLU Q 22 CG CD OE1 OE2
REMARK 470 GLU Q 48 CG CD OE1 OE2
REMARK 470 ASN Q 51 CG OD1 ND2
REMARK 470 ILE Q 52 CG1 CG2 CD1
REMARK 470 LYS Q 54 CG CD CE NZ
REMARK 470 ASP Q 57 CG OD1 OD2
REMARK 470 VAL Q 59 CG1 CG2
REMARK 470 PHE Q 60 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 SER Q 62 OG
REMARK 470 GLU Q 63 CG CD OE1 OE2
REMARK 470 GLU Q 70 CG CD OE1 OE2
REMARK 470 ASP Q 71 CG OD1 OD2
REMARK 470 ASP Q 82 CG OD1 OD2
REMARK 470 GLU Q 89 CG CD OE1 OE2
REMARK 470 GLU Q 103 CG CD OE1 OE2
REMARK 470 GLU Q 108 CG CD OE1 OE2
REMARK 470 ASP Q 151 CG OD1 OD2
REMARK 470 SER Q 153 OG
REMARK 470 ASN Q 166 CG OD1 ND2
REMARK 470 SER Q 173 OG
REMARK 470 ASP Q 178 CG OD1 OD2
REMARK 470 GLU Q 181 CG CD OE1 OE2
REMARK 470 GLU Q 183 CG CD OE1 OE2
REMARK 470 THR Q 185 OG1 CG2
REMARK 470 ASP Q 202 CG OD1 OD2
REMARK 470 VAL Q 203 CG1 CG2
REMARK 470 SER Q 204 OG
REMARK 470 LYS Q 205 CG CD CE NZ
REMARK 470 SER Q 207 OG
REMARK 470 LYS Q 210 CG CD CE NZ
REMARK 470 GLU Q 212 CG CD OE1 OE2
REMARK 470 GLU Q 219 CG CD OE1 OE2
REMARK 470 ASN Q 220 CG OD1 ND2
REMARK 470 LYS Q 222 CG CD CE NZ
REMARK 470 LYS Q 231 CG CD CE NZ
REMARK 470 GLU Q 234 CG CD OE1 OE2
REMARK 470 GLN Q 235 CG CD OE1 NE2
REMARK 470 LYS Q 238 CG CD CE NZ
REMARK 470 LYS Q 239 CG CD CE NZ
REMARK 470 GLU Q 241 CG CD OE1 OE2
REMARK 470 GLU Q 242 CG CD OE1 OE2
REMARK 470 GLU Q 243 CG CD OE1 OE2
REMARK 470 GLU Q 244 CG CD OE1 OE2
REMARK 470 LYS Q 246 CG CD CE NZ
REMARK 470 GLU Q 248 CG CD OE1 OE2
REMARK 470 SER R 2 OG
REMARK 470 ASP R 13 CG OD1 OD2
REMARK 470 GLU R 24 CG CD OE1 OE2
REMARK 470 LYS R 28 CG CD CE NZ
REMARK 470 SER R 30 OG
REMARK 470 ARG R 38 CG CD NE CZ NH1 NH2
REMARK 470 ASP R 39 CG OD1 OD2
REMARK 470 GLU R 46 CG CD OE1 OE2
REMARK 470 LYS R 48 CG CD CE NZ
REMARK 470 SER R 49 OG
REMARK 470 VAL R 50 CG1 CG2
REMARK 470 LYS R 52 CG CD CE NZ
REMARK 470 GLU R 56 CG CD OE1 OE2
REMARK 470 ASP R 100 CG OD1 OD2
REMARK 470 GLU R 105 CG CD OE1 OE2
REMARK 470 SER R 130 OG
REMARK 470 ASP R 137 CG OD1 OD2
REMARK 470 PHE R 138 CG CD1 CD2 CE1 CE2 CZ
REMARK 470 ASP R 139 CG OD1 OD2
REMARK 470 THR R 141 OG1 CG2
REMARK 470 ASP R 148 CG OD1 OD2
REMARK 470 SER R 150 OG
REMARK 470 ASN R 159 CG OD1 ND2
REMARK 470 LYS R 166 CG CD CE NZ
REMARK 470 GLU R 170 CG CD OE1 OE2
REMARK 470 GLU R 173 CG CD OE1 OE2
REMARK 470 LYS R 174 CG CD CE NZ
REMARK 470 THR R 177 OG1 CG2
REMARK 470 ASP R 178 CG OD1 OD2
REMARK 470 GLU R 179 CG CD OE1 OE2
REMARK 470 ILE R 181 CG1 CG2 CD1
REMARK 470 GLU R 182 CG CD OE1 OE2
REMARK 470 THR R 183 OG1 CG2
REMARK 470 ASP R 184 CG OD1 OD2
REMARK 470 ASP R 185 CG OD1 OD2
REMARK 470 LEU R 186 CG CD1 CD2
REMARK 470 LYS R 189 CG CD CE NZ
REMARK 470 LYS R 193 CG CD CE NZ
REMARK 470 GLU R 197 CG CD OE1 OE2
REMARK 470 VAL R 198 CG1 CG2
REMARK 470 GLN R 200 CG CD OE1 NE2
REMARK 470 SER R 201 OG
REMARK 470 LYS R 204 CG CD CE NZ
REMARK 470 ASN R 205 CG OD1 ND2
REMARK 470 GLU R 207 CG CD OE1 OE2
REMARK 470 ASP R 214 CG OD1 OD2
REMARK 470 GLN R 215 CG CD OE1 NE2
REMARK 470 SER R 216 OG
REMARK 470 LYS R 218 CG CD CE NZ
REMARK 470 ASN R 221 CG OD1 ND2
REMARK 470 PRO R 222 CG CD
REMARK 470 GLU R 223 CG CD OE1 OE2
REMARK 470 GLU R 224 CG CD OE1 OE2
REMARK 470 ILE R 225 CG1 CG2 CD1
REMARK 470 GLU R 226 CG CD OE1 OE2
REMARK 470 LYS R 227 CG CD CE NZ
REMARK 470 VAL R 229 CG1 CG2
REMARK 470 GLU R 231 CG CD OE1 OE2
REMARK 470 ILE R 232 CG1 CG2 CD1
REMARK 470 GLU R 233 CG CD OE1 OE2
REMARK 470 ASP S 9 CG OD1 OD2
REMARK 470 SER S 16 OG
REMARK 470 GLU S 44 CG CD OE1 OE2
REMARK 470 THR S 55 OG1 CG2
REMARK 470 SER S 56 OG
REMARK 470 SER S 62 OG
REMARK 470 GLU S 65 CG CD OE1 OE2
REMARK 470 ASP S 71 CG OD1 OD2
REMARK 470 LYS S 86 CG CD CE NZ
REMARK 470 ASP S 90 CG OD1 OD2
REMARK 470 LYS S 91 CG CD CE NZ
REMARK 470 GLU S 95 CG CD OE1 OE2
REMARK 470 GLU S 105 CG CD OE1 OE2
REMARK 470 GLU S 110 CG CD OE1 OE2
REMARK 470 GLN S 122 CG CD OE1 NE2
REMARK 470 GLU S 126 CG CD OE1 OE2
REMARK 470 ASP S 127 CG OD1 OD2
REMARK 470 ASP S 129 CG OD1 OD2
REMARK 470 PRO S 130 CG CD
REMARK 470 SER S 134 OG
REMARK 470 ASP S 147 CG OD1 OD2
REMARK 470 GLU S 148 CG CD OE1 OE2
REMARK 470 ASP S 157 CG OD1 OD2
REMARK 470 GLU S 175 CG CD OE1 OE2
REMARK 470 SER S 179 OG
REMARK 470 GLU S 183 CG CD OE1 OE2
REMARK 470 LYS S 187 CG CD CE NZ
REMARK 470 GLU S 193 CG CD OE1 OE2
REMARK 470 GLU S 207 CG CD OE1 OE2
REMARK 470 GLU S 208 CG CD OE1 OE2
REMARK 470 LYS S 209 CG CD CE NZ
REMARK 470 THR S 213 OG1 CG2
REMARK 470 GLN S 224 CG CD OE1 NE2
REMARK 470 GLU S 232 CG CD OE1 OE2
REMARK 470 LYS S 239 CG CD CE NZ
REMARK 470 ASP S 240 CG OD1 OD2
REMARK 470 ILE S 241 CG1 CG2 CD1
REMARK 470 ASN T 4 CG OD1 ND2
REMARK 470 LYS T 30 CG CD CE NZ
REMARK 470 GLN T 31 CG CD OE1 NE2
REMARK 470 LYS T 41 CG CD CE NZ
REMARK 470 THR T 42 OG1 CG2
REMARK 470 ARG T 51 CG CD NE CZ NH1 NH2
REMARK 470 GLN T 53 CG CD OE1 NE2
REMARK 470 SER T 54 OG
REMARK 470 GLU T 55 CG CD OE1 OE2
REMARK 470 ASP T 67 CG OD1 OD2
REMARK 470 ASP T 80 CG OD1 OD2
REMARK 470 GLU T 91 CG CD OE1 OE2
REMARK 470 SER T 110 OG
REMARK 470 ASP T 138 CG OD1 OD2
REMARK 470 ASP T 139 CG OD1 OD2
REMARK 470 MET T 140 CG SD CE
REMARK 470 CYS T 148 SG
REMARK 470 ASP T 155 CG OD1 OD2
REMARK 470 SER T 167 OG
REMARK 470 GLU T 173 CG CD OE1 OE2
REMARK 470 SER T 177 OG
REMARK 470 GLU T 181 CG CD OE1 OE2
REMARK 470 ASN T 183 CG OD1 ND2
REMARK 470 ASN T 185 CG OD1 ND2
REMARK 470 GLU T 186 CG CD OE1 OE2
REMARK 470 GLU T 197 CG CD OE1 OE2
REMARK 470 GLU T 202 CG CD OE1 OE2
REMARK 470 GLN T 203 CG CD OE1 NE2
REMARK 470 ASP T 204 CG OD1 OD2
REMARK 470 THR T 206 OG1 CG2
REMARK 470 LYS T 208 CG CD CE NZ
REMARK 470 LYS T 217 CG CD CE NZ
REMARK 470 ASP T 218 CG OD1 OD2
REMARK 470 GLU T 220 CG CD OE1 OE2
REMARK 470 ASP T 225 CG OD1 OD2
REMARK 470 ASP T 226 CG OD1 OD2
REMARK 470 ASP T 227 CG OD1 OD2
REMARK 470 GLU T 234 CG CD OE1 OE2
REMARK 470 LEU T 236 CG CD1 CD2
REMARK 470 SER U 15 OG
REMARK 470 GLU U 31 CG CD OE1 OE2
REMARK 470 LYS U 42 CG CD CE NZ
REMARK 470 ASP U 43 CG OD1 OD2
REMARK 470 LYS U 56 CG CD CE NZ
REMARK 470 GLU U 60 CG CD OE1 OE2
REMARK 470 SER U 62 OG
REMARK 470 ASN U 63 CG OD1 ND2
REMARK 470 LYS U 64 CG CD CE NZ
REMARK 470 ASP U 89 CG OD1 OD2
REMARK 470 GLU U 94 CG CD OE1 OE2
REMARK 470 SER U 141 OG
REMARK 470 ASN U 143 CG OD1 ND2
REMARK 470 ASP U 144 CG OD1 OD2
REMARK 470 ASP U 152 CG OD1 OD2
REMARK 470 CYS U 163 SG
REMARK 470 GLU U 177 CG CD OE1 OE2
REMARK 470 GLU U 183 CG CD OE1 OE2
REMARK 470 ASP U 188 CG OD1 OD2
REMARK 470 LYS U 191 CG CD CE NZ
REMARK 470 GLU U 203 CG CD OE1 OE2
REMARK 470 VAL U 204 CG1 CG2
REMARK 470 LYS U 205 CG CD CE NZ
REMARK 470 LYS U 207 CG CD CE NZ
REMARK 470 GLU U 210 CG CD OE1 OE2
REMARK 470 GLU U 212 CG CD OE1 OE2
REMARK 470 SER U 214 OG
REMARK 470 GLU U 218 CG CD OE1 OE2
REMARK 470 ARG U 223 CG CD NE CZ NH1 NH2
REMARK 470 ASP U 230 CG OD1 OD2
REMARK 470 GLU U 233 CG CD OE1 OE2
REMARK 470 GLU U 234 CG CD OE1 OE2
REMARK 470 GLU U 241 CG CD OE1 OE2
REMARK 470 SER U 242 OG
REMARK 470 LYS U 244 CG CD CE NZ
REMARK 470 ASP V 9 CG OD1 OD2
REMARK 470 ASP V 32 CG OD1 OD2
REMARK 470 THR V 35 OG1 CG2
REMARK 470 ASP V 39 CG OD1 OD2
REMARK 470 ASN V 71 CG OD1 ND2
REMARK 470 GLU V 72 CG CD OE1 OE2
REMARK 470 SER V 130 OG
REMARK 470 ASP V 140 CG OD1 OD2
REMARK 470 GLU V 145 CG CD OE1 OE2
REMARK 470 GLU V 150 CG CD OE1 OE2
REMARK 470 SER V 182 OG
REMARK 470 GLU V 185 CG CD OE1 OE2
REMARK 470 ASP V 192 CG OD1 OD2
REMARK 470 GLN V 193 CG CD OE1 NE2
REMARK 470 VAL V 199 CG1 CG2
REMARK 470 THR V 201 OG1 CG2
REMARK 470 LEU V 202 CG CD1 CD2
REMARK 470 GLU W 22 CG CD OE1 OE2
REMARK 470 ASP W 28 CG OD1 OD2
REMARK 470 CYS W 31 SG
REMARK 470 MET W 54 CG SD CE
REMARK 470 GLU W 64 CG CD OE1 OE2
REMARK 470 ASP W 120 CG OD1 OD2
REMARK 470 ASP W 145 CG OD1 OD2
REMARK 470 GLU W 147 CG CD OE1 OE2
REMARK 470 GLU W 149 CG CD OE1 OE2
REMARK 470 GLU W 150 CG CD OE1 OE2
REMARK 470 ASN W 153 CG OD1 ND2
REMARK 470 GLU W 157 CG CD OE1 OE2
REMARK 470 LYS W 180 CG CD CE NZ
REMARK 470 ASN W 181 CG OD1 ND2
REMARK 470 ASP W 184 CG OD1 OD2
REMARK 470 ASN W 193 CG OD1 ND2
REMARK 470 LEU W 199 CG CD1 CD2
REMARK 470 ARG W 201 CG CD NE CZ NH1 NH2
REMARK 470 ARG W 203 CG CD NE CZ NH1 NH2
REMARK 470 CYS W 204 SG
REMARK 470 GLU W 205 CG CD OE1 OE2
REMARK 470 LYS W 206 CG CD CE NZ
REMARK 470 THR W 208 OG1 CG2
REMARK 470 GLU W 220 CG CD OE1 OE2
REMARK 470 SER X 1 OG
REMARK 470 LYS X 16 CG CD CE NZ
REMARK 470 GLN X 30 CG CD OE1 NE2
REMARK 470 ASP X 37 CG OD1 OD2
REMARK 470 ASP X 46 CG OD1 OD2
REMARK 470 GLU X 74 CG CD OE1 OE2
REMARK 470 GLU X 77 CG CD OE1 OE2
REMARK 470 GLU X 96 CG CD OE1 OE2
REMARK 470 ASP X 124 CG OD1 OD2
REMARK 470 ASP X 133 CG OD1 OD2
REMARK 470 ASP X 134 CG OD1 OD2
REMARK 470 THR X 140 OG1 CG2
REMARK 470 CYS X 149 SG
REMARK 470 GLU X 154 CG CD OE1 OE2
REMARK 470 ASP X 158 CG OD1 OD2
REMARK 470 ASP X 160 CG OD1 OD2
REMARK 470 GLU X 190 CG CD OE1 OE2
REMARK 470 LYS X 191 CG CD CE NZ
REMARK 470 MET Y 1 CG SD CE
REMARK 470 GLU Y 2 CG CD OE1 OE2
REMARK 470 SER Y 23 OG
REMARK 470 ASN Y 24 CG OD1 ND2
REMARK 470 ILE Y 25 CG1 CG2 CD1
REMARK 470 VAL Y 26 CG1 CG2
REMARK 470 ASP Y 30 CG OD1 OD2
REMARK 470 ASP Y 33 CG OD1 OD2
REMARK 470 GLU Y 40 CG CD OE1 OE2
REMARK 470 GLU Y 49 CG CD OE1 OE2
REMARK 470 GLU Y 58 CG CD OE1 OE2
REMARK 470 GLU Y 74 CG CD OE1 OE2
REMARK 470 ARG Y 95 CG CD NE CZ NH1 NH2
REMARK 470 GLU Y 109 CG CD OE1 OE2
REMARK 470 SER Y 152 OG
