KEGG   Panthera tigris altaica (Amur tiger): 102949732
Entry
102949732         CDS       T02988                                 
Symbol
ADCY2
Name
(RefSeq) adenylate cyclase 2
  KO
K08042  adenylate cyclase 2 [EC:4.6.1.1]
Organism
ptg  Panthera tigris altaica (Amur tiger)
Pathway
ptg00230  Purine metabolism
ptg01100  Metabolic pathways
ptg01522  Endocrine resistance
ptg04015  Rap1 signaling pathway
ptg04020  Calcium signaling pathway
ptg04022  cGMP-PKG signaling pathway
ptg04024  cAMP signaling pathway
ptg04062  Chemokine signaling pathway
ptg04072  Phospholipase D signaling pathway
ptg04114  Oocyte meiosis
ptg04211  Longevity regulating pathway
ptg04213  Longevity regulating pathway - multiple species
ptg04261  Adrenergic signaling in cardiomyocytes
ptg04270  Vascular smooth muscle contraction
ptg04371  Apelin signaling pathway
ptg04540  Gap junction
ptg04611  Platelet activation
ptg04713  Circadian entrainment
ptg04714  Thermogenesis
ptg04723  Retrograde endocannabinoid signaling
ptg04724  Glutamatergic synapse
ptg04725  Cholinergic synapse
ptg04727  GABAergic synapse
ptg04750  Inflammatory mediator regulation of TRP channels
ptg04911  Insulin secretion
ptg04912  GnRH signaling pathway
ptg04913  Ovarian steroidogenesis
ptg04914  Progesterone-mediated oocyte maturation
ptg04915  Estrogen signaling pathway
ptg04916  Melanogenesis
ptg04918  Thyroid hormone synthesis
ptg04921  Oxytocin signaling pathway
ptg04922  Glucagon signaling pathway
ptg04923  Regulation of lipolysis in adipocytes
ptg04925  Aldosterone synthesis and secretion
ptg04926  Relaxin signaling pathway
ptg04927  Cortisol synthesis and secretion
ptg04928  Parathyroid hormone synthesis, secretion and action
ptg04934  Cushing syndrome
ptg04935  Growth hormone synthesis, secretion and action
ptg04970  Salivary secretion
ptg04971  Gastric acid secretion
ptg04972  Pancreatic secretion
ptg04976  Bile secretion
ptg05032  Morphine addiction
ptg05163  Human cytomegalovirus infection
ptg05166  Human T-cell leukemia virus 1 infection
ptg05200  Pathways in cancer
ptg05207  Chemical carcinogenesis - receptor activation
ptg05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ptg00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    102949732 (ADCY2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    102949732 (ADCY2)
   04371 Apelin signaling pathway
    102949732 (ADCY2)
   04020 Calcium signaling pathway
    102949732 (ADCY2)
   04072 Phospholipase D signaling pathway
    102949732 (ADCY2)
   04024 cAMP signaling pathway
    102949732 (ADCY2)
   04022 cGMP-PKG signaling pathway
    102949732 (ADCY2)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    102949732 (ADCY2)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    102949732 (ADCY2)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102949732 (ADCY2)
   04062 Chemokine signaling pathway
    102949732 (ADCY2)
  09152 Endocrine system
   04911 Insulin secretion
    102949732 (ADCY2)
   04922 Glucagon signaling pathway
    102949732 (ADCY2)
   04923 Regulation of lipolysis in adipocytes
    102949732 (ADCY2)
   04912 GnRH signaling pathway
    102949732 (ADCY2)
   04913 Ovarian steroidogenesis
    102949732 (ADCY2)
   04915 Estrogen signaling pathway
    102949732 (ADCY2)
   04914 Progesterone-mediated oocyte maturation
    102949732 (ADCY2)
   04921 Oxytocin signaling pathway
    102949732 (ADCY2)
   04926 Relaxin signaling pathway
    102949732 (ADCY2)
   04935 Growth hormone synthesis, secretion and action
