KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108515083
Entry
108515083         CDS       T04641                                 
Name
(RefSeq) steroid 17-alpha-hydroxylase/17,20 lyase
  KO
K00512  steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb00140  Steroid hormone biosynthesis
rbb01100  Metabolic pathways
rbb04913  Ovarian steroidogenesis
rbb04917  Prolactin signaling pathway
rbb04927  Cortisol synthesis and secretion
rbb04934  Cushing syndrome
Module
rbb_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
rbb_M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
rbb_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
rbb_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    108515083
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    108515083
   04917 Prolactin signaling pathway
    108515083
   04927 Cortisol synthesis and secretion
    108515083
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    108515083
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:rbb00199]
    108515083
Enzymes [BR:rbb01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.19  steroid 17alpha-monooxygenase
     108515083
    1.14.14.32  17alpha-hydroxyprogesterone deacetylase
     108515083
Cytochrome P450 [BR:rbb00199]
 Cytochrome P450, animal type
  CYP17 family
   108515083
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 108515083
NCBI-ProteinID: XP_017707160
UniProt: A0A2K6MHI1
Position
Unknown
AA seq 508 aa
MWELVALLLLTLAYLFWPKRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFNLQKKY
GPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQVTTLDILSNNRKGIAFADYGAH
WQLHRRLAMATFALFKDGDQKLERIICQEISTLCDMLATHNGQTIDISFPVFMAVTNVIS
LICFNISYKNGDPELKIVQNYNEGIIDSLGKESLVDLFPWLKVFPNKTLEKLKGHVKTRN
DLLAKIFENYKEKFRSDSITNMLDILMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIF
GAGVETTTSVVKWIVAFLLHNPQVMKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREV
LRIRPVAPMLIPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEWHQPDQFMPERFLNP
AGTQLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGNP
KVVFLIDSFKVKIKVRQAWREAQAEGST
NT seq 1527 nt   +upstreamnt  +downstreamnt
atgtgggagcttgtggctctcttgctgctcaccctagcctatttattttggcccaagaga
aggtgccctggtgccaagtatcctaagagcctcctgtccctgcccctggtgggcagcctg
ccattcctccccagacatggccatatgcataacaactttttcaacctgcagaaaaaatat
ggccccatctattccgttcgtatgggcaccaagactacagtgattgtcggccaccaccag
ctggccaaggaggtgcttattaagaagggcaaggacttctctgggcggcctcaagtgaca
actctagacatcctgtccaacaaccgtaagggtattgccttcgctgactacggcgcacat
tggcagctgcatcgaaggctggcgatggccacctttgccctgttcaaggatggcgatcag
aagctggagaggatcatttgtcaggaaatcagtacattgtgtgatatgctggccacccac
aacggacagaccatagacatctcctttcctgtcttcatggcggtaaccaacgtcatctcc
ttgatctgcttcaacatctcctacaagaatggggaccctgagttgaagattgtacagaat
tacaatgaaggcatcatagacagcctgggcaaggagagcctggtggacctattcccctgg
ttgaaggttttccccaacaaaactctggaaaaattaaaggggcatgttaaaacacgaaat
gatctgctggctaaaatatttgaaaattacaaggagaaattccgcagtgactctatcacc
aacatgctggacatactgatgcaagccaagatgaattcagataatggcaacgctggccca
gatcaagactcagagctgctttcagataaccacattctcaccaccataggggacatcttt
ggggctggcgtggagaccaccacctctgtggtgaaatggatcgtggccttcctgctgcac
aatcctcaggtgatgaagaagctctacgaggagattgaccagaatgtgggtttcagccgc
acaccaaccatcagtgaccgtaaccgtcttctcctgctggaggccaccatccgagaggtg
cttcgcatcaggcccgtggcccctatgctcatcccccacaaggccaacgttgactccagc
atcggtgagtttgctgtggacaagggcacacatgttatcatcaatctgtgggcgctgcat
cacaatgagaaggagtggcaccagccggaccagttcatgcctgagcgtttcttgaatcca
gcggggacccagctcatctcaccgtcattaagctacttgcccttcggagcaggacctcgc
tcctgtataggtgagatcctggcccgccaggagctctttctcatcatggcctggctgctg
cagaggttcgacctggaggtgccagatgacgggcagctgccctccctggaaggcaaccca
aaggtggtctttctgatcgactctttcaaagtgaagatcaaagtgcgccaggcctggagg
gaagcccaggctgagggtagcacctaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (10)   
   KEGG PATHWAY (6)   
   KEGG MODULE (4)   
Chemical substance (20)   
   KEGG COMPOUND (20)   
Chemical reaction (11)   
   KEGG ENZYME (2)   
   KEGG REACTION (9)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (1)   
   Pfam (1)   
All databases (53)   

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