KEGG   Scheffersomyces stipitis: PICST_68020
Entry
PICST_68020       CDS       T01023                                 
Symbol
LYS2
Name
(RefSeq) L-aminoadipate-semialdehyde dehydrogenase, large subunit
  KO
K00143  L-2-aminoadipate reductase [EC:1.2.1.95]
Organism
pic  Scheffersomyces stipitis
Pathway
pic00300  Lysine biosynthesis
pic01100  Metabolic pathways
pic01110  Biosynthesis of secondary metabolites
pic01230  Biosynthesis of amino acids
Module
pic_M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
Brite
KEGG Orthology (KO) [BR:pic00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    PICST_68020 (LYS2)
Enzymes [BR:pic01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.95  L-2-aminoadipate reductase
     PICST_68020 (LYS2)
SSDB
Motif
Pfam: NAD_binding_4 AMP-binding PP-binding Epimerase 3Beta_HSD AMP-binding_C Polysacc_synt_2 GDP_Man_Dehyd CFIA_Pcf11
Other DBs
NCBI-GeneID: 4840080
NCBI-ProteinID: XP_001385417
JGI: 68020
UniProt: A3LX21
Position
6:353493..357715
AA seq 1394 aa
MSFWSEYLDSPTLSVLPHDFLKPANNQSVEATYSFEIEKEESFITGLAVFSALIYRLTGD
EDIVIATDAKTSGTEFIIRLSLTPELSFDQLVANVTKEFENNVAKIDYTSLSEVSEQIRA
AKKLEEHPGLFRLSYQHSNPNQQLSTTVEGSIRDLAVFTEGNKFTIFYNSLLYKHDRVVV
FGEQFSQYIAKASSNSNVQITKVNLITPSQKEHLPDPTLDLDWGGYRGAIQDIFMKNALA
HPEKPCVIETKSFLDPSTKTRTFNYKQINQASNVVGNYLKETGIKKGDIVMIYAYRGVDL
MVAVMGVLKAGATFSVIDPAYPPARQNIYLSVAKPSGLIGLEKAGTLDSLVVDYIKNELK
VVTTIPQLKINDDGSLVGGVIEGQSADCLQGYEKFQDQATGVIVGPDSNPTLSFTSGSEG
IPKGVLGRHYSLAYYFPWMAKTFGLSEKDKFTMLSGIAHDPIQRDMFTPLFLGAQLLVPT
ADDIGTPGKLADWMAEYGATVTHLTPAMGQLLSAQASTPIPSLHHAFFVGDILTKRDCLR
LQTLAENVFIVNMYGTTETQRSVSFFEIKSRKADSTYLKNLKDVMPAGTGMYNVQLLVVN
RNDRSQTCGVGEVGEIYVRAAGLAEGYRGLPDLNKEKFVTNWYVDSSEWVKKDEENKKPE
EVWREHGWLGPRDRLYRTGDLGRYLPDGNVECCGRADDQVKIRGFRIELGEIDTHLSQHP
LVRENVTLVRRDKNEEPTLISYIVPKESPELAQFKAEVDDETDSDPIVQGLVSYRELIKD
IKNYLKKRLASYAVPTVVVPLAKLPLNPNGKVDKPKLPFPDTAQLSAVAKLVASSRAGGA
EAAEEEEFSKLEEVIRDLWLEVLPTRPATISKDDSFFDLGGHSILGTRMIFELRKRLNVD
VPLGVIFKNPSIEAFAKEVEKFIKGSDFQLADGKETEEEAEEIIDYSKDAAELAQSALLE
KYDSLKELDTSKTINVFVTGGTGFLGSFIIRDILTSRPNQSFKIYAHVRASSKEAGLERL
RKAGLTYGIWQDEWSKNIEVVLGDLSKPQFGLDDTDWVQLANEIDVIVHNGAFVHWVYPY
SQLRDANVNGTINVLNLCGQGKAKFFSFVSSTSALDTDYFVHLSDELIAKGLPGLPESDN
LQGSAKGLGNGYGQSKWAAEYIIRAAGKRGLRGCITRPGYVTGFSQTGASNTDDFLLRML
KGSAELGFYPNISNNVNMVPVDHVARVVVATALHPPVDTELAVAHVTGHPRIEFNDFLGT
LKTYGYNVDIVDYPEWRKELERFVVEDSKESALFPLLHFVLDNLPQDTKAPELDDSNAAT
SLKADAAWTGVDFSSGRGVDAKQMSIYISYLIKTGFLPVPTGEGAKLPQIEISKVTLDLI
NSGASARSSAAAPK
NT seq 4185 nt   +upstreamnt  +downstreamnt
atgtctttctggtcagagtatttggatagtccaactttgtctgtgttaccacatgacttc
ttgaagcctgccaataaccagtcggtcgaggctacctatagttttgaaattgaaaaggaa
gagagctttattactggacttgctgtcttttctgcattaatctacagattgactggagac
gaggacatagtcattgctacagatgcgaagacttcaggaactgagttcatcatcagattg
agtttgacaccagagttgagttttgatcaattagttgctaatgtcaccaaggaattcgaa
aataatgttgccaagattgactacacttctctttcggaggtatcagaacagataagagct
gctaagaaattggaagaacatccaggcttgttcaggttatcatatcagcactcgaatcct
aaccaacagctatccaccactgttgagggctccattcgtgatttggctgtattcacagaa
ggcaacaagttcaccattttctacaacagtttgctctataagcatgacagagttgttgta
tttggagaacagttttcgcaatacattgctaaagcttcctccaattcaaatgttcagatt
acaaaggttaacttgatcactccatctcagaaggaacatttgccagatccaactttggac
ttggactggggcggataccgtggagccatccaagacatcttcatgaagaatgccttagca
catccagaaaaaccatgtgtgattgaaaccaagtcgttcttggatccttctacaaagact
cgaaccttcaactacaaacaaatcaatcaggcttccaacgtagtaggtaactatttgaag
gaaactggtatcaagaaaggagatatagtcatgatctacgcttacagaggtgttgatttg
atggtagctgtgatgggtgtcttgaaggctggtgccaccttttctgtgattgaccctgcc