REMARK 470 ARG Y 155 CG CD NE CZ NH1 NH2
REMARK 470 LYS Y 169 CG CD CE NZ
REMARK 470 ASP Y 190 CG OD1 OD2
REMARK 470 ASP Y 192 CG OD1 OD2
REMARK 470 SER Z 28 OG
REMARK 470 LYS Z 71 CG CD CE NZ
REMARK 470 GLU Z 72 CG CD OE1 OE2
REMARK 470 LYS Z 81 CG CD CE NZ
REMARK 470 SER Z 96 OG
REMARK 470 ASP Z 105 CG OD1 OD2
REMARK 470 LYS Z 106 CG CD CE NZ
REMARK 470 ASP Z 115 CG OD1 OD2
REMARK 470 GLU Z 117 CG CD OE1 OE2
REMARK 470 SER Z 144 OG
REMARK 470 ASP Z 146 CG OD1 OD2
REMARK 470 GLU Z 148 CG CD OE1 OE2
REMARK 470 GLU Z 150 CG CD OE1 OE2
REMARK 470 GLU Z 181 CG CD OE1 OE2
REMARK 470 ASP Z 190 CG OD1 OD2
REMARK 470 ASP Z 194 CG OD1 OD2
REMARK 470 GLU Z 197 CG CD OE1 OE2
REMARK 470 SER Z 200 OG
REMARK 470 GLU a 18 CG CD OE1 OE2
REMARK 470 ASP a 19 CG OD1 OD2
REMARK 470 GLU a 31 CG CD OE1 OE2
REMARK 470 ASP a 39 CG OD1 OD2
REMARK 470 ASP a 48 CG OD1 OD2
REMARK 470 GLU a 69 CG CD OE1 OE2
REMARK 470 GLU a 115 CG CD OE1 OE2
REMARK 470 GLU a 116 CG CD OE1 OE2
REMARK 470 ASP a 125 CG OD1 OD2
REMARK 470 ASP a 133 CG OD1 OD2
REMARK 470 SER a 140 OG
REMARK 470 ASP a 150 CG OD1 OD2
REMARK 470 ASN a 160 CG OD1 ND2
REMARK 470 VAL a 161 CG1 CG2
REMARK 470 GLU a 162 CG CD OE1 OE2
REMARK 470 GLU a 184 CG CD OE1 OE2
REMARK 470 ASP a 191 CG OD1 OD2
REMARK 470 SER a 209 OG
REMARK 470 ASP a 213 CG OD1 OD2
REMARK 470 THR b 1 OG1 CG2
REMARK 470 GLN b 2 CG CD OE1 NE2
REMARK 470 ASN b 3 CG OD1 ND2
REMARK 470 GLU b 17 CG CD OE1 OE2
REMARK 470 SER b 40 OG
REMARK 470 GLU b 74 CG CD OE1 OE2
REMARK 470 GLU b 75 CG CD OE1 OE2
REMARK 470 SER b 82 OG
REMARK 470 LYS b 102 CG CD CE NZ
REMARK 470 ASP b 117 CG OD1 OD2
REMARK 470 ASP b 126 CG OD1 OD2
REMARK 470 GLU b 133 CG CD OE1 OE2
REMARK 470 GLU b 152 CG CD OE1 OE2
REMARK 470 GLU b 155 CG CD OE1 OE2
REMARK 470 ASP b 167 CG OD1 OD2
REMARK 470 GLU b 194 CG CD OE1 OE2
REMARK 470 LYS b 195 CG CD CE NZ
REMARK 470 GLU b 198 CG CD OE1 OE2
REMARK 470 SER b 204 OG
REMARK 470 THR b 205 OG1 CG2
REMARK 470 GLU b 206 CG CD OE1 OE2
REMARK 470 THR b 207 OG1 CG2
REMARK 470 ASN b 208 CG OD1 ND2
REMARK 470 TRP b 209 CG CD1 CD2 NE1 CE2 CE3 CZ2
REMARK 470 TRP b 209 CZ3 CH2
REMARK 470 ASP b 210 CG OD1 OD2
REMARK 470 ILE b 211 CG1 CG2 CD1
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES
REMARK 500
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)
REMARK 500
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996
REMARK 500
REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3
REMARK 500 LEU A 179 CA - CB - CG ANGL. DEV. = 15.7 DEGREES
REMARK 500 LEU A 179 CB - CG - CD2 ANGL. DEV. = -10.8 DEGREES
REMARK 500 LEU B 133 CB - CG - CD1 ANGL. DEV. = -11.4 DEGREES
REMARK 500 LEU O 179 CA - CB - CG ANGL. DEV. = 15.7 DEGREES
REMARK 500 LEU O 179 CB - CG - CD2 ANGL. DEV. = -10.8 DEGREES
REMARK 500 LEU P 133 CB - CG - CD1 ANGL. DEV. = -11.4 DEGREES
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: TORSION ANGLES
REMARK 500
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)
REMARK 500
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400
REMARK 500
REMARK 500 M RES CSSEQI PSI PHI
REMARK 500 LYS A 171 31.14 -90.35
REMARK 500 LYS A 184 -149.44 -75.03
REMARK 500 LYS A 185 152.81 -44.64
REMARK 500 GLN A 193 35.03 -94.74
REMARK 500 ASP A 209 70.56 55.52
REMARK 500 LYS B 49 71.45 -101.13
REMARK 500 THR B 68 -167.62 -113.36
REMARK 500 ASN B 213 -169.67 -115.67
REMARK 500 PHE C 61 -19.43 69.75
REMARK 500 SER C 62 -178.46 -178.18
REMARK 500 ILE C 65 -64.99 -108.30
REMARK 500 TYR C 66 72.98 59.51
REMARK 500 CYS C 74 -169.92 -117.30
REMARK 500 ALA C 208 -4.10 68.20
REMARK 500 ALA D 51 -2.69 66.25
REMARK 500 LYS D 52 16.67 58.49
REMARK 500 LYS D 204 58.47 -97.01
REMARK 500 ARG D 213 -163.74 -76.40
REMARK 500 GLN D 215 68.08 62.39
REMARK 500 SER D 216 -164.19 -79.28
REMARK 500 ASN E 13 75.18 -100.11
REMARK 500 LEU E 21 76.83 59.80
REMARK 500 GLN E 122 58.47 -95.96
REMARK 500 ASP E 147 -168.05 -116.64
REMARK 500 ASN E 211 -169.59 -125.58
REMARK 500 SER F 40 -168.61 -103.75
REMARK 500 ALA F 151 8.11 -64.72
REMARK 500 ASP F 218 34.44 -97.10
REMARK 500 ALA G 164 53.60 -140.47
REMARK 500 ALA G 168 58.37 -91.48
REMARK 500 LYS G 178 48.98 -96.62
REMARK 500 ILE I 37 -51.05 -122.87
REMARK 500 LEU I 100 127.81 -39.60
REMARK 500 ASP I 104 -168.42 -104.21
REMARK 500 SER I 171 -20.70 79.68
REMARK 500 LEU I 212 -61.49 -100.95
REMARK 500 GLN J 32 124.55 -170.89
REMARK 500 MET J 44 31.13 -88.77
REMARK 500 LEU J 48 112.57 -165.61
REMARK 500 LYS J 97 79.74 -113.38
REMARK 500 ASP J 134 -67.14 -97.92
REMARK 500 CYS J 141 57.09 -97.96
REMARK 500 MET J 203 33.13 -95.33
REMARK 500 ASP K 11 31.22 -142.23
REMARK 500 SER K 23 -165.32 -118.85
REMARK 500 ILE K 25 -39.06 -26.64
REMARK 500 SER K 39 -169.90 -124.99
REMARK 500 HIS K 99 46.34 -107.25
REMARK 500 LEU K 121 41.34 -94.94
REMARK 500 ASP K 184 -168.27 -71.37
REMARK 500
REMARK 500 THIS ENTRY HAS 130 RAMACHANDRAN OUTLIERS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS
REMARK 500
REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH
REMARK 500 CIS AND TRANS CONFORMATION. CIS BONDS, IF ANY, ARE LISTED
REMARK 500 ON CISPEP RECORDS. TRANS IS DEFINED AS 180 +/- 30 AND
REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES.
REMARK 500 MODEL OMEGA
REMARK 500 LYS A 185 LYS A 186 -127.85
REMARK 500 LYS A 186 PHE A 187 140.76
REMARK 500 ASP D 214 GLN D 215 -132.73
REMARK 500 ALA F 58 HIS F 59 -139.56
REMARK 500 GLN F 60 LYS F 61 141.69
REMARK 500 ASN K 24 ILE K 25 -132.00
REMARK 500 LYS O 185 LYS O 186 -127.90
REMARK 500 LYS O 186 PHE O 187 140.74
REMARK 500 ASP R 214 GLN R 215 -132.77
REMARK 500 ALA T 58 HIS T 59 -139.61
REMARK 500 GLN T 60 LYS T 61 141.71
REMARK 500 ASN Y 24 ILE Y 25 -132.02
REMARK 500
REMARK 500 REMARK: NULL
REMARK 900
REMARK 900 RELATED ENTRIES
REMARK 900 RELATED ID: EMD-4877 RELATED DB: EMDB
REMARK 900 HUMAN 20S PROTEASOME
DBREF 6RGQ A 1 246 UNP P60900 PSA6_HUMAN 1 246
DBREF 6RGQ B 0 233 UNP P25787 PSA2_HUMAN 1 234
DBREF 6RGQ C 1 261 UNP P25789 PSA4_HUMAN 1 261
DBREF 6RGQ D 1 248 UNP O14818 PSA7_HUMAN 1 248
DBREF 6RGQ E 1 241 UNP P28066 PSA5_HUMAN 1 241
DBREF 6RGQ F 1 263 UNP P25786 PSA1_HUMAN 1 263
DBREF 6RGQ G 0 254 UNP P25788 PSA3_HUMAN 1 255
DBREF 6RGQ H 1 205 UNP P28072 PSB6_HUMAN 35 239
DBREF 6RGQ I 1 234 UNP Q99436 PSB7_HUMAN 44 277
DBREF 6RGQ J 0 204 UNP P49720 PSB3_HUMAN 1 205
DBREF 6RGQ K 1 201 UNP P49721 PSB2_HUMAN 1 201
DBREF 6RGQ L 1 204 UNP P28074 PSB5_HUMAN 60 263
DBREF 6RGQ M 1 213 UNP P20618 PSB1_HUMAN 29 241
DBREF 6RGQ N 1 219 UNP P28070 PSB4_HUMAN 46 264
DBREF 6RGQ O 1 246 UNP P60900 PSA6_HUMAN 1 246
DBREF 6RGQ P 0 233 UNP P25787 PSA2_HUMAN 1 234
DBREF 6RGQ Q 1 261 UNP P25789 PSA4_HUMAN 1 261
DBREF 6RGQ R 1 248 UNP O14818 PSA7_HUMAN 1 248
DBREF 6RGQ S 1 241 UNP P28066 PSA5_HUMAN 1 241
DBREF 6RGQ T 1 263 UNP P25786 PSA1_HUMAN 1 263
DBREF 6RGQ U 0 254 UNP P25788 PSA3_HUMAN 1 255
DBREF 6RGQ V 1 205 UNP P28072 PSB6_HUMAN 35 239
DBREF 6RGQ W 1 234 UNP Q99436 PSB7_HUMAN 44 277
DBREF 6RGQ X 0 204 UNP P49720 PSB3_HUMAN 1 205
DBREF 6RGQ Y 1 201 UNP P49721 PSB2_HUMAN 1 201
DBREF 6RGQ Z 1 204 UNP P28074 PSB5_HUMAN 60 263
DBREF 6RGQ a 1 213 UNP P20618 PSB1_HUMAN 29 241
DBREF 6RGQ b 1 219 UNP P28070 PSB4_HUMAN 46 264
SEQRES 1 A 246 MET SER ARG GLY SER SER ALA GLY PHE ASP ARG HIS ILE
SEQRES 2 A 246 THR ILE PHE SER PRO GLU GLY ARG LEU TYR GLN VAL GLU
SEQRES 3 A 246 TYR ALA PHE LYS ALA ILE ASN GLN GLY GLY LEU THR SER
SEQRES 4 A 246 VAL ALA VAL ARG GLY LYS ASP CYS ALA VAL ILE VAL THR
SEQRES 5 A 246 GLN LYS LYS VAL PRO ASP LYS LEU LEU ASP SER SER THR
SEQRES 6 A 246 VAL THR HIS LEU PHE LYS ILE THR GLU ASN ILE GLY CYS
SEQRES 7 A 246 VAL MET THR GLY MET THR ALA ASP SER ARG SER GLN VAL
SEQRES 8 A 246 GLN ARG ALA ARG TYR GLU ALA ALA ASN TRP LYS TYR LYS
SEQRES 9 A 246 TYR GLY TYR GLU ILE PRO VAL ASP MET LEU CYS LYS ARG
SEQRES 10 A 246 ILE ALA ASP ILE SER GLN VAL TYR THR GLN ASN ALA GLU
SEQRES 11 A 246 MET ARG PRO LEU GLY CYS CYS MET ILE LEU ILE GLY ILE
SEQRES 12 A 246 ASP GLU GLU GLN GLY PRO GLN VAL TYR LYS CYS ASP PRO
SEQRES 13 A 246 ALA GLY TYR TYR CYS GLY PHE LYS ALA THR ALA ALA GLY
SEQRES 14 A 246 VAL LYS GLN THR GLU SER THR SER PHE LEU GLU LYS LYS
SEQRES 15 A 246 VAL LYS LYS LYS PHE ASP TRP THR PHE GLU GLN THR VAL
SEQRES 16 A 246 GLU THR ALA ILE THR CYS LEU SER THR VAL LEU SER ILE
SEQRES 17 A 246 ASP PHE LYS PRO SER GLU ILE GLU VAL GLY VAL VAL THR
SEQRES 18 A 246 VAL GLU ASN PRO LYS PHE ARG ILE LEU THR GLU ALA GLU
SEQRES 19 A 246 ILE ASP ALA HIS LEU VAL ALA LEU ALA GLU ARG ASP
SEQRES 1 B 234 MET ALA GLU ARG GLY TYR SER PHE SER LEU THR THR PHE
SEQRES 2 B 234 SER PRO SER GLY LYS LEU VAL GLN ILE GLU TYR ALA LEU
SEQRES 3 B 234 ALA ALA VAL ALA GLY GLY ALA PRO SER VAL GLY ILE LYS
SEQRES 4 B 234 ALA ALA ASN GLY VAL VAL LEU ALA THR GLU LYS LYS GLN
SEQRES 5 B 234 LYS SER ILE LEU TYR ASP GLU ARG SER VAL HIS LYS VAL
SEQRES 6 B 234 GLU PRO ILE THR LYS HIS ILE GLY LEU VAL TYR SER GLY
SEQRES 7 B 234 MET GLY PRO ASP TYR ARG VAL LEU VAL HIS ARG ALA ARG
SEQRES 8 B 234 LYS LEU ALA GLN GLN TYR TYR LEU VAL TYR GLN GLU PRO
SEQRES 9 B 234 ILE PRO THR ALA GLN LEU VAL GLN ARG VAL ALA SER VAL
SEQRES 10 B 234 MET GLN GLU TYR THR GLN SER GLY GLY VAL ARG PRO PHE
SEQRES 11 B 234 GLY VAL SER LEU LEU ILE CYS GLY TRP ASN GLU GLY ARG
SEQRES 12 B 234 PRO TYR LEU PHE GLN SER ASP PRO SER GLY ALA TYR PHE
SEQRES 13 B 234 ALA TRP LYS ALA THR ALA MET GLY LYS ASN TYR VAL ASN
