#=GF ID   KAAG1
#=GF AC   PF15354.10
#=GF DE   Kidney-associated antigen 1
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   Jackhmmer:Q9UBP8
#=GF GA   27.00 27.00;
#=GF TC   28.30 27.90;
#=GF NC   25.10 23.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   10601354
#=GF RT   A new antigen recognized by cytolytic T lymphocytes on a human
#=GF RT   kidney tumor results from reverse strand transcription.
#=GF RA   Van Den Eynde BJ, Gaugler B, Probst-Kepper M, Michaux L, Devuyst
#=GF RA   O, Lorge F, Weynants P, Boon T;
#=GF RL   J Exp Med. 1999;190:1793-1800.
#=GF DR   INTERPRO; IPR029407;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   KAAG1, kidney-associated antigen 1, or RU2AS (RU2 antisense gene
#=GF CC   protein) has been found in mammals. It is expressed in testis
#=GF CC   and kidney, and, at lower levels, in urinary bladder and liver.
#=GF CC   It is expressed by a high proportion of tumours of various
#=GF CC   histologic origin, including melanomas, sarcomas and colorectal
#=GF CC   carcinomas.
#=GF SQ   44
#=GS A0A8C5T912_9PASS/1-61    AC A0A8C5T912.1
#=GS A0A8C3XGF0_9PASS/36-102  AC A0A8C3XGF0.1
#=GS H2PI23_PONAB/1-84        AC H2PI23.1
#=GS A0A5F7Z6X7_MACMU/1-85    AC A0A5F7Z6X7.1
#=GS A0A8B9QJ81_APTOW/1-62    AC A0A8B9QJ81.1
#=GS A0A8C9GKY5_9PRIM/1-84    AC A0A8C9GKY5.1
#=GS A0A5N3VZE0_MUNRE/1-84    AC A0A5N3VZE0.1
#=GS A0A8M1H0Z8_URSMA/1-82    AC A0A8M1H0Z8.1
#=GS A0A2R8ZL66_PANPA/1-84    AC A0A2R8ZL66.1
#=GS A0A3Q0CL65_MESAU/1-80    AC A0A3Q0CL65.1
#=GS A0A803V3P9_FICAL/1-69    AC A0A803V3P9.1
#=GS A0A2K5F2R3_AOTNA/1-78    AC A0A2K5F2R3.1
#=GS A0A8C8VGT4_9SAUR/1-70    AC A0A8C8VGT4.1
#=GS A0A8C9DJF6_PROSS/1-83    AC A0A8C9DJF6.1
#=GS A0A8C8BME3_9STRI/36-108  AC A0A8C8BME3.1
#=GS A0A3Q1LIT1_BOVIN/1-84    AC A0A3Q1LIT1.1
#=GS A0A673U7B3_SURSU/1-82    AC A0A673U7B3.1
#=GS A0A8C4XLA9_FALTI/36-123  AC A0A8C4XLA9.1
#=GS A0A8D2M9X0_ZONAL/36-99   AC A0A8D2M9X0.1
#=GS A0A663FCN2_AQUCH/36-114  AC A0A663FCN2.1
#=GS A0A8C3TST3_CATUS/36-145  AC A0A8C3TST3.1
#=GS A0A8C6ICI9_MUSSI/1-77    AC A0A8C6ICI9.1
#=GS A0A8I3S2Z6_CANLF/1-79    AC A0A8I3S2Z6.1
#=GS A0A7N9CKJ8_MACFA/1-85    AC A0A7N9CKJ8.1
#=GS A0A0D9SCM4_CHLSB/1-82    AC A0A0D9SCM4.1
#=GS A0A8C5YM20_MARMA/1-81    AC A0A8C5YM20.1
#=GS A0A8U8AX09_GEOPR/36-105  AC A0A8U8AX09.1
#=GS A0A8C0HP64_9AVES/36-121  AC A0A8C0HP64.1
#=GS A0A8I5N5S2_PAPAN/1-85    AC A0A8I5N5S2.1
#=GS L8I627_9CETA/1-80        AC L8I627.1
#=GS A0A8C2X0A3_CYCLU/1-63    AC A0A8C2X0A3.1
#=GS G3T1J2_LOXAF/1-83        AC G3T1J2.1
#=GS A0A8B9LYE7_9AVES/36-91   AC A0A8B9LYE7.1
#=GS A0A8C5NRW3_JUNHY/36-99   AC A0A8C5NRW3.1
#=GS A0A7N5P643_AILME/1-82    AC A0A7N5P643.1
#=GS A0A8B7TVE6_CASCN/1-79    AC A0A8B7TVE6.1
#=GS A0A2I3RC57_PANTR/1-84    AC A0A2I3RC57.1
#=GS KAAG1_HUMAN/1-84         AC Q9UBP8.1
#=GS A0A2I3GBI8_NOMLE/1-84    AC A0A2I3GBI8.1
#=GS A0A8D2FQ55_THEGE/1-84    AC A0A8D2FQ55.1
#=GS A0A8C0KB24_CANLU/1-76    AC A0A8C0KB24.1
#=GS A0A4W2E5Q1_BOBOX/1-83    AC A0A4W2E5Q1.1
#=GS A0A3Q2KPV0_HORSE/1-78    AC A0A3Q2KPV0.1
#=GS A0A8C4LU98_EQUAS/1-78    AC A0A8C4LU98.1
A0A8C5T912_9PASS/1-61               .MDDNAASREERVPVAIHQHALHGGLRE....PRP...LRARTAHA-...-..-.-.---......--......----.----..---.---.-----------------------ggfarpaqpepalraactcpepl............................
