#=GF ID Rep_2
#=GF AC PF01719.21
#=GF DE Plasmid replication protein
#=GF AU Bashton M;0000-0002-6847-1525
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE Pfam-B_1901 (release 4.1)
#=GF GA 25.00 25.00;
#=GF TC 25.40 25.10;
#=GF NC 23.50 22.00;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF CL CL0169
#=GF RN [1]
#=GF RM 1904536
#=GF RT Genetic analysis of a lactococcal plasmid replicon.
#=GF RA Xu FF, Pearce LE, Yu PL;
#=GF RL Mol Gen Genet 1991;227:33-39.
#=GF RN [2]
#=GF RM 2695401
#=GF RT Characterization of a cryptic plasmid from Lactobacillus
#=GF RT plantarum.
#=GF RA Bates EE, Gilbert HJ;
#=GF RL Gene 1989;85:253-258.
#=GF DR INTERPRO; IPR002631;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This family consists of various bacterial plasmid replication
#=GF CC (Rep) proteins. These proteins are essential for replication of
#=GF CC plasmids, the Rep proteins are topoisomerases that nick the
#=GF CC positive stand at the plus origin of replication and also at the
#=GF CC single-strand conversion sequence [2].
#=GF SQ 188
#=GS E1MA47_9STRE/1-201 AC E1MA47.1
#=GS A0A139N8X2_9STRE/3-186 AC A0A139N8X2.1
#=GS A0A3A9HF83_9FIRM/40-215 AC A0A3A9HF83.1
#=GS A3CR50_STRSV/1-184 AC A3CR50.1
#=GS A0A380Q0Z5_9FIRM/19-201 AC A0A380Q0Z5.1
#=GS A0A4S3B3N7_9ENTE/30-297 AC A0A4S3B3N7.1
#=GS A0A844QCC7_9BACL/1-218 AC A0A844QCC7.1
#=GS A0A1M7A6Q2_9FIRM/42-210 AC A0A1M7A6Q2.1
#=GS A0A839JY26_9FIRM/8-174 AC A0A839JY26.1
#=GS A0A1G6DUZ0_9STRE/1-199 AC A0A1G6DUZ0.1
#=GS A0A430AL86_9ENTE/4-208 AC A0A430AL86.1
#=GS A0A3M8LFC0_9MICO/52-227 AC A0A3M8LFC0.1
#=GS A0A2X3W5T8_9STRE/3-208 AC A0A2X3W5T8.1
#=GS A0A7X6MZW4_9STRE/1-184 AC A0A7X6MZW4.1
#=GS G7H0A3_9ACTN/45-224 AC G7H0A3.1
#=GS R7G0T4_9PROT/1-150 AC R7G0T4.1
#=GS A0A1L8RAU2_9ENTE/13-233 AC A0A1L8RAU2.1
#=GS B9DU85_STRU0/1-184 AC B9DU85.1
#=GS T1ZHF9_STRIT/1-184 AC T1ZHF9.1
#=GS A0A0R1YNB6_9LACO/20-59 AC A0A0R1YNB6.1
#=GS A0A3N0I668_9ACTN/15-92 AC A0A3N0I668.1
#=GS A0A173YFZ9_9CLOT/20-198 AC A0A173YFZ9.1
#=GS A0A1Z5ID35_9LACO/1-185 AC A0A1Z5ID35.1
#=GS A0A0D4CMW6_LIMMU/10-209 AC A0A0D4CMW6.1
#=GS A0A387BIT1_9LACT/31-242 AC A0A387BIT1.1
#=GS A8AZW3_STRGC/1-184 AC A8AZW3.1
#=GS A0A430ARW5_9ENTE/1-183 AC A0A430ARW5.1
#=GS A0A2S6CPC3_9CYAN/5-44 AC A0A2S6CPC3.1
#=GS Q6LWI0_LACPL/1-205 AC Q6LWI0.1
#=GS A0A100YTV6_9ACTN/3-161 AC A0A100YTV6.1
#=GS A0A3N0I6B1_9ACTN/1-87 AC A0A3N0I6B1.1
#=GS A0A1I3BBQ2_9LACT/37-180 AC A0A1I3BBQ2.1
#=GS A0A3N0AQY3_9ACTN/15-201 AC A0A3N0AQY3.1
#=GS A0A4Q4IVM2_9BACL/9-185 AC A0A4Q4IVM2.1
#=GS A0A4P5P7H5_9ENTE/41-217 AC A0A4P5P7H5.1
#=GS A0A0S9C5T3_9MICC/1-115 AC A0A0S9C5T3.1
#=GS A0A2D1SX81_9BACL/13-174 AC A0A2D1SX81.1
#=GS A0A5N5RLH1_9BIFI/5-190 AC A0A5N5RLH1.1
#=GS A0A3A9EUV4_9BACT/14-187 AC A0A3A9EUV4.1
#=GS A0A095XZW8_9CORY/52-227 AC A0A095XZW8.1
#=GS A0A0R3QHC2_9BILA/2-185 AC A0A0R3QHC2.1
#=GS A0A1V4T113_9GAMM/1-65 AC A0A1V4T113.1
#=GS K0YZC3_9ACTO/152-291 AC K0YZC3.1
#=GS A0A7K3L5K4_9ACTN/1-108 AC A0A7K3L5K4.1
#=GS A0A1G6D7X6_9STRE/1-184 AC A0A1G6D7X6.1
#=GS A0A2S6CP50_9CYAN/1-184 AC A0A2S6CP50.1
#=GS R9N3N9_9FIRM/7-193 AC R9N3N9.1
#=GS T0S4B5_LACLC/2-185 AC T0S4B5.1
#=GS A0A7L4YR70_9ACTN/53-227 AC A0A7L4YR70.1
#=GS R9M3T5_9FIRM/5-185 AC R9M3T5.1