SEQRES 14 B 234 GLY LYS THR PHE LEU GLU LYS ARG TYR ASN GLU ASP LEU
SEQRES 15 B 234 GLU LEU GLU ASP ALA ILE HIS THR ALA ILE LEU THR LEU
SEQRES 16 B 234 LYS GLU SER PHE GLU GLY GLN MET THR GLU ASP ASN ILE
SEQRES 17 B 234 GLU VAL GLY ILE CYS ASN GLU ALA GLY PHE ARG ARG LEU
SEQRES 18 B 234 THR PRO THR GLU VAL LYS ASP TYR LEU ALA ALA ILE ALA
SEQRES 1 C 261 MET SER ARG ARG TYR ASP SER ARG THR THR ILE PHE SER
SEQRES 2 C 261 PRO GLU GLY ARG LEU TYR GLN VAL GLU TYR ALA MET GLU
SEQRES 3 C 261 ALA ILE GLY HIS ALA GLY THR CYS LEU GLY ILE LEU ALA
SEQRES 4 C 261 ASN ASP GLY VAL LEU LEU ALA ALA GLU ARG ARG ASN ILE
SEQRES 5 C 261 HIS LYS LEU LEU ASP GLU VAL PHE PHE SER GLU LYS ILE
SEQRES 6 C 261 TYR LYS LEU ASN GLU ASP MET ALA CYS SER VAL ALA GLY
SEQRES 7 C 261 ILE THR SER ASP ALA ASN VAL LEU THR ASN GLU LEU ARG
SEQRES 8 C 261 LEU ILE ALA GLN ARG TYR LEU LEU GLN TYR GLN GLU PRO
SEQRES 9 C 261 ILE PRO CYS GLU GLN LEU VAL THR ALA LEU CYS ASP ILE
SEQRES 10 C 261 LYS GLN ALA TYR THR GLN PHE GLY GLY LYS ARG PRO PHE
SEQRES 11 C 261 GLY VAL SER LEU LEU TYR ILE GLY TRP ASP LYS HIS TYR
SEQRES 12 C 261 GLY PHE GLN LEU TYR GLN SER ASP PRO SER GLY ASN TYR
SEQRES 13 C 261 GLY GLY TRP LYS ALA THR CYS ILE GLY ASN ASN SER ALA
SEQRES 14 C 261 ALA ALA VAL SER MET LEU LYS GLN ASP TYR LYS GLU GLY
SEQRES 15 C 261 GLU MET THR LEU LYS SER ALA LEU ALA LEU ALA ILE LYS
SEQRES 16 C 261 VAL LEU ASN LYS THR MET ASP VAL SER LYS LEU SER ALA
SEQRES 17 C 261 GLU LYS VAL GLU ILE ALA THR LEU THR ARG GLU ASN GLY
SEQRES 18 C 261 LYS THR VAL ILE ARG VAL LEU LYS GLN LYS GLU VAL GLU
SEQRES 19 C 261 GLN LEU ILE LYS LYS HIS GLU GLU GLU GLU ALA LYS ALA
SEQRES 20 C 261 GLU ARG GLU LYS LYS GLU LYS GLU GLN LYS GLU LYS ASP
SEQRES 21 C 261 LYS
SEQRES 1 D 248 MET SER TYR ASP ARG ALA ILE THR VAL PHE SER PRO ASP
SEQRES 2 D 248 GLY HIS LEU PHE GLN VAL GLU TYR ALA GLN GLU ALA VAL
SEQRES 3 D 248 LYS LYS GLY SER THR ALA VAL GLY VAL ARG GLY ARG ASP
SEQRES 4 D 248 ILE VAL VAL LEU GLY VAL GLU LYS LYS SER VAL ALA LYS
SEQRES 5 D 248 LEU GLN ASP GLU ARG THR VAL ARG LYS ILE CYS ALA LEU
SEQRES 6 D 248 ASP ASP ASN VAL CYS MET ALA PHE ALA GLY LEU THR ALA
SEQRES 7 D 248 ASP ALA ARG ILE VAL ILE ASN ARG ALA ARG VAL GLU CYS
SEQRES 8 D 248 GLN SER HIS ARG LEU THR VAL GLU ASP PRO VAL THR VAL
SEQRES 9 D 248 GLU TYR ILE THR ARG TYR ILE ALA SER LEU LYS GLN ARG
SEQRES 10 D 248 TYR THR GLN SER ASN GLY ARG ARG PRO PHE GLY ILE SER
SEQRES 11 D 248 ALA LEU ILE VAL GLY PHE ASP PHE ASP GLY THR PRO ARG
SEQRES 12 D 248 LEU TYR GLN THR ASP PRO SER GLY THR TYR HIS ALA TRP
SEQRES 13 D 248 LYS ALA ASN ALA ILE GLY ARG GLY ALA LYS SER VAL ARG
SEQRES 14 D 248 GLU PHE LEU GLU LYS ASN TYR THR ASP GLU ALA ILE GLU
SEQRES 15 D 248 THR ASP ASP LEU THR ILE LYS LEU VAL ILE LYS ALA LEU
SEQRES 16 D 248 LEU GLU VAL VAL GLN SER GLY GLY LYS ASN ILE GLU LEU
SEQRES 17 D 248 ALA VAL MET ARG ARG ASP GLN SER LEU LYS ILE LEU ASN
SEQRES 18 D 248 PRO GLU GLU ILE GLU LYS TYR VAL ALA GLU ILE GLU LYS
SEQRES 19 D 248 GLU LYS GLU GLU ASN GLU LYS LYS LYS GLN LYS LYS ALA
SEQRES 20 D 248 SER
SEQRES 1 E 241 MET PHE LEU THR ARG SER GLU TYR ASP ARG GLY VAL ASN
SEQRES 2 E 241 THR PHE SER PRO GLU GLY ARG LEU PHE GLN VAL GLU TYR
SEQRES 3 E 241 ALA ILE GLU ALA ILE LYS LEU GLY SER THR ALA ILE GLY
SEQRES 4 E 241 ILE GLN THR SER GLU GLY VAL CYS LEU ALA VAL GLU LYS
SEQRES 5 E 241 ARG ILE THR SER PRO LEU MET GLU PRO SER SER ILE GLU
SEQRES 6 E 241 LYS ILE VAL GLU ILE ASP ALA HIS ILE GLY CYS ALA MET
SEQRES 7 E 241 SER GLY LEU ILE ALA ASP ALA LYS THR LEU ILE ASP LYS
SEQRES 8 E 241 ALA ARG VAL GLU THR GLN ASN HIS TRP PHE THR TYR ASN
SEQRES 9 E 241 GLU THR MET THR VAL GLU SER VAL THR GLN ALA VAL SER
SEQRES 10 E 241 ASN LEU ALA LEU GLN PHE GLY GLU GLU ASP ALA ASP PRO
SEQRES 11 E 241 GLY ALA MET SER ARG PRO PHE GLY VAL ALA LEU LEU PHE
SEQRES 12 E 241 GLY GLY VAL ASP GLU LYS GLY PRO GLN LEU PHE HIS MET
SEQRES 13 E 241 ASP PRO SER GLY THR PHE VAL GLN CYS ASP ALA ARG ALA
SEQRES 14 E 241 ILE GLY SER ALA SER GLU GLY ALA GLN SER SER LEU GLN
SEQRES 15 E 241 GLU VAL TYR HIS LYS SER MET THR LEU LYS GLU ALA ILE
SEQRES 16 E 241 LYS SER SER LEU ILE ILE LEU LYS GLN VAL MET GLU GLU
SEQRES 17 E 241 LYS LEU ASN ALA THR ASN ILE GLU LEU ALA THR VAL GLN
SEQRES 18 E 241 PRO GLY GLN ASN PHE HIS MET PHE THR LYS GLU GLU LEU
SEQRES 19 E 241 GLU GLU VAL ILE LYS ASP ILE
SEQRES 1 F 263 MET PHE ARG ASN GLN TYR ASP ASN ASP VAL THR VAL TRP
SEQRES 2 F 263 SER PRO GLN GLY ARG ILE HIS GLN ILE GLU TYR ALA MET
SEQRES 3 F 263 GLU ALA VAL LYS GLN GLY SER ALA THR VAL GLY LEU LYS
SEQRES 4 F 263 SER LYS THR HIS ALA VAL LEU VAL ALA LEU LYS ARG ALA
SEQRES 5 F 263 GLN SER GLU LEU ALA ALA HIS GLN LYS LYS ILE LEU HIS
SEQRES 6 F 263 VAL ASP ASN HIS ILE GLY ILE SER ILE ALA GLY LEU THR
SEQRES 7 F 263 ALA ASP ALA ARG LEU LEU CYS ASN PHE MET ARG GLN GLU
SEQRES 8 F 263 CYS LEU ASP SER ARG PHE VAL PHE ASP ARG PRO LEU PRO
SEQRES 9 F 263 VAL SER ARG LEU VAL SER LEU ILE GLY SER LYS THR GLN
SEQRES 10 F 263 ILE PRO THR GLN ARG TYR GLY ARG ARG PRO TYR GLY VAL
SEQRES 11 F 263 GLY LEU LEU ILE ALA GLY TYR ASP ASP MET GLY PRO HIS
SEQRES 12 F 263 ILE PHE GLN THR CYS PRO SER ALA ASN TYR PHE ASP CYS
SEQRES 13 F 263 ARG ALA MET SER ILE GLY ALA ARG SER GLN SER ALA ARG
SEQRES 14 F 263 THR TYR LEU GLU ARG HIS MET SER GLU PHE MET GLU CYS
SEQRES 15 F 263 ASN LEU ASN GLU LEU VAL LYS HIS GLY LEU ARG ALA LEU
SEQRES 16 F 263 ARG GLU THR LEU PRO ALA GLU GLN ASP LEU THR THR LYS
SEQRES 17 F 263 ASN VAL SER ILE GLY ILE VAL GLY LYS ASP LEU GLU PHE
SEQRES 18 F 263 THR ILE TYR ASP ASP ASP ASP VAL SER PRO PHE LEU GLU
SEQRES 19 F 263 GLY LEU GLU GLU ARG PRO GLN ARG LYS ALA GLN PRO ALA
SEQRES 20 F 263 GLN PRO ALA ASP GLU PRO ALA GLU LYS ALA ASP GLU PRO
SEQRES 21 F 263 MET GLU HIS
SEQRES 1 G 255 MET SER SER ILE GLY THR GLY TYR ASP LEU SER ALA SER
SEQRES 2 G 255 THR PHE SER PRO ASP GLY ARG VAL PHE GLN VAL GLU TYR
SEQRES 3 G 255 ALA MET LYS ALA VAL GLU ASN SER SER THR ALA ILE GLY
SEQRES 4 G 255 ILE ARG CYS LYS ASP GLY VAL VAL PHE GLY VAL GLU LYS
SEQRES 5 G 255 LEU VAL LEU SER LYS LEU TYR GLU GLU GLY SER ASN LYS
SEQRES 6 G 255 ARG LEU PHE ASN VAL ASP ARG HIS VAL GLY MET ALA VAL
SEQRES 7 G 255 ALA GLY LEU LEU ALA ASP ALA ARG SER LEU ALA ASP ILE
SEQRES 8 G 255 ALA ARG GLU GLU ALA SER ASN PHE ARG SER ASN PHE GLY
SEQRES 9 G 255 TYR ASN ILE PRO LEU LYS HIS LEU ALA ASP ARG VAL ALA
SEQRES 10 G 255 MET TYR VAL HIS ALA TYR THR LEU TYR SER ALA VAL ARG
SEQRES 11 G 255 PRO PHE GLY CYS SER PHE MET LEU GLY SER TYR SER VAL
SEQRES 12 G 255 ASN ASP GLY ALA GLN LEU TYR MET ILE ASP PRO SER GLY
SEQRES 13 G 255 VAL SER TYR GLY TYR TRP GLY CYS ALA ILE GLY LYS ALA
SEQRES 14 G 255 ARG GLN ALA ALA LYS THR GLU ILE GLU LYS LEU GLN MET
SEQRES 15 G 255 LYS GLU MET THR CYS ARG ASP ILE VAL LYS GLU VAL ALA
SEQRES 16 G 255 LYS ILE ILE TYR ILE VAL HIS ASP GLU VAL LYS ASP LYS
SEQRES 17 G 255 ALA PHE GLU LEU GLU LEU SER TRP VAL GLY GLU LEU THR
SEQRES 18 G 255 ASN GLY ARG HIS GLU ILE VAL PRO LYS ASP ILE ARG GLU
SEQRES 19 G 255 GLU ALA GLU LYS TYR ALA LYS GLU SER LEU LYS GLU GLU
SEQRES 20 G 255 ASP GLU SER ASP ASP ASP ASN MET
SEQRES 1 H 205 THR THR ILE MET ALA VAL GLN PHE ASP GLY GLY VAL VAL
SEQRES 2 H 205 LEU GLY ALA ASP SER ARG THR THR THR GLY SER TYR ILE
SEQRES 3 H 205 ALA ASN ARG VAL THR ASP LYS LEU THR PRO ILE HIS ASP
SEQRES 4 H 205 ARG ILE PHE CYS CYS ARG SER GLY SER ALA ALA ASP THR
SEQRES 5 H 205 GLN ALA VAL ALA ASP ALA VAL THR TYR GLN LEU GLY PHE
SEQRES 6 H 205 HIS SER ILE GLU LEU ASN GLU PRO PRO LEU VAL HIS THR
SEQRES 7 H 205 ALA ALA SER LEU PHE LYS GLU MET CYS TYR ARG TYR ARG
SEQRES 8 H 205 GLU ASP LEU MET ALA GLY ILE ILE ILE ALA GLY TRP ASP
SEQRES 9 H 205 PRO GLN GLU GLY GLY GLN VAL TYR SER VAL PRO MET GLY
SEQRES 10 H 205 GLY MET MET VAL ARG GLN SER PHE ALA ILE GLY GLY SER
SEQRES 11 H 205 GLY SER SER TYR ILE TYR GLY TYR VAL ASP ALA THR TYR
SEQRES 12 H 205 ARG GLU GLY MET THR LYS GLU GLU CYS LEU GLN PHE THR
SEQRES 13 H 205 ALA ASN ALA LEU ALA LEU ALA MET GLU ARG ASP GLY SER
SEQRES 14 H 205 SER GLY GLY VAL ILE ARG LEU ALA ALA ILE ALA GLU SER
SEQRES 15 H 205 GLY VAL GLU ARG GLN VAL LEU LEU GLY ASP GLN ILE PRO
SEQRES 16 H 205 LYS PHE ALA VAL ALA THR LEU PRO PRO ALA
SEQRES 1 I 234 THR THR ILE ALA GLY VAL VAL TYR LYS ASP GLY ILE VAL
SEQRES 2 I 234 LEU GLY ALA ASP THR ARG ALA THR GLU GLY MET VAL VAL
SEQRES 3 I 234 ALA ASP LYS ASN CYS SER LYS ILE HIS PHE ILE SER PRO
SEQRES 4 I 234 ASN ILE TYR CYS CYS GLY ALA GLY THR ALA ALA ASP THR
SEQRES 5 I 234 ASP MET THR THR GLN LEU ILE SER SER ASN LEU GLU LEU
SEQRES 6 I 234 HIS SER LEU SER THR GLY ARG LEU PRO ARG VAL VAL THR
SEQRES 7 I 234 ALA ASN ARG MET LEU LYS GLN MET LEU PHE ARG TYR GLN
SEQRES 8 I 234 GLY TYR ILE GLY ALA ALA LEU VAL LEU GLY GLY VAL ASP
SEQRES 9 I 234 VAL THR GLY PRO HIS LEU TYR SER ILE TYR PRO HIS GLY
SEQRES 10 I 234 SER THR ASP LYS LEU PRO TYR VAL THR MET GLY SER GLY
SEQRES 11 I 234 SER LEU ALA ALA MET ALA VAL PHE GLU ASP LYS PHE ARG
SEQRES 12 I 234 PRO ASP MET GLU GLU GLU GLU ALA LYS ASN LEU VAL SER
SEQRES 13 I 234 GLU ALA ILE ALA ALA GLY ILE PHE ASN ASP LEU GLY SER
SEQRES 14 I 234 GLY SER ASN ILE ASP LEU CYS VAL ILE SER LYS ASN LYS
SEQRES 15 I 234 LEU ASP PHE LEU ARG PRO TYR THR VAL PRO ASN LYS LYS
SEQRES 16 I 234 GLY THR ARG LEU GLY ARG TYR ARG CYS GLU LYS GLY THR
SEQRES 17 I 234 THR ALA VAL LEU THR GLU LYS ILE THR PRO LEU GLU ILE
SEQRES 18 I 234 GLU VAL LEU GLU GLU THR VAL GLN THR MET ASP THR SER