A0A8C3XGF0_9PASS/36-102             .VDDYAAPREERVPVAIHQHALHGRLRE....PRR...LCARTRHAA...G..S.V.RPA......L-......----.----..---.---.-----------------------peppappenlreskthvpsiq..............................
H2PI23_PONAB/1-84                   .MDDDAAPRVEGVPVAVHKHALHDGLRQ....VAG...PGAAAAHLP...R..W.P.PPQ......LA......ASRR.EATP..LSQ.RPH.RTQGAGSPPETNEKLTNPQVKEK...................................................
A0A5F7Z6X7_MACMU/1-85               .MDDDAAPREEGVPVAVHKHALHDGLRQ....VAG...PGAAATHLP...R..W.P.QPQ......LA......APRR.EAPP..LPQ.RPH.STQGAGSPPETNEKLTNPQT---lsek...............................................
A0A8B9QJ81_APTOW/1-62               .IDDNAAPREEGVPVAVHQHALHHRLRE....ARP...LSAQTTH-A...R..Q.P.QTS......CA......AK-A.VA--..---.---.-----------------------gqrlhlfmqet........................................
A0A8C9GKY5_9PRIM/1-84               .MDDDAAPREEGVPVAVHKHALHDGLRQ....VAG...PGATAAHLP...R..W.P.PPH......LA......APRR.EAPL..LPQ.RPQ.CTQGAGSPPETNEKLTNPQS---ekg................................................
A0A5N3VZE0_MUNRE/1-84               v-EDDAAAREEGVPVAVHQHALHDRLRQ....VPG...PGTGATHLP...L..G.T.PAR......LA......SPGGgTAAA..PAA.SPH.-TRGAGSRPETNAKQTSPRA---tar................................................
A0A8M1H0Z8_URSMA/1-82               .MDDDAASREEGVPVAVYEHALHDRLGQ....VAG...PGACAAHLP...R..G.T.PPC......WL......LG-G.-GAS..AAQ.LPH.RTHPAGSPPETNAKQTSPRLKKK...................................................
A0A2R8ZL66_PANPA/1-84               .MDDDAAPRVEGVPVAVHKHALHDGLRQ....VAG...PGAAAAHLP...R..W.P.PPQ......LA......ASRR.EAPP..LSQ.RPH.RTQGAGSPPETNEKLTNPQVKEK...................................................
A0A3Q0CL65_MESAU/1-80               .MNDNTAPGEEGVPIAVHQYALHYWLRQ....VVG...PGARAVHLP...F..W.T.PGP......LA......LHGP.ATPV..RGP.PPA.ET---------------------rkghsqvkkcqpcgasp..................................
A0A803V3P9_FICAL/1-69               .VDDDAAPREERVPVAIHQHALHGRLRE....PGR...LGAGTSHAAgsvR..S.A.PAG......RA......EG-R.GAPT..A--.---.-----------------------lrhtlrtgsrn........................................
A0A2K5F2R3_AOTNA/1-78               .MDDDAAPREKGVPVAVHQHALHHGLRQ....VAG...PGAAAAHLP...R..S.P.---......LA......---R.EAPP..LPG.RPQ.RTQGAGSPPETNEKLTNPQVKEK...................................................
A0A8C8VGT4_9SAUR/1-70               .MDEHPVPREELVPIAVHQHALHHRLRQ....ERQ...LCARATHVP...P..R.T.AAA......TA......----.----..---.---.-----------------------gqlvlptkgreapvqtgdkgnsr............................
