KEGG   Pan troglodytes (chimpanzee): 460396Help
Entry
460396            CDS       T01005                                 

Gene name
CACNA2D2
Definition
calcium channel, voltage-dependent, alpha 2/delta subunit 2
Orthology
K04859  
voltage-dependent calcium channel alpha-2/delta-2
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
MAPK signaling pathway
Cardiac muscle contraction
Adrenergic signaling in cardiomyocytes
Oxytocin signaling pathway
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ptr00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    460396 (CACNA2D2)
 Organismal Systems
  Endocrine system
   04921 Oxytocin signaling pathway
    460396 (CACNA2D2)
  Circulatory system
   04260 Cardiac muscle contraction
    460396 (CACNA2D2)
   04261 Adrenergic signaling in cardiomyocytes
    460396 (CACNA2D2)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    460396 (CACNA2D2)
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    460396 (CACNA2D2)
   05414 Dilated cardiomyopathy (DCM)
    460396 (CACNA2D2)
Ion channels [BR:ptr04040]
 Voltage-gated cation channels
  Ca2+ channel, CACN alpha-2 delta
   460396 (CACNA2D2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
3
AA seq 1241 aa AA seqDB search
MELPCASDVRRVQSVGGGVLRDVANGVHPWMLLIDVVECRILNGNTLVPARICSTSRPGP
ARTARPWPGCGPQPGPGTRRPTSGPPRPLWLLLPPLLLLPLLAAPSASAYSFPQQHTMQH
WARRLEQEVDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLDRKVQ
ALKRLADAAENFQKAHRWQDNIKEEDIVYYDAKADAELDDPESEDVERGSKANTLRLDFI
EDPNFKNKVNYSYAAVQIPTDIYKGSTVILNELNWTEALENVFMENRRQDPTLLWQVFGS
ATGVTRYYPGRYQPLSPWALPXQRHLLGRYIQGASSPKDMVIIVDVSGSVSGLTLKLMKT
SVCEMLDTLSDDDYVNVASFNEKAQPVSCFTHLVQANVRNKKVFKEAVQGMVAKGTTGYK
AGFEYAFDQLQNSNITRANCNKMIMMFTDGGEDRVQDVFEKYNWPNRTVRVFTFSVGQHN
YDVTPLQWMACANKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAGKEAKQVQWTNVYEDA
LGLGLVVTGTLPVFNLTQDGPGEKKNQLILGVMGIDVALNDIKRLTPNYTLGANGYVFAI
DLNGYVLLHPNIKPQTTNFREPVTLDFLDAELEDENKEEIRRSMIDGNKGHKQIRTLVKS
LDEVRRQGWGPGRYIDEVTRNYTWVPIRSTNYSLPRDSLAFKEQAAGLRAQDSHQKSPHH
YXXXXADWGLISFEFSRSLFLSHVVFCKKFPFVPISKLKDFEFLLPSSFESEGHVFIAPR
EYCKDLNASDNNTEFLKNFIELMEKVTPDSKQCNNFLLHNLILDTGITQQLVERVWRDQD
LNTYSLLAVFAATDGGITRVFPNKAAEDWTENPEPFNASFYRRSLDNHGYVFKPPHQDAL
LRPLELENDTVGILVSTAVELSLGRRTLRPAVVGVKLDLEAWAEKFKVLASNRTHQDQPQ
KCGPNSHCEMDCEVNNEDLLCVLIDDGGFLVLSNQNHQWDQVGRFFSEVDANLMLALYNN
SFYTRKESYDYQAACAPQPPGNLGAAPRGVFVPTVADFLNLAWWTSAAAWSLFQQLLYGL
IYHSWFQADPAEAEGNPETRESSCVMKQTQYYFGSVNASYNAIIDCGNCSRLFHAQRLTN
TNLLFVVAEKPLCSQCEAGRLLQKETHSDGPEQCELVQRPRYRRGPHICFDYNATEDTSD
CGRGASFPPSLGVLVSLQLLLLLGLPPRPQPQVLVHASRRL
NT seq 3726 nt NT seq  +upstreamnt  +downstreamnt
atggagttgccatgtgccagtgatgtgcgccgggtgcagtctgttgggggtggggtgctc
agggacgtggccaacggagtccacccttggatgctccttatagatgtcgtggagtgccga
attttgaatggaaacacactagtgccggctcggatttgcagcacctctcggcccggccca
gcgcggactgcgcgcccctggcccggctgcggcccccagcctggccccggcacccggcgt
ccgacgtccgggcccccgcgcccgctgtggctgctgctgccgccgctgctgcttctaccg
ctgctcgccgcccccagcgcctctgcctacagcttcccccagcagcacacgatgcagcac
tgggcccggcgtctggagcaggaggtagacggcgtgatgcggatttttggaggcgtccag
cagctccgtgagatttacaaggacaaccggaacctgttcgaggtacaggagaatgagcct
cagaagttggtggagaaggtggcaggggacattgagagccttctggacaggaaggtgcag
gccctgaagagactggctgatgctgcagagaacttccagaaagcacaccgctggcaggac