SEQRES 1 J 205 MET SER ILE MET SER TYR ASN GLY GLY ALA VAL MET ALA
SEQRES 2 J 205 MET LYS GLY LYS ASN CYS VAL ALA ILE ALA ALA ASP ARG
SEQRES 3 J 205 ARG PHE GLY ILE GLN ALA GLN MET VAL THR THR ASP PHE
SEQRES 4 J 205 GLN LYS ILE PHE PRO MET GLY ASP ARG LEU TYR ILE GLY
SEQRES 5 J 205 LEU ALA GLY LEU ALA THR ASP VAL GLN THR VAL ALA GLN
SEQRES 6 J 205 ARG LEU LYS PHE ARG LEU ASN LEU TYR GLU LEU LYS GLU
SEQRES 7 J 205 GLY ARG GLN ILE LYS PRO TYR THR LEU MET SER MET VAL
SEQRES 8 J 205 ALA ASN LEU LEU TYR GLU LYS ARG PHE GLY PRO TYR TYR
SEQRES 9 J 205 THR GLU PRO VAL ILE ALA GLY LEU ASP PRO LYS THR PHE
SEQRES 10 J 205 LYS PRO PHE ILE CYS SER LEU ASP LEU ILE GLY CYS PRO
SEQRES 11 J 205 MET VAL THR ASP ASP PHE VAL VAL SER GLY THR CYS ALA
SEQRES 12 J 205 GLU GLN MET TYR GLY MET CYS GLU SER LEU TRP GLU PRO
SEQRES 13 J 205 ASN MET ASP PRO ASP HIS LEU PHE GLU THR ILE SER GLN
SEQRES 14 J 205 ALA MET LEU ASN ALA VAL ASP ARG ASP ALA VAL SER GLY
SEQRES 15 J 205 MET GLY VAL ILE VAL HIS ILE ILE GLU LYS ASP LYS ILE
SEQRES 16 J 205 THR THR ARG THR LEU LYS ALA ARG MET ASP
SEQRES 1 K 201 MET GLU TYR LEU ILE GLY ILE GLN GLY PRO ASP TYR VAL
SEQRES 2 K 201 LEU VAL ALA SER ASP ARG VAL ALA ALA SER ASN ILE VAL
SEQRES 3 K 201 GLN MET LYS ASP ASP HIS ASP LYS MET PHE LYS MET SER
SEQRES 4 K 201 GLU LYS ILE LEU LEU LEU CYS VAL GLY GLU ALA GLY ASP
SEQRES 5 K 201 THR VAL GLN PHE ALA GLU TYR ILE GLN LYS ASN VAL GLN
SEQRES 6 K 201 LEU TYR LYS MET ARG ASN GLY TYR GLU LEU SER PRO THR
SEQRES 7 K 201 ALA ALA ALA ASN PHE THR ARG ARG ASN LEU ALA ASP CYS
SEQRES 8 K 201 LEU ARG SER ARG THR PRO TYR HIS VAL ASN LEU LEU LEU
SEQRES 9 K 201 ALA GLY TYR ASP GLU HIS GLU GLY PRO ALA LEU TYR TYR
SEQRES 10 K 201 MET ASP TYR LEU ALA ALA LEU ALA LYS ALA PRO PHE ALA
SEQRES 11 K 201 ALA HIS GLY TYR GLY ALA PHE LEU THR LEU SER ILE LEU
SEQRES 12 K 201 ASP ARG TYR TYR THR PRO THR ILE SER ARG GLU ARG ALA
SEQRES 13 K 201 VAL GLU LEU LEU ARG LYS CYS LEU GLU GLU LEU GLN LYS
SEQRES 14 K 201 ARG PHE ILE LEU ASN LEU PRO THR PHE SER VAL ARG ILE
SEQRES 15 K 201 ILE ASP LYS ASN GLY ILE HIS ASP LEU ASP ASN ILE SER
SEQRES 16 K 201 PHE PRO LYS GLN GLY SER
SEQRES 1 L 204 THR THR THR LEU ALA PHE LYS PHE ARG HIS GLY VAL ILE
SEQRES 2 L 204 VAL ALA ALA ASP SER ARG ALA THR ALA GLY ALA TYR ILE
SEQRES 3 L 204 ALA SER GLN THR VAL LYS LYS VAL ILE GLU ILE ASN PRO
SEQRES 4 L 204 TYR LEU LEU GLY THR MET ALA GLY GLY ALA ALA ASP CYS
SEQRES 5 L 204 SER PHE TRP GLU ARG LEU LEU ALA ARG GLN CYS ARG ILE
SEQRES 6 L 204 TYR GLU LEU ARG ASN LYS GLU ARG ILE SER VAL ALA ALA
SEQRES 7 L 204 ALA SER LYS LEU LEU ALA ASN MET VAL TYR GLN TYR LYS
SEQRES 8 L 204 GLY MET GLY LEU SER MET GLY THR MET ILE CYS GLY TRP
SEQRES 9 L 204 ASP LYS ARG GLY PRO GLY LEU TYR TYR VAL ASP SER GLU
SEQRES 10 L 204 GLY ASN ARG ILE SER GLY ALA THR PHE SER VAL GLY SER
SEQRES 11 L 204 GLY SER VAL TYR ALA TYR GLY VAL MET ASP ARG GLY TYR
SEQRES 12 L 204 SER TYR ASP LEU GLU VAL GLU GLN ALA TYR ASP LEU ALA
SEQRES 13 L 204 ARG ARG ALA ILE TYR GLN ALA THR TYR ARG ASP ALA TYR
SEQRES 14 L 204 SER GLY GLY ALA VAL ASN LEU TYR HIS VAL ARG GLU ASP
SEQRES 15 L 204 GLY TRP ILE ARG VAL SER SER ASP ASN VAL ALA ASP LEU
SEQRES 16 L 204 HIS GLU LYS TYR SER GLY SER THR PRO
SEQRES 1 M 213 ARG PHE SER PRO TYR VAL PHE ASN GLY GLY THR ILE LEU
SEQRES 2 M 213 ALA ILE ALA GLY GLU ASP PHE ALA ILE VAL ALA SER ASP
SEQRES 3 M 213 THR ARG LEU SER GLU GLY PHE SER ILE HIS THR ARG ASP
SEQRES 4 M 213 SER PRO LYS CYS TYR LYS LEU THR ASP LYS THR VAL ILE
SEQRES 5 M 213 GLY CYS SER GLY PHE HIS GLY ASP CYS LEU THR LEU THR
SEQRES 6 M 213 LYS ILE ILE GLU ALA ARG LEU LYS MET TYR LYS HIS SER
SEQRES 7 M 213 ASN ASN LYS ALA MET THR THR GLY ALA ILE ALA ALA MET
SEQRES 8 M 213 LEU SER THR ILE LEU TYR SER ARG ARG PHE PHE PRO TYR
SEQRES 9 M 213 TYR VAL TYR ASN ILE ILE GLY GLY LEU ASP GLU GLU GLY
SEQRES 10 M 213 LYS GLY ALA VAL TYR SER PHE ASP PRO VAL GLY SER TYR
SEQRES 11 M 213 GLN ARG ASP SER PHE LYS ALA GLY GLY SER ALA SER ALA
SEQRES 12 M 213 MET LEU GLN PRO LEU LEU ASP ASN GLN VAL GLY PHE LYS
SEQRES 13 M 213 ASN MET GLN ASN VAL GLU HIS VAL PRO LEU SER LEU ASP
SEQRES 14 M 213 ARG ALA MET ARG LEU VAL LYS ASP VAL PHE ILE SER ALA
SEQRES 15 M 213 ALA GLU ARG ASP VAL TYR THR GLY ASP ALA LEU ARG ILE
SEQRES 16 M 213 CYS ILE VAL THR LYS GLU GLY ILE ARG GLU GLU THR VAL
SEQRES 17 M 213 SER LEU ARG LYS ASP
SEQRES 1 N 219 THR GLN ASN PRO MET VAL THR GLY THR SER VAL LEU GLY
SEQRES 2 N 219 VAL LYS PHE GLU GLY GLY VAL VAL ILE ALA ALA ASP MET
SEQRES 3 N 219 LEU GLY SER TYR GLY SER LEU ALA ARG PHE ARG ASN ILE
SEQRES 4 N 219 SER ARG ILE MET ARG VAL ASN ASN SER THR MET LEU GLY
SEQRES 5 N 219 ALA SER GLY ASP TYR ALA ASP PHE GLN TYR LEU LYS GLN
SEQRES 6 N 219 VAL LEU GLY GLN MET VAL ILE ASP GLU GLU LEU LEU GLY
SEQRES 7 N 219 ASP GLY HIS SER TYR SER PRO ARG ALA ILE HIS SER TRP
SEQRES 8 N 219 LEU THR ARG ALA MET TYR SER ARG ARG SER LYS MET ASN
SEQRES 9 N 219 PRO LEU TRP ASN THR MET VAL ILE GLY GLY TYR ALA ASP
SEQRES 10 N 219 GLY GLU SER PHE LEU GLY TYR VAL ASP MET LEU GLY VAL
SEQRES 11 N 219 ALA TYR GLU ALA PRO SER LEU ALA THR GLY TYR GLY ALA
SEQRES 12 N 219 TYR LEU ALA GLN PRO LEU LEU ARG GLU VAL LEU GLU LYS
SEQRES 13 N 219 GLN PRO VAL LEU SER GLN THR GLU ALA ARG ASP LEU VAL
SEQRES 14 N 219 GLU ARG CYS MET ARG VAL LEU TYR TYR ARG ASP ALA ARG
SEQRES 15 N 219 SER TYR ASN ARG PHE GLN ILE ALA THR VAL THR GLU LYS
SEQRES 16 N 219 GLY VAL GLU ILE GLU GLY PRO LEU SER THR GLU THR ASN
SEQRES 17 N 219 TRP ASP ILE ALA HIS MET ILE SER GLY PHE GLU
SEQRES 1 O 246 MET SER ARG GLY SER SER ALA GLY PHE ASP ARG HIS ILE
SEQRES 2 O 246 THR ILE PHE SER PRO GLU GLY ARG LEU TYR GLN VAL GLU
SEQRES 3 O 246 TYR ALA PHE LYS ALA ILE ASN GLN GLY GLY LEU THR SER
SEQRES 4 O 246 VAL ALA VAL ARG GLY LYS ASP CYS ALA VAL ILE VAL THR
SEQRES 5 O 246 GLN LYS LYS VAL PRO ASP LYS LEU LEU ASP SER SER THR
SEQRES 6 O 246 VAL THR HIS LEU PHE LYS ILE THR GLU ASN ILE GLY CYS
SEQRES 7 O 246 VAL MET THR GLY MET THR ALA ASP SER ARG SER GLN VAL
SEQRES 8 O 246 GLN ARG ALA ARG TYR GLU ALA ALA ASN TRP LYS TYR LYS
SEQRES 9 O 246 TYR GLY TYR GLU ILE PRO VAL ASP MET LEU CYS LYS ARG
SEQRES 10 O 246 ILE ALA ASP ILE SER GLN VAL TYR THR GLN ASN ALA GLU
SEQRES 11 O 246 MET ARG PRO LEU GLY CYS CYS MET ILE LEU ILE GLY ILE
SEQRES 12 O 246 ASP GLU GLU GLN GLY PRO GLN VAL TYR LYS CYS ASP PRO
SEQRES 13 O 246 ALA GLY TYR TYR CYS GLY PHE LYS ALA THR ALA ALA GLY
SEQRES 14 O 246 VAL LYS GLN THR GLU SER THR SER PHE LEU GLU LYS LYS
SEQRES 15 O 246 VAL LYS LYS LYS PHE ASP TRP THR PHE GLU GLN THR VAL
SEQRES 16 O 246 GLU THR ALA ILE THR CYS LEU SER THR VAL LEU SER ILE
SEQRES 17 O 246 ASP PHE LYS PRO SER GLU ILE GLU VAL GLY VAL VAL THR
SEQRES 18 O 246 VAL GLU ASN PRO LYS PHE ARG ILE LEU THR GLU ALA GLU
SEQRES 19 O 246 ILE ASP ALA HIS LEU VAL ALA LEU ALA GLU ARG ASP
SEQRES 1 P 234 MET ALA GLU ARG GLY TYR SER PHE SER LEU THR THR PHE
SEQRES 2 P 234 SER PRO SER GLY LYS LEU VAL GLN ILE GLU TYR ALA LEU
SEQRES 3 P 234 ALA ALA VAL ALA GLY GLY ALA PRO SER VAL GLY ILE LYS
SEQRES 4 P 234 ALA ALA ASN GLY VAL VAL LEU ALA THR GLU LYS LYS GLN
SEQRES 5 P 234 LYS SER ILE LEU TYR ASP GLU ARG SER VAL HIS LYS VAL
SEQRES 6 P 234 GLU PRO ILE THR LYS HIS ILE GLY LEU VAL TYR SER GLY
SEQRES 7 P 234 MET GLY PRO ASP TYR ARG VAL LEU VAL HIS ARG ALA ARG
SEQRES 8 P 234 LYS LEU ALA GLN GLN TYR TYR LEU VAL TYR GLN GLU PRO
SEQRES 9 P 234 ILE PRO THR ALA GLN LEU VAL GLN ARG VAL ALA SER VAL
SEQRES 10 P 234 MET GLN GLU TYR THR GLN SER GLY GLY VAL ARG PRO PHE
SEQRES 11 P 234 GLY VAL SER LEU LEU ILE CYS GLY TRP ASN GLU GLY ARG
SEQRES 12 P 234 PRO TYR LEU PHE GLN SER ASP PRO SER GLY ALA TYR PHE
SEQRES 13 P 234 ALA TRP LYS ALA THR ALA MET GLY LYS ASN TYR VAL ASN
SEQRES 14 P 234 GLY LYS THR PHE LEU GLU LYS ARG TYR ASN GLU ASP LEU
SEQRES 15 P 234 GLU LEU GLU ASP ALA ILE HIS THR ALA ILE LEU THR LEU
SEQRES 16 P 234 LYS GLU SER PHE GLU GLY GLN MET THR GLU ASP ASN ILE
SEQRES 17 P 234 GLU VAL GLY ILE CYS ASN GLU ALA GLY PHE ARG ARG LEU
SEQRES 18 P 234 THR PRO THR GLU VAL LYS ASP TYR LEU ALA ALA ILE ALA
SEQRES 1 Q 261 MET SER ARG ARG TYR ASP SER ARG THR THR ILE PHE SER
SEQRES 2 Q 261 PRO GLU GLY ARG LEU TYR GLN VAL GLU TYR ALA MET GLU
SEQRES 3 Q 261 ALA ILE GLY HIS ALA GLY THR CYS LEU GLY ILE LEU ALA
SEQRES 4 Q 261 ASN ASP GLY VAL LEU LEU ALA ALA GLU ARG ARG ASN ILE
SEQRES 5 Q 261 HIS LYS LEU LEU ASP GLU VAL PHE PHE SER GLU LYS ILE
SEQRES 6 Q 261 TYR LYS LEU ASN GLU ASP MET ALA CYS SER VAL ALA GLY
SEQRES 7 Q 261 ILE THR SER ASP ALA ASN VAL LEU THR ASN GLU LEU ARG
SEQRES 8 Q 261 LEU ILE ALA GLN ARG TYR LEU LEU GLN TYR GLN GLU PRO
SEQRES 9 Q 261 ILE PRO CYS GLU GLN LEU VAL THR ALA LEU CYS ASP ILE
SEQRES 10 Q 261 LYS GLN ALA TYR THR GLN PHE GLY GLY LYS ARG PRO PHE
SEQRES 11 Q 261 GLY VAL SER LEU LEU TYR ILE GLY TRP ASP LYS HIS TYR
SEQRES 12 Q 261 GLY PHE GLN LEU TYR GLN SER ASP PRO SER GLY ASN TYR
SEQRES 13 Q 261 GLY GLY TRP LYS ALA THR CYS ILE GLY ASN ASN SER ALA
SEQRES 14 Q 261 ALA ALA VAL SER MET LEU LYS GLN ASP TYR LYS GLU GLY
SEQRES 15 Q 261 GLU MET THR LEU LYS SER ALA LEU ALA LEU ALA ILE LYS
SEQRES 16 Q 261 VAL LEU ASN LYS THR MET ASP VAL SER LYS LEU SER ALA
SEQRES 17 Q 261 GLU LYS VAL GLU ILE ALA THR LEU THR ARG GLU ASN GLY
SEQRES 18 Q 261 LYS THR VAL ILE ARG VAL LEU LYS GLN LYS GLU VAL GLU
SEQRES 19 Q 261 GLN LEU ILE LYS LYS HIS GLU GLU GLU GLU ALA LYS ALA
