GenomeNet

Database: Pfam
Entry: KAAG1
LinkDB: KAAG1
Original site: KAAG1 
#=GF ID   KAAG1
#=GF AC   PF15354.1
#=GF DE   Kidney-associated antigen 1
#=GF AU   Coggill P
#=GF SE   Jackhmmer:Q9UBP8
#=GF GA   27.00 27.00;
#=GF TC   88.30 88.30;
#=GF NC   25.00 19.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   10601354
#=GF RT   A new antigen recognized by cytolytic T lymphocytes on a human
#=GF RT   kidney tumor results from reverse strand transcription.
#=GF RA   Van Den Eynde BJ, Gaugler B, Probst-Kepper M, Michaux L, Devuyst
#=GF RA   O, Lorge F, Weynants P, Boon T;
#=GF RL   J Exp Med. 1999;190:1793-1800.
#=GF CC   KAAG1, kidney-associated antigen 1, or RU2AS (RU2 antisense gene
#=GF CC   protein) has been found in mammals. It is expressed in testis
#=GF CC   and kidney, and, at lower levels, in urinary bladder and liver.
#=GF CC   It is expressed by a high proportion of tumours of various
#=GF CC   histologic origin, including melanomas, sarcomas and colorectal
#=GF CC   carcinomas.
#=GF SQ   9
#=GS F7DG90_MACMU/1-84  AC F7DG90.1
#=GS H2QSD4_PANTR/1-84  AC H2QSD4.1
#=GS H2PI23_PONAB/1-84  AC H2PI23.1
#=GS F1RUF3_PIG/1-48    AC F1RUF3.1
#=GS G7P4J2_MACFA/1-84  AC G7P4J2.1
#=GS KAAG1_HUMAN/1-84   AC Q9UBP8.1
#=GS G1SAM1_NOMLE/1-84  AC G1SAM1.1
#=GS G3T1J2_LOXAF/1-83  AC G3T1J2.1
#=GS F7IKT1_CALJA/1-81  AC F7IKT1.1
F7DG90_MACMU/1-84             MDDDAAPREEGVPVAVHKHALHDGLRQVAGPGAAATHLPRWPQPQLAAPRREAPPLPQRPHSTQGAGSPPETNEKLTNPQVK--rs
H2QSD4_PANTR/1-84             MDDDAAPRVEGVPVAVHKHALHDGLRQVAGPGAAAAHLPRWPPPQLAASRREAPPLSQRPHRTQGAGSPPETNEKLTNPQVKEK..
H2PI23_PONAB/1-84             MDDDAAPRVEGVPVAVHKHALHDGLRQVAGPGAAAAHLPRWPPPQLAASRREATPLSQRPHRTQGAGSPPETNEKLTNPQVKEK..
F1RUF3_PIG/1-48               VDDNAAPREEGVPVAVHQHALHDRLRQVAGPGAGAAHLPHGTPPRLA-------------------------------------s.
G7P4J2_MACFA/1-84             MDDDAAPREEGVPVAVHKHALHDGLRQVAGPGAAATHLPRWPQPQLAAPRREAPPLPQRPHSTQGAGSPPETNEKLTNPQVK--rs
KAAG1_HUMAN/1-84              MDDDAAPRVEGVPVAVHKHALHDGLRQVAGPGAAAAHLPRWPPPQLAASRREAPPLSQRPHRTQGAGSPPETNEKLTNPQVKEK..
G1SAM1_NOMLE/1-84             MDDDAAPRVEGVPVAVHKHALHDGLRQVAGPGAAAAHLPRWPPPQLAASRREAPPLSQRPHRTQGAGSPPETNEKLTNPQVKEK..
G3T1J2_LOXAF/1-83             MDDDAAPCEEGVPVAVHQHALHYRLRQVVGPGAGAVHLPRGTPRRLAAP-GVAPLLSQLPHRTHGAGSSPETNGQETNPKVREK..
F7IKT1_CALJA/1-81             MDDDAAPREVGVPVAVHQHALHHGLRQVAGPGAAAAHLPRSPPP--AARRGEAPPLPRRSRRTQGAGSPPETNEKLTNPQVK--k.
#=GC seq_cons                 MDDDAAPR.EGVPVAVHKHALHDGLRQVAGPGAAAAHLPRWPPPQLAAsRREAPPLsQRPHRTQGAGSPPETNEKLTNPQVK....
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