aacatcaaggaggaagacatcgtgtactatgacgccaaggctgacgctgagctggatgac
cctgagagtgaggatgtggaaagggggtctaaggccaacaccctaaggctggacttcatc
gaggacccaaacttcaagaacaaggtcaactattcatacgcggctgtacagatccctacg
gacatctacaaaggctccactgtcatcctcaatgagctcaactggacagaggccctggag
aatgtgttcatggaaaaccgcagacaagaccccacactgctgtggcaggtcttcggcagc
gccacaggagtcactcgctactacccgggtaggtaccagcccctgtccccttgggcctta
ccctaacagaggcatctcctgggcaggtatatccagggggcctcgtcacccaaagacatg
gtcatcatcgtggatgtgagtggcagtgtgagtggcctgaccctgaagctgatgaagaca
tctgtctgcgagatgctggacacgctgtctgatgatgactatgtgaatgtggcctcgttc
aacgagaaggcacagcctgtgtcatgcttcacacacctggtgcaggccaatgtgcgcaac
aagaaggtgttcaaggaagctgtgcagggcatggtggccaagggcaccacaggctacaag
gccggctttgagtatgcctttgaccagctgcagaactccaacatcactcgggccaactgc
aacaagatgatcatgatgttcacggatggtggcgaggaccgcgtgcaggacgtctttgag
aagtacaattggccaaaccggacggtgcgcgtgtttactttctccgtggggcagcataac
tatgacgtcacaccgctgcagtggatggcctgtgccaacaaaggctactattttgagatc
ccttccatcggagccatccgcatcaacacacaggaatatctagatgtgttgggcaggccc
atggtgctggcaggcaaggaggccaagcaggtgcagtggaccaacgtgtatgaggatgca
ctgggactggggttggtggtaacagggaccctccctgttttcaacctgacacaggatggc
cctggggaaaagaagaaccagctgatcctgggcgtgatgggcattgacgtggctctgaat
gacatcaagaggctgacccccaactacacgcttggagccaacggctatgtgtttgccatt
gacctgaacggctacgtgttgctgcatcccaatatcaagccccagaccaccaacttccgg
gagcctgtgactctggacttcctggatgcggagctagaggatgagaacaaggaagagatc
cgtcggagcatgattgatggcaacaagggccacaagcagatcagaacgttggtcaagtcc
ctggatgaggtaaggaggcagggctgggggccagggaggtacatagatgaggtgacacgg
aactacacctgggtgcctataaggagcactaactacagtctgccaagagactccctggct
tttaaggaacaagcagcaggtctgagagcacaggacagtcatcaaaagtctcctcatcac
tacnnnnnnnnnntggccgactgggggctcatctcctttgagttttctcgctctctcttt
ctctctcatgtcgttttttgcaagaagtttcctttcgtgccaatcagcaaactgaaggat
tttgagttcctgctccccagcagctttgagtctgaaggacatgttttcattgctcccaga
gagtactgcaaggacctgaatgcctcagacaacaacaccgagttcctgaaaaactttatt
gagctcatggagaaagtgactccagactccaagcagtgcaacaacttccttctgcacaac
ctgatcttggacacgggcatcacgcagcagctggtagagcgtgtgtggagggaccaggat
ctcaacacgtacagcctactggccgtgtttgctgccacagacggtggcatcacccgagtc
ttccccaacaaggcagctgaggactggacagagaaccctgagcccttcaatgccagcttc
taccgccgcagcctggataaccacggttatgtcttcaagcccccacaccaggatgccctg
ttaaggccgctggagctggagaatgacaccgtgggcatcctcgtcagcacagctgtggag
ctcagcctaggcaggcgcacactgaggccagcagtggtgggcgtcaagctggacctagag
gcttgggctgagaagttcaaggtgctagccagcaaccgtacccaccaagaccagcctcag
aagtgcggccccaacagccactgtgagatggactgcgaggttaacaatgaggacttactg
tgtgtcctcattgatgatggaggattcctggtgctgtcaaaccagaaccatcagtgggac
caggtgggcaggttcttcagtgaggtggatgccaacctgatgctggcactctacaataac
tccttctacacccgcaaggagtcctatgactatcaggcagcctgtgcccctcagccccct
ggcaacctgggtgctgcaccccggggtgtctttgtgcccaccgttgcagatttccttaac
ctggcctggtggacctctgctgccgcctggtccctgttccagcagcttctctacggcctc
atctaccacagctggttccaagcagaccccgcggaggccgaggggaaccccgagacgcgc
gagagcagctgcgtcatgaaacagacccagtactacttcggctcggtaaacgcctcctac
aacgccatcatcgactgcggaaactgctccaggctgttccacgcgcagagactgaccaac
accaatcttctctttgtggtggccgagaagccgctgtgcagccagtgcgaggctggccgg
ctgctgcagaaggagacgcactcggacggcccggagcagtgtgagctagtgcagagaccg
cgataccggagaggcccgcacatctgcttcgactacaacgcgacagaagatacctcagac
tgtggccgcggggcctccttcccgccgtcgctgggcgtcctggtctccctgcaactgctg
ctcctcctgggcctgccgccccggccgcagcctcaagtcctcgtccacgcctctcgccgc
ctctga

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