KEGG   Pan paniscus (bonobo): 100979621
Entry
100979621         CDS       T02283                                 
Symbol
GCK
Name
(RefSeq) hexokinase-4 isoform X2
  KO
K12407  glucokinase [EC:2.7.1.2]
Organism
pps  Pan paniscus (bonobo)
Pathway
pps00010  Glycolysis / Gluconeogenesis
pps00052  Galactose metabolism
pps00500  Starch and sucrose metabolism
pps00520  Amino sugar and nucleotide sugar metabolism
pps00524  Neomycin, kanamycin and gentamicin biosynthesis
pps01100  Metabolic pathways
pps01200  Carbon metabolism
pps01250  Biosynthesis of nucleotide sugars
pps04910  Insulin signaling pathway
pps04911  Insulin secretion
pps04917  Prolactin signaling pathway
pps04922  Glucagon signaling pathway
pps04930  Type II diabetes mellitus
pps04950  Maturity onset diabetes of the young
pps05230  Central carbon metabolism in cancer
Module
pps_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
pps_M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose
pps_M00892  UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc
Brite
KEGG Orthology (KO) [BR:pps00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    100979621 (GCK)
   00052 Galactose metabolism
    100979621 (GCK)
   00500 Starch and sucrose metabolism
    100979621 (GCK)
   00520 Amino sugar and nucleotide sugar metabolism
    100979621 (GCK)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    100979621 (GCK)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    100979621 (GCK)
   04910 Insulin signaling pathway
    100979621 (GCK)
   04922 Glucagon signaling pathway
    100979621 (GCK)
   04917 Prolactin signaling pathway
    100979621 (GCK)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    100979621 (GCK)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    100979621 (GCK)
   04950 Maturity onset diabetes of the young
    100979621 (GCK)
Enzymes [BR:pps01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     100979621 (GCK)
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1
Other DBs
NCBI-GeneID: 100979621
NCBI-ProteinID: XP_003805278
Ensembl: ENSPPAG00000030131
Position
7:complement(44857604..44903683)
AA seq 465 aa
MLDDRARMEAAKKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPT
YVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAE
MLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNN
VVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQN
VELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGE
LVRLVLLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPS
TTDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFK
ERFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACKKACMLGQ
NT seq 1398 nt   +upstreamnt  +downstreamnt
atgctggacgacagagccaggatggaggccgccaagaaggagaaggtagagcagatcctg
gcagagttccagctgcaggaggaggacctgaagaaggtgatgagacggatgcagaaggag
atggaccgtggcctgaggctggagacccatgaagaggccagtgtgaagatgctgcccacc
tacgtgcgctccaccccagaaggctcagaagtcggggacttcctctccctggacctgggt
ggcactaacttcagggtgatgctggtgaaggtgggagaaggtgaggaggggcagtggagc
gtgaagaccaaacaccagatgtactccatccccgaggacgccatgaccggcactgctgag
atgctcttcgactacatctctgagtgcatctccgacttcctggacaagcatcagatgaag
cacaagaagctgcccctgggcttcaccttctcctttcctgtgaggcacgaagacatcgat
aagggcatccttctcaactggaccaagggcttcaaggcctcaggagcagaagggaacaat
gtcgtggggcttctgcgagacgctatcaaacggagaggggactttgaaatggatgtggtg
gcaatggtgaatgacacggtggccacgatgatctcctgctactacgaagaccatcagtgc
gaggtcggcatgatcgtgggcacgggctgcaatgcctgctacatggaggagatgcagaat
gtggagctggtggagggggacgagggccgcatgtgcgtcaataccgagtggggcgccttc
ggggactctggcgagctggacgagttcctgctggagtatgaccgcctggtggacgagagc
tctgcaaaccccggtcagcagctgtatgagaagctcataggtggcaagtacatgggcgag
ctggtgcggctcgtgctgctcaggctcgtggacgaaaacctgctcttccacggggaggcc
tccgagcagctgcgcacacgcggagccttcgagacgcgcttcgtgtcgcaggtggagagc
gacacgggcgaccgcaagcagatctacaacatcctgagcacgctggggctgcgaccctcg
accaccgactgcgacatcgtgcgccgcgcctgcgagagcgtgtctacgcgcgctgcgcac
atgtgctcggcggggctggcgggcgtcatcaaccgcatgcgcgagagccgcagcgaggac
gtaatgcgcatcactgtgggcgtggatggctccgtgtacaagctgcaccccagcttcaag
gagcggttccatgccagcgtgcgcaggctgacgcccagctgcgagatcaccttcatcgag
tcggaggagggcagtggccggggtgcggccctggtctcggcggtggcctgtaagaaggcc
tgtatgctgggccagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (18)   
   KEGG PATHWAY (15)   
   KEGG MODULE (3)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (2)   
   Pfam (2)   
All databases (46)   

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