#=GS A0A7X6S4J6_9LACO/1-205 AC A0A7X6S4J6.1
#=GS A0A5C5T9M9_9STRE/27-153 AC A0A5C5T9M9.1
#=GS A0A6N6NL64_9ACTN/14-164 AC A0A6N6NL64.1
#=GS A0A6M0L6A2_9LACT/7-219 AC A0A6M0L6A2.1
#=GS A0A4R5NCQ4_9LACO/21-204 AC A0A4R5NCQ4.1
#=GS K9B461_9MICO/49-224 AC K9B461.1
#=GS R5ENB8_9FIRM/3-193 AC R5ENB8.1
#=GS A0A2A5RKV6_9LACT/3-193 AC A0A2A5RKV6.1
#=GS A0A396S2G6_9BACI/3-187 AC A0A396S2G6.1
#=GS A0A1T4YAB2_9DELT/7-223 AC A0A1T4YAB2.1
#=GS R9LA03_9ACTN/1-183 AC R9LA03.1
#=GS V7HUG0_9LACO/1-184 AC V7HUG0.1
#=GS A0A4S3B2U2_9ENTE/4-188 AC A0A4S3B2U2.1
#=GS A0A087AZJ0_9BIFI/2-186 AC A0A087AZJ0.1
#=GS A0A387BH76_9LACT/1-184 AC A0A387BH76.1
#=GS A0A3A9IAX2_9FIRM/36-174 AC A0A3A9IAX2.1
#=GS D7GRK9_9FIRM/14-198 AC D7GRK9.1
#=GS A0A2A3Z719_9MICO/53-208 AC A0A2A3Z719.1
#=GS Q5FLQ6_LACAC/12-204 AC Q5FLQ6.1
#=GS A0A6N6NNW5_9ACTN/21-211 AC A0A6N6NNW5.1
#=GS C5C9K3_MICLC/42-227 AC C5C9K3.1
#=GS A0A845R5Q8_9FIRM/70-234 AC A0A845R5Q8.1
#=GS A0A0R2KTL6_9LACO/1-216 AC A0A0R2KTL6.1
#=GS R3WMW5_9ENTE/6-188 AC R3WMW5.1
#=GS R5TRV5_9FIRM/28-211 AC R5TRV5.1
#=GS K6DER7_SCHAZ/1-177 AC K6DER7.1
#=GS G5KF66_9STRE/3-197 AC G5KF66.1
#=GS A0A2S6CP56_9CYAN/4-188 AC A0A2S6CP56.1
#=GS A0A179ERG0_ENTTH/41-165 AC A0A179ERG0.1
#=GS A0A0R1YN24_9LACO/1-50 AC A0A0R1YN24.1
#=GS A0A3A9HA94_9FIRM/12-196 AC A0A3A9HA94.1
#=GS T0TBK9_LACLC/1-76 AC T0TBK9.1
#=GS A0A1R4IJ82_9ACTN/64-188 AC A0A1R4IJ82.1
#=GS A0A3L8JDU1_STRIN/3-198 AC A0A3L8JDU1.1
#=GS A0A087DBM7_9BIFI/6-190 AC A0A087DBM7.1
#=GS A0A180ETQ8_9BACT/5-190 AC A0A180ETQ8.1
#=GS A0A1Y3WZ50_9FIRM/1-158 AC A0A1Y3WZ50.1
#=GS M2X9N6_9MICC/53-227 AC M2X9N6.1
#=GS A0A429ZRW1_9ENTE/1-184 AC A0A429ZRW1.1
#=GS F5X3W2_STRPX/1-184 AC F5X3W2.1
#=GS E1M5N5_9STRE/1-184 AC E1M5N5.1
#=GS I7JV74_9LACO/1-188 AC I7JV74.1
#=GS B8DWT5_BIFA0/9-191 AC B8DWT5.1
#=GS A0A4Q0VHJ7_9LACO/1-108 AC A0A4Q0VHJ7.1
#=GS A0A0R1MG53_9LACO/1-205 AC A0A0R1MG53.1
#=GS K8E7B8_CARML/3-204 AC K8E7B8.2
#=GS R5VXD3_9DELT/1-185 AC R5VXD3.1
#=GS A0A0E4CTX3_9STRE/1-205 AC A0A0E4CTX3.1
#=GS A0A1I3HWX1_9FIRM/4-204 AC A0A1I3HWX1.1
#=GS S1QY20_9ENTE/1-184 AC S1QY20.1
#=GS F9PM40_9ACTO/43-220 AC F9PM40.1
#=GS A0A6N6NPH9_9ACTN/1-76 AC A0A6N6NPH9.1
#=GS A0A852XCG0_9MICO/49-224 AC A0A852XCG0.1
#=GS A0A6N8JLN0_9ACTN/1-181 AC A0A6N8JLN0.1
#=GS H3NHH4_9LACT/1-91 AC H3NHH4.1
#=GS I7L558_9LACO/1-191 AC I7L558.1
#=GS A0A192H4M7_9LACO/21-204 AC A0A192H4M7.1
#=GS G9ZK09_9LACO/1-205 AC G9ZK09.1
#=GS A0A091BW94_9ENTE/3-188 AC A0A091BW94.1
#=GS R7A431_9FIRM/35-214 AC R7A431.1
#=GS U6FMK8_LACHE/1-205 AC U6FMK8.1
#=GS A0A086ZH40_9BIFI/3-186 AC A0A086ZH40.1
#=GS A0A2N6PK40_9MICO/52-227 AC A0A2N6PK40.1
#=GS A0A5C5TDU6_9STRE/1-184 AC A0A5C5TDU6.1
#=GS K9AG62_9STAP/1-184 AC K9AG62.1
#=GS A0A139NDS1_9STRE/26-178 AC A0A139NDS1.1
#=GS A0A3S8Z9Y7_9ACTO/53-226 AC A0A3S8Z9Y7.1
#=GS U2TJ01_9ACTN/2-181 AC U2TJ01.1
#=GS A0A147E9Q6_9MICC/52-227 AC A0A147E9Q6.1
#=GS A0A1U7EF07_9LACT/12-189 AC A0A1U7EF07.1
#=GS U7VC90_9FUSO/1-185 AC U7VC90.1
#=GS A0A1G6DUV1_9STRE/1-208 AC A0A1G6DUV1.1
#=GS A0A143HEB4_9BACL/2-186 AC A0A143HEB4.1
#=GS A0A3A8ZC79_9BACT/5-194 AC A0A3A8ZC79.1
#=GS A0A087EKU7_9BIFI/5-190 AC A0A087EKU7.1
#=GS A0A380KA39_9STRE/1-184 AC A0A380KA39.1
