KEGG   Pteropus vampyrus (large flying fox): 105290018
Entry
105290018         CDS       T07815                                 
Symbol
AMBRA1
Name
(RefSeq) activating molecule in BECN1-regulated autophagy protein 1 isoform X1
  KO
K17985  activating molecule in BECN1-regulated autophagy protein 1
Organism
pvp  Pteropus vampyrus (large flying fox)
Pathway
pvp04137  Mitophagy - animal
pvp04140  Autophagy - animal
pvp05010  Alzheimer disease
pvp05014  Amyotrophic lateral sclerosis
pvp05016  Huntington disease
pvp05017  Spinocerebellar ataxia
pvp05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:pvp00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    105290018 (AMBRA1)
   04137 Mitophagy - animal
    105290018 (AMBRA1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105290018 (AMBRA1)
   05014 Amyotrophic lateral sclerosis
    105290018 (AMBRA1)
   05016 Huntington disease
    105290018 (AMBRA1)
   05017 Spinocerebellar ataxia
    105290018 (AMBRA1)
   05022 Pathways of neurodegeneration - multiple diseases
    105290018 (AMBRA1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pvp04131]
    105290018 (AMBRA1)
   03029 Mitochondrial biogenesis [BR:pvp03029]
    105290018 (AMBRA1)
Membrane trafficking [BR:pvp04131]
 Autophagy
  Mitophagy
   PINK1-Parkin associated proteins
    105290018 (AMBRA1)
Mitochondrial biogenesis [BR:pvp03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    105290018 (AMBRA1)
SSDB
Motif
Pfam: WD40 ANAPC4_WD40 eIF2A Acyl_CoA_thio
Other DBs
NCBI-GeneID: 105290018
NCBI-ProteinID: XP_011355217
UniProt: A0A6P3Q6Y7
Position
Unknown
AA seq 1299 aa
MKVVPEKNAVRILWGRERGTRAFGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLA
FSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEV
RIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEM
ERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLL
HNFLHMLSSRSSGIQVGEQSTVQDSATPSPPPPPPQPSMERPRTSAYIRLRQRVSYPTAE
CCQHLGILCLCSRCSGTRVPSLLPHQDSVPPASARATTPSFSFVQTEPFHPPEQASSAQQ
DQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHREIAPGLTGSEWT
RTVLSLNSRSEAESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPASGLATE
SDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLNGEAPQTQQAQEMLNNNIEP
ERPGPSHQPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSW
QVPSTFEGMPSSGSQLPPLERTEGQTPSSSRLELSSSTSPQEERTVGVAFNQETGHWERI
YTQSSRSGTVSQEALHQDMPEESAEEDSLRRRLLESSLISLSRYDGAGSREHPIYPDPAR
LSPAAYYAQRMIQYLSRRDSIRQRSMRYQQNRLRSSTSSSSSDNQGPSVEGTDLEFEDFE
DNGDRSRHRAPRNARMSAPSLGRFVPRRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLA
GAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISAD
GQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGL
ASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEP
GLGLAYGTNKGDLVICRPEASNSGIEYYWDQLNETVFTVHSNSRSSERPGTSRATWRTDR
DMGLMNAIGLQPRNPTTSVTSQGTQTLALQLQNAETQTEREIQEPGTAAAGPGEGEGSEY
GASGEDALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTEPSA
ARTSSPQPSTSRGLLPEPGQLAERGLSPRTASWDQPGTPGREPPQPPLPSSSPAPTPVPL
PSTEGPTLHCNLTNNNPLPGGGGSSRGEAAGPSGEPRNR
NT seq 3900 nt   +upstreamnt  +downstreamnt
atgaaggttgttccagagaagaacgctgtccggatactctggggtcgagaacggggcact
cgggcctttggagcccagcggcttctgcaggagttggtggaagataaaacccggtggatg
aaatgggagggcaagagagtagaactgccggatagtccacgctctactttcttgctggcc
ttcagcccagacaggactcttttagcctctacccacgtgaaccataatatctacattacg
gaggtgaagactggcaagtgtgttcattctctgattggacaccgtcgcactccatggtgt
gtcacttttcatcccaccatctcaggcctcattgcttctggatgcctagatggggaggtt
aggatttgggatttacacggtggcagtgaaagctggttcacagatagcaacaatgctatt
gcctctttggctttccaccctacggctcagctcctgctgattgctactgccaatgagatc
cacttctgggattggagtcgacgggagccctttgctgtggtgaagacagctagcgagatg
gaacgggtccgtctggtgagatttgatcctcttggacactacttactcacagcaatcgtt
