#=GF ID   Peptidase_C71
#=GF AC   PF12386.12
#=GF DE   Pseudomurein endo-isopeptidase Pei
#=GF AU   Coggill P;0000-0001-5731-1588
#=GF SE   MEROPS_C71.001
#=GF GA   22.00 22.00;
#=GF TC   22.10 22.10;
#=GF NC   21.80 21.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -E 1000 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF CL   CL0125
#=GF RN   [1]
#=GF RM   11934493
#=GF RT   Pseudomurein endoisopeptidases PeiW and PeiP, two moderately
#=GF RT   related members of a novel family of proteases produced in
#=GF RT   Methanothermobacter strains.
#=GF RA   Luo Y, Pfister P, Leisinger T, Wasserfallen A;
#=GF RL   FEMS Microbiol Lett. 2002;208:47-51.
#=GF DR   INTERPRO; IPR022119;
#=GF DR   MEROPS; C71;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This peptidase has the catalytic triad C-H-D at the C-terminal
#=GF CC   end, a triad similar to that in thiol proteases and animal
#=GF CC   transglutaminases. It catalyses the in vitro lysis of M.
#=GF CC   marburgensis cells under reducing conditions and exhibits
#=GF CC   characteristics of metal-activated peptidases.
#=GF SQ   11
#=GS A0A370APN9_9SPIO/161-283  AC A0A370APN9.1
#=GS Q77WJ4_9CAUD/157-305      AC Q77WJ4.1
#=GS A0A315XKD6_9EURY/124-242  AC A0A315XKD6.1
#=GS A0A328SH28_9EURY/83-208   AC A0A328SH28.1
#=GS A0A5Q2W3U0_9VIRU/78-213   AC A0A5Q2W3U0.1
#=GS A0A1D2WBQ5_9EURY/78-222   AC A0A1D2WBQ5.1
#=GS A0A090AJG3_9GAMM/11-96    AC A0A090AJG3.1
#=GS A0A2T3YUS1_9HYPO/776-848  AC A0A2T3YUS1.1
#=GS Q7LYX0_9CAUD/142-283      AC Q7LYX0.1
#=GS A0A1V6N290_METAZ/92-232   AC A0A1V6N290.1
#=GS A0A370AQT1_9SPIO/175-289  AC A0A370AQT1.1
A0A370APN9_9SPIO/161-283             ....................nsrecscvecr------------.----------------.....-------------------KGM.V...R.EGI..DPTSSegrRKYMRLVIKEFT......EFISSEIR.K..VR.PDAGIY.YNHSH..VR..L..S......HR..DI.I..DgfthlelESLPG..GGWGY..WDFPITIR..YARTLGVPCIGqTGKFHTSWG-------dfnslk.................................
Q77WJ4_9CAUD/157-305                 ...............................PPVPEEVREMRR.VLGEFKTATQLYTLVS.....RRCKYKFYYNDQTPNREALKKM.V...T.DGI..NCTDA...CQLFKPVIEGLG......YSVRIEHV.K..VR.CNDNKW.YGHYF..LR..V..A......GK..EL.A..S.......VSLPS..ERWTV..WDYVSATK..TGRPLGAPCCS.RGIQHLGWGIVSPKHD.......................................
A0A315XKD6_9EURY/124-242             ........yndstmklfiktfnykgntidea------------.-----------LAIIA.....KKKLYSKYFNSQKTDKKTINDAsQ...G.KGS..NCVDW...GQVYYRIAKSLG......YDVQFVHV.K..CR.VSG---.TGHIR..LR..L..-......--..--.-..-.......-----..-----..--------..-----------.----------------khkkhtggnwinrdpaavadttsg...............
A0A328SH28_9EURY/83-208              ..................ttiigrlekaskt------------.---SIKTYKSLYNAFK.....-KFKYDYYANDIYNTAEELKRV.E..qG.KGL..NCTDH...AQLYMQAYKEAK......YTDPIRIV.RgvVT.CSNGKA.YGHVW..CQ..V..-......--..--.-..-.......-----..-----..--------..-----------.----------------yvdgawldvdpsaaaahgygigtlictrn..........
A0A5Q2W3U0_9VIRU/78-213              ...................nqelfektfnvq------------.----IESAQDLYAWLR.....DNVKYSYYYNDKYDNREVIEKI.K..rG.EGV..NCTDL...AQFCRPILRDLG......YECDFIRA.E..VK.CSNNKW.YGHVF..LR..I..R......GK..EY.N..D.......-----..--WVY..FDGTAVTHenFDRPLGKLICT.GGTRE-----------itinpk.................................
A0A1D2WBQ5_9EURY/78-222              .......................piktellk--------TIEKaVNGTFKTATQFYNLVK.....ANEKYDHYSNDIYPQGKALTRL.I...NnQGL..NCADF...AQIGHASIFELNkvyrtkYQVDYVHV.A..CK.SSSGQYnIGHIV..LR..V..K......GE..EF.K..D.......-----..--WTV..FDVAEAAS..GGLPIGRTMCS.LGYKVLSY--------nd.....................................
A0A090AJG3_9GAMM/11-96               .......................ivlvsgnl------------.----------------.....----------------------.-...-.---..---NA...HPLFSNTVSDLG......YNTKTSSV.L..NR.-EDNSK.YDHYL..AR..C..T......NI..KF.Q..N.......-KDSS..FGKTY..YNYVVKCS..NGRQA------.----------------sitawddrkkw............................
A0A2T3YUS1_9HYPO/776-848             .........................iyeiek------------.----------------.....----------------------.-...-.---..---DK...TNILRLIIEKLG......VDPHFRTA.K..VK.CHDDKW.HSHHF..LD..M..S......GR..EY.S..-.......-----..-----..--------..-----------.----------------iqygalgniasikqhdscyeta.................
Q7LYX0_9CAUD/142-283                 ...............................SLKGHWTTKVIE.KIGTFHDATSLYERVK.....KTCKYKYYYNDQVPNHVAVMRM.T...T.SGI..NCTDA...CQLFSKVLEEMG......YEVKIEHV.R..VK.CNDGKW.YGHYL..LR..V..G......GF..EL.K..D.......-----..--GTI..WDYVSATK..TGRPLGVPCCT.AGFQHLGWGIVGPVYD.......................................
A0A1V6N290_METAZ/92-232              ...........................wqkn----KYIIAIQK.LIGKFNNFTEFVEKLRayaktKKGLYKYYLNSRFIGTQKEISA.L...T.NGLmgNCVDW...SQLGRAVAVIMG......YK--ADYI.Q..WQ.CTN---.VTHLT..IR..I..S......GK..EF.N..K.......-PIVV..DLAAI..VDWNS---..-----------.----------------rryelgehwcsnnivsvnpgw..................
A0A370AQT1_9SPIO/175-289             ...........ncrqgmiekkmdpassqerq------------.----------------.....----------------------.-...-.---..-----...-KYMRHVIREFT......EYISSEVR.K..VR.ADAGIY.YNHSH..VR..L..ShrdiiqGF.tHL.E..L.......ESLPG..GGWGY..WDFPITIR..YARTLGVPCIGqTGKFHTSWG-------dfnslk.................................
#=GC seq_cons                        ..........................h.tpp........................hthht......p.hYphY.Ns.h.tt....ph.....s.pGl..NCsDh...sQlh+tllc-hG......Ypsphcpl.+..V+.sssspa.YuHhh..lR..l..s......Gh..-h.p..p................hsh..aDhs.hhp...sh.h........................h.thh.................................
//