SEQRES 20 Q 261 GLU ARG GLU LYS LYS GLU LYS GLU GLN LYS GLU LYS ASP
SEQRES 21 Q 261 LYS
SEQRES 1 R 248 MET SER TYR ASP ARG ALA ILE THR VAL PHE SER PRO ASP
SEQRES 2 R 248 GLY HIS LEU PHE GLN VAL GLU TYR ALA GLN GLU ALA VAL
SEQRES 3 R 248 LYS LYS GLY SER THR ALA VAL GLY VAL ARG GLY ARG ASP
SEQRES 4 R 248 ILE VAL VAL LEU GLY VAL GLU LYS LYS SER VAL ALA LYS
SEQRES 5 R 248 LEU GLN ASP GLU ARG THR VAL ARG LYS ILE CYS ALA LEU
SEQRES 6 R 248 ASP ASP ASN VAL CYS MET ALA PHE ALA GLY LEU THR ALA
SEQRES 7 R 248 ASP ALA ARG ILE VAL ILE ASN ARG ALA ARG VAL GLU CYS
SEQRES 8 R 248 GLN SER HIS ARG LEU THR VAL GLU ASP PRO VAL THR VAL
SEQRES 9 R 248 GLU TYR ILE THR ARG TYR ILE ALA SER LEU LYS GLN ARG
SEQRES 10 R 248 TYR THR GLN SER ASN GLY ARG ARG PRO PHE GLY ILE SER
SEQRES 11 R 248 ALA LEU ILE VAL GLY PHE ASP PHE ASP GLY THR PRO ARG
SEQRES 12 R 248 LEU TYR GLN THR ASP PRO SER GLY THR TYR HIS ALA TRP
SEQRES 13 R 248 LYS ALA ASN ALA ILE GLY ARG GLY ALA LYS SER VAL ARG
SEQRES 14 R 248 GLU PHE LEU GLU LYS ASN TYR THR ASP GLU ALA ILE GLU
SEQRES 15 R 248 THR ASP ASP LEU THR ILE LYS LEU VAL ILE LYS ALA LEU
SEQRES 16 R 248 LEU GLU VAL VAL GLN SER GLY GLY LYS ASN ILE GLU LEU
SEQRES 17 R 248 ALA VAL MET ARG ARG ASP GLN SER LEU LYS ILE LEU ASN
SEQRES 18 R 248 PRO GLU GLU ILE GLU LYS TYR VAL ALA GLU ILE GLU LYS
SEQRES 19 R 248 GLU LYS GLU GLU ASN GLU LYS LYS LYS GLN LYS LYS ALA
SEQRES 20 R 248 SER
SEQRES 1 S 241 MET PHE LEU THR ARG SER GLU TYR ASP ARG GLY VAL ASN
SEQRES 2 S 241 THR PHE SER PRO GLU GLY ARG LEU PHE GLN VAL GLU TYR
SEQRES 3 S 241 ALA ILE GLU ALA ILE LYS LEU GLY SER THR ALA ILE GLY
SEQRES 4 S 241 ILE GLN THR SER GLU GLY VAL CYS LEU ALA VAL GLU LYS
SEQRES 5 S 241 ARG ILE THR SER PRO LEU MET GLU PRO SER SER ILE GLU
SEQRES 6 S 241 LYS ILE VAL GLU ILE ASP ALA HIS ILE GLY CYS ALA MET
SEQRES 7 S 241 SER GLY LEU ILE ALA ASP ALA LYS THR LEU ILE ASP LYS
SEQRES 8 S 241 ALA ARG VAL GLU THR GLN ASN HIS TRP PHE THR TYR ASN
SEQRES 9 S 241 GLU THR MET THR VAL GLU SER VAL THR GLN ALA VAL SER
SEQRES 10 S 241 ASN LEU ALA LEU GLN PHE GLY GLU GLU ASP ALA ASP PRO
SEQRES 11 S 241 GLY ALA MET SER ARG PRO PHE GLY VAL ALA LEU LEU PHE
SEQRES 12 S 241 GLY GLY VAL ASP GLU LYS GLY PRO GLN LEU PHE HIS MET
SEQRES 13 S 241 ASP PRO SER GLY THR PHE VAL GLN CYS ASP ALA ARG ALA
SEQRES 14 S 241 ILE GLY SER ALA SER GLU GLY ALA GLN SER SER LEU GLN
SEQRES 15 S 241 GLU VAL TYR HIS LYS SER MET THR LEU LYS GLU ALA ILE
SEQRES 16 S 241 LYS SER SER LEU ILE ILE LEU LYS GLN VAL MET GLU GLU
SEQRES 17 S 241 LYS LEU ASN ALA THR ASN ILE GLU LEU ALA THR VAL GLN
SEQRES 18 S 241 PRO GLY GLN ASN PHE HIS MET PHE THR LYS GLU GLU LEU
SEQRES 19 S 241 GLU GLU VAL ILE LYS ASP ILE
SEQRES 1 T 263 MET PHE ARG ASN GLN TYR ASP ASN ASP VAL THR VAL TRP
SEQRES 2 T 263 SER PRO GLN GLY ARG ILE HIS GLN ILE GLU TYR ALA MET
SEQRES 3 T 263 GLU ALA VAL LYS GLN GLY SER ALA THR VAL GLY LEU LYS
SEQRES 4 T 263 SER LYS THR HIS ALA VAL LEU VAL ALA LEU LYS ARG ALA
SEQRES 5 T 263 GLN SER GLU LEU ALA ALA HIS GLN LYS LYS ILE LEU HIS
SEQRES 6 T 263 VAL ASP ASN HIS ILE GLY ILE SER ILE ALA GLY LEU THR
SEQRES 7 T 263 ALA ASP ALA ARG LEU LEU CYS ASN PHE MET ARG GLN GLU
SEQRES 8 T 263 CYS LEU ASP SER ARG PHE VAL PHE ASP ARG PRO LEU PRO
SEQRES 9 T 263 VAL SER ARG LEU VAL SER LEU ILE GLY SER LYS THR GLN
SEQRES 10 T 263 ILE PRO THR GLN ARG TYR GLY ARG ARG PRO TYR GLY VAL
SEQRES 11 T 263 GLY LEU LEU ILE ALA GLY TYR ASP ASP MET GLY PRO HIS
SEQRES 12 T 263 ILE PHE GLN THR CYS PRO SER ALA ASN TYR PHE ASP CYS
SEQRES 13 T 263 ARG ALA MET SER ILE GLY ALA ARG SER GLN SER ALA ARG
SEQRES 14 T 263 THR TYR LEU GLU ARG HIS MET SER GLU PHE MET GLU CYS
SEQRES 15 T 263 ASN LEU ASN GLU LEU VAL LYS HIS GLY LEU ARG ALA LEU
SEQRES 16 T 263 ARG GLU THR LEU PRO ALA GLU GLN ASP LEU THR THR LYS
SEQRES 17 T 263 ASN VAL SER ILE GLY ILE VAL GLY LYS ASP LEU GLU PHE
SEQRES 18 T 263 THR ILE TYR ASP ASP ASP ASP VAL SER PRO PHE LEU GLU
SEQRES 19 T 263 GLY LEU GLU GLU ARG PRO GLN ARG LYS ALA GLN PRO ALA
SEQRES 20 T 263 GLN PRO ALA ASP GLU PRO ALA GLU LYS ALA ASP GLU PRO
SEQRES 21 T 263 MET GLU HIS
SEQRES 1 U 255 MET SER SER ILE GLY THR GLY TYR ASP LEU SER ALA SER
SEQRES 2 U 255 THR PHE SER PRO ASP GLY ARG VAL PHE GLN VAL GLU TYR
SEQRES 3 U 255 ALA MET LYS ALA VAL GLU ASN SER SER THR ALA ILE GLY
SEQRES 4 U 255 ILE ARG CYS LYS ASP GLY VAL VAL PHE GLY VAL GLU LYS
SEQRES 5 U 255 LEU VAL LEU SER LYS LEU TYR GLU GLU GLY SER ASN LYS
SEQRES 6 U 255 ARG LEU PHE ASN VAL ASP ARG HIS VAL GLY MET ALA VAL
SEQRES 7 U 255 ALA GLY LEU LEU ALA ASP ALA ARG SER LEU ALA ASP ILE
SEQRES 8 U 255 ALA ARG GLU GLU ALA SER ASN PHE ARG SER ASN PHE GLY
SEQRES 9 U 255 TYR ASN ILE PRO LEU LYS HIS LEU ALA ASP ARG VAL ALA
SEQRES 10 U 255 MET TYR VAL HIS ALA TYR THR LEU TYR SER ALA VAL ARG
SEQRES 11 U 255 PRO PHE GLY CYS SER PHE MET LEU GLY SER TYR SER VAL
SEQRES 12 U 255 ASN ASP GLY ALA GLN LEU TYR MET ILE ASP PRO SER GLY
SEQRES 13 U 255 VAL SER TYR GLY TYR TRP GLY CYS ALA ILE GLY LYS ALA
SEQRES 14 U 255 ARG GLN ALA ALA LYS THR GLU ILE GLU LYS LEU GLN MET
SEQRES 15 U 255 LYS GLU MET THR CYS ARG ASP ILE VAL LYS GLU VAL ALA
SEQRES 16 U 255 LYS ILE ILE TYR ILE VAL HIS ASP GLU VAL LYS ASP LYS
SEQRES 17 U 255 ALA PHE GLU LEU GLU LEU SER TRP VAL GLY GLU LEU THR
SEQRES 18 U 255 ASN GLY ARG HIS GLU ILE VAL PRO LYS ASP ILE ARG GLU
SEQRES 19 U 255 GLU ALA GLU LYS TYR ALA LYS GLU SER LEU LYS GLU GLU
SEQRES 20 U 255 ASP GLU SER ASP ASP ASP ASN MET
SEQRES 1 V 205 THR THR ILE MET ALA VAL GLN PHE ASP GLY GLY VAL VAL
SEQRES 2 V 205 LEU GLY ALA ASP SER ARG THR THR THR GLY SER TYR ILE
SEQRES 3 V 205 ALA ASN ARG VAL THR ASP LYS LEU THR PRO ILE HIS ASP
SEQRES 4 V 205 ARG ILE PHE CYS CYS ARG SER GLY SER ALA ALA ASP THR
SEQRES 5 V 205 GLN ALA VAL ALA ASP ALA VAL THR TYR GLN LEU GLY PHE
SEQRES 6 V 205 HIS SER ILE GLU LEU ASN GLU PRO PRO LEU VAL HIS THR
SEQRES 7 V 205 ALA ALA SER LEU PHE LYS GLU MET CYS TYR ARG TYR ARG
SEQRES 8 V 205 GLU ASP LEU MET ALA GLY ILE ILE ILE ALA GLY TRP ASP
SEQRES 9 V 205 PRO GLN GLU GLY GLY GLN VAL TYR SER VAL PRO MET GLY
SEQRES 10 V 205 GLY MET MET VAL ARG GLN SER PHE ALA ILE GLY GLY SER
SEQRES 11 V 205 GLY SER SER TYR ILE TYR GLY TYR VAL ASP ALA THR TYR
SEQRES 12 V 205 ARG GLU GLY MET THR LYS GLU GLU CYS LEU GLN PHE THR
SEQRES 13 V 205 ALA ASN ALA LEU ALA LEU ALA MET GLU ARG ASP GLY SER
SEQRES 14 V 205 SER GLY GLY VAL ILE ARG LEU ALA ALA ILE ALA GLU SER
SEQRES 15 V 205 GLY VAL GLU ARG GLN VAL LEU LEU GLY ASP GLN ILE PRO
SEQRES 16 V 205 LYS PHE ALA VAL ALA THR LEU PRO PRO ALA
SEQRES 1 W 234 THR THR ILE ALA GLY VAL VAL TYR LYS ASP GLY ILE VAL
SEQRES 2 W 234 LEU GLY ALA ASP THR ARG ALA THR GLU GLY MET VAL VAL
SEQRES 3 W 234 ALA ASP LYS ASN CYS SER LYS ILE HIS PHE ILE SER PRO
SEQRES 4 W 234 ASN ILE TYR CYS CYS GLY ALA GLY THR ALA ALA ASP THR
SEQRES 5 W 234 ASP MET THR THR GLN LEU ILE SER SER ASN LEU GLU LEU
SEQRES 6 W 234 HIS SER LEU SER THR GLY ARG LEU PRO ARG VAL VAL THR
SEQRES 7 W 234 ALA ASN ARG MET LEU LYS GLN MET LEU PHE ARG TYR GLN
SEQRES 8 W 234 GLY TYR ILE GLY ALA ALA LEU VAL LEU GLY GLY VAL ASP
SEQRES 9 W 234 VAL THR GLY PRO HIS LEU TYR SER ILE TYR PRO HIS GLY
SEQRES 10 W 234 SER THR ASP LYS LEU PRO TYR VAL THR MET GLY SER GLY
SEQRES 11 W 234 SER LEU ALA ALA MET ALA VAL PHE GLU ASP LYS PHE ARG
SEQRES 12 W 234 PRO ASP MET GLU GLU GLU GLU ALA LYS ASN LEU VAL SER
SEQRES 13 W 234 GLU ALA ILE ALA ALA GLY ILE PHE ASN ASP LEU GLY SER
SEQRES 14 W 234 GLY SER ASN ILE ASP LEU CYS VAL ILE SER LYS ASN LYS
SEQRES 15 W 234 LEU ASP PHE LEU ARG PRO TYR THR VAL PRO ASN LYS LYS
SEQRES 16 W 234 GLY THR ARG LEU GLY ARG TYR ARG CYS GLU LYS GLY THR
SEQRES 17 W 234 THR ALA VAL LEU THR GLU LYS ILE THR PRO LEU GLU ILE
SEQRES 18 W 234 GLU VAL LEU GLU GLU THR VAL GLN THR MET ASP THR SER
SEQRES 1 X 205 MET SER ILE MET SER TYR ASN GLY GLY ALA VAL MET ALA
SEQRES 2 X 205 MET LYS GLY LYS ASN CYS VAL ALA ILE ALA ALA ASP ARG
SEQRES 3 X 205 ARG PHE GLY ILE GLN ALA GLN MET VAL THR THR ASP PHE
SEQRES 4 X 205 GLN LYS ILE PHE PRO MET GLY ASP ARG LEU TYR ILE GLY
SEQRES 5 X 205 LEU ALA GLY LEU ALA THR ASP VAL GLN THR VAL ALA GLN
SEQRES 6 X 205 ARG LEU LYS PHE ARG LEU ASN LEU TYR GLU LEU LYS GLU
SEQRES 7 X 205 GLY ARG GLN ILE LYS PRO TYR THR LEU MET SER MET VAL
SEQRES 8 X 205 ALA ASN LEU LEU TYR GLU LYS ARG PHE GLY PRO TYR TYR
SEQRES 9 X 205 THR GLU PRO VAL ILE ALA GLY LEU ASP PRO LYS THR PHE
SEQRES 10 X 205 LYS PRO PHE ILE CYS SER LEU ASP LEU ILE GLY CYS PRO
SEQRES 11 X 205 MET VAL THR ASP ASP PHE VAL VAL SER GLY THR CYS ALA
SEQRES 12 X 205 GLU GLN MET TYR GLY MET CYS GLU SER LEU TRP GLU PRO
SEQRES 13 X 205 ASN MET ASP PRO ASP HIS LEU PHE GLU THR ILE SER GLN
SEQRES 14 X 205 ALA MET LEU ASN ALA VAL ASP ARG ASP ALA VAL SER GLY
SEQRES 15 X 205 MET GLY VAL ILE VAL HIS ILE ILE GLU LYS ASP LYS ILE
SEQRES 16 X 205 THR THR ARG THR LEU LYS ALA ARG MET ASP
SEQRES 1 Y 201 MET GLU TYR LEU ILE GLY ILE GLN GLY PRO ASP TYR VAL
SEQRES 2 Y 201 LEU VAL ALA SER ASP ARG VAL ALA ALA SER ASN ILE VAL
SEQRES 3 Y 201 GLN MET LYS ASP ASP HIS ASP LYS MET PHE LYS MET SER
SEQRES 4 Y 201 GLU LYS ILE LEU LEU LEU CYS VAL GLY GLU ALA GLY ASP
SEQRES 5 Y 201 THR VAL GLN PHE ALA GLU TYR ILE GLN LYS ASN VAL GLN
SEQRES 6 Y 201 LEU TYR LYS MET ARG ASN GLY TYR GLU LEU SER PRO THR
SEQRES 7 Y 201 ALA ALA ALA ASN PHE THR ARG ARG ASN LEU ALA ASP CYS
SEQRES 8 Y 201 LEU ARG SER ARG THR PRO TYR HIS VAL ASN LEU LEU LEU
SEQRES 9 Y 201 ALA GLY TYR ASP GLU HIS GLU GLY PRO ALA LEU TYR TYR