#=GS A0A416K0X8_9FIRM/1-159 AC A0A416K0X8.1
#=GS A0A1T4WRJ9_9FIRM/4-177 AC A0A1T4WRJ9.1
#=GS A0A839K6F9_9FIRM/2-192 AC A0A839K6F9.1
#=GS A0A1Q2CYY8_9ACTN/52-208 AC A0A1Q2CYY8.1
#=GS R5LPG3_9MOLU/1-183 AC R5LPG3.1
#=GS W4EN49_9BACL/13-199 AC W4EN49.1
#=GS G3K0V5_LENBU/21-204 AC G3K0V5.1
#=GS K9ACT1_9STAP/1-134 AC K9ACT1.1
#=GS Q5FMZ1_LACAC/1-189 AC Q5FMZ1.1
#=GS A0A288Q8B2_9LACO/1-190 AC A0A288Q8B2.1
#=GS F9PY17_9STRE/1-184 AC F9PY17.1
#=GS A0A7J5BUA6_9MICO/53-223 AC A0A7J5BUA6.1
#=GS A0A7K1J5Y4_9BIFI/6-190 AC A0A7K1J5Y4.1
#=GS A0A3A9D3G1_9BACT/114-299 AC A0A3A9D3G1.1
#=GS S3WZK9_9ACTN/40-217 AC S3WZK9.1
#=GS W7D2V3_9LIST/4-190 AC W7D2V3.1
#=GS A0A3N0II49_9ACTN/7-180 AC A0A3N0II49.1
#=GS A0A2S6CP47_9CYAN/1-144 AC A0A2S6CP47.1
#=GS J1HFM2_9ACTO/43-220 AC J1HFM2.1
#=GS A0A1T4SPD9_9FIRM/1-134 AC A0A1T4SPD9.1
#=GS E6KSW0_9ACTO/39-220 AC E6KSW0.1
#=GS A0A3P1V884_9ACTO/43-220 AC A0A3P1V884.1
#=GS A0A0R1YLM2_9LACO/1-153 AC A0A0R1YLM2.1
#=GS A0A022KV00_9MICO/47-180 AC A0A022KV00.1
#=GS A0A8J2YP40_9BACL/1-205 AC A0A8J2YP40.1
#=GS A0A2S6CNV9_9CYAN/4-187 AC A0A2S6CNV9.1
#=GS R5WLG4_9FIRM/8-220 AC R5WLG4.1
#=GS A0A0C2FWG3_9BILA/1-167 AC A0A0C2FWG3.1
#=GS REPP_ONYPE/9-187 AC Q8G8D1.1
#=GS A0A429QQC2_9ACTN/5-190 AC A0A429QQC2.1
#=GS K6C7F6_9BACI/1-184 AC K6C7F6.1
#=GS A0A7X1Z7F5_9LACT/7-195 AC A0A7X1Z7F5.1
#=GS A4VUP1_STRSY/14-211 AC A4VUP1.1
#=GS U5SDM9_9LACT/2-187 AC U5SDM9.1
#=GS A0A2S6CQF6_9CYAN/47-234 AC A0A2S6CQF6.1
#=GS A0A2A5RUZ9_9LACT/3-186 AC A0A2A5RUZ9.1
#=GS Q5FM55_LACAC/1-191 AC Q5FM55.1
#=GS A0A542X8H2_9MICO/56-212 AC A0A542X8H2.1
#=GS A0A3L8GQR8_STRIN/3-186 AC A0A3L8GQR8.1
#=GS R9M2M1_9FIRM/9-111 AC R9M2M1.1
#=GS Q6YPQ8_ONYPE/8-194 AC Q6YPQ8.1
#=GS G8PF46_PEDCP/1-216 AC G8PF46.1
#=GS R6WAW3_9FIRM/1-184 AC R6WAW3.1
#=GS A0A380LH74_9FIRM/51-147 AC A0A380LH74.1
#=GS A0A849A8M9_9ACTN/52-208 AC A0A849A8M9.1
#=GS K9ACR5_9STAP/1-40 AC K9ACR5.1
#=GS A0A2R5HHD4_9LACT/4-187 AC A0A2R5HHD4.1
#=GS R5K9J9_9CLOT/4-189 AC R5K9J9.1
#=GS A0A3S0ADE3_9ENTE/16-176 AC A0A3S0ADE3.1
#=GS R9KXH1_9FIRM/1-171 AC R9KXH1.1
#=GS A0A4Y8KME0_9MICO/16-153 AC A0A4Y8KME0.1
#=GS A0A087E8F3_9BIFI/3-186 AC A0A087E8F3.1
#=GS K6DG47_9BACI/22-160 AC K6DG47.1
#=GS A0A0R1ZBS7_9LACO/20-172 AC A0A0R1ZBS7.1
#=GS R7HEM9_9MOLU/1-182 AC R7HEM9.1
#=GS H3NHH1_9LACT/11-104 AC H3NHH1.1
#=GS A0A0E4H4M5_9STRE/17-212 AC A0A0E4H4M5.1
#=GS A0A3S0V1Y1_9MICC/52-227 AC A0A3S0V1Y1.1
#=GS A0A1D8B3A3_9ACTO/43-220 AC A0A1D8B3A3.1
#=GS A0A0R1ZE48_9LACO/7-196 AC A0A0R1ZE48.1
#=GS A0A437SV55_9LACO/1-188 AC A0A437SV55.1
#=GS A0A2S6CP25_9CYAN/3-190 AC A0A2S6CP25.1
E1MA47_9STRE/1-201 ...................................................m----VKARNIMF...VQQI......EYF..qS...SNLQDii..........eyMTNT.L.KPI.RFAGILHDKD...............I..........G.....Q............D...........G....N......L.V........TP........HIHLVLQ.F..ESAR..SLNN..LAK-......L..TK.QP.IQCF...EQWRG..........SVNNAYS....YLVHHTEs..nQDKYQ..YSPK.......E.V--.IANF..D..YLLL...........LD...T..IEK.......N.VTKRyEINDT.MI........IDN-...................------.......-------.---.......------.-.-.-.........--.-.-.--------lldllyigditkseieqrltgsqyakarqkietvylkrletqaelwrqemidkne..............................................................................
