#=GF ID DUF3857
#=GF AC PF12969.11
#=GF DE Domain of Unknown Function with PDB structure (DUF3857)
#=GF AU Ellrott K;0000-0002-6573-5900
#=GF SE JCSG structure PDB:3KD4
#=GF GA 24.60 24.60;
#=GF TC 24.60 24.60;
#=GF NC 24.50 24.50;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF WK Domain_of_unknown_function
#=GF CL CL0672
#=GF DR INTERPRO; IPR024618;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This family is based on the first domain of the PDB structure
#=GF CC PDB:3KD4(residues 1-228). It is structurally similar to domains
#=GF CC in other hydrolases, eg. M1 family aminopeptidase (3ebi, Z=10,
#=GF CC rmsd 3.6A for 152 CA, seq id 12%), despite lack of any
#=GF CC significant sequence similarity.
#=GF SQ 2625
#=GS A0A1G6H0K4_9BURK/64-230 AC A0A1G6H0K4.1
#=GS A0A5C4SHB6_9FLAO/61-210 AC A0A5C4SHB6.1
#=GS A0A4R6SSN0_9SPHI/74-228 AC A0A4R6SSN0.1
#=GS A0A1B8U7G8_9FLAO/57-218 AC A0A1B8U7G8.1
#=GS A0A3M9NAR4_9BACT/63-221 AC A0A3M9NAR4.1
#=GS A0A839GUA6_9BACT/70-258 AC A0A839GUA6.1
#=GS A0A364Y0G9_9BACT/90-234 AC A0A364Y0G9.1
#=GS A0A239HMS5_9BACT/66-226 AC A0A239HMS5.1
#=GS A0A0C5WPR0_9FLAO/65-212 AC A0A0C5WPR0.1
#=GS A0A0A2MW47_9FLAO/69-229 AC A0A0A2MW47.1
#=GS A0A6B3PVJ9_9BACT/51-214 AC A0A6B3PVJ9.1
#=GS A0A127B115_9BACT/694-842 AC A0A127B115.1
#=GS A0A2S7T7T1_9FLAO/67-216 AC A0A2S7T7T1.1
#=GS A0A6C0GPB9_9BACT/74-263 AC A0A6C0GPB9.1
#=GS A0A2V4A262_9BACT/57-218 AC A0A2V4A262.1
#=GS A0A5C6ZKF3_9FLAO/63-219 AC A0A5C6ZKF3.1
#=GS A0A397NJQ1_9SPHN/62-227 AC A0A397NJQ1.1
#=GS A0A3N4MAR0_9BACT/83-258 AC A0A3N4MAR0.1
#=GS A0A2T5J5V6_9SPHI/64-217 AC A0A2T5J5V6.1
#=GS A0A172U5V6_9GAMM/51-224 AC A0A172U5V6.1
#=GS A0A1I6MJJ3_9BACT/57-210 AC A0A1I6MJJ3.1
#=GS A0A0A2M5Q6_9FLAO/66-216 AC A0A0A2M5Q6.1
#=GS A6ESD6_9BACT/63-226 AC A6ESD6.1
#=GS A0A1R1MN35_9BACT/38-207 AC A0A1R1MN35.1
#=GS A0A1I7GMX0_9FLAO/60-231 AC A0A1I7GMX0.1
#=GS A0A1S9PF61_9SPHI/51-216 AC A0A1S9PF61.1