SEQRES 10 Y 201 MET ASP TYR LEU ALA ALA LEU ALA LYS ALA PRO PHE ALA
SEQRES 11 Y 201 ALA HIS GLY TYR GLY ALA PHE LEU THR LEU SER ILE LEU
SEQRES 12 Y 201 ASP ARG TYR TYR THR PRO THR ILE SER ARG GLU ARG ALA
SEQRES 13 Y 201 VAL GLU LEU LEU ARG LYS CYS LEU GLU GLU LEU GLN LYS
SEQRES 14 Y 201 ARG PHE ILE LEU ASN LEU PRO THR PHE SER VAL ARG ILE
SEQRES 15 Y 201 ILE ASP LYS ASN GLY ILE HIS ASP LEU ASP ASN ILE SER
SEQRES 16 Y 201 PHE PRO LYS GLN GLY SER
SEQRES 1 Z 204 THR THR THR LEU ALA PHE LYS PHE ARG HIS GLY VAL ILE
SEQRES 2 Z 204 VAL ALA ALA ASP SER ARG ALA THR ALA GLY ALA TYR ILE
SEQRES 3 Z 204 ALA SER GLN THR VAL LYS LYS VAL ILE GLU ILE ASN PRO
SEQRES 4 Z 204 TYR LEU LEU GLY THR MET ALA GLY GLY ALA ALA ASP CYS
SEQRES 5 Z 204 SER PHE TRP GLU ARG LEU LEU ALA ARG GLN CYS ARG ILE
SEQRES 6 Z 204 TYR GLU LEU ARG ASN LYS GLU ARG ILE SER VAL ALA ALA
SEQRES 7 Z 204 ALA SER LYS LEU LEU ALA ASN MET VAL TYR GLN TYR LYS
SEQRES 8 Z 204 GLY MET GLY LEU SER MET GLY THR MET ILE CYS GLY TRP
SEQRES 9 Z 204 ASP LYS ARG GLY PRO GLY LEU TYR TYR VAL ASP SER GLU
SEQRES 10 Z 204 GLY ASN ARG ILE SER GLY ALA THR PHE SER VAL GLY SER
SEQRES 11 Z 204 GLY SER VAL TYR ALA TYR GLY VAL MET ASP ARG GLY TYR
SEQRES 12 Z 204 SER TYR ASP LEU GLU VAL GLU GLN ALA TYR ASP LEU ALA
SEQRES 13 Z 204 ARG ARG ALA ILE TYR GLN ALA THR TYR ARG ASP ALA TYR
SEQRES 14 Z 204 SER GLY GLY ALA VAL ASN LEU TYR HIS VAL ARG GLU ASP
SEQRES 15 Z 204 GLY TRP ILE ARG VAL SER SER ASP ASN VAL ALA ASP LEU
SEQRES 16 Z 204 HIS GLU LYS TYR SER GLY SER THR PRO
SEQRES 1 a 213 ARG PHE SER PRO TYR VAL PHE ASN GLY GLY THR ILE LEU
SEQRES 2 a 213 ALA ILE ALA GLY GLU ASP PHE ALA ILE VAL ALA SER ASP
SEQRES 3 a 213 THR ARG LEU SER GLU GLY PHE SER ILE HIS THR ARG ASP
SEQRES 4 a 213 SER PRO LYS CYS TYR LYS LEU THR ASP LYS THR VAL ILE
SEQRES 5 a 213 GLY CYS SER GLY PHE HIS GLY ASP CYS LEU THR LEU THR
SEQRES 6 a 213 LYS ILE ILE GLU ALA ARG LEU LYS MET TYR LYS HIS SER
SEQRES 7 a 213 ASN ASN LYS ALA MET THR THR GLY ALA ILE ALA ALA MET
SEQRES 8 a 213 LEU SER THR ILE LEU TYR SER ARG ARG PHE PHE PRO TYR
SEQRES 9 a 213 TYR VAL TYR ASN ILE ILE GLY GLY LEU ASP GLU GLU GLY
SEQRES 10 a 213 LYS GLY ALA VAL TYR SER PHE ASP PRO VAL GLY SER TYR
SEQRES 11 a 213 GLN ARG ASP SER PHE LYS ALA GLY GLY SER ALA SER ALA
SEQRES 12 a 213 MET LEU GLN PRO LEU LEU ASP ASN GLN VAL GLY PHE LYS
SEQRES 13 a 213 ASN MET GLN ASN VAL GLU HIS VAL PRO LEU SER LEU ASP
SEQRES 14 a 213 ARG ALA MET ARG LEU VAL LYS ASP VAL PHE ILE SER ALA
SEQRES 15 a 213 ALA GLU ARG ASP VAL TYR THR GLY ASP ALA LEU ARG ILE
SEQRES 16 a 213 CYS ILE VAL THR LYS GLU GLY ILE ARG GLU GLU THR VAL
SEQRES 17 a 213 SER LEU ARG LYS ASP
SEQRES 1 b 219 THR GLN ASN PRO MET VAL THR GLY THR SER VAL LEU GLY
SEQRES 2 b 219 VAL LYS PHE GLU GLY GLY VAL VAL ILE ALA ALA ASP MET
SEQRES 3 b 219 LEU GLY SER TYR GLY SER LEU ALA ARG PHE ARG ASN ILE
SEQRES 4 b 219 SER ARG ILE MET ARG VAL ASN ASN SER THR MET LEU GLY
SEQRES 5 b 219 ALA SER GLY ASP TYR ALA ASP PHE GLN TYR LEU LYS GLN
SEQRES 6 b 219 VAL LEU GLY GLN MET VAL ILE ASP GLU GLU LEU LEU GLY
SEQRES 7 b 219 ASP GLY HIS SER TYR SER PRO ARG ALA ILE HIS SER TRP
SEQRES 8 b 219 LEU THR ARG ALA MET TYR SER ARG ARG SER LYS MET ASN
SEQRES 9 b 219 PRO LEU TRP ASN THR MET VAL ILE GLY GLY TYR ALA ASP
SEQRES 10 b 219 GLY GLU SER PHE LEU GLY TYR VAL ASP MET LEU GLY VAL
SEQRES 11 b 219 ALA TYR GLU ALA PRO SER LEU ALA THR GLY TYR GLY ALA
SEQRES 12 b 219 TYR LEU ALA GLN PRO LEU LEU ARG GLU VAL LEU GLU LYS
SEQRES 13 b 219 GLN PRO VAL LEU SER GLN THR GLU ALA ARG ASP LEU VAL
SEQRES 14 b 219 GLU ARG CYS MET ARG VAL LEU TYR TYR ARG ASP ALA ARG
SEQRES 15 b 219 SER TYR ASN ARG PHE GLN ILE ALA THR VAL THR GLU LYS
SEQRES 16 b 219 GLY VAL GLU ILE GLU GLY PRO LEU SER THR GLU THR ASN
SEQRES 17 b 219 TRP ASP ILE ALA HIS MET ILE SER GLY PHE GLU
HELIX 1 AA1 GLN A 24 ALA A 31 1 8
HELIX 2 AA2 ILE A 32 GLY A 36 5 5
HELIX 3 AA3 MET A 83 GLY A 106 1 24
HELIX 4 AA4 PRO A 110 THR A 126 1 17
HELIX 5 AA5 LYS A 171 GLU A 180 1 10
HELIX 6 AA6 LYS A 185 TRP A 189 5 5
HELIX 7 AA7 PHE A 191 GLN A 193 5 3
HELIX 8 AA8 THR A 194 SER A 207 1 14
HELIX 9 AA9 THR A 231 VAL A 240 1 10
HELIX 10 AB1 LEU B 18 ALA B 29 1 12
HELIX 11 AB2 MET B 78 GLN B 101 1 24
HELIX 12 AB3 PRO B 105 TYR B 120 1 16
HELIX 13 AB4 ASN B 165 ARG B 176 1 12
HELIX 14 AB5 GLU B 182 GLU B 196 1 15
HELIX 15 AB6 THR B 221 ALA B 230 1 10
HELIX 16 AB7 LEU C 18 GLY C 29 1 12
HELIX 17 AB8 ILE C 79 GLN C 102 1 24
HELIX 18 AB9 PRO C 106 TYR C 121 1 16
HELIX 19 AC1 ASN C 167 LYS C 176 1 10
HELIX 20 AC2 THR C 185 THR C 200 1 16
HELIX 21 AC3 LYS C 229 GLU C 244 1 16
HELIX 22 AC4 ALA C 245 GLU C 248 5 4
HELIX 23 AC5 LEU D 16 LYS D 27 1 12
HELIX 24 AC6 GLU D 56 VAL D 59 5 4
HELIX 25 AC7 LEU D 76 GLU D 99 1 24
HELIX 26 AC8 THR D 103 TYR D 118 1 16
HELIX 27 AC9 GLY D 164 TYR D 176 1 13
HELIX 28 AD1 THR D 183 GLU D 197 1 15
HELIX 29 AD2 ASN D 221 GLU D 231 1 11
HELIX 30 AD3 LEU E 21 LYS E 32 1 12
HELIX 31 AD4 PRO E 61 ILE E 64 5 4
HELIX 32 AD5 LEU E 81 ASN E 104 1 24
HELIX 33 AD6 THR E 108 SER E 117 1 10
HELIX 34 AD7 ALA E 173 TYR E 185 1 13
HELIX 35 AD8 THR E 190 MET E 206 1 17
HELIX 36 AD9 THR E 230 ILE E 241 1 12
HELIX 37 AE1 ILE F 19 LYS F 30 1 12
HELIX 38 AE2 LEU F 77 PHE F 99 1 23
HELIX 39 AE3 PRO F 104 GLN F 117 1 14
HELIX 40 AE4 ILE F 118 GLN F 121 5 4
HELIX 41 AE5 SER F 165 MET F 176 1 12
HELIX 42 AE6 SER F 177 CYS F 182 5 6
HELIX 43 AE7 ASN F 183 GLU F 197 1 15
HELIX 44 AE8 VAL G 20 MET G 27 1 8
HELIX 45 AE9 MET G 27 ASN G 32 1 6
HELIX 46 AF1 LEU G 80 GLY G 103 1 24
HELIX 47 AF2 PRO G 107 ALA G 121 1 15
HELIX 48 AF3 ALA G 168 LYS G 178 1 11
HELIX 49 AF4 THR G 185 HIS G 201 1 17
HELIX 50 AF5 LEU G 219 ASN G 221 5 3
HELIX 51 AF6 PRO G 228 SER G 242 1 15
HELIX 52 AF7 SER H 48 ASN H 71 1 24
HELIX 53 AF8 LEU H 75 TYR H 90 1 16
HELIX 54 AF9 GLY H 129 TYR H 134 5 6
HELIX 55 AG1 ILE H 135 THR H 142 1 8
HELIX 56 AG2 THR H 148 ASP H 167 1 20
HELIX 57 AG3 THR I 48 GLY I 71 1 24
HELIX 58 AG4 ARG I 75 TYR I 90 1 16
HELIX 59 AG5 GLY I 130 PHE I 142 1 13
HELIX 60 AG6 GLU I 147 PHE I 164 1 18
HELIX 61 AG7 LEU J 55 GLU J 77 1 23
HELIX 62 AG8 LYS J 82 LYS J 97 1 16
HELIX 63 AG9 CYS J 141 TRP J 153 1 13
HELIX 64 AH1 ASP J 158 ASP J 175 1 18
HELIX 65 AH2 GLY K 51 PHE K 56 1 6
HELIX 66 AH3 PHE K 56 GLY K 72 1 17
HELIX 67 AH4 SER K 76 ASP K 90 1 15
HELIX 68 AH5 GLY K 135 LEU K 140 1 6
HELIX 69 AH6 ILE K 142 TYR K 147 1 6
HELIX 70 AH7 SER K 152 PHE K 171 1 20
HELIX 71 AH8 GLY L 48 LYS L 71 1 24
HELIX 72 AH9 SER L 75 GLN L 89 1 15
HELIX 73 AI1 GLY L 131 TYR L 143 1 13
HELIX 74 AI2 GLU L 148 ASP L 167 1 20
HELIX 75 AI3 ASN L 191 TYR L 199 1 9
HELIX 76 AI4 PHE M 57 ASN M 80 1 24
HELIX 77 AI5 THR M 84 ARG M 99 1 16
HELIX 78 AI6 ALA M 141 VAL M 153 1 13
HELIX 79 AI7 SER M 167 ASP M 186 1 20
HELIX 80 AI8 TYR N 57 GLY N 78 1 22
HELIX 81 AI9 SER N 84 LYS N 102 1 19
HELIX 82 AJ1 TYR N 141 ALA N 146 1 6
HELIX 83 AJ2 ALA N 146 GLN N 157 1 12
HELIX 84 AJ3 SER N 161 ASP N 180 1 20
HELIX 85 AJ4 GLN O 24 ALA O 31 1 8
HELIX 86 AJ5 ILE O 32 GLY O 36 5 5
HELIX 87 AJ6 MET O 83 GLY O 106 1 24
HELIX 88 AJ7 PRO O 110 THR O 126 1 17
HELIX 89 AJ8 LYS O 171 GLU O 180 1 10
HELIX 90 AJ9 LYS O 185 TRP O 189 5 5
HELIX 91 AK1 PHE O 191 GLN O 193 5 3
HELIX 92 AK2 THR O 194 SER O 207 1 14
HELIX 93 AK3 THR O 231 VAL O 240 1 10
HELIX 94 AK4 LEU P 18 ALA P 29 1 12
HELIX 95 AK5 MET P 78 GLN P 101 1 24
HELIX 96 AK6 PRO P 105 TYR P 120 1 16
HELIX 97 AK7 ASN P 165 ARG P 176 1 12
HELIX 98 AK8 GLU P 182 GLU P 196 1 15
HELIX 99 AK9 THR P 221 ALA P 230 1 10
HELIX 100 AL1 LEU Q 18 GLY Q 29 1 12
HELIX 101 AL2 ILE Q 79 GLN Q 102 1 24
HELIX 102 AL3 PRO Q 106 TYR Q 121 1 16
HELIX 103 AL4 ASN Q 167 LYS Q 176 1 10
HELIX 104 AL5 THR Q 185 THR Q 200 1 16
HELIX 105 AL6 LYS Q 229 GLU Q 244 1 16
HELIX 106 AL7 ALA Q 245 GLU Q 248 5 4
HELIX 107 AL8 LEU R 16 LYS R 27 1 12
HELIX 108 AL9 GLU R 56 VAL R 59 5 4
HELIX 109 AM1 LEU R 76 GLU R 99 1 24
HELIX 110 AM2 THR R 103 TYR R 118 1 16
HELIX 111 AM3 GLY R 164 TYR R 176 1 13
HELIX 112 AM4 THR R 183 GLU R 197 1 15
HELIX 113 AM5 ASN R 221 GLU R 231 1 11
HELIX 114 AM6 LEU S 21 LYS S 32 1 12
HELIX 115 AM7 PRO S 61 ILE S 64 5 4
HELIX 116 AM8 LEU S 81 ASN S 104 1 24
HELIX 117 AM9 THR S 108 SER S 117 1 10
HELIX 118 AN1 ALA S 173 TYR S 185 1 13
HELIX 119 AN2 THR S 190 MET S 206 1 17
HELIX 120 AN3 THR S 230 ILE S 241 1 12
HELIX 121 AN4 ILE T 19 LYS T 30 1 12
HELIX 122 AN5 LEU T 77 PHE T 99 1 23
HELIX 123 AN6 PRO T 104 GLN T 117 1 14
HELIX 124 AN7 ILE T 118 GLN T 121 5 4
HELIX 125 AN8 SER T 165 MET T 176 1 12
HELIX 126 AN9 SER T 177 CYS T 182 5 6
HELIX 127 AO1 ASN T 183 GLU T 197 1 15
HELIX 128 AO2 VAL U 20 MET U 27 1 8
HELIX 129 AO3 MET U 27 ASN U 32 1 6
HELIX 130 AO4 LEU U 80 GLY U 103 1 24
HELIX 131 AO5 PRO U 107 ALA U 121 1 15
HELIX 132 AO6 ALA U 168 LYS U 178 1 11
HELIX 133 AO7 THR U 185 HIS U 201 1 17
HELIX 134 AO8 LEU U 219 ASN U 221 5 3
HELIX 135 AO9 PRO U 228 SER U 242 1 15
HELIX 136 AP1 SER V 48 ASN V 71 1 24
HELIX 137 AP2 LEU V 75 TYR V 90 1 16
HELIX 138 AP3 GLY V 129 TYR V 134 5 6
HELIX 139 AP4 ILE V 135 THR V 142 1 8
HELIX 140 AP5 THR V 148 ASP V 167 1 20
HELIX 141 AP6 THR W 48 GLY W 71 1 24
HELIX 142 AP7 ARG W 75 TYR W 90 1 16
HELIX 143 AP8 GLY W 130 PHE W 142 1 13
HELIX 144 AP9 GLU W 147 PHE W 164 1 18
HELIX 145 AQ1 LEU X 55 GLU X 77 1 23
HELIX 146 AQ2 LYS X 82 LYS X 97 1 16
