LOCUS       WP_014867813             193 aa            linear   BCT 27-DEC-2023
DEFINITION  carbonic anhydrase [Methanoculleus bourgensis].
ACCESSION   WP_014867813
VERSION     WP_014867813.1
KEYWORDS    RefSeq.
SOURCE      Methanoculleus bourgensis
  ORGANISM  Methanoculleus bourgensis
            Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
            Methanomicrobiales; Methanomicrobiaceae; Methanoculleus.
REFERENCE   1  (residues 1 to 193)
  AUTHORS   Kimber,M.S. and Pai,E.F.
  TITLE     The active site architecture of Pisum sativum beta-carbonic
            anhydrase is a mirror image of that of alpha-carbonic anhydrases
  JOURNAL   EMBO J 19 (7), 1407-1418 (2000)
   PUBMED   10747009
REFERENCE   2  (residues 1 to 193)
  AUTHORS   Guilloton,M.B., Korte,J.J., Lamblin,A.F., Fuchs,J.A. and
            Anderson,P.M.
  TITLE     Carbonic anhydrase in Escherichia coli. A product of the cyn operon
  JOURNAL   J Biol Chem 267 (6), 3731-3734 (1992)
   PUBMED   1740425
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF012696.4
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF00484.23
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..193
                     /organism="Methanoculleus bourgensis"
                     /db_xref="taxon:83986"
     Protein         1..193
                     /product="carbonic anhydrase"
                     /function="Carbonic anhydrase"
                     /GO_function="GO:0004089 - carbonate dehydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence
                     IEA]"
                     /calculated_mol_wt=21980
     Region          8..189
                     /region_name="beta_CA"
                     /note="Carbonic anhydrases (CA) are zinc-containing
                     enzymes that catalyze the reversible hydration of carbon
                     dioxide in a two-step mechanism in which the nucleophilic
                     attack of a zinc-bound hydroxide ion on carbon dioxide is
                     followed by the regeneration of an...; cl00391"
                     /db_xref="CDD:444882"
     Site            order(31,33,40,42..44,56,59,81,86,96,99,182)
                     /site_type="active"
                     /note="active site clefts [active]"
                     /db_xref="CDD:238224"
     Site            order(40,42,96,99)
                     /site_type="other"
                     /note="zinc binding site [ion binding]"
                     /db_xref="CDD:238224"
     Site            order(41..44,51,56..58,60,62,80..81,182,184..185,187,189)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238224"
ORIGIN      
        1 miekflegne rfreddfkkn pdhynalass qhpvvlwigc sdsrvdperi tgaqageifv
       61 qrnignivpv hdwnfatvle yalnhlqvgd ivicghsdcg aikgldhesd dayvplwlnn
      121 ameakrrvet riqvpktpee edlrrrliei envglqlehl rtyppvraae kegrvrlhgl
      181 yfdlatgelk kif
//