#=GS A0A1D7XXW0_9FLAO/54-216 AC A0A1D7XXW0.1
#=GS A0A1M7KUU5_9BACT/53-216 AC A0A1M7KUU5.1
#=GS A0A2S5AD06_9FLAO/67-225 AC A0A2S5AD06.1
#=GS A0A1G9XS96_9BACT/48-212 AC A0A1G9XS96.1
#=GS A0A2W1N624_9FLAO/65-231 AC A0A2W1N624.1
#=GS A0A0D5YUZ2_9FLAO/52-205 AC A0A0D5YUZ2.1
#=GS H8MHU3_CORCM/86-256 AC H8MHU3.1
#=GS A0A5B8ULF6_9BACT/56-219 AC A0A5B8ULF6.1
#=GS A0A838ZL98_9FLAO/60-221 AC A0A838ZL98.1
#=GS A0A4R0WPB3_9BURK/53-220 AC A0A4R0WPB3.1
#=GS A0A2D1U1J5_9SPHI/51-214 AC A0A2D1U1J5.1
#=GS A0A077FI42_9RICK/46-204 AC A0A077FI42.1
#=GS A0A386HT94_9BACT/66-224 AC A0A386HT94.1
#=GS A0A1G8ZRC0_9BACT/64-218 AC A0A1G8ZRC0.1
#=GS A0A1H8HXY2_9BACT/685-836 AC A0A1H8HXY2.1
#=GS A0A024FLG8_9FLAO/40-183 AC A0A024FLG8.1
#=GS A0A0N0K6J9_9SPHN/57-215 AC A0A0N0K6J9.1
#=GS A0A1H5SJJ5_9BACT/88-248 AC A0A1H5SJJ5.1
#=GS A0A7K0G4J3_9SPHI/73-222 AC A0A7K0G4J3.1
#=GS A0A2P8HRX2_CHINA/92-259 AC A0A2P8HRX2.1
#=GS A0A167KF62_9FLAO/73-239 AC A0A167KF62.1
#=GS A3XKN7_LEEBM/61-229 AC A3XKN7.1
#=GS Q5GZS2_XANOR/54-223 AC Q5GZS2.1
#=GS A0A4Y9QWH2_9BACT/63-221 AC A0A4Y9QWH2.1
#=GS G8TEF8_NIAKG/60-220 AC G8TEF8.1
#=GS A0A372IUQ6_9BACT/62-221 AC A0A372IUQ6.1
#=GS A0A3N6PYT1_9BURK/59-226 AC A0A3N6PYT1.1
#=GS A0A364Y4D6_9BACT/61-231 AC A0A364Y4D6.1
#=GS W2CK66_9BACT/40-210 AC W2CK66.1
#=GS A0A399CWH7_9BACT/68-231 AC A0A399CWH7.1
#=GS A0A5C6YDQ4_9FLAO/64-219 AC A0A5C6YDQ4.1
#=GS A0A1Q6A4C7_9SPHI/62-226 AC A0A1Q6A4C7.1
#=GS S8GYD8_9BACT/38-202 AC S8GYD8.1
#=GS A0A426K7J9_9FLAO/61-220 AC A0A426K7J9.1
#=GS A6CEA7_9PLAN/67-222 AC A6CEA7.1
#=GS A0A1Q6A519_9SPHI/688-836 AC A0A1Q6A519.1
#=GS A0A069NV49_9BURK/30-199 AC A0A069NV49.1
#=GS A0A7Y9C6Z0_9FLAO/52-209 AC A0A7Y9C6Z0.1
#=GS A0A2S7WPY9_9FLAO/55-216 AC A0A2S7WPY9.1
#=GS A0A2V3PV72_9BACT/37-197 AC A0A2V3PV72.1
#=GS I3C5W0_9FLAO/67-213 AC I3C5W0.1
#=GS A0A1G9B2U1_9FLAO/53-212 AC A0A1G9B2U1.1
#=GS A0A1Q3GIT8_9BACT/54-223 AC A0A1Q3GIT8.1
#=GS A0A1W2ANL0_9BURK/52-221 AC A0A1W2ANL0.1