A0A8C9DJF6_PROSS/1-83               l-EDDAAPREEGVPVAVHQHALDDRLRQ....VAG...PGAGAAHLP...R..G.T.LPQ......LA......S-RG.DAPP..LPG.RPR.RTHSAGSPPETNGKLTDPRGREK...................................................
A0A8C8BME3_9STRI/36-108             .IDDNTAPREERVPVAIHHHALHRRLRD....APGlpaTGQGPAELP...R..G.A.GGR......ET......RGRR.RAPN..SQQgRPG.R----------------------ggqgeve............................................
A0A3Q1LIT1_BOVIN/1-84               v-EDDTAAREEGVPVAVHQHALHDRLRQ....VPG...PGTGATHLP...L..G.T.PAR......LA......SPGG.GTAA..APA.ASQ.HTRGAGSRPETTAKQTSPQKR--ri.................................................
A0A673U7B3_SURSU/1-82               .MEDDAAAREEGVPVAVHQHALHDWLGQ....VAG...PGAGAAHLP...R..G.T.PLG......WL......LG--.GGAS..AAP.RPH.GTHPVGSLAATYAKQASP-----flfae..............................................
A0A8C4XLA9_FALTI/36-123             .VDDNTAPWEERVPVAVHQHALHDRLRE....PRP...LHARVSH--...-..-.-.---......--......----.----..---.---.-----------------------agglrgswaalglptpwlgedswreapalpppprrprqraglpatregpae
A0A8D2M9X0_ZONAL/36-99              .VDDNAAPREEGVPVAIHQHALHARLREprrlCAR...AGHAAGSVR...P..V.P.PQP......LS......GPVS.GSPE..VT-.---.--Q--------------------ga.................................................
A0A663FCN2_AQUCH/36-114             .VDDNTTPREERVPVAIHQHALHHRLRE....PRP...LGASAGHAR...RpsD.P.PAQpqppatRA......AYRR.GSPP..QGQ.---.-----------------------grpaeaggeaaag......................................
A0A8C3TST3_CATUS/36-145             .VDDDAAPREERVPVAIHQHALHGRLRE....PGR...LGAGTAHAG...A..G.S.ARP......-A......AARP.YRPA..FLG.KPP.RVC--------------------paspreparslpgpeapragargpacpegaagaegtgsqagregdpr....
A0A8C6ICI9_MUSSI/1-77               v-NDDTAPGEKGVPIAVHQHTLHHRLRQ....VAG...PGAGTVHLL...R..G.T.PSP......QAlhrpatAARG.PPPF..KSQ.QPH.G----------------------gsqpplmrs..........................................
A0A8I3S2Z6_CANLF/1-79               .VDDHAAPREERVPVAVHQHALHDRLGQ....VAG...PGAGAAHPP...R..G.D.APG......GL......-LRG.RAAA..AGG.LPR.APAGSCLKPTRNRQ---------argkk..............................................
A0A7N9CKJ8_MACFA/1-85               .MDDDAAPREEGVPVAVHEHALHDGLRQ....VAG...PGAAATHLP...R..W.P.QPQ......LA......APRR.EAPP..LPQ.RPH.STQGAGSPPETNEKLTNPQT---lsek...............................................
A0A0D9SCM4_CHLSB/1-82               .MDDDAAPCEEGVPVAVHKHALHDGLRQ....VAG...PGAAAAHLP...R..W.P.PPQ......LA......APRR.EAPP..LPQ.RPH.STQGAGSPPETNEKLTNPQVK--...................................................
A0A8C5YM20_MARMA/1-81               .MDDHAASREERVPVAIHQHALHHRLGQ....VAG...PGAAAAHFP...A..G.RlPSW......LQ......AE--.-ARS..LPP.RPP.R-RGGGKMPEKLGKPS-------sqgteek............................................
A0A8U8AX09_GEOPR/36-105             .VDDNAAPREERVPVAIHQHALHARLRE....PRR...LCARAGHAA...-..-.-.---......--......----.----..---.---.-----------------------grascaapaartwgrgyrgngisrgrqgnpr....................
A0A8C0HP64_9AVES/36-121             .VDDNTTPREERVPVAIHQHALHHRLRE....PRP...LGASAAPLS...P..P.P.SRR......GA......DEGP.THPRrgLGS.RAH.LRGGRGGSPAPRGGIT-------ttpgeek............................................
A0A8I5N5S2_PAPAN/1-85               .MDDDAAPRKEGVPVAVHKHALHDGLRQ....VAG...PGAAAAHLP...R..W.P.QPQ......LA......APRR.EAPP..LPQ.RPH.STQGAGSPPETNEKLTNPQT---lsek...............................................
