KEGG   Pseudodesulfovibrio profundus: DPRO_0148
Entry
DPRO_0148         CDS       T05258                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
pprf  Pseudodesulfovibrio profundus
Pathway
pprf00290  Valine, leucine and isoleucine biosynthesis
pprf00620  Pyruvate metabolism
pprf01100  Metabolic pathways
pprf01110  Biosynthesis of secondary metabolites
pprf01210  2-Oxocarboxylic acid metabolism
pprf01230  Biosynthesis of amino acids
Module
pprf_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:pprf00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    DPRO_0148 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    DPRO_0148 (leuA)
Enzymes [BR:pprf01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     DPRO_0148 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: SOB57027
UniProt: A0A2C8F4K2
Position
DPRO:149349..150884
AA seq 511 aa
MADRVYVFDTTLRDGEQSPGATMNLDEKIRMARQLETLGVDVIEAGFPIASQGDFEAVQA
IARAVESVQVAGLCRAVTGDIDRCWEAIKEARNPRIHTFLATSDIHMKYKLGKEPEQVVE
MIDKAVRHAKSYTQNVEFSAEDASRSDWDFLVRVTETAIEAGATVVNIPDTVGYTQPFEY
YDMIKYLMDNVRNIDDAIISVHCHNDLGSAVANSLAAIKAGARQVECTVLGIGERAGNAA
LEDLVMAINTRKELYDVETNVVTEQLYPSCRRLSQIIGMPIPPNKAIVGANAFAHESGIH
QDGVIKNRLTYEIMTPDSIGRTSNDIVIGKHSGSHAVKNKAEELGYVLDPDQVKTLFQAV
KDLADRKEQVFDEDVEALILESVYRRRDKFRLIDMSVFCGTGDVPAHAATVMEFGEEGED
VEVRKNSSFGEGSIDAVFQSIYSLVGVAPKLEVYSVNAVTEGSDALAGVAVRIEHDGVKA
VGRANDGDVVKASALAMINALNRLEKTKEEK
NT seq 1536 nt   +upstreamnt  +downstreamnt
atggctgatagagtgtatgtttttgataccacgttgcgtgatggtgaacagtctcctggt
gcaaccatgaacctggatgagaaaatccggatggcccgccagttggaaacccttggtgtt
gatgtgatcgaggctggatttcccattgccagtcaaggggatttcgaggctgttcaggcg
attgcacgggctgtggaatcggtgcaggtggcaggtttgtgccgtgccgttaccggtgac
atcgaccgttgctgggaggccatcaaagaggctcgtaaccccagaattcacacgttcctg
gctaccagcgacattcatatgaaatataaactgggtaaggagcctgagcaggtggtcgag
atgatcgacaaagccgttcgacatgctaaatcctacacccagaatgtagagttctcggct
gaggatgcctcacgttcggattgggatttcctcgtcagggtgacagagaccgcaattgaa
gcgggagcaacggttgttaacatccctgacactgtcggctacacccagcccttcgaatac
tacgatatgatcaagtacctgatggataatgtacgcaacattgatgatgcgatcatatcc
gttcattgtcataatgatcttgggtcagcggtagccaacagtctcgccgccatcaaggcc
ggtgctcgtcaggtggaatgcaccgtgttgggaattggtgagcgtgcaggtaatgctgca
ctggaagatctcgtcatggccatcaatacgcgcaaggaactctatgacgttgagaccaat
gtcgtaaccgagcaattgtatccttcctgccgtcgtctgtcgcaaattatcggcatgccg
attccgcctaacaaggctattgtcggcgccaatgcgttcgcccatgaatccggtattcat
caggatggtgtgatcaagaatcgtttgacctacgaaatcatgacgcctgattcaatcgga
aggacttccaatgatatcgtcattggaaagcattccggttcgcatgcggtcaagaataag
gccgaagagttgggttacgtgcttgatcctgatcaggtcaaaacattgttccaggctgtt
aaggacttggccgatcgcaaggagcaggtctttgatgaggatgtggaagcacttattttg
gagagtgtctatcgtcgtcgcgacaagttccgtttgatcgacatgtctgttttctgcggt
acaggggatgttcctgcccatgcagcgactgtcatggagtttggagaggaaggcgaggat
gttgaggtgaggaagaacagctcctttggtgaaggttccattgacgctgtattccagtcc
atttattcattggtgggagtcgctcccaaattggaagtttactcggttaatgcggtcact
gaaggttccgacgccctggccggtgtcgctgttcgcattgagcacgatggagtgaaggct
gtgggccgagccaacgatggtgacgtggtgaaagcaagcgcgttggccatgattaacgca
ttgaaccgtttggaaaaaacgaaagaggagaagtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (23)   

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