#=GS A0A163BUM9_9FLAO/33-185 AC A0A163BUM9.1
#=GS A0A6B3L119_9BACT/81-252 AC A0A6B3L119.1
#=GS H1YIP8_9SPHI/61-227 AC H1YIP8.1
#=GS A0A369VX83_9SPHN/64-229 AC A0A369VX83.1
#=GS A0A4S1E1L9_9FLAO/64-218 AC A0A4S1E1L9.1
#=GS A0A6I4IAX9_9SPHI/53-216 AC A0A6I4IAX9.1
#=GS A0A291QW05_9BACT/72-256 AC A0A291QW05.1
#=GS A0A2P8C7L0_9BACT/81-237 AC A0A2P8C7L0.1
#=GS A0A5B1BA33_9FLAO/56-219 AC A0A5B1BA33.1
#=GS A0A6L9EH19_9FLAO/63-226 AC A0A6L9EH19.1
#=GS A0A150AL41_9BACT/66-210 AC A0A150AL41.1
#=GS I0HR71_RUBGI/71-241 AC I0HR71.1
#=GS E8X468_GRATM/70-240 AC E8X468.1
#=GS B7J9W7_ACIF2/58-219 AC B7J9W7.1
#=GS A0A173MFJ7_9BACT/66-216 AC A0A173MFJ7.1
#=GS A0A1W6LJ20_9BACT/58-233 AC A0A1W6LJ20.1
#=GS A0A841ERS4_9BACT/52-217 AC A0A841ERS4.1
#=GS A0A4R5CHE9_9FLAO/67-227 AC A0A4R5CHE9.1
#=GS A0A5S5DLM6_9SPHI/2-153 AC A0A5S5DLM6.1
#=GS A0A1H1L3E3_9FLAO/65-225 AC A0A1H1L3E3.1
#=GS A0A1W6LJ20_9BACT/669-846 AC A0A1W6LJ20.1
#=GS A0A1I4TPZ5_9FLAO/59-217 AC A0A1I4TPZ5.1
#=GS A0A1N6KJ31_9BURK/42-209 AC A0A1N6KJ31.1
#=GS A0A5B9EHS5_9BACT/71-230 AC A0A5B9EHS5.1
#=GS A0A6M0CLJ7_9FLAO/50-213 AC A0A6M0CLJ7.1
#=GS A0A0A2MPH5_9FLAO/63-225 AC A0A0A2MPH5.1
#=GS R5NSF1_9BACT/36-194 AC R5NSF1.1
#=GS A0A2G5L5T6_9BACT/67-244 AC A0A2G5L5T6.1
#=GS A0A7H0VHN7_9FLAO/53-219 AC A0A7H0VHN7.1
#=GS A0A7D3X512_9BACT/83-229 AC A0A7D3X512.1
#=GS A0A2T5JDE1_9SPHI/741-833 AC A0A2T5JDE1.1
#=GS A0A8J7J919_9FLAO/64-218 AC A0A8J7J919.1
#=GS A0A1M5F2U0_9BACE/53-216 AC A0A1M5F2U0.1
#=GS R6FEQ7_9BACE/40-209 AC R6FEQ7.1
#=GS A0A243WE35_9BACT/57-223 AC A0A243WE35.1
#=GS A0A7D5SC45_9BACT/4-166 AC A0A7D5SC45.1
#=GS A0A4S5JDL6_9HYPH/71-240 AC A0A4S5JDL6.1
#=GS A0A1T5P6J8_9BACT/60-226 AC A0A1T5P6J8.1
#=GS A0A4Q7PGL3_9FLAO/80-247 AC A0A4Q7PGL3.1
#=GS A0A7K0FX10_9SPHI/65-235 AC A0A7K0FX10.1
#=GS A0A2N4X7D1_9BACT/81-238 AC A0A2N4X7D1.1
#=GS A6GH78_9DELT/138-305 AC A6GH78.1
#=GS A0A3M9NC81_9BACT/55-213 AC A0A3M9NC81.1