A0A139N8X2_9STRE/3-186 ...................................................k-SKEKRSNKWAF...LLYQ......DSA...P...ENYLD..............ILEE.M.HIP.FVLSPWHDKD...............I..........N....kE............T...........G....E......F.K........KS........HKHGALY.F..DSLK..SYSQ..VSEL......L..TK.KL.NTPA..hVEIVM..........SPKGMYD....YFTHAEN....PDKTL..YNIE.......E.IES.GCGF..E..LDKF...........LI...E..HNS.......G.LFLE.TVIDV.IT........ENDF...................TEFEDL.......VRYARFN.DNS.......LLGLII.E.R.T.........YF.F.T.KFLDSRRH.....................................................................................................................................
A0A3A9HF83_9FIRM/40-215 .......................................kiiksrlenagce------------...----......---...-...-----..............----.-.-IL.EMHGIRHDKD...............E..........N....kI............W...........N....E......Y.KmdydinfqSN........HAHFIAK.F..KKGKgkTLPE..LAKI......-..--.--.VGVE...ESYIEkpk...sgryAFDNMLS....YLIHIKY....DKKYQ..YDVH.......T.VYT.FAGK..K..YI--...........--...-..EHY.......R.ERYE.SWMRG.RA........KKSV...................ASTKEL.......VDFLING.IADg....aiTFDNIV.S.N.E.........EW.M.K.VY------iinssri..............................................................................................................................
A3CR50_STRSV/1-184 ...................................................m-AKEQRSTKWTF...LFYE......ESA...P...EDYLT..............ILEE.L.HIP.FILSPWHDKD...............V..........N....kQ............T...........G....E......F.K........KS........HKHGAFF.F..DSLK..SYSQ..VSNI......I..SD.KL.NGPA..hVEVVM..........SPTGLFD....YFTHAEN....PDKTP..YNIE.......D.IEV.GCGF..N..LEKF...........LM...E..MNS.......S.DFIH.EVVDI.IE........ENDF...................TEFEEL.......VWYARAN.NTN.......LLGLII.E.R.T.........YF.F.A.KYLDSRRY.....................................................................................................................................
A0A380Q0Z5_9FIRM/19-201 .................................................kra---GTRTRNYAT...VVYP......ESA...P...ADWKN..............KLEQ.T.FIP.CLISPLHDKD...............I..........N.....P............G...........G....E......P.K........KP........HYHVLLA.F..EGVK..TKAQ..AQE-......V..FD.TI.GGVG...CEVVN..........SVRGYAR....YLCHLDN....PEKAR..YAES.......Q.VTQ.YGGL..D..YYDV..........iGL...A..SDK.......H.KAIR.EMIEY.CK........DTGV...................IEYADL.......LEYAMYE.RED.......WFRVLC.D.C.G.........TFtM.Q.NYLKSRRH.....................................................................................................................................
A0A4S3B3N7_9ENTE/30-297 ..........................kiiddarnnsieplikeiikkieeed------------...----......---...-...-----..............----.C.IVS.EAYGIKHDKDei...........svW..........D....tQ............T...........KtyisN......T.K........TT........HIHLLIK.F..EKGA..TLEN..LASY......I..GL.E-.-SQY...LEKAKsg......ryGYDNLLA....YLIHAKD....RDKYP..YSPE.......E.VIT.VRGE..N..YLTI...........YN...Q..K--.......-.----.-----.--........----...................------.......-------.---.......------.-.-.-.........--.-.-.--------keswtkgratkeaseanlsvdyliseilegniskneilltddyyktyalnqrkiddafsvytekkglktinalengefkktilfitgdsgagktvfsklliskikqlakeknerwehcmtastnpfdeyngqe
A0A844QCC7_9BACL/1-218 ...................................................m-TNKEKSRYFTF...LLYP......ESI...P...NDWEM..............KLEL.L.GLP.IAISPLHDRDeter.......kfedL..........S.....E............Eeqki...irsgG...kV......Y.K........KA........HYHVIYI.A..KNPV..TVDS..VRKR......I..QR.TL.GKQS...VAMVQiv......trSVENVYL....YLTHESKdaiaKKKHV..YDKK.......D.IKL.LNNF..D..IDRYv.........tID...D..NEK.......K.ELRQ.TLLEI.IA........EYKI...................VNVIEL.......NAFIIKN.GKQ.......FGINGM.R.-.-.........-Y.V.N.EVI-----snssgifrlyfdanyqn....................................................................................................................
A0A1M7A6Q2_9FIRM/42-210 .......................................qtltemeesvaem------------...----......QKL...I...NNIIE..............NFDK.N.-EI.IIIAIIHSRD...............V..........V.....A............D...........A....EdpflpsV.E........KP........HAHFIIK.F..KNYK..KRIH..ISTLl...nmL..DI.HF.RNPE..dATLFKkg......ceSLGGSYRenaiYLLHNSAqaikDGKAE..YKPE.......EfIAN.LSKT..E..IESL...........I-...-..---.......-.----.-----.--........----...................------.......-------.---.......------.-.-.-.........--.-.-.--------ngklnldkspkptlefltaldqtayn...........................................................................................................
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A0A2S6CNV9_9CYAN/4-187 ...................................................k-KEIVKGRDWTF...IVYP......ESA...P...ENWRT..............ILDE.T.FMR.WVESPLHDKD...............V..........N.....A............D...........G....E......I.K........KP........HWHILLS.S..DGPI..TQTA..VQK-......I..IG.PL.NCPN...AQKVG..........SAKGLVR....YMVHLDN....PEKYQ..YSLD.......E.IVG.HNGA..D..VASYf.........eLT...A..TNK.......L.VLMK.EMISF.IY........ENNI...................DNYAEF.......LMLCIEK.SDD.......WFNVAI.NyN.T.........LA.I.N.KMIDAVW-q....................................................................................................................................
