KEGG   Poecilia reticulata (guppy): 103465638
Entry
103465638         CDS       T05149                                 
Symbol
cftr
Name
(RefSeq) cystic fibrosis transmembrane conductance regulator
  KO
K05031  cystic fibrosis transmembrane conductance regulator [EC:5.6.1.6]
Organism
pret  Poecilia reticulata (guppy)
Pathway
pret02010  ABC transporters
pret04530  Tight junction
Brite
KEGG Orthology (KO) [BR:pret00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    103465638 (cftr)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    103465638 (cftr)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:pret02000]
    103465638 (cftr)
Enzymes [BR:pret01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.1  Enzymes altering polypeptide conformation or assembly
    5.6.1.6  channel-conductance-controlling ATPase
     103465638 (cftr)
Transporters [BR:pret02000]
 ABC transporters, eukaryotic type
  ABCC (CFTR/MRP) subfamily
   ABCC7 subgroup
    103465638 (cftr)
SSDB
Motif
Pfam: CFTR_R ABC_membrane ABC_tran AAA_21 AAA_16 SMC_N AAA_29 DUF87 RsgA_GTPase MMR_HSR1 T2SSE MeaB AAA_23
Other DBs
NCBI-GeneID: 103465638
NCBI-ProteinID: XP_008408875
UniProt: A0A3P9N2D0
Position
LG6:complement(905370..951213)
AA seq 1502 aa
MQKSPVEDANFFSRFVFWWISPLLRKGFTKKLELADVYKAPSFDLADTLSERLEREWDKE
VVLAKGRPKLLKALARCFFLPFAFFGVLLFFGEASKTVQPQLSGRIIASFDPLHAPERSQ
GYYLALGLGLLFTARFILLQPALYGLHHLGMQIRIALFSLIYKKTLKLSSRVLDKISTGQ
LVSLMSAHLNKLDESLGLAHFVWITPLQCILCTGLIWELIEVNGFCALATLTLLGIFQAW
LSLKMGPPRAKRAGLINRRLALTSEIVENIHSVKAYGWEEVMETIIKNIRQDEMTLTRKI
GSLRYFYSASYFFSAILVIISAIVPHALSKGMILRPIFTTASYCVVLRMTLTRQLPGSIQ
MWYDTLALVKKIEDFLLKEEYKVMDYSLTTVGLELINVSASWDEGIVALFEKIKRENKAN
GHMTGDDGLFFTNLYITPVLKNINLRLEEGMMLGVAGSTGSGKSSLLMMILGELVPSEGK
IRHSGRVSYSPQTSWIMPGTIRDNILFGLTYDEFRYASIIKACQLEEDFDLLPEKDKTPI
AEGGVTLSGGQRARICLARAVYKDADLYLLDAPFTHLDIATEKEIFDKCVCKLMASKTRV
VVTSKLEHLKRADRILLLHNGDCYFYGTFSELQAQRPDFSSLLLGLEAYDNINAERRGSI
LTETLRRVSVDETANFRGPDPNRQSFRHVPSHSHAMGDGYPEKRKPSLILNPLTAARKFS
FIGNSQQNNFQSTSMDDGVHELSERRFSVVPEDDQVEEVLPRSDMYHHGLQHLNGRRQSV
LAFITNAQGQERREQMQSSFRKKLSITPQCNLASELDIYARRLSKDSVFDISEEVDEEDM
EECFADEREKIFETTSWSTYLRYISTNRSLIYVLIFIVIVFVIEVAGCVIGIFLVTDKIW
KDGPNLNSPNHIDDQHPNASSPPVHVAVIVTQNSAYYIIYLFFTHSDSILALGVFRGLPL
VHTLLTVSKRLHEQMLSSVLRAPMSVLNTMKTGRIMNRFTKDMAVIDDMLPLVLFDLIQL
TLLVIGCIFTVSIMRPYIFISAIPLAVVFVVIRKYFLRTGQQLKQLEAEARSPIFSHLII
SLKGLWTIRAFGRQTYFETLFHKALNTHTSTWFHYLSSLRWFLFRCDVIFVLFFTVAAFI
AVGTNKDRPGEIGIIVALAMLILGTFQWAIITSINVDGLMRSVDRVFKFIDLASEETFQG
KPGGKGGSDLVINNPSAYSYWPNRGQLYVQGLTVKYTEAGRAVLNDISFAVEGGQSVGLL