#=GS A0A1G9G4K7_9SPHI/54-216 AC A0A1G9G4K7.1
#=GS A0A516GN87_9FLAO/65-216 AC A0A516GN87.1
#=GS A0A5C7GJR8_9FLAO/53-216 AC A0A5C7GJR8.1
#=GS A0A1B6YA61_9BACT/67-237 AC A0A1B6YA61.1
#=GS A0A0F4QH05_9GAMM/73-240 AC A0A0F4QH05.1
#=GS A0A0M2XSG5_9SPHI/67-232 AC A0A0M2XSG5.1
#=GS A0A7W2FXJ8_9FLAO/61-220 AC A0A7W2FXJ8.1
#=GS A0A365NZQ3_9FLAO/65-224 AC A0A365NZQ3.1
#=GS A0A519IXJ0_9CAUL/63-232 AC A0A519IXJ0.1
#=GS A0A8J7IF10_9FLAO/65-219 AC A0A8J7IF10.1
#=GS A0A2P7TCH3_9SPHI/76-226 AC A0A2P7TCH3.1
#=GS A0A1M5DQ37_9FLAO/66-227 AC A0A1M5DQ37.1
#=GS A4AR94_MARSH/65-219 AC A4AR94.1
#=GS A0A1D8P7M0_9FLAO/64-231 AC A0A1D8P7M0.1
#=GS A0A4R3VHX7_PELSC/45-213 AC A0A4R3VHX7.1
#=GS A0A238W9H1_9FLAO/66-218 AC A0A238W9H1.1
#=GS A0A5C6YD62_9FLAO/75-224 AC A0A5C6YD62.1
#=GS A0A6I4U4C8_9SPHN/71-235 AC A0A6I4U4C8.1
#=GS A0A5D6V290_9BACT/75-231 AC A0A5D6V290.1
#=GS A0A1T5CEZ4_9BACT/53-216 AC A0A1T5CEZ4.1
#=GS A0A167EZL2_9FLAO/66-218 AC A0A167EZL2.1
#=GS F0S2H7_DESTD/37-206 AC F0S2H7.1
#=GS A0A562U2G1_9SPHI/68-217 AC A0A562U2G1.1
#=GS A0A146G731_TERSA/71-241 AC A0A146G731.1
#=GS A0A1N6UPH2_9BACT/73-240 AC A0A1N6UPH2.1
#=GS A0A4R6IED2_9SPHI/73-242 AC A0A4R6IED2.1
#=GS A0A7W2FZJ0_9FLAO/44-205 AC A0A7W2FZJ0.1
#=GS A0A2R7L6T7_9FLAO/52-213 AC A0A2R7L6T7.1
#=GS A0A1T4PHC5_9BACT/739-833 AC A0A1T4PHC5.1
#=GS A0A1H8FD84_9BACT/66-257 AC A0A1H8FD84.1
#=GS A0A0N7HWC8_9BACT/48-218 AC A0A0N7HWC8.1
#=GS R6DM20_9BACE/54-235 AC R6DM20.1
#=GS A0A5C0ZII0_9SPHI/53-216 AC A0A5C0ZII0.1
#=GS A0A254N135_9BURK/78-245 AC A0A254N135.1
#=GS H8MPA6_CORCM/79-246 AC H8MPA6.1
#=GS A0A1D7QB31_9SPHI/54-216 AC A0A1D7QB31.1
#=GS A0A1H3ZMS5_9FLAO/52-210 AC A0A1H3ZMS5.1
#=GS A0A367GVP6_9SPHI/61-221 AC A0A367GVP6.1
#=GS A0A553G189_9BACT/58-221 AC A0A553G189.1
#=GS F2IEH9_FLUTR/66-228 AC F2IEH9.1
#=GS A0A4U1JBH9_9DELT/677-846 AC A0A4U1JBH9.1
#=GS A0A7K3WKQ5_9FLAO/83-257 AC A0A7K3WKQ5.1
#=GS A0A103ECG0_9BURK/77-238 AC A0A103ECG0.1