R5WLG4_9FIRM/8-220 ...................................kkkkdrtpktwktceii------------...--QQ.....lEYM..sA...EDVGS..............GLDH.N.AIK.DYAYILHDKD...............V..........N.....D............D...........G....S......P.K........AA........HWHIYIR.F..KDST..PTDS..ICKW......F..-G.I-.TSNY...IGRIQ.........gRFADALA....YATHRNV....PEKYQ..YLDE.......E.V--.KSNF..D..FVKErd.......taRS...K..EAD.......K.QRKA.EISDL.II........SGVI...................REY-NY.......TDYITIQ.EYD.......RF----.-.-.-.........--.-.-.--------rksidnafkyrldkikgenrdmeviyifgdsscgkttyakelaaq........................................................................................
A0A0C2FWG3_9BILA/1-167 ....................................................------------...----......-SA...P...ENWRD..............VISS.W.QCE.CLVSPLHDKD...............V..........N.....A............D...........G....T......P.K........KP........HWHGILF.F..ESKK..TQEQ..AEE-......L..TA.AL.NGPK..pIRPSG..........SKRTACR....YLIHADN....PEKAQ..YGAA.......D.VLE.FGGA..S..LSMY..........sIR...E..AEN.......E.TLVQ.EMVEW.CE........KYEC...................FSYRLL.......LQYSMRN.KPE.......WFRALC.R.S.C.........TY.VmK.EYLKS---ayr..................................................................................................................................
REPP_ONYPE/9-187 ..................................vinktlitktkietilet------------...----......---...-...-----..............--KK.K.AIQ.NYAYILHDKD...............I..........Y....qN............Ekeaql.ngkkvG....D......I.K........AP........HWHIYLR.F..NYSQ..DTKH..ISQW......F..NT.Q-.-ENF...VSKIK.........gRFSDALM....YMIHANR....LDKHQ..YDEK.......E.V--.VSNF..D..WKS-...........EA...Q..QDIfnrkykmD.ARLK.DILLK.IH........SGEI...................------.......KEYNIND.N--.......------.-.-.-.........--.-.-.--------inilenniyataiekafkfri................................................................................................................
A0A429QQC2_9ACTN/5-190 .................................................asq--DKVRTRNWTF...IIYP......ESV...F...QNWRD..............VLDN.E.HIQ.WVESPLHDKD...............T..........N.....P............D...........G....E......I.K........KA........HKHILVM.Y..DGVK..SYNQ..ILE-......L..TE.KI.NATV...PQKCG..........SAKGLVR....YMLHMDN....PEKYQ..YNRE.......D.MVA.HGGA..D..IAEMl.........kPT...S..ASR.......Y.EMFK.EMTSF.IV........ENDI...................REYEDL.......WIYAMEN.RFD......dWFPLLA.D.N.G.........TFaI.N.TFIKSRRH.....................................................................................................................................
K6C7F6_9BACI/1-184 ....................................................MTKEQRSNKWAF...LFYK......ESA...P...DNYLE..............KLEE.I.HVP.FVLSPWHDKD...............I..........N....kE............T...........G....E......L.K........KS........HKHGTFY.F..DSLK..SYSQ..VSEL......I..KD.KL.NGPA..hVEPVM..........SPKGMYD....YFIHAEN....PDKAP..YNIE.......D.IES.GCGF..E..LDKF...........LV...Q..QNS.......D.DFTT.EVIDT.IE........QNDF...................TEFEEL.......VWYARDN.NTA.......LLGLII.E.R.T.........YF.F.A.RYLDSRRH.....................................................................................................................................
A0A7X1Z7F5_9LACT/7-195 .................................................kks--ATPRCHNWGL...IVYS......ESA...P...ENWRD..............ILKE.E.GVP.F-AYILHDKD...............T..........Ki...dE............N...........G....Ev....vL.K........KP........HYHIILK.Y..RNQK..SYQQ..MMV-......L..TG.RL.RAPN...PMRIE..........SLVGYAR....DFLHLDE....ESKYQfkYRIS.......E.VHV.FRGF..D..FQDLv.........kPN...K..TEL.......H.DILR.DIRSI.IR........NEGI...................TEIKVL.......YDYLDEI.NHD.......YSRVLD.S.K.C.........YP.I.D.RYISSSRH.....................................................................................................................................
A4VUP1_STRSY/14-211 ...............................................krkms-EKVPSIRHTAY...MFCSt....vESV..sI...KNLQEii..........klFQET.L.NPF.EIAGIIHDKD...............I..........D.....-............-...........-....-......-.T........EP........HYHIIVR.F..KNAV..WLNS..IINK......L..SQ.NG.FEVQ...SNFFEaw......kgKVNNAYS....YLIHRTEd..aSEKHQ..YTVD.......E.V--.----..-..----...........IA...N..FDY.......A.ERIE.NIESK.IQ........SNSRkektinvvrnlinkiiagdISFDEA.......IK-----.---.......------.-.-.-.........--.-.-.--------evdgytlvkydrefsrakkrrteid............................................................................................................
U5SDM9_9LACT/2-187 .................................................kkq-KKEKRSSKWTF...IIYE......ESV...P...KNYLD..............ILEE.M.QVP.FVLSPWHDKD...............V..........D....kE............T...........G....A......V.Q........KS........HKHGALF.F..DSLK..SYSQ..VSDL......I..SE.NL.NAPK..hVEPVH..........SPKGMYD....YFIHAQS....PDKAP..YNIE.......D.IES.GSGF..D..IAKF...........LM...E..QES.......G.TFLN.TVIDI.IE........EQDF...................TNFDSL.......VSYARKN.NSL.......LLSLIV.D.K.T.........YF.F.A.RLLDSRK-f....................................................................................................................................
A0A2S6CQF6_9CYAN/47-234 ..............................hewrkqmvdmftaiqddceycy------------...----......---...-...-----..............----.-.---.---FIFHDKD...............V..........L.....P............N...........G....D......K.K........GL........HVHFVIK.F..KNPR..VIRS..IMK-......T..FG.IS.RTEN...ISKVK..........SVKGSLS....YLLHITKqarkDGKFI..YGQDrlykvgtD.ISE.DDNF..E..HFNKl.........tVS...D..KDD.......K.DIKD.EIVEE.VL........----...................------.......-------.---.......------.-.-.-.........--.-.-.--------sqvtslrekgemadikilykkfpthknlvsdiyynyttkreyaereyfa....................................................................................