aacccctctaatcagcagggtgatgacgaaccagagattcccatagacggaacagaatta
tcccactaccgtcagcgtgccctcctgcaatcacagccagttcgccggacacctctcctc
cacaatttcctgcacatgctgtcctcccgctcctctggcatccaggtgggagagcaaagc
acagtgcaagattctgctaccccctcacccccaccgcctccccctcagccctccatggaa
cgccccaggacttccgcttacatcaggctccgacagcgggtcagttaccccacagctgag
tgctgccagcaccttgggatcctgtgcctttgcagccgctgctctggcactcgagttcct
tccctcttgccacaccaggacagtgttccccctgcttctgccagggctactaccccttcc
ttttcttttgtacagaccgagcccttccatcccccggagcaggcctcgtcagcgcagcag
gaccagggcctcctgaaccggccgtctgccttcagtacagtccagagcagcactgccggc
aacaccctccgcaacctcagtctgggtcccacccgtcgctctttgggaggccctttgtct
agccacccttctaggtatcaccgagaaatagctcctgggctgacaggatctgagtggacc
cggacagttctcagtctgaactcccgctctgaggcagaatccatgcccccgcccaggacc
agtgcctcgtccgtgagtttgctgtccgtgctgagacagcaggaaggtggctctcaagca
tctgtgtacacttcagctacagaagggagaggttttcccgcttcagggttggcaactgag
tcagatggagggaatggctccagccaaaacaactcaggcagcattcgccatgagcttcag
tgtgacctgagacgcttctttttggagtatgaccggcttcaggagctggaccagagcctg
aatggggaagccccccagacccaacaggcccaggaaatgctcaacaataacattgaacct
gagaggccaggcccctcccatcagcccaccccacacagcagtgagaacaactccaacctg
tcccgcggccacctgaatcgctgccgtgcttgccacaatctcctgacctttaacaacgat
accctgcgctgggaaagaaccacacctaactactcctctggtgaggccagttcatcctgg
caggtccccagtacctttgagggcatgccatcgagtggcagccagttgccacctctcgag
cggactgagggccaaacacccagctccagcaggctggagttgagcagctctactagtccg
caggaggagagaactgtgggagtggccttcaaccaggagacaggccactgggaaagaatt
tacacccaatccagcagatctggaactgtatcacaggaggccttacatcaggatatgcct
gaggaaagtgctgaggaagattcactcaggaggaggctgctggaatcttccctcatttca
ttatcccgttatgatggagcaggatccagagagcacccaatttacccagacccagcgaga
ttatctcctgctgcatactacgcccagaggatgatccagtatctctcacggagagacagt
attcgccagcgctccatgcgctaccaacagaaccgtcttcgttcttccacctcctcctct
tcctcagacaaccagggtccatcagtagagggaaccgacttggaatttgaggacttcgag
gacaatggtgacagatccaggcaccgagctccacgcaatgcccggatgtctgcaccttcg
cttggacgctttgtcccaaggcgtttcttgctgcccgagtacttgccttatgctggaatt
ttccatgaacgtggacagcctggcttggctactcactcttctgttaacagggtcctggca
ggggcggtgattggtgacggacagtctgctgtggccagtaacattgccaatactacctac
cggctccagtggtgggacttcactaaatttgacctcccagaaatcagtaatgcctccgtg
aatgtgctggtgcagaactgcaaaatctacaatgatgccagctgcgacatttctgcagac
ggccagctcctggcagctttcatccccagcagccaaaggggctttcccgatgaaggcatc
ttggcagtgtactccctggccccccacaacttgggtgaaatgctctacaccaagcgattt
ggtcccaatgccatttcagtgagcctgtccccaatgggccgatatgtaatggtgggcttg
gcctcacgaaggatcctgctgcacccctccacagaacacatggtggcccaggtcttcagg
ctgcagcaggcccatggtggtgagacctccatgaggagagttttcaacgtcctttacccc
atgcctgctgaccagcggagacatgtcagcatcaactctgcacgttggctacctgagccc
gggctcggcctggcctatggcacgaacaaaggagacctggtgatctgccgaccagaggcc
tcaaactctggtattgagtactactgggaccagctgaacgagactgtcttcactgtccac
tccaacagccggagcagtgaaaggcctggaaccagcagagccacatggaggacagacaga
gacatgggtctgatgaatgcaattggtctacagccccggaaccccaccacctcagtaacg
tctcagggcacccaaactctggccctccagctgcagaatgccgaaacacagacggagagg
gagatacaggagccagggacagcagctgcaggtcctggggaaggtgagggctcagagtac
ggtgcaagtggggaagacgccctcagcaggatccagcggctgatggcagaagggggcatg
acagctgtggtgcagcgggagcagagcaccaccatggcctccatgggtggcttcggcaac
aacatcatcgtcagccaccgcattcaccgcagctcccagacaggcactgagcccagtgcc
gcccgtacctcctcgccccagccttccacctctcggggactgctcccggaacctggacaa
ctggcagagcgaggcctaagccctcggacagcctcctgggaccagcctggtacccctggg
cgggagccaccccagccacccctgccctcttcctcccctgcccctactcctgttcccctt
cccagcactgagggaccaaccctgcactgcaacctgaccaataataaccctcttcctggc
ggtggtggcagcagcaggggggaagctgctggccccagtggggagccacggaacaggtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (10)   
   UniProt (1)   
   RefSeq(pep) (9)   
DNA sequence (9)   
   RefSeq(nuc) (9)   
Protein domain (4)   
   Pfam (4)   
All databases (37)   

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