    102949732 (ADCY2)
   04918 Thyroid hormone synthesis
    102949732 (ADCY2)
   04928 Parathyroid hormone synthesis, secretion and action
    102949732 (ADCY2)
   04916 Melanogenesis
    102949732 (ADCY2)
   04925 Aldosterone synthesis and secretion
    102949732 (ADCY2)
   04927 Cortisol synthesis and secretion
    102949732 (ADCY2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102949732 (ADCY2)
   04270 Vascular smooth muscle contraction
    102949732 (ADCY2)
  09154 Digestive system
   04970 Salivary secretion
    102949732 (ADCY2)
   04971 Gastric acid secretion
    102949732 (ADCY2)
   04972 Pancreatic secretion
    102949732 (ADCY2)
   04976 Bile secretion
    102949732 (ADCY2)
  09156 Nervous system
   04724 Glutamatergic synapse
    102949732 (ADCY2)
   04727 GABAergic synapse
    102949732 (ADCY2)
   04725 Cholinergic synapse
    102949732 (ADCY2)
   04723 Retrograde endocannabinoid signaling
    102949732 (ADCY2)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102949732 (ADCY2)
  09149 Aging
   04211 Longevity regulating pathway
    102949732 (ADCY2)
   04213 Longevity regulating pathway - multiple species
    102949732 (ADCY2)
  09159 Environmental adaptation
   04713 Circadian entrainment
    102949732 (ADCY2)
   04714 Thermogenesis
    102949732 (ADCY2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102949732 (ADCY2)
   05207 Chemical carcinogenesis - receptor activation
    102949732 (ADCY2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102949732 (ADCY2)
   05163 Human cytomegalovirus infection
    102949732 (ADCY2)
  09165 Substance dependence
   05032 Morphine addiction
    102949732 (ADCY2)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    102949732 (ADCY2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    102949732 (ADCY2)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102949732 (ADCY2)
Enzymes [BR:ptg01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     102949732 (ADCY2)
SSDB
Motif
Pfam: Guanylate_cyc Adcy_cons_dom AC_N HNOBA
Other DBs
NCBI-GeneID: 102949732
NCBI-ProteinID: XP_007090688
Position
Un
AA seq 1056 aa
MHLQFPQSACNRRSVINVTRFAEPVQTEERGSRLKSEVEDHVAFLITVPTALAIFFAIFI
LVCIESVFKKLLRLFSLVIWMCLVAMGYLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFN
MRDAIIASVLTASSHTVVLSICLSATPGAKEHLVWQILANVIIFICGNLAGAYHKHLMEL
ALQQTYQDTCNCIKSRIKLEFEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMEN
TNNFHNLYVKRHTNVSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRI
KILGDCYYCVSGLPISLPNHAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCG
VIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHISSVTLEHLNGAYKVEEGDGDIRDPYLK
QHLVKTYFVINPKGERRSPHLFRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDS
MTTENGKISTTDVPMGQHNFQNRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSED
IQRISLLFYNKILEKEYRATALPAFKYYVTCACLILFCIFIVQILVLPKTSILGISFGAA
FLLLACILFVCFAGQLLQCSKKASASLLWLLKSSSIIADRPWPRVSLTVLTTAIILTMAV
FNMFFLSDPEEAMPPTANTSNTSLSALNNQAVILRAQNLFFLPYFIYSCILGLISCSVFL
RVNYELKMLIMMAALIGYNTILLHTHAHVLDDYSQVLFERPGIWKDLKTMGSVSLFIFFI
TLLVLGRQNEYYCRLDFLWKNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKN
EELYHQSYDCVCVMFASIPDFKEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGV
EKIKTIGSTYMAATGLSAVPSQEHTQEPERQYMHIGTMVEFAFALVGKLDAINKHSFNDF
KLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSLILQTLGY
TCTCRGIINVKGKGELKTYFVNTEMSRSLSQSNVAS
NT seq 3171 nt   +upstreamnt  +downstreamnt
atgcacctgcagtttccccagagcgcatgtaatcgccgatcggtcatcaacgtgacgcgc