A0A2A5RUZ9_9LACT/3-186 ....................................................KKKEQRSNKWAF...LIYQ......DSA...P...ENYLD..............ILEE.L.HIP.YVLSPWHDKD...............V..........N....kS............T...........G....E......I.K........KA........HKHGALF.F..ETLK..SYSQ..VSDL......L..KD.KL.NSPA..hVEVVM..........SPKGMYD....YFTHAEN....PDKSP..YNIE.......D.IES.GCGF..E..LDKF...........IA...E..QAT.......D.EFLN.DIIDL.IE........ENHI...................TEFEDL.......VKYAREN.NYL.......LLSLII.D.K.T.........YF.F.A.RFIDSKR-f....................................................................................................................................
Q5FM55_LACAC/1-191 ....................................................MKKAIRARQFMY...TQDL......DHL...PfkkEDLKT..............LLEK.S.SAE.EWAYILHDKD...............I..........G.....K............N...........G....K......T.I........RP........HFHVVMK.F..KDAK..TISR..VAKL......F..ND.K-.-QEY...IEVWR.........nTIGNAYS....YLIHETSn..aKDKHH..YDPI.......E.V--.VSSF..D..FETKi........kqIR...K..KVA.......K.LSKK.DIDDL.IDd......ySNEIl................tkT-----.......-------.---.......------.-.-.-.........--.-.-.--------dlqekigvlemakhktlldhiddilaykkhqkflk..................................................................................................
A0A542X8H2_9MICO/56-212 .............................................rleavgc------------...----......---...-...-----..............----.-.EVV.EAYGIVHDKD...............E..........R....eVws........dtE...........KalvvE......P.K........PD........HLHAVIK.F..ASRS..KSAP..LDR-......L..AS.G-.IGVE...PQYVEkpg...rgryAFDNMLS....YLTHVKY....ADKHQ..YAPS.......E.VAT.VRGP..D..YL--...........--...-..---.......-.----.-----.--........----...................------.......-------.---.......------.-.-.-.........--.-.-.--------gidalrretwlkgrahvkkkvvaenfedmrervlqgeitrdqiml........................................................................................
A0A3L8GQR8_STRIN/3-186 ....................................................KKKEQRSNKWAF...LIYQ......DSV...P...ENYLD..............ILEE.L.HIP.YVLSPWHDKD...............V..........N....kS............T...........G....E......I.K........KA........HKHGALF.F..ETLK..SYSQ..VSDL......L..KD.KL.NSPA..hVEVVM..........SPKGMYD....YFTHAEN....PDKSP..YNIE.......D.IES.GCGF..E..LDKF...........IA...E..QAT.......D.EFLN.DIIDL.IE........EKHI...................TEFEDL.......VKYAREN.NYL.......LLSLII.D.K.T.........YF.F.A.RFIDSKR-f....................................................................................................................................
R9M2M1_9FIRM/9-111 .................................ylppgikmasdlaahienv------------...----......---...-...-----..............----.L.APK.EYAVILHDQD...............I..........S.....E............D...........G....T......P.A........EA........HLHAMLC.F..RNAR..YLSA..VAKA......L..GD.K-.-EQY...VQKWD.........gEANNGHA....YLIHATRkaqkAGKHP..Y---.......-.---.----..-..----...........--...-..---.......-.----.-----.--........----...................------.......-------.---.......------.-.-.-.........--.-.-.--------trv..................................................................................................................................
Q6YPQ8_ONYPE/8-194 ........................................lvinsnlinqsk------------...----......---...I...ENILE..............AK-K.N.AIQ.NYAFILHDKD...............I..........Y....qN............Ekeaql.ngkkiG....D......L.K........TP........HWHIYLR.F..NNAY..DVKH..IAQW......F..NT.E-.-ENF...VSKIK.........gRFSDALM....YMIHANR....TDKHQ..YDER.......E.V--.VSDF..D..WKSEaqq.....difLR...K..YKI.......D.TRLK.DILTK.IH........SGEI...................KEYN-I.......TNYIS--.---.......------.-.-.-.........--.-.-.--------iiehniysaaiekafkyrtntlkgie...........................................................................................................
G8PF46_PEDCP/1-216 ...................................................m--AKDKSRYFTF...LLYP......ESI...P...EDWKS..............KLEL.I.GVP.IAISPFHDMD...............E..........K.....TdkskwtpddvirN...........G...kH......Y.K........KP........HYHVVYV.A..KNPV..TADS..VRYK......I..KQ.LL.GDRS...IAKVQiv......irSMASMYS....YLTHESKdaieKKKHK..YNKK.......D.ITL.INNF..D..IDRYi.........sLD...V..EDK.......D.DMLN.DVCDL.ID........DHNL...................ANMREL.......RRFLKAH.GSEy....gmPSIKVV.N.S.VlrahtglirLY.F.D.AVYQERKY.....................................................................................................................................
R6WAW3_9FIRM/1-184 ....................................................MEKQKRTRNFAT...VVYPt....sEKT...P...ENWQD..............ILRE.Q.IIP.AFISPLHDKD...............K..........N.....T............T...........G....E......V.K........KA........HYHIIIM.F..EGVK..TIEQ..ARE-......V..FD.LI.GGVG...IEPIK..........SIRAYVR....YLCHLDN....PEKAQ..YSIE.......D.VIC.CSGA..D..YQSM..........iES...P..QDK.......Y.ILLG.EIMDY.CE........QKDI...................VSYAEL.......LKYAREN.NRA.......WFIVLC.D.N.T.........LP.V.V.QYLKSR--yw...................................................................................................................................
A0A380LH74_9FIRM/51-147 ................................................hlsk----LKKRHWMY...IVYP......ESA...P...KDWMQ..............QLEA.T.GVK.FAVSPLHDKD...............K..........L.....V............D...........G....K......Y.K........KK........HWHLILI.F..DGPT..TFMT..AAS-......Y..IG.IT.NGPY...PKVCE..........SLRGLYE....-------....-----..----.......-.---.----..-..----...........--...-..---.......-.----.-----.--........----...................------.......-------.---.......------.-.-.-.........--.-.-.--------nhsn.................................................................................................................................