#=GS A0A2R4C9Q7_9BURK/73-234 AC A0A2R4C9Q7.1
#=GS A0A1H0P280_9HYPH/43-210 AC A0A1H0P280.1
#=GS A0A291QQR2_9BACT/89-262 AC A0A291QQR2.1
#=GS U5QB18_9BACT/69-242 AC U5QB18.1
#=GS Q5H2P8_XANOR/1-139 AC Q5H2P8.1
#=GS A0A8J6TTF4_9FLAO/57-223 AC A0A8J6TTF4.1
#=GS A0A8J8FAG4_9BACT/90-255 AC A0A8J8FAG4.1
#=GS C6XAB6_METGS/87-254 AC C6XAB6.1
#=GS A0A161L9E4_9BACT/64-215 AC A0A161L9E4.1
#=GS F8X301_9BACT/38-196 AC F8X301.1
#=GS A0A6M0CTM2_9FLAO/62-223 AC A0A6M0CTM2.1
#=GS A0A0N1BEJ8_9SPHN/7-162 AC A0A0N1BEJ8.1
#=GS A0A1H9HU94_9BACT/51-215 AC A0A1H9HU94.1
#=GS A0A2G8TII9_9BURK/75-244 AC A0A2G8TII9.1
#=GS A0A5C6ZGI1_9FLAO/69-238 AC A0A5C6ZGI1.1
#=GS A0A2H3NJG1_9BACT/71-241 AC A0A2H3NJG1.1
#=GS A0A1M4VYK4_9FLAO/67-236 AC A0A1M4VYK4.1
#=GS A0A1V1PJP6_9PROT/60-226 AC A0A1V1PJP6.1
#=GS A0A2T3HIB0_9SPHI/51-214 AC A0A2T3HIB0.1
#=GS A0A1Y0NCU0_9BURK/78-245 AC A0A1Y0NCU0.1
#=GS A0A2S7T711_9FLAO/51-206 AC A0A2S7T711.1
#=GS A0A5C8ZBF3_9GAMM/64-221 AC A0A5C8ZBF3.1
#=GS A0A1M4SJQ0_9FLAO/62-222 AC A0A1M4SJQ0.1
#=GS A0A4R1RC94_9FLAO/64-217 AC A0A4R1RC94.1
#=GS A0A0C5VT93_9GAMM/64-233 AC A0A0C5VT93.1
#=GS A0A3D8JY40_9BURK/30-199 AC A0A3D8JY40.1
#=GS A0A1P8RZ41_9FLAO/66-222 AC A0A1P8RZ41.1
#=GS A0A1M5LJE2_9FLAO/61-226 AC A0A1M5LJE2.1
#=GS A0A315YY74_9BACT/84-250 AC A0A315YY74.1
#=GS A0A1I2LB82_9BACT/55-217 AC A0A1I2LB82.1
#=GS A0A1H1Q2D5_9FLAO/65-218 AC A0A1H1Q2D5.1
#=GS A0A7X0UW40_9GAMM/63-229 AC A0A7X0UW40.1
#=GS A0A2N4X7D6_9BACT/84-255 AC A0A2N4X7D6.1
#=GS A0A1H7LN80_9GAMM/68-234 AC A0A1H7LN80.1
#=GS A0A158ITZ5_9BURK/49-213 AC A0A158ITZ5.1
#=GS A0A2S9XLX0_9DELT/738-903 AC A0A2S9XLX0.1
#=GS A0A4Y9RH01_9CAUL/1-133 AC A0A4Y9RH01.1
#=GS A0A1G7P643_9BACT/53-221 AC A0A1G7P643.1
#=GS A0A4V2VU97_9SPHI/63-230 AC A0A4V2VU97.1
#=GS A0A4Q0T0N0_9BACT/35-194 AC A0A4Q0T0N0.1
#=GS A0A386HRM0_9BACT/59-218 AC A0A386HRM0.1
#=GS A0A1C2GHE1_9SPHI/133-270 AC A0A1C2GHE1.1
#=GS A0A1Q3GIU5_9BACT/65-217 AC A0A1Q3GIU5.1