L8I627_9CETA/1-80                   v-EDDTAAREEGVPVAVHQHALHDRLRQ....VPG...PGTGATHLP...L..G.T.PAR......LA......SPGG.GTAA..APA.ASQ.HTRGAGSRPETNAKQTSPR----...................................................
A0A8C2X0A3_CYCLU/1-63               .VDDNAAGIVVRVAVSVHKHVLHDRLRQ....KVW...---------...-..-.-.---......--......----.----..---.---.-----------------------llrahrclicwdvsmgtrrcsltdyqrphkavi..................
G3T1J2_LOXAF/1-83                   .MDDDAAPCEEGVPVAVHQHALHYRLRQ....VVG...PGAGAVHLP...R..G.T.PRR......LA......AP-G.VAPL..LSQ.LPH.RTHGAGSSPETNGQETNPKVREK...................................................
A0A8B9LYE7_9AVES/36-91              .VDDNTAPREERVPVAIHQHALHHRLRE....QVPa.lPPPPPRRPR...R..S.L.PPG......LP......AT--.----..---.---.-----------------------rerpa..............................................
A0A8C5NRW3_JUNHY/36-99              .VDDNAASREEGVPVAIHQHALHARLREprrlCAR...AGHAAGSVR...P..V.P.PQP......LS......GPVS.GSPE..VT-.---.--Q--------------------ga.................................................
A0A7N5P643_AILME/1-82               .MDDDAASREEGVPVAVYKHALHDRLGQ....VAG...PGACAAHLP...R..G.T.PPC......WL......LG-G.-GAS..AAQ.LPH.RTHPARSPAETNAKQTSPRLKKK...................................................
A0A8B7TVE6_CASCN/1-79               .MDDDSAPREEGVPIAVHQHALHDRLGQ....VTG...PGTGTAHRP...R..G.T.PPL......LD......SQ-G.QAPA..LPG.WPH.GTHGXGSPPARNGKR--------qthe...............................................
A0A2I3RC57_PANTR/1-84               .MDDDAAPRVEGVPVAVHKHALHDGLRQ....VAG...PGAAAAHLP...R..W.P.PPQ......LA......ASRR.EAPP..LSQ.RPH.RTQGAGSPPETNEKLTNPQVKEK...................................................
KAAG1_HUMAN/1-84                    .MDDDAAPRVEGVPVAVHKHALHDGLRQ....VAG...PGAAAAHLP...R..W.P.PPQ......LA......ASRR.EAPP..LSQ.RPH.RTQGAGSPPETNEKLTNPQVKEK...................................................
A0A2I3GBI8_NOMLE/1-84               .MDDDAAPRVEGVPVAVHKHALHDGLRQ....VAG...PGAAAAHLP...R..W.P.PPQ......LA......ASRR.EAPP..LSQ.RPH.RTQGAGSPPETNEKLTNPQVKEK...................................................
A0A8D2FQ55_THEGE/1-84               .MDDDAAPREEGVPVAVHKHALHDGLRQ....VAG...PGAAAAHLP...R..W.P.QPQ......LA......APRW.EAPP..LPQ.RPH.STQGAGSPPETNEKLTNPQVKRK...................................................
A0A8C0KB24_CANLU/1-76               .VDDHAAPREERVPVAVHQHALHDRLGQ....VAG...PGAGAAHPP...R..GdA.PGG......LL......RGRA.AAAG..GQA.RPYaRTQGKDA----------------papllt.............................................
A0A4W2E5Q1_BOBOX/1-83               v-EDDTAAREEGVPVAVHQHALHDRLRQ....VPG...PGTGATHLP...L..G.T.PAR......LA......SPGG.GTAA..APA.ASQ.HTRGAGSRPETNAKQTSPE----kps................................................
A0A3Q2KPV0_HORSE/1-78               .MDDDAAPREERVPVAVHQHALHDRLRQ....VAG...PGAGAAHLP...H..G.T.PGR......LA......SQ-G.EAPR..LRQ.RPH.RTHSAGLP---------------lkrrpnrqth.........................................
A0A8C4LU98_EQUAS/1-78               .MDDDAAPREERVPVAVHQHALHDRLRQ....VAG...PGAGAAHLP...H..G.T.PGR......LA......SQ-G.EAPR..LRQ.RPH.RTHSAGSPL--------------krrpnrqth..........................................
#=GC seq_cons                       .hDDDAAPREEGVPVAVHQHALHcRLRQ....VsG...PGAuAuHLP...+..h.s.Pst......LA......us.t.tuss..hst.hPp.tsps.s..................t.................................................
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