A0A849A8M9_9ACTN/52-208 .............................................rleavgc------------...----......---...-...-----..............----.-.EVV.EAYGIVHDKD...............E..........R....eVws........dtE...........KalvvE......P.K........PD........HLHAVIK.F..ASRS..KSAP..LDRL......A..FG.I-.-GVE...PQYVEkpg...rgryAFDNMLS....YLTHVKY....ADKHQ..YAPS.......E.VAT.VRGP..D..YL--...........--...-..---.......-.----.-----.--........----...................------.......-------.---.......------.-.-.-.........--.-.-.--------gidalrretwlkgrahvkkkvvaenfedmrervlqgeitrdqiml........................................................................................
K9ACR5_9STAP/1-40 ....................................................-----------M...VVYP......ESA...P...ENWEE..............LLAE.T.FMQ.FAVSPLHDKD...............T..........N.....P............D...........G....E......I.K........--........-------.-..----..----..----......-..--.--.----...-----..........-------....-------....-----..----.......-.---.----..-..----...........--...-..---.......-.----.-----.--........----...................------.......-------.---.......------.-.-.-.........--.-.-.--------.....................................................................................................................................
A0A2R5HHD4_9LACT/4-187 ..................................................kt-KKEQRSNKWAF...LFYQ......ESA...P...EDYLN..............ILEE.L.HVP.FILSPWHDKD...............V..........N....rS............T...........G....G......F.K........KA........HKHGAFF.F..DSLK..SYSQ..VSDL......I..SD.KL.NGPA..hVEVVM..........SPKGMYD....YFTHAEN....PEKTP..YNVE.......D.IES.GAGF..E..LDKF...........LA...E..NNP.......D.-LLL.QVYEI.MH........DSNL...................KEFADF.......TDLIAQK.YPD.......LLFYVF.D.K.S.........YF.F.K.IYLDSKRY.....................................................................................................................................
R5K9J9_9CLOT/4-189 .......................................kkgepsswrtcei------------...VQQL......EYM..sQ...EDVEA..............GLDH.N.AVQ.DYAYILHDKD...............V..........H.....E............D...........G....T......P.V........AP........HWHIMIR.F..KRPV..QTES..LCKW......F..-G.IK.SNMI...GYILG..........TFGDAVA....YLTHRNK....PEKYQ..YLDE.......E.IKS.NYDFkvE..VEKA...........LS...K..KKA.......S.QRKE.EIIEL.IR........SG-I...................VREYNY.......TEYITAL.EYD......kFKRAID.N.A.F.........TY.R.-.--------rdtlksldrh...........................................................................................................................
A0A3S0ADE3_9ENTE/16-176 ......................................eltevlekivkakr------------...----......---...-...-----..............----.-.---.-YAFIIHDDN...............-..........E.....-............-...........-....-......-.E........FK........HIHIILE.F..ENAR..HITS..IAK-......L..LD.I-.EPQY...IEVWK.........gSIKNAYS....YLLHRTDearkENKKQ..YSPK.......N.V--.VANF..D..FE--...........MS...I..NEI.......E.TILS.NNKDL.KNk......rKNEV...................NKLIEL.......F------.---.......------.-.-.-.........--.-.-.--------dlkiidkqallenlsgieyahnektiisiekmhl...................................................................................................
R9KXH1_9FIRM/1-171 ....................................................------------...MVYP......ESA...P...DDWII..............KLQE.Q.CVP.ALISPLHDKD...............I..........N.....A............D...........G....T......R.K........KE........HYHVMIL.F..EGVK..TSEQ..AKE-......V..FS.AI.GGVG...IEPLK..........CARAYAR....YLCHLDN....AEKAQ..YDIE.......N.VIS.CSGA..D..YMAM..........iSL...A..TDK.......Y.SAIG.EMLEF.CI........QNEI...................VSYARL.......PLFAKEN.RQD.......WFRVLC.D.NgT.........LT.I.V.QFLKSR--yw...................................................................................................................................
A0A4Y8KME0_9MICO/16-153 .................................rrfsvvsnfirridietaf------------...----......---...-...-----..............--DR.P.NVV.RYAGCVHDKD...............F..........E.....-............-...........-....-......-.T........AT........HGHAFAE.F..KDGR..TVDQ..VKD-......F..FD.KP.VIVT...PLVGKsg.....dttSFARAVR....YLTHEHQsqqaLGKYH..YPDT.......D.VFV.SEGF..D..WRTE...........--...-..---.......-.----.-----.--........----...................------.......-------.---.......------.-.-.-.........--.-.-.--------vnaltarenntarpnvrqir.................................................................................................................
A0A087E8F3_9BIFI/3-186 .................................................tkn---YGKGRYWAG...LIYQ......DSC...P...MDWEE..............RMRF.S.GLQ.ILVSPLHDSD...............I..........Ad...pK............T...........G....E......L.K........KP........HRHVIAM.W..SNTT..TKAN..AEKF......F..AQ.FN.GPKV...ILRLE..........SPRGMAR....YLVHLDD....PQKAQ..YSPR.......D.VIE.INGA..D..WRKL..........aLT...N..GSK.......D.EAM-.SIVRV.VE........DEGP...................DGYFTL.......LKICQEK.HKE.......LLDFAT.R.Q.V.........VF.C.R.EVIWSYWH.....................................................................................................................................
K6DG47_9BACI/22-160 ..................................................kqKKKEQRSNKWAF...LIYQ......ESV...P...EDYLN..............LLEE.L.HVP.FILSPWHDKD...............V..........N....rT............T...........G....E......F.K........KP........HKHGVFF.F..ESLK..SYSQ..VSEL......I..SD.KL.NSPE..hVEVVM..........SPKGMYD....YFTHAEN....PEKSP..YNIE.......D.IES.GAGF..E..LDKF...........LA...E..NNE.......D.----.-----.--........----...................------.......-------.---.......------.-.-.-.........--.-.-.--------llnqg................................................................................................................................
A0A0R1ZBS7_9LACO/20-172 ........................................svlikriknvpe------------...----......---...-...-----..............----.-.-IK.RYALIIHDKD...............S..........D.....K............D...........G....N......A.I........KP........HVHVMLE.L..DKQR..SVNK..IAKA......L..DD.S-.SERL...ESMIKky.....krhGIENGYA....YLIHQTQg..aEKKYQ..YSPE.......K.V--.KANF..D..YPKY...........IK...K..LQQ.......-.----.-----.--........----...................------.......-------.---.......------.-.-.-.........--.-.-.--------rvrvtnkksdkefikevlnnylagkiseieakrkvlean..............................................................................................
