KEGG   Pyrobaculum ferrireducens: P186_1854
Entry
P186_1854         CDS       T01670                                 
Name
(GenBank) pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase)
  KO
K00382  dihydrolipoyl dehydrogenase [EC:1.8.1.4]
Organism
pyr  Pyrobaculum ferrireducens
Pathway
pyr00010  Glycolysis / Gluconeogenesis
pyr00020  Citrate cycle (TCA cycle)
pyr00260  Glycine, serine and threonine metabolism
pyr00280  Valine, leucine and isoleucine degradation
pyr00310  Lysine degradation
pyr00380  Tryptophan metabolism
pyr00620  Pyruvate metabolism
pyr00630  Glyoxylate and dicarboxylate metabolism
pyr00640  Propanoate metabolism
pyr00785  Lipoic acid metabolism
pyr01100  Metabolic pathways
pyr01110  Biosynthesis of secondary metabolites
pyr01120  Microbial metabolism in diverse environments
pyr01200  Carbon metabolism
pyr01210  2-Oxocarboxylic acid metabolism
pyr01240  Biosynthesis of cofactors
Module
pyr_M00009  Citrate cycle (TCA cycle, Krebs cycle)
pyr_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
pyr_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:pyr00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    P186_1854
   00020 Citrate cycle (TCA cycle)
    P186_1854
   00620 Pyruvate metabolism
    P186_1854
   00630 Glyoxylate and dicarboxylate metabolism
    P186_1854
   00640 Propanoate metabolism
    P186_1854
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    P186_1854
   00280 Valine, leucine and isoleucine degradation
    P186_1854
   00310 Lysine degradation
    P186_1854
   00380 Tryptophan metabolism
    P186_1854
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    P186_1854
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:pyr04147]
    P186_1854
Enzymes [BR:pyr01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.1  With NAD+ or NADP+ as acceptor
    1.8.1.4  dihydrolipoyl dehydrogenase
     P186_1854
Exosome [BR:pyr04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   P186_1854
SSDB
Motif
Pfam: Pyr_redox_2 Pyr_redox_dim Pyr_redox GIDA Pyr_redox_3 FAD_oxidored NAD_binding_8 HI0933_like AlaDh_PNT_C FAD_binding_2 FAD_binding_3 Trp_halogenase DAO Lycopene_cycl 3HCDH_N Thi4 NAD_binding_9
Other DBs
NCBI-ProteinID: AET33258
UniProt: G7VHG7
Position
1562330..1563688
AA seq 452 aa
MRLVVVGGGPAGYVAAIRASQLGIKVTLIEAEHLGGECTNYACIPSKALLHAAEVYRKAA
SAPWLAGSLSFRWGEAVRWKDGVVERLRRGIEFLLKSAGVEVVHGVAKPGPGKSVEVNGR
RFEYDYLLLATGSEPVDLKELPRGGRVLGTREVFGLENAPASVAIIGGGAAGVEAASLFS
MLGSEVHLVEVMDRLLPGLDADVSRQVERALAGRGVKVYTSSRVVGAGGADGALELRLST
PGGEKRVEVEIAVVAVGRRPRLGPFAALGLELDSRGAVKTDSSMRTSIPWVYAAGDVTGP
PYYAHKAYAQAKAAVENMAGLKSAYEPRAVPAVIFSDPEVVSVGLTEEEAAKRGYRPKAA
RVPLSALGRAVATDSSEGFAKLVYDGESRVVLGVHMVGRGVSELAGEAAALVEFYATVDD
LALVVHPHPTLSELFVELAEAALGRPTHVARL
NT seq 1359 nt   +upstreamnt  +downstreamnt
atgaggcttgtggtggtcggcggcgggcccgccggctacgtcgcggccattagggcgagc
cagctgggcatcaaggtcacgttgatagaggcggagcacctaggcggggagtgtacaaac
tacgcatgcatcccctccaaggcgttgctacacgccgcggaggtttacagaaaggcggct
tcagccccgtggctggccggctctctgtcgtttaggtggggggaagccgttcgctggaag
gacggggtggtggagaggcttaggcgcggcatagagttcctcttgaagtcggccggggtt
gaggttgtacacggcgtcgccaagccggggccggggaagtcggttgaagtgaacggccgg
aggtttgagtacgactacctgcttctagccactggtagcgagcccgtagatctgaaggag
ctaccccgcggggggagggtccttgggactagggaggtcttcggtctagaaaacgcaccg
gcgtctgtggcgattatcggcgggggcgccgccggcgtggaggcggcgtctctcttttca
atgttaggctctgaggtccacctagtcgaggtgatggatcggctactgccggggctcgac
gcagatgtgtctaggcaggttgagagggcgctcgctggaagaggcgttaaggtgtacacc
tcctcaagggttgtgggcgccggcggcgcagacggcgcgttggagctacgcctctccacg
cccggcggggagaagagggtggaggtggagatagccgtcgtggcggtggggaggcgcccg
aggctcgggcccttcgccgcgctggggctggagctggacagccgcggcgccgtgaagaca
gacagctcgatgaggacgagcatcccgtgggtatacgccgcgggggacgtgactgggccg
ccgtactacgcccacaaggcctacgcccaggctaaggccgcggtggagaacatggcgggc
ctcaagtcggcctacgagccccgtgccgtgccggcggtgatcttcagcgaccccgaggtg
gtgtctgtgggcctcaccgaggaggaggccgccaagaggggttacagacccaaggcggcg
agggtgcccctttcggcgcttgggcgcgcggtggccaccgactcgtctgagggattcgcc
aagcttgtgtacgacggggagagccgcgtcgtgctgggcgtccacatggtggggcgcggc
gtctctgaactggccggcgaagccgccgccctagtcgagttctacgccacagtcgacgac
ttggcgctggtggtgcacccacacccaactctctctgagctcttcgtcgagctggcggag
gccgccctcgggaggcccacacacgtggcgaggttatga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (23)   
   KEGG PATHWAY (16)   
   KEGG MODULE (7)   
Chemical substance (27)   
   KEGG COMPOUND (27)   
Chemical reaction (11)   
   KEGG ENZYME (1)   
   KEGG REACTION (10)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (17)   
   Pfam (17)   
All databases (86)   

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