HELIX 147 AQ3 CYS X 141 TRP X 153 1 13
HELIX 148 AQ4 ASP X 158 ASP X 175 1 18
HELIX 149 AQ5 GLY Y 51 PHE Y 56 1 6
HELIX 150 AQ6 PHE Y 56 GLY Y 72 1 17
HELIX 151 AQ7 SER Y 76 ASP Y 90 1 15
HELIX 152 AQ8 GLY Y 135 LEU Y 140 1 6
HELIX 153 AQ9 ILE Y 142 TYR Y 147 1 6
HELIX 154 AR1 SER Y 152 PHE Y 171 1 20
HELIX 155 AR2 GLY Z 48 LYS Z 71 1 24
HELIX 156 AR3 SER Z 75 GLN Z 89 1 15
HELIX 157 AR4 GLY Z 131 TYR Z 143 1 13
HELIX 158 AR5 GLU Z 148 ASP Z 167 1 20
HELIX 159 AR6 ASN Z 191 TYR Z 199 1 9
HELIX 160 AR7 PHE a 57 ASN a 80 1 24
HELIX 161 AR8 THR a 84 ARG a 99 1 16
HELIX 162 AR9 ALA a 141 VAL a 153 1 13
HELIX 163 AS1 SER a 167 ASP a 186 1 20
HELIX 164 AS2 TYR b 57 GLY b 78 1 22
HELIX 165 AS3 SER b 84 LYS b 102 1 19
HELIX 166 AS4 TYR b 141 ALA b 146 1 6
HELIX 167 AS5 ALA b 146 GLN b 157 1 12
HELIX 168 AS6 SER b 161 ASP b 180 1 20
SHEET 1 AA1 5 ALA A 165 GLY A 169 0
SHEET 2 AA1 5 THR A 38 ARG A 43 -1 N ALA A 41 O THR A 166
SHEET 3 AA1 5 CYS A 47 GLN A 53 -1 O VAL A 51 N VAL A 40
SHEET 4 AA1 5 ILE A 215 THR A 221 -1 O GLY A 218 N ILE A 50
SHEET 5 AA1 5 ARG A 228 ILE A 229 -1 O ARG A 228 N VAL A 219
SHEET 1 AA2 5 LEU A 69 LYS A 71 0
SHEET 2 AA2 5 GLY A 77 GLY A 82 -1 O CYS A 78 N PHE A 70
SHEET 3 AA2 5 CYS A 136 ILE A 143 -1 O ILE A 141 N GLY A 77
SHEET 4 AA2 5 PRO A 149 CYS A 154 -1 O TYR A 152 N LEU A 140
SHEET 5 AA2 5 GLY A 162 PHE A 163 -1 O PHE A 163 N VAL A 151
SHEET 1 AA3 5 ALA B 159 MET B 162 0
SHEET 2 AA3 5 SER B 34 LYS B 38 -1 N SER B 34 O MET B 162
SHEET 3 AA3 5 VAL B 43 GLU B 48 -1 O ALA B 46 N VAL B 35
SHEET 4 AA3 5 ILE B 207 ASN B 213 -1 O GLY B 210 N LEU B 45
SHEET 5 AA3 5 GLY B 216 ARG B 219 -1 O ARG B 218 N ILE B 211
SHEET 1 AA4 5 VAL B 64 PRO B 66 0
SHEET 2 AA4 5 ILE B 71 GLY B 77 -1 O LEU B 73 N GLU B 65
SHEET 3 AA4 5 VAL B 131 ASN B 139 -1 O CYS B 136 N GLY B 72
SHEET 4 AA4 5 ARG B 142 SER B 148 -1 O PHE B 146 N ILE B 135
SHEET 5 AA4 5 TYR B 154 ALA B 156 -1 O PHE B 155 N GLN B 147
SHEET 1 AA5 5 ALA C 161 ILE C 164 0
SHEET 2 AA5 5 CYS C 34 LEU C 38 -1 N CYS C 34 O ILE C 164
SHEET 3 AA5 5 VAL C 43 GLU C 48 -1 O ALA C 46 N LEU C 35
SHEET 4 AA5 5 VAL C 211 ARG C 218 -1 O ALA C 214 N LEU C 45
SHEET 5 AA5 5 THR C 223 VAL C 227 -1 O VAL C 224 N THR C 217
SHEET 1 AA6 5 MET C 72 GLY C 78 0
SHEET 2 AA6 5 VAL C 132 ASP C 140 -1 O ILE C 137 N ALA C 73
SHEET 3 AA6 5 GLY C 144 SER C 150 -1 O GLN C 146 N GLY C 138
SHEET 4 AA6 5 TYR C 156 TRP C 159 -1 O TRP C 159 N LEU C 147
SHEET 5 AA6 5 GLN D 54 ASP D 55 -1 O ASP D 55 N GLY C 158
SHEET 1 AA7 5 ALA D 158 ILE D 161 0
SHEET 2 AA7 5 ALA D 32 ARG D 36 -1 N ALA D 32 O ILE D 161
SHEET 3 AA7 5 VAL D 41 VAL D 45 -1 O GLY D 44 N VAL D 33
SHEET 4 AA7 5 GLU D 207 MET D 211 -1 O ALA D 209 N LEU D 43
SHEET 5 AA7 5 LYS D 218 ILE D 219 -1 O LYS D 218 N VAL D 210
SHEET 1 AA8 5 VAL D 69 GLY D 75 0
SHEET 2 AA8 5 ILE D 129 PHE D 136 -1 O LEU D 132 N ALA D 72
SHEET 3 AA8 5 PRO D 142 THR D 147 -1 O TYR D 145 N ILE D 133
SHEET 4 AA8 5 TYR D 153 TRP D 156 -1 O TRP D 156 N LEU D 144
SHEET 5 AA8 5 MET E 59 GLU E 60 -1 O GLU E 60 N ALA D 155
SHEET 1 AA9 5 ALA E 167 ILE E 170 0
SHEET 2 AA9 5 ALA E 37 THR E 42 -1 N ALA E 37 O ILE E 170
SHEET 3 AA9 5 GLY E 45 GLU E 51 -1 O ALA E 49 N ILE E 38
SHEET 4 AA9 5 ILE E 215 VAL E 220 -1 O ALA E 218 N LEU E 48
SHEET 5 AA9 5 PHE E 226 MET E 228 -1 O HIS E 227 N THR E 219
SHEET 1 AB1 6 ILE E 67 GLU E 69 0
SHEET 2 AB1 6 ILE E 74 GLY E 80 -1 O CYS E 76 N VAL E 68
SHEET 3 AB1 6 VAL E 139 ASP E 147 -1 O LEU E 142 N ALA E 77
SHEET 4 AB1 6 GLY E 150 MET E 156 -1 O GLN E 152 N GLY E 145
SHEET 5 AB1 6 PHE E 162 CYS E 165 -1 O CYS E 165 N LEU E 153
SHEET 6 AB1 6 ALA F 57 ALA F 58 -1 O ALA F 58 N GLN E 164
SHEET 1 AB2 5 ALA F 158 ILE F 161 0
SHEET 2 AB2 5 THR F 35 LYS F 39 -1 N GLY F 37 O MET F 159
SHEET 3 AB2 5 HIS F 43 LEU F 49 -1 O VAL F 47 N VAL F 36
SHEET 4 AB2 5 VAL F 210 GLY F 216 -1 O GLY F 213 N LEU F 46
SHEET 5 AB2 5 THR F 222 TYR F 224 -1 O THR F 222 N ILE F 214
SHEET 1 AB3 5 ILE F 63 HIS F 65 0
SHEET 2 AB3 5 ILE F 70 GLY F 76 -1 O ILE F 72 N LEU F 64
SHEET 3 AB3 5 VAL F 130 ASP F 138 -1 O GLY F 131 N ALA F 75
SHEET 4 AB3 5 GLY F 141 THR F 147 -1 O PHE F 145 N ILE F 134
SHEET 5 AB3 5 TYR F 153 CYS F 156 -1 O PHE F 154 N GLN F 146
SHEET 1 AB4 5 GLY G 162 ILE G 165 0
SHEET 2 AB4 5 ALA G 36 ARG G 40 -1 N ALA G 36 O ILE G 165
SHEET 3 AB4 5 GLY G 44 LEU G 52 -1 O GLY G 48 N ILE G 37
SHEET 4 AB4 5 PHE G 209 GLY G 217 -1 O SER G 214 N PHE G 47
SHEET 5 AB4 5 HIS G 224 ILE G 226 -1 O GLU G 225 N TRP G 215
SHEET 1 AB5 5 LEU G 66 ASN G 68 0
SHEET 2 AB5 5 VAL G 73 GLY G 79 -1 O MET G 75 N PHE G 67
SHEET 3 AB5 5 CYS G 133 SER G 141 -1 O MET G 136 N ALA G 76
SHEET 4 AB5 5 GLY G 145 ILE G 151 -1 O TYR G 149 N LEU G 137
SHEET 5 AB5 5 SER G 157 GLY G 159 -1 O TYR G 158 N MET G 150
SHEET 1 AB6 5 PHE H 125 GLY H 128 0
SHEET 2 AB6 5 ILE H 3 PHE H 8 -1 N ILE H 3 O GLY H 128
SHEET 3 AB6 5 GLY H 11 ALA H 16 -1 O VAL H 13 N VAL H 6
SHEET 4 AB6 5 ILE H 174 ALA H 180 -1 O ALA H 177 N LEU H 14
SHEET 5 AB6 5 VAL H 184 LEU H 189 -1 O LEU H 189 N ILE H 174
SHEET 1 AB7 2 THR H 20 THR H 22 0
SHEET 2 AB7 2 TYR H 25 ASN H 28 -1 O TYR H 25 N THR H 22
SHEET 1 AB8 5 LEU H 34 HIS H 38 0
SHEET 2 AB8 5 ILE H 41 GLY H 47 -1 O ILE H 41 N HIS H 38
SHEET 3 AB8 5 ALA H 96 ASP H 104 -1 O ILE H 99 N CYS H 44
SHEET 4 AB8 5 GLY H 108 VAL H 114 -1 O TYR H 112 N ILE H 100
SHEET 5 AB8 5 VAL H 121 ARG H 122 -1 O VAL H 121 N SER H 113
SHEET 1 AB9 5 TYR I 124 GLY I 128 0
SHEET 2 AB9 5 THR I 2 TYR I 8 -1 N ILE I 3 O MET I 127
SHEET 3 AB9 5 GLY I 11 ASP I 17 -1 O GLY I 15 N ALA I 4
SHEET 4 AB9 5 ILE I 173 SER I 179 -1 O ILE I 178 N ILE I 12
SHEET 5 AB9 5 LEU I 183 THR I 190 -1 O LEU I 186 N LEU I 175
SHEET 1 AC1 2 ALA I 20 THR I 21 0
SHEET 2 AC1 2 VAL I 26 ASP I 28 -1 O ALA I 27 N ALA I 20
SHEET 1 AC2 4 ILE I 34 SER I 38 0
SHEET 2 AC2 4 ILE I 41 GLY I 47 -1 O CYS I 43 N HIS I 35
SHEET 3 AC2 4 ALA I 96 ASP I 104 -1 O ALA I 97 N ALA I 46
SHEET 4 AC2 4 GLY I 107 LEU I 110 -1 O HIS I 109 N GLY I 102
SHEET 1 AC3 2 SER I 112 ILE I 113 0
SHEET 2 AC3 2 THR I 119 ASP I 120 -1 O ASP I 120 N SER I 112
SHEET 1 AC4 6 THR I 213 PRO I 218 0
SHEET 2 AC4 6 LYS J 193 LEU J 199 -1 O THR J 196 N LYS I 215
SHEET 3 AC4 6 VAL J 184 ILE J 189 -1 N ILE J 188 O THR J 195
SHEET 4 AC4 6 VAL J 19 ASP J 24 -1 N VAL J 19 O ILE J 189
SHEET 5 AC4 6 ALA J 9 LYS J 14 -1 N MET J 13 O ALA J 20
SHEET 6 AC4 6 PHE J 135 GLY J 139 -1 O SER J 138 N VAL J 10
SHEET 1 AC5 2 PHE J 27 ILE J 29 0
SHEET 2 AC5 2 GLN J 32 THR J 35 -1 O GLN J 32 N ILE J 29
SHEET 1 AC6 5 ILE J 41 PRO J 43 0
SHEET 2 AC6 5 LEU J 48 GLY J 51 -1 O ILE J 50 N PHE J 42
SHEET 3 AC6 5 VAL J 107 LEU J 111 -1 O VAL J 107 N GLY J 51
SHEET 4 AC6 5 PRO J 118 LEU J 123 -1 O PHE J 119 N GLY J 110
SHEET 5 AC6 5 PRO J 129 THR J 132 -1 O MET J 130 N SER J 122
SHEET 1 AC7 5 PHE K 129 HIS K 132 0
SHEET 2 AC7 5 LEU K 4 GLN K 8 -1 N GLY K 6 O ALA K 130
SHEET 3 AC7 5 VAL K 13 ASP K 18 -1 O LEU K 14 N ILE K 7
SHEET 4 AC7 5 PHE K 178 ILE K 182 -1 O ARG K 181 N VAL K 15
SHEET 5 AC7 5 HIS K 189 ASP K 190 -1 O HIS K 189 N ILE K 182
SHEET 1 AC8 5 MET K 35 LYS K 37 0
SHEET 2 AC8 5 ILE K 42 GLY K 48 -1 O LEU K 44 N PHE K 36
SHEET 3 AC8 5 VAL K 100 ASP K 108 -1 O ASN K 101 N VAL K 47
SHEET 4 AC8 5 GLY K 112 MET K 118 -1 O TYR K 116 N LEU K 104
SHEET 5 AC8 5 ALA K 125 LYS K 126 -1 O ALA K 125 N TYR K 117
SHEET 1 AC9 5 THR L 125 GLY L 129 0
SHEET 2 AC9 5 THR L 2 PHE L 8 -1 N ALA L 5 O PHE L 126
SHEET 3 AC9 5 GLY L 11 ALA L 16 -1 O ALA L 15 N LEU L 4
SHEET 4 AC9 5 ASN L 175 ARG L 180 -1 O TYR L 177 N VAL L 14
SHEET 5 AC9 5 GLY L 183 SER L 188 -1 O ILE L 185 N HIS L 178
SHEET 1 AD1 2 ALA L 20 ALA L 22 0
SHEET 2 AD1 2 TYR L 25 SER L 28 -1 O SER L 28 N ALA L 20
SHEET 1 AD2 5 VAL L 34 ASN L 38 0
SHEET 2 AD2 5 LEU L 41 THR L 44 -1 O GLY L 43 N ILE L 35
SHEET 3 AD2 5 THR L 99 ASP L 105 -1 O CYS L 102 N LEU L 42
SHEET 4 AD2 5 GLY L 108 VAL L 114 -1 O GLY L 110 N GLY L 103
SHEET 5 AD2 5 ARG L 120 SER L 122 -1 O ILE L 121 N TYR L 113
SHEET 1 AD3 5 PHE M 135 GLY M 139 0
SHEET 2 AD3 5 THR M 11 ALA M 16 -1 N ILE M 12 O GLY M 138
SHEET 3 AD3 5 ALA M 21 ASP M 26 -1 O ALA M 24 N LEU M 13
SHEET 4 AD3 5 ALA M 192 THR M 199 -1 O CYS M 196 N VAL M 23
SHEET 5 AD3 5 GLY M 202 SER M 209 -1 O GLY M 202 N THR M 199
SHEET 1 AD4 2 LEU M 29 GLU M 31 0
SHEET 2 AD4 2 SER M 34 THR M 37 -1 O HIS M 36 N LEU M 29
SHEET 1 AD5 5 CYS M 43 THR M 47 0
SHEET 2 AD5 5 THR M 50 GLY M 56 -1 O ILE M 52 N TYR M 44
SHEET 3 AD5 5 VAL M 106 LEU M 113 -1 O TYR M 107 N SER M 55
SHEET 4 AD5 5 GLY M 119 PHE M 124 -1 O ALA M 120 N GLY M 112
SHEET 5 AD5 5 TYR M 130 ASP M 133 -1 O GLN M 131 N SER M 123
SHEET 1 AD6 2 THR N 7 GLY N 8 0
SHEET 2 AD6 2 GLY N 55 ASP N 56 -1 O GLY N 55 N GLY N 8
SHEET 1 AD7 5 SER N 136 ALA N 138 0
SHEET 2 AD7 5 VAL N 11 PHE N 16 -1 N GLY N 13 O LEU N 137
SHEET 3 AD7 5 GLY N 19 ASP N 25 -1 O ALA N 23 N LEU N 12
SHEET 4 AD7 5 ARG N 186 THR N 193 -1 O VAL N 192 N VAL N 20
SHEET 5 AD7 5 GLY N 196 ILE N 199 -1 O GLU N 198 N THR N 191
SHEET 1 AD8 5 SER N 136 ALA N 138 0
SHEET 2 AD8 5 VAL N 11 PHE N 16 -1 N GLY N 13 O LEU N 137
SHEET 3 AD8 5 GLY N 19 ASP N 25 -1 O ALA N 23 N LEU N 12
SHEET 4 AD8 5 ARG N 186 THR N 193 -1 O VAL N 192 N VAL N 20
SHEET 5 AD8 5 LEU N 203 SER N 204 -1 O LEU N 203 N PHE N 187
SHEET 1 AD9 2 GLY N 28 SER N 29 0
SHEET 2 AD9 2 ALA N 34 PHE N 36 -1 O PHE N 36 N GLY N 28
SHEET 1 AE1 5 ILE N 42 ASN N 46 0