taccctccagctagacaaaatatctacctctctgtagccaagccttctgggttaattggg
ttggaaaaggctgggaccttagactcattagttgtggattacatcaaaaacgagttgaag
gtagttaccacaattcctcaattgaaaatcaacgatgacggttcattggtcggaggtgtg
attgaaggccaatccgctgattgtttacaaggctacgaaaagttccaagatcaggctaca
ggagtcattgttggtcctgattccaatcctactctttcattcacttctggttctgaaggt
attcccaagggtgttttgggtcgtcattactctttggcttactatttcccatggatggca
aagacttttggattgtctgaaaaggacaagtttaccatgttgtctggtattgctcatgat
ccaatccaaagagatatgttcacgcctttatttttgggggctcaattgttggtgcccact
gcagacgatattggaactccaggtaaattggcagattggatggctgaatatggtgctact
gtaactcatttgacaccagctatgggtcaattgttgagcgctcaagcttctacaccaatt
ccaagtttgcatcatgccttctttgttggtgatattttgacgaagagagactgtttgaga
ttgcaaactttggcagaaaacgtttttattgtaaatatgtacggtactactgaaactcaa
aggtcggtgtccttcttcgagattaagagcagaaaggctgattcaacttacttgaagaac
ttaaaggatgtcatgccagcaggtaccggtatgtacaatgtccagttgctagttgtcaac
agaaatgacagatcgcaaacttgtggtgttggtgaagtaggagaaatctacgttagagca
gctggacttgccgaagggtacagagggttgccagacttgaacaaagaaaagtttgttact
aactggtatgttgattctagcgaatgggttaagaaagacgaggaaaacaagaagccagaa
gaagtatggagagaacacggatggttgggtccaagagacagattgtacagaactggagat
ttaggacgttatcttccagatggtaatgttgaatgttgtggtcgtgctgacgatcaagtc
aagatcagagggttcagaattgaattgggagaaatcgacacccacttgtcacaacatccc
ttggtcagggagaacgttactttggttagaagagacaaaaacgaagaaccaacattgatt
tcatatatagttcccaaagagtctcccgaattggctcaatttaaggctgaagtggacgat
gaaaccgactctgatcctattgttcaaggtttagtttcctacagagaattgataaaggac
atcaagaactacttgaagaagagattggcatcttatgctgtgccaactgtagtggttcct
cttgctaaattgcctttgaaccctaacggtaaggtggacaagccaaaattgccattccca
gatacggcacaattgtcagctgtggccaaattggttgccagcagtagagctggtggagct
gaagccgccgaagaagaagaattctctaagttagaagaagttatcagagatttgtggtta
gaggttttgcccaccagaccagcaacgatttccaaggacgactcgttctttgacttgggt
ggtcactccatcttgggtactagaatgatttttgaattgagaaagagattgaatgtcgat
gttccattgggtgttatctttaagaacccttctattgaagcttttgccaaggaagtggaa
aagtttattaagggttccgactttcaactagctgatggcaaggaaactgaagaagaagcc
gaagaaattatcgactattccaaagacgctgctgagttggctcaaagtgcattgcttgaa
aaatacgactcgttgaaggagcttgatacatcgaagacaatcaacgtgttcgtcactggt
ggtactggtttcttgggctctttcatcatacgcgatatcttgacgtctcgtccaaaccaa
tcttttaagatctacgctcatgtcagagcttcttccaaagaagcaggtctcgaaaggtta
cgcaaggctggtcttacttacggtatttggcaagacgaatggtcaaagaatatcgaggtg
gtattgggtgatttgtccaagccgcagtttggtttggacgatactgattgggtacaatta
gcaaacgaaatcgatgtcatagttcataacggtgcttttgttcactgggtgtatccatac
tctcaattgagagatgccaatgtcaatggcaccattaacgttttgaacttgtgtggtcaa
ggtaaggctaagttcttttcgttcgtttcttctacatctgctcttgacacagactacttt
gtccacctttccgacgaattgattgctaagggcttgcctggtcttccagaatccgataat
ttacaaggttccgccaagggcttgggcaatggttatggtcaatccaaatgggctgccgaa
tatattatcagagctgctggtaagagaggattgagaggttgtatcacgagaccaggttac
gtaactggcttttcgcagactggtgcttccaacactgatgatttcttgttgagaatgtta
aagggaagtgctgaattgggattctaccccaacatttcaaacaatgtcaacatggttcca
gtagaccatgttgccagagtagtcgtagcaacagcattgcatcctcctgtagacactgaa
ttggctgtagctcatgtcactggacatccaagaatcgaatttaatgatttcttgggtact
ttgaagacctatggatacaatgtcgatatcgtcgactaccctgaatggagaaaggagcta
gaaagatttgtagtggaagactcgaaggaatctgctttgttcccattgttgcactttgtt
ttggacaacttgccacaggataccaaggctccagaattggacgattccaacgctgccact
tctttgaaagctgatgctgcctggactggagtcgatttcagttctggaaggggtgtggac
gctaagcagatgagcatctacatcagttacttgatcaagactggcttcttgcctgtacct
actggtgaaggtgcaaagttgcctcaaattgaaattagcaaagtgaccttggacttgatt
aattctggagccagcgcccgttcttcggctgctgcacctaagtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   JGI (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (9)   
   Pfam (9)   
All databases (41)   

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