R7HEM9_9MOLU/1-182 ..................................................mi-----KKRNWGA...VIYP......ESA...P...VDWID..............ILKI.K.GIT.FAVSPLHDKD...............L..........Dn...gS............N...........G...tQ......L.K........KA........HYHIIMC.F..DGPV..TDKT..VND-......L..LH.SL.NQPI...GIPLE..........SVRGYYR....YFTHKDN....PEKYQ..YDEK.......E.IRL.FNGF..D..VSDV...........LN...G..FEV.......Y.QHMK.EIQNL.II........ENDI...................IEYCDL.......IDYLLIN.DYG......eLWNVAC.S.H.T.........LF.F.N.SYITSKRH.....................................................................................................................................
H3NHH1_9LACT/11-104 ...................................................n-KKNSRGRNWTF...VLYP......ESA...K...IDWLE..............YLKE.L.HIQ.FVVSPLHDKD...............K..........D.....A............E...........G....K......I.K........KA........HHHILVM.Y..ERGE..QMVR..AYDY......F..TK.KC.LGK-...-----..........-------....-------....-----..----.......-.---.----..-..----...........--...-..---.......-.----.-----.--........----...................------.......-------.---.......------.-.-.-.........--.-.-.--------kiilsmkdgttet........................................................................................................................
A0A0E4H4M5_9STRE/17-212 .................kskfwdwsiqdkqlfddwetnkekifrlifnrvra------------...----......---...-...-----..............LVEE.D.EFV.EFAIVVHDRD...............I..........S.....Y............G...........T....K......L.V........DP........HVHGYVD.F..PKLV..DLSK..VASI......L..GV.ER.ERIE...TPKSKgg.....rayTRINALA....YLIHAKD....KDKFQ..YPVS.......D.VET.FDTL..D..YEVF...........IN...-..QNK.......E.D---.-----.--........----...................------.......-------.---.......------.-.-.-.........--.-.-.--------fenysatrkrekaeekldlvlskvqsgeltyldvmkddklaflfannqqkf..................................................................................
A0A3S0V1Y1_9MICC/52-227 ............................................rleaigce------------...----......---...-...-----..............----.-.-VV.EAYGIVHDKD...............E..........RevwsdT............E...........KtlvvE......P.K........PD........HLHAVIK.F..ASRA..KSAP..LDRL......A..FG.I-.-GVE...PQYVEkpg...rgryAFDNMLS....YLTHVKY....ADKHQ..YAPS.......E.VAT.VRGP..D..YL--...........--...-..---.......-.----.-----.--........----...................------.......-------.---.......------.-.-.-.........--.-.-.--------gidaqrretwlkgrahvkkkvvaenfedmrervlqgeitrdqimltdelfdiysrhqreiddal.....................................................................
A0A1D8B3A3_9ACTO/43-220 ....................................eailayvvqrleatgc------------...----......---...-...-----..............----.-.EVV.EAYGIVHDKD...............E..........R....eVws........dtE...........KalviE......P.K........PD........HLHAVIK.F..ASRA..KSAP..LDRL......A..FG.I-.-GVE...PQYVEkpg...rgryAYDNMLS....YLTHVKY....ADKHQ..YAPS.......E.VAT.VRGP..D..YL--...........--...-..---.......-.----.-----.--........----...................------.......-------.---.......------.-.-.-.........--.-.-.--------gidaqrretwlkgrahvkkkvvaenfedmrervlqgeftrdqimltdelfdiysrhq............................................................................
A0A0R1ZE48_9LACO/7-196 .................................................kqd-KKDKRVRNWTF...IVYP......ESA...K...QDWRQ..............KLDD.L.HIP.WLESPLHDKD...............V..........N.....P............D...........G....T......K.K........KS........HWHILLK.F..GSKK..SYRQ..VKNL......T..QE.NV.GGTN...PQKVH..........DLRGMIR....YFIHIDN....PEKYQ..YSRT.......E.LKE.HCGF..D..IGKAf.........aSS...S..MQR.......Y.DLIH.EMIDF.IR........DNQI...................EEVSDL.......IAYAVDN.RAD......dWFPLLA.D.N.S.........LK.I.-.--------vesfirsihfkk.........................................................................................................................
A0A437SV55_9LACO/1-188 .................................................mse----LKSHNWMF...VQQKv....yLKV..sP...EQFQE..............ILEN.S.GAE.KWAYIFHDKD...............E..........G.....-............-...........-....-......-.V........EP........HFHVILH.Y..KNAS..RVST..VANL......F..KD.D-.-EER...VQRWD.........aRWNNACG....YLIHMTKnsaeDGRYP..YDIS.......E.V--.TANF..D..YAEK...........IS...Q..IQK.......RvSGTK.NITKV.IEq.....ygNHEI...................------.......-------.---.......------.-.-.-.........--.-.-.--------trqelelkigdaelaknhvwisriedlnakrehekflrefe............................................................................................
A0A2S6CP25_9CYAN/3-190 .................................................agv----KNRRSIMY...VQYL......EHI..kF...DSFDEle.........knvFKVV.G.DKY.QVASIIHDKD...............V..........S....dE............T...........G....E......L.E........RP........HIHMFFY.C..ENKL..SAAK..LMQ-......A..TN.ET.QMNQ...FEFFE..........RKDAGFL....YLIHAGRk..dRHKYQ..YSID.......E.V--.SANF..D..YREYv........enLKanyS..TSL.......D.TMLE.DVLESrIK........YSDI...................QNDNDL......sLLYAKNK.---.......------.-.-.-.........--.-.-.--------tkidnalniaskrrvea....................................................................................................................
#=GC seq_cons ........................................................................................th.p..............hhpt...tl..hhhu.lHDKD...............h..........p.....t............s...........G....c......h.K........cs........HhHsllh.F..pshp..ohpp..lsch......h..tp.h...sst...sphlp..........uhpshhp....YLsHhsp....s-Kap..Ys.p.......-.l...hssh..D..htph...........h........p..........thht.phhph.h.........t.th....................th..h..................................................................................................................................................................................................
//