SHEET 2 AE1 5 THR N 49 GLY N 52 -1 O LEU N 51 N MET N 43
SHEET 3 AE1 5 VAL N 111 ALA N 116 -1 O VAL N 111 N GLY N 52
SHEET 4 AE1 5 GLU N 119 VAL N 125 -1 O GLY N 123 N ILE N 112
SHEET 5 AE1 5 ALA N 131 GLU N 133 -1 O TYR N 132 N TYR N 124
SHEET 1 AE2 5 ALA O 165 GLY O 169 0
SHEET 2 AE2 5 THR O 38 ARG O 43 -1 N ALA O 41 O THR O 166
SHEET 3 AE2 5 CYS O 47 GLN O 53 -1 O VAL O 51 N VAL O 40
SHEET 4 AE2 5 ILE O 215 THR O 221 -1 O GLY O 218 N ILE O 50
SHEET 5 AE2 5 ARG O 228 ILE O 229 -1 O ARG O 228 N VAL O 219
SHEET 1 AE3 5 LEU O 69 LYS O 71 0
SHEET 2 AE3 5 GLY O 77 GLY O 82 -1 O CYS O 78 N PHE O 70
SHEET 3 AE3 5 CYS O 136 ILE O 143 -1 O ILE O 141 N GLY O 77
SHEET 4 AE3 5 PRO O 149 CYS O 154 -1 O TYR O 152 N LEU O 140
SHEET 5 AE3 5 GLY O 162 PHE O 163 -1 O PHE O 163 N VAL O 151
SHEET 1 AE4 5 ALA P 159 MET P 162 0
SHEET 2 AE4 5 SER P 34 LYS P 38 -1 N SER P 34 O MET P 162
SHEET 3 AE4 5 VAL P 43 GLU P 48 -1 O ALA P 46 N VAL P 35
SHEET 4 AE4 5 ILE P 207 ASN P 213 -1 O GLY P 210 N LEU P 45
SHEET 5 AE4 5 GLY P 216 ARG P 219 -1 O ARG P 218 N ILE P 211
SHEET 1 AE5 5 VAL P 64 PRO P 66 0
SHEET 2 AE5 5 ILE P 71 GLY P 77 -1 O LEU P 73 N GLU P 65
SHEET 3 AE5 5 VAL P 131 ASN P 139 -1 O CYS P 136 N GLY P 72
SHEET 4 AE5 5 ARG P 142 SER P 148 -1 O PHE P 146 N ILE P 135
SHEET 5 AE5 5 TYR P 154 ALA P 156 -1 O PHE P 155 N GLN P 147
SHEET 1 AE6 5 ALA Q 161 ILE Q 164 0
SHEET 2 AE6 5 CYS Q 34 LEU Q 38 -1 N CYS Q 34 O ILE Q 164
SHEET 3 AE6 5 VAL Q 43 GLU Q 48 -1 O ALA Q 46 N LEU Q 35
SHEET 4 AE6 5 VAL Q 211 ARG Q 218 -1 O ALA Q 214 N LEU Q 45
SHEET 5 AE6 5 THR Q 223 VAL Q 227 -1 O VAL Q 224 N THR Q 217
SHEET 1 AE7 5 MET Q 72 GLY Q 78 0
SHEET 2 AE7 5 VAL Q 132 ASP Q 140 -1 O ILE Q 137 N ALA Q 73
SHEET 3 AE7 5 GLY Q 144 SER Q 150 -1 O GLN Q 146 N GLY Q 138
SHEET 4 AE7 5 TYR Q 156 TRP Q 159 -1 O TRP Q 159 N LEU Q 147
SHEET 5 AE7 5 GLN R 54 ASP R 55 -1 O ASP R 55 N GLY Q 158
SHEET 1 AE8 5 ALA R 158 ILE R 161 0
SHEET 2 AE8 5 ALA R 32 ARG R 36 -1 N ALA R 32 O ILE R 161
SHEET 3 AE8 5 VAL R 41 VAL R 45 -1 O GLY R 44 N VAL R 33
SHEET 4 AE8 5 GLU R 207 MET R 211 -1 O ALA R 209 N LEU R 43
SHEET 5 AE8 5 LYS R 218 ILE R 219 -1 O LYS R 218 N VAL R 210
SHEET 1 AE9 5 VAL R 69 GLY R 75 0
SHEET 2 AE9 5 ILE R 129 PHE R 136 -1 O LEU R 132 N ALA R 72
SHEET 3 AE9 5 PRO R 142 THR R 147 -1 O TYR R 145 N ILE R 133
SHEET 4 AE9 5 TYR R 153 TRP R 156 -1 O TRP R 156 N LEU R 144
SHEET 5 AE9 5 MET S 59 GLU S 60 -1 O GLU S 60 N ALA R 155
SHEET 1 AF1 5 ALA S 167 ILE S 170 0
SHEET 2 AF1 5 ALA S 37 THR S 42 -1 N ALA S 37 O ILE S 170
SHEET 3 AF1 5 GLY S 45 GLU S 51 -1 O ALA S 49 N ILE S 38
SHEET 4 AF1 5 ILE S 215 VAL S 220 -1 O ALA S 218 N LEU S 48
SHEET 5 AF1 5 PHE S 226 MET S 228 -1 O HIS S 227 N THR S 219
SHEET 1 AF2 6 ILE S 67 GLU S 69 0
SHEET 2 AF2 6 ILE S 74 GLY S 80 -1 O CYS S 76 N VAL S 68
SHEET 3 AF2 6 VAL S 139 ASP S 147 -1 O LEU S 142 N ALA S 77
SHEET 4 AF2 6 GLY S 150 MET S 156 -1 O GLN S 152 N GLY S 145
SHEET 5 AF2 6 PHE S 162 CYS S 165 -1 O CYS S 165 N LEU S 153
SHEET 6 AF2 6 ALA T 57 ALA T 58 -1 O ALA T 58 N GLN S 164
SHEET 1 AF3 5 ALA T 158 ILE T 161 0
SHEET 2 AF3 5 THR T 35 LYS T 39 -1 N GLY T 37 O MET T 159
SHEET 3 AF3 5 HIS T 43 LEU T 49 -1 O VAL T 47 N VAL T 36
SHEET 4 AF3 5 VAL T 210 GLY T 216 -1 O GLY T 213 N LEU T 46
SHEET 5 AF3 5 THR T 222 TYR T 224 -1 O THR T 222 N ILE T 214
SHEET 1 AF4 5 ILE T 63 HIS T 65 0
SHEET 2 AF4 5 ILE T 70 GLY T 76 -1 O ILE T 72 N LEU T 64
SHEET 3 AF4 5 VAL T 130 ASP T 138 -1 O GLY T 131 N ALA T 75
SHEET 4 AF4 5 GLY T 141 THR T 147 -1 O PHE T 145 N ILE T 134
SHEET 5 AF4 5 TYR T 153 CYS T 156 -1 O PHE T 154 N GLN T 146
SHEET 1 AF5 5 GLY U 162 ILE U 165 0
SHEET 2 AF5 5 ALA U 36 ARG U 40 -1 N ALA U 36 O ILE U 165
SHEET 3 AF5 5 GLY U 44 LEU U 52 -1 O GLY U 48 N ILE U 37
SHEET 4 AF5 5 PHE U 209 GLY U 217 -1 O SER U 214 N PHE U 47
SHEET 5 AF5 5 HIS U 224 ILE U 226 -1 O GLU U 225 N TRP U 215
SHEET 1 AF6 5 LEU U 66 ASN U 68 0
SHEET 2 AF6 5 VAL U 73 GLY U 79 -1 O MET U 75 N PHE U 67
SHEET 3 AF6 5 CYS U 133 SER U 141 -1 O MET U 136 N ALA U 76
SHEET 4 AF6 5 GLY U 145 ILE U 151 -1 O TYR U 149 N LEU U 137
SHEET 5 AF6 5 SER U 157 GLY U 159 -1 O TYR U 158 N MET U 150
SHEET 1 AF7 5 PHE V 125 GLY V 128 0
SHEET 2 AF7 5 ILE V 3 PHE V 8 -1 N ILE V 3 O GLY V 128
SHEET 3 AF7 5 GLY V 11 ALA V 16 -1 O VAL V 13 N VAL V 6
SHEET 4 AF7 5 ILE V 174 ALA V 180 -1 O ALA V 177 N LEU V 14
SHEET 5 AF7 5 VAL V 184 LEU V 189 -1 O LEU V 189 N ILE V 174
SHEET 1 AF8 2 THR V 20 THR V 22 0
SHEET 2 AF8 2 TYR V 25 ASN V 28 -1 O TYR V 25 N THR V 22
SHEET 1 AF9 5 LEU V 34 HIS V 38 0
SHEET 2 AF9 5 ILE V 41 GLY V 47 -1 O ILE V 41 N HIS V 38
SHEET 3 AF9 5 ALA V 96 ASP V 104 -1 O ILE V 99 N CYS V 44
SHEET 4 AF9 5 GLY V 108 VAL V 114 -1 O TYR V 112 N ILE V 100
SHEET 5 AF9 5 VAL V 121 ARG V 122 -1 O VAL V 121 N SER V 113
SHEET 1 AG1 5 TYR W 124 GLY W 128 0
SHEET 2 AG1 5 THR W 2 TYR W 8 -1 N ILE W 3 O MET W 127
SHEET 3 AG1 5 GLY W 11 ASP W 17 -1 O GLY W 15 N ALA W 4
SHEET 4 AG1 5 ILE W 173 SER W 179 -1 O ILE W 178 N ILE W 12
SHEET 5 AG1 5 LEU W 183 THR W 190 -1 O LEU W 186 N LEU W 175
SHEET 1 AG2 2 ALA W 20 THR W 21 0
SHEET 2 AG2 2 VAL W 26 ASP W 28 -1 O ALA W 27 N ALA W 20
SHEET 1 AG3 4 ILE W 34 SER W 38 0
SHEET 2 AG3 4 ILE W 41 GLY W 47 -1 O CYS W 43 N HIS W 35
SHEET 3 AG3 4 ALA W 96 ASP W 104 -1 O ALA W 97 N ALA W 46
SHEET 4 AG3 4 GLY W 107 LEU W 110 -1 O HIS W 109 N GLY W 102
SHEET 1 AG4 2 SER W 112 ILE W 113 0
SHEET 2 AG4 2 THR W 119 ASP W 120 -1 O ASP W 120 N SER W 112
SHEET 1 AG5 6 THR W 213 PRO W 218 0
SHEET 2 AG5 6 LYS X 193 LEU X 199 -1 O THR X 196 N LYS W 215
SHEET 3 AG5 6 VAL X 184 ILE X 189 -1 N ILE X 188 O THR X 195
SHEET 4 AG5 6 VAL X 19 ASP X 24 -1 N VAL X 19 O ILE X 189
SHEET 5 AG5 6 ALA X 9 LYS X 14 -1 N MET X 13 O ALA X 20
SHEET 6 AG5 6 PHE X 135 GLY X 139 -1 O SER X 138 N VAL X 10
SHEET 1 AG6 2 PHE X 27 ILE X 29 0
SHEET 2 AG6 2 GLN X 32 THR X 35 -1 O GLN X 32 N ILE X 29
SHEET 1 AG7 5 ILE X 41 PRO X 43 0
SHEET 2 AG7 5 LEU X 48 GLY X 51 -1 O ILE X 50 N PHE X 42
SHEET 3 AG7 5 VAL X 107 LEU X 111 -1 O VAL X 107 N GLY X 51
SHEET 4 AG7 5 PRO X 118 LEU X 123 -1 O PHE X 119 N GLY X 110
SHEET 5 AG7 5 PRO X 129 THR X 132 -1 O MET X 130 N SER X 122
SHEET 1 AG8 5 PHE Y 129 HIS Y 132 0
SHEET 2 AG8 5 LEU Y 4 GLN Y 8 -1 N GLY Y 6 O ALA Y 130
SHEET 3 AG8 5 VAL Y 13 ASP Y 18 -1 O LEU Y 14 N ILE Y 7
SHEET 4 AG8 5 PHE Y 178 ILE Y 182 -1 O ARG Y 181 N VAL Y 15
SHEET 5 AG8 5 HIS Y 189 ASP Y 190 -1 O HIS Y 189 N ILE Y 182
SHEET 1 AG9 5 MET Y 35 LYS Y 37 0
SHEET 2 AG9 5 ILE Y 42 GLY Y 48 -1 O LEU Y 44 N PHE Y 36
SHEET 3 AG9 5 VAL Y 100 ASP Y 108 -1 O ASN Y 101 N VAL Y 47
SHEET 4 AG9 5 GLY Y 112 MET Y 118 -1 O TYR Y 116 N LEU Y 104
SHEET 5 AG9 5 ALA Y 125 LYS Y 126 -1 O ALA Y 125 N TYR Y 117
SHEET 1 AH1 5 THR Z 125 GLY Z 129 0
SHEET 2 AH1 5 THR Z 2 PHE Z 8 -1 N ALA Z 5 O PHE Z 126
SHEET 3 AH1 5 GLY Z 11 ALA Z 16 -1 O ALA Z 15 N LEU Z 4
SHEET 4 AH1 5 ASN Z 175 ARG Z 180 -1 O TYR Z 177 N VAL Z 14
SHEET 5 AH1 5 GLY Z 183 SER Z 188 -1 O ILE Z 185 N HIS Z 178
SHEET 1 AH2 2 ALA Z 20 ALA Z 22 0
SHEET 2 AH2 2 TYR Z 25 SER Z 28 -1 O SER Z 28 N ALA Z 20
SHEET 1 AH3 5 VAL Z 34 ASN Z 38 0
SHEET 2 AH3 5 LEU Z 41 THR Z 44 -1 O GLY Z 43 N ILE Z 35
SHEET 3 AH3 5 THR Z 99 ASP Z 105 -1 O CYS Z 102 N LEU Z 42
SHEET 4 AH3 5 GLY Z 108 VAL Z 114 -1 O GLY Z 110 N GLY Z 103
SHEET 5 AH3 5 ARG Z 120 SER Z 122 -1 O ILE Z 121 N TYR Z 113
SHEET 1 AH4 5 PHE a 135 GLY a 139 0
SHEET 2 AH4 5 THR a 11 ALA a 16 -1 N ILE a 12 O GLY a 138
SHEET 3 AH4 5 ALA a 21 ASP a 26 -1 O ALA a 24 N LEU a 13
SHEET 4 AH4 5 ALA a 192 THR a 199 -1 O CYS a 196 N VAL a 23
SHEET 5 AH4 5 GLY a 202 SER a 209 -1 O GLY a 202 N THR a 199
SHEET 1 AH5 2 LEU a 29 GLU a 31 0
SHEET 2 AH5 2 SER a 34 THR a 37 -1 O HIS a 36 N LEU a 29
SHEET 1 AH6 5 CYS a 43 THR a 47 0
SHEET 2 AH6 5 THR a 50 GLY a 56 -1 O ILE a 52 N TYR a 44
SHEET 3 AH6 5 VAL a 106 LEU a 113 -1 O TYR a 107 N SER a 55
SHEET 4 AH6 5 GLY a 119 PHE a 124 -1 O ALA a 120 N GLY a 112
SHEET 5 AH6 5 TYR a 130 ASP a 133 -1 O GLN a 131 N SER a 123
SHEET 1 AH7 2 THR b 7 GLY b 8 0
SHEET 2 AH7 2 GLY b 55 ASP b 56 -1 O GLY b 55 N GLY b 8
SHEET 1 AH8 5 SER b 136 ALA b 138 0
SHEET 2 AH8 5 VAL b 11 PHE b 16 -1 N GLY b 13 O LEU b 137
SHEET 3 AH8 5 GLY b 19 ASP b 25 -1 O ALA b 23 N LEU b 12
SHEET 4 AH8 5 ARG b 186 THR b 193 -1 O VAL b 192 N VAL b 20
SHEET 5 AH8 5 GLY b 196 ILE b 199 -1 O GLU b 198 N THR b 191
SHEET 1 AH9 5 SER b 136 ALA b 138 0
SHEET 2 AH9 5 VAL b 11 PHE b 16 -1 N GLY b 13 O LEU b 137
SHEET 3 AH9 5 GLY b 19 ASP b 25 -1 O ALA b 23 N LEU b 12
SHEET 4 AH9 5 ARG b 186 THR b 193 -1 O VAL b 192 N VAL b 20
SHEET 5 AH9 5 LEU b 203 SER b 204 -1 O LEU b 203 N PHE b 187
SHEET 1 AI1 2 GLY b 28 SER b 29 0
SHEET 2 AI1 2 ALA b 34 PHE b 36 -1 O PHE b 36 N GLY b 28
SHEET 1 AI2 5 ILE b 42 ASN b 46 0
SHEET 2 AI2 5 THR b 49 GLY b 52 -1 O LEU b 51 N MET b 43
SHEET 3 AI2 5 VAL b 111 ALA b 116 -1 O VAL b 111 N GLY b 52
SHEET 4 AI2 5 GLU b 119 VAL b 125 -1 O GLY b 123 N ILE b 112
SHEET 5 AI2 5 ALA b 131 GLU b 133 -1 O TYR b 132 N TYR b 124
CRYST1 1.000 1.000 1.000 90.00 90.00 90.00 P 1
ORIGX1 1.000000 0.000000 0.000000 0.00000
ORIGX2 0.000000 1.000000 0.000000 0.00000
ORIGX3 0.000000 0.000000 1.000000 0.00000
SCALE1 1.000000 0.000000 0.000000 0.00000
SCALE2 0.000000 1.000000 0.000000 0.00000
SCALE3 0.000000 0.000000 1.000000 0.00000
(ATOM LINES ARE NOT SHOWN.)
END
