LOCUS       WP_025236074             415 aa            linear   BCT 24-DEC-2024
DEFINITION  sialidase family protein [Mannheimia sp. USDA-ARS-USMARC-1261].
ACCESSION   WP_025236074
VERSION     WP_025236074.1
KEYWORDS    RefSeq.
SOURCE      Mannheimia sp. USDA-ARS-USMARC-1261
  ORGANISM  Mannheimia sp. USDA-ARS-USMARC-1261
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pasteurellales; Pasteurellaceae; Mannheimia.
REFERENCE   1  (residues 1 to 415)
  AUTHORS   Coines,J., Raich,L. and Rovira,C.
  TITLE     Modeling catalytic reaction mechanisms in glycoside hydrolases
  JOURNAL   Curr Opin Chem Biol 53, 183-191 (2019)
   PUBMED   31731209
REFERENCE   2  (residues 1 to 415)
  AUTHORS   Naumoff,D.G.
  TITLE     Hierarchical classification of glycoside hydrolases
  JOURNAL   Biochemistry (Mosc) 76 (6), 622-635 (2011)
   PUBMED   21639842
REFERENCE   3  (residues 1 to 415)
  AUTHORS   Vuong,T.V. and Wilson,D.B.
  TITLE     Glycoside hydrolases: catalytic base/nucleophile diversity
  JOURNAL   Biotechnol Bioeng 107 (2), 195-205 (2010)
   PUBMED   20552664
REFERENCE   4  (residues 1 to 415)
  AUTHORS   Taylor,G.
  TITLE     Sialidases: structures, biological significance and therapeutic
            potential
  JOURNAL   Curr Opin Struct Biol 6 (6), 830-837 (1996)
   PUBMED   8994884
REFERENCE   5  (residues 1 to 415)
  AUTHORS   Davies,G. and Henrissat,B.
  TITLE     Structures and mechanisms of glycosyl hydrolases
  JOURNAL   Structure 3 (9), 853-859 (1995)
   PUBMED   8535779
REFERENCE   6  (residues 1 to 415)
  AUTHORS   Henrissat,B., Callebaut,I., Fabrega,S., Lehn,P., Mornon,J.P. and
            Davies,G.
  TITLE     Conserved catalytic machinery and the prediction of a common fold
            for several families of glycosyl hydrolases
  JOURNAL   Proc Natl Acad Sci U S A 92 (15), 7090-7094 (1995)
   PUBMED   7624375
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 1996 May 28;93(11):5674. doi:
            10.1073/pnas.93.11.5674. PMID: 8643635]
REFERENCE   7  (residues 1 to 415)
  AUTHORS   Roggentin,P., Schauer,R., Hoyer,L.L. and Vimr,E.R.
  TITLE     The sialidase superfamily and its spread by horizontal gene
            transfer
  JOURNAL   Mol Microbiol 9 (5), 915-921 (1993)
   PUBMED   7934919
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11468221
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Mannheimia sp. USDA-ARS-USMARC-1261"
                     /db_xref="taxon:1432056"
     Protein         1..415
                     /product="sialidase family protein"
                     /EC_number="3.2.1.-"
                     /GO_function="GO:0004308 - exo-alpha-sialidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=46928
     Region          <152..403
                     /region_name="NanH"
                     /note="Neuraminidase (sialidase) NanH, contains C-terminal
                     autotransporter domain [Carbohydrate transport and
                     metabolism, Cell wall/membrane/envelope biogenesis];
                     COG4409"
                     /db_xref="CDD:443531"
ORIGIN      
        1 midlieqpyn apnfentqsa fvidpvmvqd knserifllv dmypessgih shityhgkre
       61 panpanalgs gytkidgqaf lkligkdqty tlrkqshtlg rvydtqnnpt dyqvvtkgnp
      121 dkayrdlgdv ylgemndany qgniflssqk efnrsapftv qktsylwliy sddngktwsn
      181 pidlnpqlkt dsmkflgtgp gtgvqlesgt llvpvyfidq ydneltavik sedggetwlm
      241 getpikfngn kapykasesh ivelndgtit lftrtnkgnv lvsssntegm twqssefdae
      301 llnsytqlsa ikyskeindk eyvllsnahs kqmwkringr vwigeiksdn tidwqdyiqi
      361 tddnetfgys siaelpdgkv gllyekvgge iryvrleveq ilkddrlnny krsff
//