GRTGSGKSTLLSALLRLAYTEGEMFIDGVSSSSIPLQTWRKAFGVVPQKVFILTGTFRMN
LDPYGRYSDDELWQVAEEVGLKSVIEQFPDKLDFELKDGGSVLSNGHKQLMCLARSILSK
ACILLLDEPSSYLDPITLQVLRKTLKQSFSNCTVILSEHKVEPLLECQSFLMIEKSSVKS
YDTIQKLMNEMSHLKQAISPADRLRIFPTPHRLNSIKRPPPQTTKISSLPEEAEDEIQDT
RL
NT seq 4509 nt   +upstreamnt  +downstreamnt
atgcagaagtcaccggtggaagatgcaaacttcttctctagatttgtcttttggtggata
tctcctctactgaggaaaggtttcactaagaagttggagctggctgacgtctacaaggct
ccctcgtttgatctggcagacaccctctccgagagacttgaaagggaatgggacaaagag
gtggtgctggccaaaggcaggcccaagttgctgaaagcactggcgcgatgctttttcctg
ccgttcgccttcttcggtgtcctcctcttcttcggggaggcatccaagactgtgcagcct
cagctttcaggtcgcatcattgcttcctttgaccccttgcatgctccggagcgaagtcag
gggtactacctggccctggggcttggcctcctcttcactgctcgcttcatcctgctgcag
cccgcgctctacggcctgcatcacctcggtatgcagattcgcattgccctcttcagcctc
atatacaaaaagacactcaagctgtccagtagggtgttggataagatcagcaccgggcag
ctcgtcagtctcatgtctgcccatctcaacaagctggatgagagcctcggtctagcacac
tttgtgtggatcacccctctgcaatgtatcctgtgtactggtttgatctgggagctgatc
gaggtgaatggcttctgtgccctggcaactctcactcttcttggcattttccaagcgtgg
ctgtccttgaagatgggacctcctagggcgaaacgtgccgggctcataaaccgacgtctg
gctcttacttctgagattgtggagaacattcactcggtgaaggcgtacggctgggaggaa
gtgatggaaaccatcatcaaaaacatcagacaggatgaaatgactttaaccagaaagatt
ggctctctacgctatttctacagtgcttcatattttttctctgccatactggttatcata
tcggccatcgtgccacatgcactcagtaaaggcatgatactgcggccgattttcaccaca
gcatcatactgtgttgtgctacgcatgacactcacccgccagctgccaggctccatccag
atgtggtacgacacactggcactggtcaagaagatcgaggatttcctgcttaaggaagaa
tacaaagtaatggattacagtttgaccacagttggattggagctgatcaatgtctctgca
tcctgggatgagggtattgttgcgctctttgagaagatcaagcgggagaacaaagcaaat
ggacacatgaccggtgacgatggactgttcttcactaacttatacatcacacctgtcctc
aaaaacatcaacctacgcttagaggaaggcatgatgctcggagtggctggatctactggg
tctggaaagagttccctcctcatgatgatcctgggagagctggtgccatcagagggcaaa
attagacacagcggtcgggtttcgtattcaccgcagacttcttggataatgccagggacc
attcgtgacaacatccttttcggcctgacgtatgacgaatttcgctacgcttccatcatt
aaggcctgccagctggaagaggattttgacttgctgcctgagaaagataagacgcccatt
gctgagggaggggttacccttagtggaggtcaaagagcaaggatctgcctcgccagggcc
gtatataaagatgcagacctgtacctgctcgatgcacctttcacccacctggacattgca
acagagaaagagatctttgacaaatgtgtctgtaaactgatggcctccaagactcgcgtt
gtggtcaccagcaagttggagcacctgaagcgggcggatcgaatccttctgttgcacaac
ggagactgctacttctacggcaccttctcagagcttcaagcgcagcggccagacttcagc
tccctgctgcttggtctcgaagcttatgacaacatcaacgcggagcggcgcggctccatt
ctcacggaaactcttcgcagagtctccgtggatgaaacagcaaatttccgaggcccagac
cccaatcgccaatccttccgccacgtgccgtctcacagccacgccatgggcgacggctat
cccgaaaaacgcaagccgtcactcatcctcaaccctctcacagctgcccgcaagttttca