#=GS A0A2D1U3P2_9SPHI/74-242 AC A0A2D1U3P2.1
#=GS A0A1W7MC30_9SPHN/62-230 AC A0A1W7MC30.1
#=GS B2JCI2_PARP8/53-220 AC B2JCI2.1
#=GS A0A220W9I6_9SPHN/62-228 AC A0A220W9I6.1
#=GS A0A3S9NY08_9BACT/72-244 AC A0A3S9NY08.1
#=GS E5CEG2_9BACE/72-256 AC E5CEG2.1
#=GS A0A327QUA0_9BACT/60-221 AC A0A327QUA0.1
#=GS A0A364XYK6_9BACT/64-220 AC A0A364XYK6.1
#=GS A0A5N1J7J8_9BACT/73-243 AC A0A5N1J7J8.1
#=GS A0A4U0NKR4_9SPHI/54-216 AC A0A4U0NKR4.1
#=GS F8L013_PARAV/67-234 AC F8L013.1
#=GS A0A172UD52_9GAMM/78-228 AC A0A172UD52.1
#=GS A0A172TWK1_9BACT/68-235 AC A0A172TWK1.1
#=GS A0A1M5R3Q8_9BACT/57-211 AC A0A1M5R3Q8.1
#=GS A0A086F2P6_CHRP1/62-231 AC A0A086F2P6.1
#=GS A0A199XV38_9FLAO/53-217 AC A0A199XV38.1
#=GS A0A5S3Q635_9FLAO/17-176 AC A0A5S3Q635.1
#=GS A6ER88_9BACT/48-211 AC A6ER88.1
#=GS A0A372K5N3_9BURK/46-210 AC A0A372K5N3.1
#=GS A0A5B7SPW8_9FLAO/51-216 AC A0A5B7SPW8.1
#=GS A0A0U3SBV6_9BACT/66-221 AC A0A0U3SBV6.1
#=GS A0A4Z0L4L3_9FLAO/52-216 AC A0A4Z0L4L3.1
#=GS A0A495J764_9SPHI/62-227 AC A0A495J764.1
#=GS A0A4R5CAH3_9FLAO/68-226 AC A0A4R5CAH3.1
#=GS A0A4V3AUS6_9BURK/67-227 AC A0A4V3AUS6.1
#=GS G8UKI5_TANFA/36-205 AC G8UKI5.1
#=GS A0A2S7WE55_9FLAO/53-215 AC A0A2S7WE55.1
#=GS A0A653XHJ2_9FLAO/62-230 AC A0A653XHJ2.1
#=GS A0A0P0M8A9_9BURK/48-217 AC A0A0P0M8A9.1
#=GS A0A848FXE2_9BACT/57-219 AC A0A848FXE2.1
#=GS A0A8J8GAH1_9FLAO/50-211 AC A0A8J8GAH1.1
#=GS A0A149PY20_9BURK/45-210 AC A0A149PY20.1
#=GS A0A0Q4BM49_9SPHN/23-187 AC A0A0Q4BM49.1
#=GS A0A4Q7N5P0_9BACT/59-222 AC A0A4Q7N5P0.1
#=GS A0A255Y5Z4_9SPHN/73-242 AC A0A255Y5Z4.1
#=GS R6E580_9BACE/40-209 AC R6E580.1
#=GS A0A2U8E4E6_9BACT/80-236 AC A0A2U8E4E6.1
#=GS C5BPE2_TERTT/21-200 AC C5BPE2.1
#=GS A0A2V4A015_9BACT/64-218 AC A0A2V4A015.1
#=GS A0A8J3BCK3_9FLAO/63-222 AC A0A8J3BCK3.1
#=GS L8JEM8_9GAMM/66-227 AC L8JEM8.1
#=GS A0A3N4QCK3_9BACT/65-230 AC A0A3N4QCK3.1
#=GS A0A845B1H0_9SPHN/61-227 AC A0A845B1H0.1
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