tttgcagaacccgtgcagactgaagagcgtggcagccgtctgaagagtgaagtcgaagac
catgtggcgtttttaataacagtcccaactgccctggcgatcttctttgcgatattcatc
ctcgtgtgcatcgagtccgtgtttaagaagctgctacgccttttctctttggtgatatgg
atgtgtctggtggccatggggtacttgttcatgtgctttggaggcaccgtctccccctgg
gaccaggtgtccttcttcctcttcattatcttcgtggtatacaccatgctccccttcaac
atgcgagacgccatcatcgccagcgtgctcacggcctcctcccacaccgtcgtgctgagc
atctgcctgtccgcaacgcccggggccaaggagcacctggtctggcagatcctggccaac
gtgatcattttcatctgtgggaacctggcgggagcgtaccacaagcaccttatggaactt
gctctgcagcagacgtaccaggacacgtgcaattgcatcaagtcccggatcaagctggaa
tttgaaaagcgtcagcaggagcgtctcctgctgtctctgttgccggctcacatagccatg
gagatgaaagctgagatcatccagaggctgcagggccccaaagccggccaaatggaaaac
acaaacaactttcacaacctgtatgtcaagcgacataccaatgtgagtatcctgtacgca
gacatcgttggcttcacccggttggccagtgactgctccccaggagaactggtccacatg
ctgaacgagctctttggaaagttcgatcaaattgcaaaggagaatgagtgcatgagaata
aaaattttgggagactgctactactgcgtgtccggactccccatatctctcccgaaccat
gccaagaattgtgtgaaaatgggactggatatgtgtgaagccataaagaaagtgagggac
gccaccggcgtggatatcaacatgcgcgtcggagtgcattctgggaacgtcctctgcggc
gtgatcggtctgcagaagtggcagtatgacgtgtggtcacatgacgttaccttagccaat
cacatggaagccggaggggttcctggacgtgttcacatttcttctgtcaccttggaacac
ttgaatggcgcttataaagtggaggaaggagatggtgacatcagagacccatatttaaaa
cagcacctggtgaaaacctactttgtaatcaaccctaagggggagcgacggagtcctcac
ctcttcagacctcgccacaccctcgatggagccaagatgagggcttccgtccgcatgacc
cggtacctggagtcctggggagcagccaagccctttgcacacctgcatcaccgagatagc
atgaccacggagaacggcaagatcagcaccacggatgtgccaatgggtcagcataatttt
caaaaccgtaccttaagaaccaagtcgcaaaagaagagatttgaggaagagttaaatgaa
aggatgattcaagcaattgatggaattaatgcacaaaagcagtggctcaagtctgaagac
attcagagaatctcgctcctgttctacaataaaatactagaaaaagaataccgagccacc
gcactgccagcgttcaagtattacgtgacctgcgcgtgtctcatattgttctgcattttt
atcgtgcagattctggtattacccaagacgtccattctcgggatctcctttggagccgca
tttctcttgcttgcctgtatccttttcgtctgctttgctggacagcttttgcaatgcagc
aagaaggcctctgcctctctcctgtggctgctgaagtcgtccagcatcatcgcggaccgg
ccctggccgcgggtctccctcacggtcctcaccaccgccatcatcctgaccatggccgtg
ttcaacatgtttttcctgagcgacccagaggaagccatgcctccgactgccaacacatca
aacacaagtctttctgccttaaacaatcaggcagtgattctgcgagcacagaatttgttt
ttcctcccgtactttatctacagctgcattctgggactgatttcctgctcggttttcctg
cgggtgaattacgagttgaaaatgctgatcatgatggcggcgttgataggctacaacacc
atccttctccacactcacgcccacgtcctggacgactacagccaggtcttatttgagaga
ccaggcatttggaaagacctgaagaccatgggctcagtgtctctctttatatttttcatc
acactgcttgttctgggtagacagaatgaatattactgtaggttagacttcttgtggaag
aacaagttcaaaaaagagcgggaggagatagaaaccatggagaacttgaaccgcgtgctg
ctggagaacgtgctgcccgcgcacgtggccgaacatttcctggcccggagcctgaagaac
gaggagttgtaccaccagtcctacgactgtgtctgtgtcatgtttgcttccattccggat
ttcaaggaattctacacagaatcggatgtgaacaaggagggcttggaatgccttcggctc
ctgaacgagatcatcgccgactttgatgatctgctgtccaagccgaaattcagtggagtt
gaaaagatcaagaccatcggcagcacgtatatggccgcgaccggtctgagcgccgtgccc
agccaggagcatacccaggagcccgagaggcagtacatgcatatcggcaccatggtggag
tttgcctttgccctggtggggaagctggacgctatcaacaaacactccttcaacgacttc
aagctgcgagtgggtattaaccatgggcctgtaatagccggtgtgattggagctcagaag
ccacaatacgatatctggggcaacaccgtgaatgtggccagcaggatggacagcaccggc
gtgctggacaaaatacaggtcactgaggagacaagcctcatcctccagaccctggggtac
acgtgcacgtgtcgaggaataatcaacgtgaaaggcaagggggagctgaagacgtacttt
gtaaacacggaaatgtcaaggtccctttcccagagcaacgtggcatcctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (50)   
   KEGG PATHWAY (50)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (7)   
   RefSeq(pep) (7)   
DNA sequence (8)   
   RefSeq(nuc) (8)   
Protein domain (4)   
   Pfam (4)   
All databases (84)   

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