ttcattgggaactcccagcagaataacttccagtccacatccatggacgatggggtgcat
gaactttcagagagaagattctcagtggtgcctgaggacgatcaggtcgaagaggtgctt
ccacggagtgacatgtatcaccacgggctgcagcacctcaatggcaggcgccagtctgtt
ctggcgttcatcaccaatgctcagggtcaggagcgcagagagcagatgcagtcgtccttc
agaaaaaagttgtccatcaccccgcagtgcaacctagcgtccgagctggacatctacgcc
cggcgcctgtccaaggacagtgtgtttgacataagtgaggaagtggatgaagaagacatg
gaggaatgctttgcagatgaacgtgagaagatattcgaaactacctcatggagtacttat
ctacgctacatttccaccaataggagtttaatctatgtcctaattttcattgtgattgtc
tttgtcattgaggttgctggttgtgtcattggcatttttctcgttactgataagatatgg
aaggatggtcccaacctgaattcaccaaaccacatcgatgatcagcaccctaatgcatca
tcgcctcctgtccacgtcgccgtcatagtcacacaaaacagcgcctactacatcatctac
ttattctttactcactcagacagcatactggcccttggagtcttcaggggcctcccttta
gtccacacgttgctcactgtgtctaaaagacttcacgaacagatgcttagctctgtgcta
cgggcccccatgtctgttcttaacaccatgaaaacaggccggataatgaacagattcacc
aaggacatggccgtcattgatgacatgctacctctagtgctgtttgacctcatacagtta
actttacttgtcattgggtgcatcttcactgtgtccatcatgagaccatacatctttata
tctgcaatcccactggctgttgtctttgtggtcatcaggaagtacttcttacgaacagga
caacaactcaaacagctagaggctgaagctcgtagtcccatcttctctcacctcatcatt
tcactgaagggtttatggacaattcgagcttttggacgtcagacttacttcgagactcta
ttccacaaagctctgaacacccacacatccacctggttccactacctgtcctcgctgaga
tggttcctgttccgctgcgatgtgatctttgtgttgtttttcaccgttgctgccttcatc
gccgtaggaaccaacaaggacagacctggagagattggcatcattgtggccctggccatg
ctcatcctgggcactttccaatgggctatcatcaccagtatcaatgtggacggcctgatg
cgttcagtggaccgagtgttcaaattcatcgacttggcatcagaagagaccttccaagga
aagcctggaggaaaaggaggttctgatcttgtcatcaacaacccaagcgcgtacagctac
tggcctaaccgcggccagctgtatgtccagggtctcaccgtcaaatacacagaagctggg
cgggccgtgctcaacgatatctccttcgctgtggaggggggtcagagtgtgggtctgctg
ggtcggaccgggtctgggaagagtaccctgctgtccgctctgctgcgcctcgcctacacc
gaaggggaaatgttcatcgacggagtttcttccagctccatccccttgcaaacatggagg
aaggcctttggagtggtgccgcagaaagtcttcattctgactggaaccttccggatgaac
ctggacccgtacggtcgttacagtgacgatgagctgtggcaggtggctgaggaggttggg
ttgaaatcggtcatcgagcagttccccgataagctggactttgagctgaaggacggcggc
agcgttctgagcaacggccacaaacagctgatgtgtctggcccgctccatcctcagcaag
gcctgcatcctgctgctggacgagccgtcctcctacctggaccccataacactgcaggtc
ctgagaaagacgttgaagcagtcgttttccaactgcaccgtcatcctgtccgaacacaaa
gtggagccgctgctggagtgccagtcgttcctgatgattgagaagagctctgtgaaaagc
tacgacaccattcagaaacttatgaacgaaatgagtcacctgaaacaggccatcagcccc
gccgacaggctccgaatcttccccaccccccatcgcctcaactccatcaagagaccgcca
cctcagaccaccaagatctcgtcgctaccagaggaagccgaggacgaaatccaggacaca
cggctttaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (13)   
   Pfam (13)   
All databases (27)   

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